Immunodominance of a low-affinity major histocompatibility complex- binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire

Journal of Clinical Investigation

Volumn 100, Issue 2, 1997, Pages 339-349

  Muraro, Paolo A ^a,b   Vergelli, Marco ^a   Kalbus, Matthias ^c   Banks, Darhlene E ^a   Nagle, James W ^a   Tranquill, Laura R ^a   Nepom, Gerald T ^d   Biddison, William E ^a   McFarland, Henry F ^a   Martin, Roland ^a,c  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY OF CHIETI   (Italy)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d BENAROYA RESEARCH INSTITUTE   (United States)

Author keywords

Autoantigens; Autoimmune diseases; CD4 positive T lymphocytes; Complementarity determining region; Multiple sclerosis

Indexed keywords

EPITOPE; HLA DR4 ANTIGEN; MYELIN BASIC PROTEIN; T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; RECEPTOR AFFINITY; T LYMPHOCYTE;

EID: 0030749517     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119539     Document Type: Article

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