Protein transport into canine pancreatic microsomes: A quantitative approach

European Journal of Biochemistry

Volumn 271, Issue 15, 2004, Pages 3200-3207

  Guth, Silvia ^a   Völzing, Christian ^a   Müller, Anika ^a   Jung, Martin ^a   Zimmermann, Richard ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Endoplasmic reticulum; Mammalian microsomes; Pancreas; Protein secretion; Protein transport

Indexed keywords

CARRIER PROTEIN; DOCKING PROTEIN; LUCIFERASE; MEMBRANE PROTEIN;

ARTICLE; DOG; ENDOPLASMIC RETICULUM; MICROSOME; NONHUMAN; PANCREAS CELL; PRIORITY JOURNAL; PROTEIN TRANSPORT; STOICHIOMETRY;

ANIMALS; CELL-FREE SYSTEM; DOGS; ENDOPLASMIC RETICULUM; HUMANS; MEMBRANE PROTEINS; MICROSOMES; PANCREAS; PROTEIN TRANSPORT;

CANIS FAMILIARIS; MAMMALIA;

EID: 3242892326     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04252.x     Document Type: Article

References (36)

1. Blobel, G. & Dobberstein, B. (1975) Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. J. Cell Biol. 67, 835-851.
2. Perara, E., Rothman, R.E. & Lingappa, V.R. (1986) Uncoupling translocation from translation: implications for transport of proteins across membranes. Science 232, 348-352.
3. Walter, P. & Blobel, G. (1981) Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein, SRP, mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein. J. Cell Biol. 91, 551-556.
4. Meyer, D.I., Krause, E. & Dobberstein, B. (1982) Secretory protein translocation across membranes - the role of the 'docking protein'. Nature 297, 647-650.
5. Görlich, D. & Rapoport, T.A. (1993) Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane. Cell 75, 615-630.
6. Kalies, K.-U., Görlich, D. & Rapoport, T.A. (1994) Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex. J. Cell Biol. 126, 925-934.
7. Jungnickel, B. & Rapoport, T.A. (1995) A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane. Cell 82, 261-270.
8. Hanein, D., Matlack, K.E.S., Jungnickel, B., Plath, K., Kalies, K.-U., Miller, K.R., Rapoport, T.A. & Akey, C.W. (1996) Oligomeric rings of the Secolp complex induced by ligands required for protein translocation. Cell 87, 721-732.
9. Tyedmers, J., Lerner, M., Bies, C., Dudek, J., Skowronek, M., Haas, I., Heim, N., Nastainczyk, W., Volkmer, J. & Zimmermann, R. (2000) Homologs of the yeast Sec complex subunits Sec62p and Sec63p are abundant proteins in dog pancreas microsomes. Proc. Natl Acad. Sci. USA 97, 7214-7219.
10. Beckmann, R., Bubeck, D., Grassucci, R., Penczek, P., Verschoor, A., Blobel, G. & Frank, J. (1997) Alignment of conduits for the nascent polypeptide chain in the ribosome-Secol complex. Science 278, 2123-2126.
11. Beckmann, R., Spahn, C.M., Eswar, N., Helmers, J., Penczek, P.A., Sali, A., Frank, J. & Blobel, G. (2001) Architecture of the protein-conducting channel associated with the translating 80S ribosome. Cell 107, 361-372.
12. Menetret, J.-F., Neuhof, A., Morgan, D.G., Plath, K., Radermacher, M., Rapoport, T.A. & Akey, C.W. (2000) The structure of ribosome-channel complexes engaged in protein translocation. Mol. Cell 6, 1219-1232.
13. Dierks, T., Volkmer, J., Schlenstedt, G., Jung, C., Sandholzer, U., Zachmann, K., Schlotterhose, P., Neifer, K., Schmidt, B. & Zimmermann, R. (1996) A microsomal ATP-binding protein involved in efficient protein transport into the mammalian endoplasmic reticulum. EMBO J. 15, 6932-6942.
14. Tyedmers, J., Lerner, M., Wiedmann, M., Volkmer, J. & Zimmermann, R. (2003) Polypeptide chain binding proteins mediate completion of cotranslational protein translocation into the mammalian endoplasmic reticulum. EMBO Reports 4, 505-510.
15. Meyer, H.-A., Grau, H., Kraft, R., Kostka, S., Prehn, S., Kalies, K.-U. & Hartmann, E. (2000) Mammalian Sec61 is associated with Sec62 and Sec63. J. Biol. Chem. 275, 14550-14557.
16. Dudek, J., Volkmer, J., Bies, C., Guth, S., Müller, A., Lerner, M., Feick, P., Schäfer, K.-H., Morgenstern, E., Hennessy, F., Blatch, G.L., Janoscheck, K., Heim, N., Frien, M., Nastainczyk, W. & Zimmermann, R. (2002) A novel type of cochaperone mediates transmembrane recruitment of DnaK-like chaperones to ribosomes. EMBO J. 21, 2958-2967.
17. Voigt, S., Jungnickel, B., Hartmann, E. & Rapoport, T.A. (1996) Signal-sequence dependent function of the TRAM protein during early phases of protein transport across the ER membrane. J. Cell Biol. 134, 25-35.
18. Fons, R.D., Bogert, B.A. & Hegde, R.S. (2003) Substrate-specific function of the translocon associated protein complex during translocation across the ER membrane. J. Cell Biol. 160, 529-539.
19. Evans, E.A., Gilmore, R. & Blobel, G. (1986) Purification of microsomal signal peptidase as a complex. Proc. Natl Acad. Sci. USA 83, 581-585.
20. Kelleher, D.J., Kreibich, G. & Gilmore, R. (1992) Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd protein. Cell 69, 55-65.
21. Kalies, K.-U., Rapoport, T.A. & Hartmann, E. (1998) The β subunit of the Sec61 complex facilitates cotranslational protein transport and interacts with the signal peptidase during translocation. J. Cell Biol. 141, 887-894.
22. Scheper, W., Thaminy, S., Kais, S., Stagljar, I. & Römisch, K. (2003) Coordination of N-glycosylation and protein translocation across the endoplasmic reticulum membrane by Sssl protein. J. Biol. Chem. 278, 37998-38003.
23. Wiertz, E.J.H., Tortoralla, D., Bogyo, M., Yu, J., Mothes, W., Jones, T.R., Rapoport, T.A. & Ploegh, H.L. (1996) Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature 384, 432-438.
24. Plemper, R.K., Bömler, S., Bordallo, J., Sommer, T. & Wolf, D.H. (1997) Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation. Nature 388, 891-895.
25. Tyedmers, J., Brunke, M., Lechte, M., Sandholzer, U., Dierks, T., Schlotterhose, P., Schmidt, B. & Zimmermann, R. (1996) Efficient folding of firefly luciferase after transport into mammalian microsomes in the absence of luminal chaperones and folding catalysts. J. Biol. Chem. 271, 19509-19513.
26. Watts, C., Wickner, W. & Zimmermann, R. (1983) M13 procoat and pre-immunoglobulin share processing specificity but use different membrane receptor mechanisms. Proc. Natl Acad. Sci. USA 80, 2809-2813.
27. Connolly, T. & Gilmore, R. (1986) Formation of a functional ribosome-membrane junction during translocation requires the participation of a GTP-binding protein. J. Cell Biol. 103, 2253-2261.
28. Murphy, E.C., III, Zheng, T. & Nicchitta, C.V. (1997) Identification of a novel stage of ribosome/nascent chain association with the endoplasmic reticulum membrane. J. Cell Biol. 136, 1213-1226.
29. Schlenstedt, G., Gudmundsson, G.H., Boman, H.G. & Zimmermann, R. (1990) A large presecretory protein translocates both cotranslationally, using signal recognition particle and ribosome, and posttranslationally, without these ribonucleoparticles, when synthesized in the presence of mammalian microsomes. J. Biol. Chem. 265, 13960-13968.
30. Bies, C., Guth, S., Janoschek, K., Nastainczyk, W., Volkmer, J. & Zimmermann, R. (1999) A Scjlp homolog and folding catalysts present in dog pancreas microsomes. Biol. Chem. 380, 1175-1182.
31. Hartmann, E., Wiedmann, M. & Rapoport, T.A. (1989) A membrane component of the endoplasmic reticulum that may be essential for protein translocation. EMBO J. 8, 2225-2229.
32. Wirth, A., Jung, M., Bies, C., Frien, M., Tyedmers, J., Zimmermann, R. & Wagner, R. (2003) The Sec61p complex is a dynamic precursor activated channel. Mol. Cell 12, 261-268.
33. Panzner, S., Dreier, L., Hartmann, E., Kostka, S. & Rapoport, T.A. (1995) Posttranslation protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p. Cell 81, 561-570.
34. Breyton, C., Haase, W., Rapoport, T.A., Kühlbrandt, W. & Collinson, I. (2002) Three-dimensional structure of the bacterial protein translocation complex, SecYEG. Nature 418, 662-665.
35. van den Berg, B., Clemons, W.M., Collinson, I., Modis, Y., Hartmann, E., Harrison, S.C. & Rapoport, T.A. (2004) X-ray structure of a protein-conducting channel. Nature 427, 36-44.
36. Hamman, B.D., Chen, J.C., Johnson, E.E. & Johnson, A.E. (1997) The aqueous pore through the translocon has a diameter of 40-60 A during co-translational protein translocation at the ER membrane. Cell 89, 535-544.