Post-translationally modified S12, absent in transformed breast epithelial cells, is not associated with the 26S proteasome and is induced by proteasome inhibitor

International Journal of Cancer

Volumn 111, Issue 3, 2004, Pages 338-347

  Garrett, H ^a   Thompson, R ^a   Harris, Joseph W ^a   Brody, James P ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California at Irvine   (United States)

Author keywords

19S; Breast cancer; Proteasome; Rpn8; S12

Indexed keywords

26S PROTEASOME; GENE PRODUCT; INITIATION FACTOR 2; INITIATION FACTOR 3; ISOPROTEIN; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN MOV 34; PROTEIN S12; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CELL CYCLE; CELL NUCLEUS; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE INDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOELECTRIC POINT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; BASE SEQUENCE; BREAST; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; DNA PRIMERS; FEMALE; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 3242880721     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20261     Document Type: Article

References (58)

1. Kornitzer D, Ciechanover A. Modes of regulation of ubiquitin-mediated protein degradation. J Cell Physiol 2000;182:1-11.
2. Keyomarsi K, Pardee AB. Redundant cyclin overexpression and gene amplification in breast cancer cells. Proc Natl Acad Sci U S A 1993;90:1112-1116.
3. Hochstrasser M. Ubiquitin-dependent protein degradation. Annu Rev Genet 1996;30:405-439.
4. DeSalle LM, Pagano M. Regulation of the G1 to S transition by the ubiquitin pathway. FEBS Lett 2001;490:179-189.
5. Lavabre-Bertrand T, Henry L, Guiraud I, Carillo S, Bureau JP. [The proteasome and malignant hemopathies]. Morphologie 2000;84:39-43.
6. Lavabre-Bertrand T, Henry L, Carillo S, Guiraud I, Ouali A, Dutaud D, Aubry L, Rossi JF, Bureau JP. Plasma proteasome level is a potential marker in patients with solid tumors and hemopoietic malignancies. Cancer 2001;92:2493-2500.
7. Thompson HG, Harris JW, Wold BJ, Quake SR, Brody JP. Identification and confirmation of a module of coexpressed genes. Genome Res 2002;12:1517-1522.
8. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
9. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Rapp BA, Wheeler DL. GenBank. Nucleic Acids Res 2002;30:17-20.
10. O'Farrell PH. High resolution two-dimensional electrophoresis of proteins. J Biol Chem 1975;250:4007-4021.
11. Apweiler R, Attwood TK, Bairoch A, Bateman A, Birney E, Biswas M, Bucher P, Cerutti L, Corpet F, Croning MD, Durbin R, Falquet L, et al. The InterPro database, an integrated documentation resource for protein families, domains and functional sites. Nucleic Acids Res 2001;29:37-40.
12. Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW. Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly. J Biol Chem 1997;272:27042-27052.
13. Blom N, Gammeltoft S, Brunak S. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J Mol Biol 1999;294:1351-1362.
14. Nakai K, Kanehisa M. A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics 1992;14:897-911.
15. Gupta R, Brunak S. Prediction of glycosylation across the human proteome and the correlation to protein function. Pac Symp Biocomput 2002:310-322.
16. Yang Y, Fruh K, Ahn K, Peterson PA. In vivo assembly of the proteasomal complexes, implications for antigen processing. J Biol Chem 1995;270:27687- 27694.
17. Kuehn L, Dahlmann B. Proteasome activator PA28 and its interaction with 20 S proteasomes. Arch Biochem Biophys 1996;329:87-96.
18. Brooks P, Fuertes G, Murray RZ, Bose S, Knecht E, Rechsteiner MC, Hendil KB, Tanaka K, Dyson J, Rivett J. Subcellular localization of proteasomes and their regulatory complexes in mammalian cells. Biochem J 2000;346 Pt 1:155-161.
19. Chu-Ping M, Vu JH, Proske RJ, Slaughter CA, DeMartino GN. Identification, purification, and characterization of a high molecular weight, ATP-dependent activator (PA700) of the 20 S proteasome. J Biol Chem 1994;269:3539-3547.
20. Richmond C, Gorbea C, Rechsteiner M. Specific interactions between ATPase subunits of the 26 S protease. J Biol Chem 1997;272:13403-13411.
21. Glickman MH, Rubin DM, Coux O, Wefes I, Pfeifer G, Cjeka Z, Baumeister W, Fried VA, Finley D. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and elF3. Cell 1998;94:615-623.
22. Confalonieri F, Duguet M. A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
23. Saeki Y, Toh-e A, Yokosawa H. Rapid isolation and characterization of the yeast proteasome regulatory complex. Biochem Biophys Res Commun 2000;273:509-515.
24. Bose S, Brooks P, Mason GG, Rivett AJ. gamma-Interferon decreases the level of 26 S proteasomes and changes the pattern of phosphorylation. Biochem J 2001;353:291-297.
25. Tanahashi N, Murakami Y, Minami Y, Shimbara N, Hendil KB, Tanaka K. Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis. J Biol Chem 2000;275:14336-14345.
26. Stohwasser R, Giesebrecht J, Kraft R, Muller EC, Hausler KG, Kettenmann H, Hanisch UK, Kloetzel PM. Biochemical analysis of proteasomes from mouse microglia: induction of immunoproteasomes by interferon-gamma and lipopolysaccharide. Glia 2000;29:355-365.
27. Enenkel C, Lehmann A, Kloetzel PM. Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast. Embo J 1998;17:6144-6154.
28. Rivett AJ, Bose S, Brooks P, Broadfoot KI. Regulation of proteasome complexes by gamma-interferon and phosphorylation. Biochimie 2001;83:363-366.
29. Mason GG, Murray RZ, Pappin D, Rivett AJ. Phosphorylation of ATPase subunits of the 26S proteasome. FEBS Lett 1998;430:269-274.
30. Ferdous A, Gonzalez F, Sun L, Kodadek T, Johnston SA. The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II. Mol Cell 2001;7:981-991.
31. Gonzalez F, Delahodde A, Kodadek T, Johnston SA. Recruitment of a 19S proteasome subcomplex to an activated promoter. Science 2002;296:548-550.
32. Ferdous A, Kodadek T, Johnston SA. A Nonproteolytic Function of the 19S Regulatory Subunit of the 26S Proteasome Is Required for Efficient Activated Transcription by Human RNA Polymerase II. Biochemistry 2002;41:12798-12805.
33. Tanaka K, Kasahara M. The MHC class I ligand-generating system: roles of immunoproteasomes and the interferon-gamma-inducible proteasome activator PA28. Immunol Rev 1998;163:161-176.
34. Reits EA, Benham AM, Plougastel B, Neefjes J, Trowsdale J. Dynamics of proteasome distribution in living cells. Embo J 1997;16:6087-6094.
35. Rivett AJ. Intracellular distribution of proteasomes. Curr Opin Immunol 1998;10:110-114.
36. Russell SJ. Steger KA, Johnston SA. Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 1999;274:21943-21952.
37. Yanagi S, Shimbara N, Tamura T. Tissue and cell distribution of a mammalian proteasomal ATPase, MSS1, and its complex formation with the basal transcription factors. Biochem Biophys Res Commun 2000;279:568-573.
38. Dubiel W, Ferrell K, Dumdey R, Standera S, Prehn S, Rechsteiner M. Molecular cloning and expression of subunit 12: a non-MCP and non-ATPase subunit of the 26 S protease. FEBS Lett 1995;363:97-100.
39. Realini C, Rogers SW, Rechsteiner M. KEKE motifs. Proposed roles in protein-protein association and presentation of peptides by MHC class I receptors. FEBS Lett 1994;348:109-113.
40. Shimanuki M, Saka Y, Yanagida M, Toda T. A novel essential fission yeast gene pad1 + positively regulates pap1(+)-dependent transcription and is implicated in the maintenance of chromosome structure. J Cell Sci 1995;108:569-579.
41. Fu H, Reis N, Lee Y, Glickman MH, Vierstra RD. Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome. Embo J 2001;20:7096-7107.
42. Seeger M, Kraft R, Ferrell K, Bech-Otschir D, Dumdey R, Schade R, Gordon C, Naumann M, Dubiel W. A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits. Faseb J 1998;12:469-478.
43. Braun BC, Glickman M, Kraft R, Dahlmann B, Kloetzel PM, Finley D, Schmidt M. The base of the proteasome regulatory particle exhibits chaperone-like activity. Nat Cell Biol 1999;1:221-226.
44. An B, Goldfarb RH, Siman R, Dou QP. Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts. Cell Death Differ 1998;5:1062-1075.
45. Pasquini LA, Besio Moreno M, Adamo AM, Pasquini JM, Soto EF. Lactacystin, a specific inhibitor of the proteasome, induces apoptosis and activates caspase-3 in cultured cerebellar granule cells. J Neurosci Res 2000;59:601-611.
46. Fan XM, Wong BC, Wang WP, Zhou XM, Cho CH, Yuen ST, Leung SY, Lin MC, Kung HF, Lam SK. Inhibition of proteasome function induced apoptosis in gastric cancer. Int J Cancer 2001;93:481-488.
47. Kuusisto E, Suuronen T, Salminen A. Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. Biochem Biophys Res Commun 2001;280:223-228.
48. Thompson HGR, Harris JW, Wold BJ, Lin F, Brody JP. p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells. Oncogene 2003;22:2322-2333.
49. Kang Z, Pirskanen A, Janne OA, Palvimo JJ. Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex. J Biol Chem 2002;277:48366-48371.
50. Reinhardt A, Hubbard T. Using neural networks for prediction of the subcellular location of proteins. Nucleic Acids Res 1998;26:2230-2236.
51. Horton P, Nakai K. Better prediction of protein cellular localization sites with the k nearest neighbors classifier. Proc Int Conf Intell Syst Mol Biol 1997;5:147-152.
52. Aravind L, Ponting CP. Homologues of 26S proteasome subunits are regulators of transcription and translation. Protein Sci 1998;7:1250-1254.
53. Ferrell K, Wilkinson CR, Dubiel W, Gordon C. Regulatory subunit interactions of the 26S proteasome, a complex problem. Trends Biochem Sci 2000;25:83-88.
54. Whitehouse AS, Tisdale MJ. Downregulation of ubiquitin-dependent proteolysis by eicosapentaenoic acid in acute starvation. Biochem Biophys Res Commun 2001;285:598-602.
55. Mason GG, Hendil KB, Rivett AJ. Phosphorylation of proteasomes in mammalian cells. Identification of two phosphorylated subunits and the effect of phosphorylation on activity. Eur J Biochem 1996;238:453-462.
56. Cagney G, Uetz P, Fields S. Two-hybrid analysis of the Saccharomyces cerevisiae 26S proteasome. Physiol Genomics 2001;7:27-34.
57. Davy A, Bello P, Thierry-Mieg N, Vaglio P, Hitti J, Doucette-Stamm L, Thierry-Mieg D, Reboul J, Boulton S, Walhout AJ, Coux O, Vidal M. A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome. EMBO Rep 2001;2:821-828.
58. Chai Y, Koppenhafer SL, Shoesmith SJ, Perez MK, Paulson HL. Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro. Hum Mol Genet 1999;8:673-682.