Cohesin relocation from sites of chromosomal loading to places of convergent transcription

Nature

Volumn 430, Issue 6999, 2004, Pages 573-578

  Lengronne, Armelle ^a   Katou, Yuki ^b   Mori, Saori ^c,d   Yokabayashi, Shihori ^e   Kelly, Gavin P ^a   Ito, Takehiko ^f   Watanabe, Yoshinori ^e,g   Shirahige, Katsuhiko ^b,c   Uhlmann, Frank ^a  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^b RIKEN YOKOHAMA INSTITUTE   (Japan)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^d YOKOHAMA CITY UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f MITSUBISHI RESEARCH INSTITUTE   (Japan)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMES; DNA; PROTEINS; SYNTHESIS (CHEMICAL); YEAST;

EUKARYOTIC CHROMOSOMES; FISSION YEAST; MITOTIC CHROMOSOMES; YEAST CHROMOSOMES;

GENETIC ENGINEERING;

COHESIN; DNA; CELL CYCLE PROTEIN; COHESINS; FUNGAL PROTEIN; NONHISTONE PROTEIN; NUCLEAR PROTEIN; SPACER DNA;

BIOLOGY;

ARTICLE; CHROMATID; CHROMOSOME; DNA REPLICATION; DNA SEQUENCE; DNA STRAND; EUKARYOTIC CELL; GENETIC TRANSCRIPTION; IN VIVO STUDY; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; YEAST; CHROMOSOME SEGREGATION; CYTOLOGY; FUNGAL GENE; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES;

EUKARYOTA; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE;

CELL CYCLE PROTEINS; CHROMATIDS; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME SEGREGATION; CHROMOSOMES, FUNGAL; CONSERVED SEQUENCE; DNA, INTERGENIC; FUNGAL PROTEINS; GENES, FUNGAL; NUCLEAR PROTEINS; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; TRANSCRIPTION, GENETIC;

EID: 3242880374     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02742     Document Type: Article

References (30)

1. Michaelis, C., Ciosk, R. & Nasmyth, K. Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids. Cell 91, 35-45 (1997).
2. Guacci, V., Koshland, D. & Strunnikov, A. A direct link between sister chromatid cohesion and chromosome condensation revealed through analysis of MCD1 in S. cerevisiae. Cell 91, 47-57 (1997).
3. Losada, A., Hirano, M. & Hirano, T. Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev. 12, 1986-1997 (1998).
4. Tomonaga, T. et al. Characterization of fission yeast cohesin: Essential anaphase proteolysis of Rad21 phosphorylated in the S phase. Genes Dev. 14, 2757-2770 (2000).
5. Tanaka, T., Fuchs, J., Loidl, J. & Nasmyth, K. Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation. Nature Cell Biol. 2, 492-499 (2000).
6. Uhlmann, F. Chromosome cohesion and separation: From men and molecules. Curr. Biol. 13, R104-R114 (2003).
7. Haering, C. H., Löwe, J., Hochwagen, A. & Nasmyth, K. Molecular architecture of SMC proteins and the yeast cohesin complex. Mol. Cell 9, 773-788 (2002).
8. Ciosk, R. et al. Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol. Cell 5, 1-20 (2000).
9. Blat, Y. & Kleckner, N. Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. Cell 98, 249-259 (1999).
10. Tanaka, T., Cosma, M. P., Wirth, K. & Nasmyth, K. Identification of cohesin association sites at centromeres and along chromosome arms. Cell 98, 847-858 (1999).
11. Megee, P. C. & Koshland, D. A functional assay for centromere-associated sister chromatid cohesion. Science 285, 254-257 (1999).
12. Laloraya, S., Guacci, V. & Koshland, D. Chromosomal addresses of the cohesin component Mcd1p. J. Cell Biol. 151, 1047-1056 (2000).
13. Nonaka, N. et al. Recruitment of cohesin to heterochromatic regions by Swi6/HPI in fission yeast. Nature Cell Biol. 4, 89-93 (2001).
14. Bernard, P. et al. Requirement of heterochromatin for cohesion at centromeres. Science 294, 2539-2542 (2001).
15. Hakimi, M.-A. et al. A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature 418, 994-997 (2002).
16. Katou, Y. et al. S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex. Nature 424, 1078-1083 (2003).
17. Filipski, J. & Mucha, M. Structure, function and DNA composition of Saccharomyces cerevisiae chromatin loops. Gene 300, 63-68 (2002).
18. Chu, S. et al. The transcriptional program of sporulation in budding yeast. Science 282, 699-705 (1998).
19. Gasch, A. P. et al. Genomic expression programs in the response of yeast cells to environmental changes. Mol. Biol. Cell 11, 4241-4257 (2000).
20. Toth, A. et al. Yeast cohesin complex requires a conserved protein, Eco1p (Ctf7), to establish cohesion between sister chromatids during DNA replication. Genes Dev. 13, 320-333 (1999).
21. Arumugam, P. et al. ATP hydrolysis is required for cohesin's association with chromosomes. Curr. Biol. 13, 1941-1953 (2003).
22. Sjögren, C. & Nasmyth, K. Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. Curr. Biol. 11, 991-995 (2001).
23. Jacq, C. et al. The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Nature 387 (suppl), 75-78 (1997).
24. Donze, D., Adams, C. R., Rine, J. & Kamakaka, R. T. The boundaries of the silenced HMR domain in Saccharomyces cerevisiae. Genes Dev. 13, 698-708 (1999).
25. Cohen, B. A., Mitra, R. D., Hughes, J. D. & Church, G. M. A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression. Nature Genet. 26, 183-186 (2000).
26. Weitzer, S., Lehane, C. & Uhlmann, F. A model for ATP hydrolysis-dependent binding of cohesin to DNA. Curr. Biol. 13, 1930-1940 (2003).
27. Toyoda, Y. et al. Requirement of chromatid cohesion proteins Rad21/Scc1 and Mis4/Scc2 for normal spindle-kinetocore interaction in fission yeast. Curr. Biol. 12, 347-358 (2002).
28. Waizenegger, I. C., Hauf, S., Meinke, A. & Peters, J.-M. Two distinct pathways remove mammalian cohesin complexes from chromosome arms in prophase and from centromeres in anaphase. Cell 103, 399-410 (2000).
29. Reid, R. J. D., Sunjevaric, I., Kedacche, M. & Rothstein, R. Efficient PCR-based gene disruption in Saccharomyces strains using intergenic primers. Yeast 19, 319-328 (2002).
30. Ohta, K. et al. Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells. Proc. Natl Acad. Sci. USA 95, 645-651 (1998).