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Volumn 240, Issue 4, 2004, Pages 667-676

Systemic siRNA-mediated gene silencing: A new approach to targeted therapy of cancer

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 6; CD34 ANTIGEN; CELL ADHESION MOLECULE; KI 67 ANTIGEN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 4644316534     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.sla.0000140755.97224.9a     Document Type: Conference Paper
Times cited : (104)

References (30)
  • 1
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA III, Moore MJ, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol. 1997;15:2403-2413.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Andersen, J.3
  • 2
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 3
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon GJ. RNA interference. Nature. 2002;418:244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 4
    • 0026048664 scopus 로고
    • Carcinoembryonic antigen gene family: Molecular biology and clinical perspectives
    • Thompson JA, Grunert F, Zimmermann W. Carcinoembryonic antigen gene family: molecular biology and clinical perspectives. J Clin Lab Anal. 1991;5:344-366.
    • (1991) J Clin Lab Anal , vol.5 , pp. 344-366
    • Thompson, J.A.1    Grunert, F.2    Zimmermann, W.3
  • 5
    • 0034798725 scopus 로고    scopus 로고
    • Identification and comparison of residues critical for cell-adhesion activities of two neutrophil CD66 antigens, CEACAM6 and CEACAM8
    • Kuroki M, Abe H, Imakiirei T, et al. Identification and comparison of residues critical for cell-adhesion activities of two neutrophil CD66 antigens, CEACAM6 and CEACAM8. J Leukoc Biol. 2001;70:543-550.
    • (2001) J Leukoc Biol , vol.70 , pp. 543-550
    • Kuroki, M.1    Abe, H.2    Imakiirei, T.3
  • 6
    • 0142008426 scopus 로고    scopus 로고
    • Expression of CEACAM6 in resectable colorectal cancer: A factor of independent prognostic significance
    • Jantscheff P, Terracciano L, Lowy A, et al. Expression of CEACAM6 in resectable colorectal cancer: a factor of independent prognostic significance. J Clin Oncol. 2003;21:3638-3646.
    • (2003) J Clin Oncol , vol.21 , pp. 3638-3646
    • Jantscheff, P.1    Terracciano, L.2    Lowy, A.3
  • 7
    • 0027158272 scopus 로고
    • Expression of carcinoembryonic antigen (CEA) and nonspecific crossreacting antigen (NCA) in gastrointestinal cancer; the correlation with degree of differentiation
    • Kodera Y, Isobe K, Yamauchi M, et al. Expression of carcinoembryonic antigen (CEA) and nonspecific crossreacting antigen (NCA) in gastrointestinal cancer; the correlation with degree of differentiation. Br J Cancer. 1993;68:130-136.
    • (1993) Br J Cancer , vol.68 , pp. 130-136
    • Kodera, Y.1    Isobe, K.2    Yamauchi, M.3
  • 8
    • 0027447983 scopus 로고
    • Nonspecific crossreacting antigen (NCA) is a major member of the carcinoembryonic antigen (CEA)-related gene family expressed in lung cancer
    • Hasegawa T, Isobe K, Tsuchiya Y, et al. Nonspecific crossreacting antigen (NCA) is a major member of the carcinoembryonic antigen (CEA)-related gene family expressed in lung cancer. Br J Cancer. 1993;67:58-65.
    • (1993) Br J Cancer , vol.67 , pp. 58-65
    • Hasegawa, T.1    Isobe, K.2    Tsuchiya, Y.3
  • 9
    • 0036118491 scopus 로고    scopus 로고
    • Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation
    • Ilantzis C, DeMarte L, Screaton RA, et al. Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation. Neoplasia. 2002;4:151-163.
    • (2002) Neoplasia , vol.4 , pp. 151-163
    • Ilantzis, C.1    DeMarte, L.2    Screaton, R.A.3
  • 10
    • 0033873631 scopus 로고    scopus 로고
    • Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas
    • Scholzel S, Zimmermann W, Schwarzkopf G, et al. Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol. 2000;156:595-605.
    • (2000) Am J Pathol , vol.156 , pp. 595-605
    • Scholzel, S.1    Zimmermann, W.2    Schwarzkopf, G.3
  • 11
    • 0842329842 scopus 로고    scopus 로고
    • CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells
    • Duxbury MS, Ito H, Zinner MJ, et al. CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells. Oncogene. 2004;23:465-473.
    • (2004) Oncogene , vol.23 , pp. 465-473
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3
  • 12
    • 0025319453 scopus 로고
    • Binding and biological effects of tumor necrosis factor and gamma interferon in human pancreatic carcinoma cells
    • Raitano AB, Scuderi P, Korc M. Binding and biological effects of tumor necrosis factor and gamma interferon in human pancreatic carcinoma cells. Pancreas. 1990;5:267-277.
    • (1990) Pancreas , vol.5 , pp. 267-277
    • Raitano, A.B.1    Scuderi, P.2    Korc, M.3
  • 13
    • 0037224197 scopus 로고    scopus 로고
    • Efficacy of camptothecin analog DX-8951f (Exatecan Mesylate) on human pancreatic cancer in an orthotopic metastatic model
    • Sun FX, Tohgo A, Bouvet M, et al. Efficacy of camptothecin analog DX-8951f (Exatecan Mesylate) on human pancreatic cancer in an orthotopic metastatic model. Cancer Res. 2003;63:80-85.
    • (2003) Cancer Res , vol.63 , pp. 80-85
    • Sun, F.X.1    Tohgo, A.2    Bouvet, M.3
  • 14
    • 0024330777 scopus 로고
    • An exponential-Gompertzian description of LoVo cell tumor growth from in vivo and in vitro data
    • Demicheli R, Foroni R, Ingrosso A, et al. An exponential-Gompertzian description of LoVo cell tumor growth from in vivo and in vitro data. Cancer Res. 1989;49:6543-6546.
    • (1989) Cancer Res , vol.49 , pp. 6543-6546
    • Demicheli, R.1    Foroni, R.2    Ingrosso, A.3
  • 15
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol. 1994;124:619-626.
    • (1994) J Cell Biol , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 16
    • 0015907856 scopus 로고
    • The deficient density-dependent growth control of human malignant glioma cells and virus-transformed glia-like cells in culture
    • Westermark B. The deficient density-dependent growth control of human malignant glioma cells and virus-transformed glia-like cells in culture. Int J Cancer. 1973;12:438-451.
    • (1973) Int J Cancer , vol.12 , pp. 438-451
    • Westermark, B.1
  • 17
    • 0033919727 scopus 로고    scopus 로고
    • Apoptosis, anoikis and their relevance to the pathobiology of colon cancer
    • Shanmugathasan M, Jothy S. Apoptosis, anoikis and their relevance to the pathobiology of colon cancer. Pathol Int. 2000;50:273-279.
    • (2000) Pathol Int , vol.50 , pp. 273-279
    • Shanmugathasan, M.1    Jothy, S.2
  • 18
    • 0033109535 scopus 로고    scopus 로고
    • Adhesion-mediated signaling in the regulation of mammary epithelial cell survival
    • Streuli CH, Gilmore AP. Adhesion-mediated signaling in the regulation of mammary epithelial cell survival. J Mammary Gland Biol Neoplasia. 1999;4:183-191.
    • (1999) J Mammary Gland Biol Neoplasia , vol.4 , pp. 183-191
    • Streuli, C.H.1    Gilmore, A.P.2
  • 19
    • 0032554769 scopus 로고    scopus 로고
    • Prolonged cell survival enhances peritoneal dissemination of gastric cancer cells
    • Yawata A, Adachi M, Okuda H, et al. Prolonged cell survival enhances peritoneal dissemination of gastric cancer cells. Oncogene. 1998;16:2681-2686.
    • (1998) Oncogene , vol.16 , pp. 2681-2686
    • Yawata, A.1    Adachi, M.2    Okuda, H.3
  • 20
    • 0242493171 scopus 로고    scopus 로고
    • RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine
    • Duxbury MS, Ito H, Zinner MJ, et al. RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene. 2003;311:786-792.
    • (2003) Oncogene , vol.311 , pp. 786-792
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3
  • 21
    • 0242493171 scopus 로고    scopus 로고
    • RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity
    • Duxbury MS, Ito H, Benoit E, et al. RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity. Biochem Biophys Res Commun. 2003;311:786-792.
    • (2003) Biochem Biophys Res Commun , vol.311 , pp. 786-792
    • Duxbury, M.S.1    Ito, H.2    Benoit, E.3
  • 22
    • 1442308345 scopus 로고    scopus 로고
    • EphA2: A determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma
    • Duxbury MS, Ito H, Zinner MJ, et al. EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma. Oncogene. 2004;23:1448-1456.
    • (2004) Oncogene , vol.23 , pp. 1448-1456
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3
  • 23
    • 0042173218 scopus 로고    scopus 로고
    • SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
    • Filleur S, Courtin A, Ait-Si-Ali S, et al. SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res. 2003;63:3919-3922.
    • (2003) Cancer Res , vol.63 , pp. 3919-3922
    • Filleur, S.1    Courtin, A.2    Ait-Si-Ali, S.3
  • 24
    • 0037348329 scopus 로고    scopus 로고
    • RNA interference targeting Fas protects mice from fulminant hepatitis
    • Song E, Lee SK, Wang J, et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med. 2003;9:347-351.
    • (2003) Nat Med , vol.9 , pp. 347-351
    • Song, E.1    Lee, S.K.2    Wang, J.3
  • 25
    • 0038610713 scopus 로고    scopus 로고
    • Caspase 8 small interfering RNA prevents acute liver failure in mice
    • Zender L, Hutker S, Liedtke C, et al. Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc Natl Acad Sci U S A. 2003;100:7797-7802.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7797-7802
    • Zender, L.1    Hutker, S.2    Liedtke, C.3
  • 26
    • 0036385852 scopus 로고    scopus 로고
    • Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
    • Bertrand JR, Pottier M, Vekris A, et al. Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem Biophys Res Commun. 2002;296:1000-1004.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 1000-1004
    • Bertrand, J.R.1    Pottier, M.2    Vekris, A.3
  • 27
    • 0037280401 scopus 로고    scopus 로고
    • RNA interference may be more potent than antisense RNA in human cancer cell lines
    • Aoki Y, Cioca DP, Oidaira H, et al. RNA interference may be more potent than antisense RNA in human cancer cell lines. Clin Exp Pharmacol Physiol. 2003;30:96-102.
    • (2003) Clin Exp Pharmacol Physiol , vol.30 , pp. 96-102
    • Aoki, Y.1    Cioca, D.P.2    Oidaira, H.3
  • 28
    • 0025653869 scopus 로고
    • Leaky tumor vessels: Consequences for tumor stroma generation and for solid tumor therapy
    • Dvorak HF. Leaky tumor vessels: consequences for tumor stroma generation and for solid tumor therapy. Prog Clin Biol Res. 1990;354A: 317-330.
    • (1990) Prog Clin Biol Res , vol.354 A , pp. 317-330
    • Dvorak, H.F.1
  • 29
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumor-igenicity by virus-mediated RNA interference
    • Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumor-igenicity by virus-mediated RNA interference. Cancer Cell. 2002;2:243-247.
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 30
    • 0037158901 scopus 로고    scopus 로고
    • Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
    • Wilda M, Fuchs U, Wossmann W, et al. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene. 2002;21:5716-5724.
    • (2002) Oncogene , vol.21 , pp. 5716-5724
    • Wilda, M.1    Fuchs, U.2    Wossmann, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.