The boundaries of the silenced HMR domain in Saccharomyces cerevisiae

Genes and Development

Volumn 13, Issue 6, 1999, Pages 698-708

  Donze, David ^a   Adams, Christopher R ^a   Rine, Jasper ^b   Kamakaka, Rohinton T ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Boundary elements; Heterochromatin; HMR; S. cerevisiae; Silencing

Indexed keywords

ARTICLE; CHROMATIN STRUCTURE; GENE DELETION; GENE LOCUS; HETEROCHROMATIN; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SILENCER GENE; TRANSCRIPTION REGULATION;

EUKARYOTA; FUNGI; MYXOGASTRIA; SACCHAROMYCES CEREVISIAE;

EID: 0033558878     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.6.698     Document Type: Article

References (32)

1. Brand, A.H., L. Breeden, J. Abraham, R. Sternglanz, and K. Nasmyth. 1985. Characterization of a 'silencer' in yeast: A DNA sequence with properties opposite to those of a transcriptional enhancer. Cell 41: 41-48.
2. Chuang, P.T., D.G. Albertson, and B.J. Meyer. 1994. DPY-27: A chromosome condensation protein homolog that regulates C. elcgans dosage compensation through association with the X chromosome. Cell 79: 459-474.
3. Corces, V.G. and P.K. Geyer. 1991. Interactions of retrotransposons with the host genome: The case of the gypsy element of Drosophila. Trends Genet. 7: 86-90.
4. Eisenmann, D.M., K.M. Arndt, S.L. Ricupero, J.W. Rooney, and F. Winston. 1992. SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae. Genes & Dev. 6: 1319-1331.
5. Eisenmann, D.M., C. Chapon, S.M. Roberts, C. Dollard, and F. Winston. 1994. The Saccharomyces cerevisiae SPT8 gene encodes a very acidic protein that is functionally related to SPT3 and TATA-binding protein. Genetics 137: 647-657.
6. Elgin, S.C.R. 1996. Heterochromatin and gene regulation in Drosophila. Curr. Opin. Genet. Dev. 6: 193-202.
7. Gasser, S.M. and U.K. Laemmli. 1987. A glimpse at chromosomal order. Trends Genet. 3: 16-22.
8. Gdula, D.A., T.I. Gerasimova, and V.G. Corces. 1996. Genetic and molecular analysis of the gypsy chromatin insulator of Drosophila. Proc. Natl. Acad. Sci. 93: 9378-9383.
9. Geyer, P.K. and V.G. Corces. 1992. DNA position-specific repression of transcription by a Drosophila zinc finger protein. Genes & Dev. 6: 1865-1873.
10. Gottschling, D.E., O.M. Aparicio, B.L. Billington, and V.A. Zakian. 1990. Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63: 751-762.
11. Hirano, T. and T.J. Mitchison. 1994. A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro. Cell 79: 449-458.
12. Hull, M.W., J. Erickson, M. Johnston, and D.R. Engelke. 1994. tRNA genes as transcriptional represser elements. Mol. Cell. Biol. 14: 1266-1277.
13. Kamakaka, R.T. 1997. Silencers and locus control regions: Opposite sides of the same coin. Trends Biochem. Sci. 22: 124-128.
14. Kamakaka, R.T. and J. Rine. 1998. Sir- and silencer-independent disruption of silencing in Saccharomyces by sas10p. Genetics 149: 903-914.
15. Kellum, R. and S. Elgin. 1998. Chromatin boundaries: Punctuating the genome. Curr. Biol. 8: 521-524.
16. Kellum, R. and P. Schedl. 1991. A position-effect assay for boundaries of higher order chromosomal domains. Cell 64: 941-950.
17. _. 1992. A group of scs elements function as domain boundaries in an enhancer-blocking assay. Mol. Cell. Biol. 12: 2424-2431.
18. Koshland, D. and A. Strunnikov. 1996. Mitotic chromosome condensation. Annu. Rev. Cell Dev. Biol 12: 305-333.
19. Laloux, I., E. Jacobs, and E. Dubois. 1994. Involvement of SRE element of Ty1 transposon in TEC1-dependent transcriptional activation. Nucleic Acids Res. 22: 999-1005.
20. Loo, S. and J. Rine. 1994. Silencers and domains of generalized repression. Science 264: 1768-1771.
21. _. 1995. Silencing and heritable domains of gene expression. Annu. Rev. Cell Dev. Biol. 11: 519-548.
22. Mastrangelo, M.F., K.G. Weinstock, B.K. Shafer, A.-M. Hedge, D.J. Garfinkel, and J.N. Strathern. 1992. Disruption of a silencer domain by a retrotransposon. Genetics 131: 519-529.
23. Nasmyth, K.A. 1982. The regulation of yeast mating-type chromatin structure by SIR: An action at a distance affecting both transcription and transposition. Cell 30: 567-578.
24. Renauld, H., O.M. Aparicio, P.D. Zierath, B.L. Billington, S.K. Chhablani, and D.E. Gottschling. 1993. Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes & Dev. 7: 1133-1145.
25. Roseman, R.R., V. Pirrotta, and P.K. Geyer. 1993. The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects. EMBO J. 12: 435-442.
26. Saitoh, Y. and U.K. Laemmli. 1993. From the chromosomal loops and the scaffold to the classic bands of metaphase chromosomes. Cold Spring Harbor Symp. Quant. Biol. 58: 755-765.
27. Schnell, R. and J. Rine. 1986. A position effect on the expresion of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 6: 494-501.
28. Singh, J. and A.J.S. Klar. 1992. Active genes in budding yeast display enhanced in vivo accessibility to foreign DNA methylases: A novel in vivo probe for chromatin structure of yeast. Genes & Dev. 6: 186-196.
29. Swanson, M.S. and F. Winston. 1992. SPT4, SPT5 and SPT6 interactions: Effects on transcription and viability in Saccharomyces cerevisiae. Genetics 132: 325-336.
30. Turkel, S., X.-B. Liao, and P.J. Farabaugh. 1997. GCR1-dependent transcriptional activation of yeast retrotransposon Ty2-917. Yeast 13: 917-930.
31. Voytas, D.F. and J.D. Boeke. 1993. Yeast retrotransposons and tRNAs. Trends Genet. 9: 421-427.
32. Widom, J. 1998. Structure, dynamics, and function of chromatin in vitro. Annu. Rev. Biophys. Biomol. Struct. 27: 285-327.