Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome

EMBO Journal

Volumn 20, Issue 24, 2001, Pages 7096-7107

  Fu, Hongyong ^a   Reis, Noa ^b   Lee, Yenfen ^a   Glickman, Michael H ^b   Vierstra, Richard D ^c  

^a INSTITUTE OF PLANT AND MICROBIAL BIOLOGY   (Taiwan)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

26S proteasome; COP9 signalosome; Proteolysis; Ubiquitin; Yeast two hybrid

Indexed keywords

26S PROTEASOME; COP9 SIGNALOSOME; PROTEASOME; PROTEIN SUBUNIT; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ENZYME SPECIFICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; SACCHAROMYCES CEREVISIAE; TWO HYBRID SYSTEM;

ARABIDOPSIS PROTEINS; ASPARTIC ACID; CYSTEINE ENDOPEPTIDASES; HYDROLYSIS; MULTIENZYME COMPLEXES; MULTIPROTEIN COMPLEXES; MUTAGENESIS; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEINS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY;

ARABIDOPSIS; EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037126632     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.24.7096     Document Type: Article

References (35)

1. Homologues of 26S proteasome subunits are regulators of transcription and translation
2. Functional characterization of rpn3 uncovers a distinct 19S proteasomal subunit requirement for ubiquitin-dependent proteolysis of cell cycle regulatory proteins in budding yeast
3. COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system
4. A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome
5. Unified nomenclature for the COP9 signalosome and its subunits: An essential regulator of development
6. Crystal structure of the von Willebrand factor A1 domain and implications for the binding of platelet glycoprotein Ib
7. Regulatory subunit interactions of the 26S proteasome, a complex problem
8. Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26S proteasome subunit Mcb1
9. Multiubiquitin chain binding subunit MCB1 (RPN10) of the 26S proteasome is essential for developmental progression in Physcomitrella patens
10. Getting in and out of the proteasome
11. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9/signalosome and eIF3
12. Mapping subunit contacts in the regulatory complex of the 26S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7
13. Quaternary structure of the ATPase complex of human 26S proteasomes determined by chemical cross-linking
14. The PCI domain: A common theme in three multi-protein complexes
15. A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal degradation systems
16. A comprehensive two-hybrid analysis to explore the yeast protein interactome
17. Ubiquitin as a degradation signal
18. A proteolytic pathway that recognizes ubiquitin as a degradation signal
19. Electron microscopy and subunit-subunit interaction studies reveal a first architecture of COP9 signalosome
20. Arabidopsis FUSCA5 encodes a novel phosphoprotein that is a component of the COP9 complex
21. PCI complexes: Pretty complex interactions in diverse signaling pathways
22. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome
23. Identification of amino acid residues essential for von Willebrand factor binding to platelet glycoprotein Ib. Charged-to-alanine scanning mutagenesis of the A1 domain of human von Willebrand factor
24. The cellular level of PR500, a protein complex related to the 19S regulatory particle of the proteasome, is regulated in response to stresses in plants
25. Protein-protein interactions: Methods for detection and analysis
26. Specific interactions between ATPase subunits of the 26S proteasome
27. Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome
28. Rapid isolation and characterization of the yeast proteasome regulatory complex
29. Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26S proteasome
30. The subunit of the COP9 signalsome suppresses gene expression through its N-terminal domain and incorporates into the complex through the PCI domain
31. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
32. The multiubiquitin chain binding protein Mcbl is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover
33. The 26S proteasome: A molecular machine designed for controlled proteolysis
34. 26S proteasome structure revealed by three-dimensional electron microscopy
35. Analysis of a gene encoding Rpn10 of the fission yeast proteasome reveals that the polyubiquitin-binding site of this subunit is essential when Rpn12/Mts3 activity is compromised