Evidence for genetic basis of multiple sclerosis

Lancet

Volumn 347, Issue 9017, 1996, Pages 1728-1730

  Sadovnick, A D ^a   Ebers, G C ^b   Dyment, D A ^a   Risch, N J ^c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ENVIRONMENTAL FACTOR; GENETIC SUSCEPTIBILITY; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MONOZYGOTIC TWINS; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; RISK;

EID: 0030007661     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(96)90807-7     Document Type: Article

References (30)

1. Sadovnick AD, Ebers GC. Epidemiology of multiple sclerosis: a critical overview. Can J Neurol Sci 1993; 20: 17-29.
2. Ebers GC, Sadovnick AD. Genetics of multiple sclerosis: a critical overview. J Neuroimmunol 1994; 54: 117-22.
3. Kurtzke JF. Epidemiological evidence for multiple sclerosis as an infection. Clin Microbiol Rev 1993; 6: 382-427.
4. Ebers GC, Bulman DE, Sadovnick AD, et al. A population-based twin study in multiple sclerosis. N Engl J Med 1986; 315: 1638-42.
5. Sadovnick AD, Armstrong H, Rice GPA, et al. A population-based twin study of multiple sclerosis in twins: update. Ann Neurol 1993; 33: 281-85.
6. Mumford CJ, Wood NW, Kellar-Wood H, Thorpe JW, Miller DH, Compston DA. Neurology 1994; 44: 11-15.
7. Dean G. Annual incidence, prevalence and mortality of multiple sclerosis in white South African-born and in white immigrants to South Africa. BMJ 1967; ii: 724-30.
8. Alter M, Hapern L, Kurland LT, et al. Multiple sclerosis in Israel: prevalence among migrants and native inhabitants. Arch Neurol 1962; 7: 253-63.
9. Schuckit M, Goodwin DW, Winokur G. In: Roff M, Robins IN, Pollack M, eds. Life history research in psychopathology. Minneapolis: University of Minnesota Press, 1972: vol 2, 120-27.
10. McGue M, Gottesman II, Rao DC. The analysis of schizophrenia family data. Behavioural Genet 1987; 16: 75-87.
11. Roberts DF, Billewicz WZ, McGregor IA. Heritability of stature in a West African population. Ann Hum Genet 1978; 42: 15-24.
12. Myrianthopoulos NC. In: Morton NE, Chung CS, eds. Genetic epidemiology. New York: Academic Press, 1978: 363-79.
13. Tierney C, Merikangas KR, Risch N. Feasibility of half-sibling designs for detecting a genetic component to a disease. Genet Epidemiol 1994; 11: 523-38.
14. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983; 13: 227-31.
15. Sadovnick AD, Baird PA, Ward RH. Multiple sclerosis: updated risks for relatives. Am J Med Genet 1988; 29: 533-41.
16. Ebers GC, Sadovnick AD, Risch NJ and the Canadian Collaborative Study Group. Familial aggregation in multiple sclerosis is genetic. Nature 1995; 377: 150-51.
17. Risch N. Estimating morbidity risks with variable age of onset: review of methods and a maximum likelihood approach. Biometrics 1983; 39: 929-39.
18. Gaudet JPC, Hashimoto L, Sadovnick AD, Ebers GC. A study of birth order and multiple sclerosis in multiplex families. Neuroepidemiology 1995; 14: 188-92.
19. Gaudet JPC, Hashimoto L, Sadovnick AD, Ebers GC. Is multiple sclerosis caused by late childhood infection: a case-control study of birth order in sporadic cases of multiple sclerosis. Acta Neurol Scand 1995; 91: 19-21.
20. Finelli PF. Conjugal multiple sclerosis: a clinical and laboratory study. Neurology 1991; 41: 1320-21.
21. Kaufman MD. Conjugal multiple sclerosis. Neurology 1992; 42: 1644-45.
22. Frederikson S, Michelsberg J, Hillert J, et al. Conjugal multiple sclerosis: immunogenetic characterization and analysis of T- and B-cell reactivity to myelin proteins. Neurology 1992; 42: 577-82.
23. Schapira K, Poskanzer DC, Miller H. Familial and conjugal multiple sclerosis. Brain 1963; 86: 315-32.
24. Bulman DE, Sadovnick AD, Ebers GC. Age of onset in siblings concordant for multiple sclerosis. Brain 1991; 114: 937-50.
25. Hader WJ, Feasby TE, Noseworthy JH, Rice GPA, Ebers GC. Multiple sclerosis in Canadian Native People. Neurology 1985; 35 (suppl 1): 300.
26. Detels R, Visscher BR, Malmgren RM, et al. Evidence for lower susceptibility to multiple sclerosis in Japanese Americans. Am J Epidemiol 1977; 105: 303-10.
27. Gronning M, Mellgren SI. Multiple sclerosis in the two northernmost counties of Norway. Acta Neurol Scand 1985; 72: 321-27.
28. Sadovnick AD, Ebers GC. Genetic factors in the pathogenesis of MS. Int MS J 1994; 1: 17-24.
29. Sadovnick AD, Ebers GC and the Canadian Collaborative Study Group. Basic, clinical and genetic epidemiology of MS. J Neuroimmunol (in press).
30. Hammond SR, McLeod JG, Millingen KS, et al. The epidemiology of multiple sclerosis in three Australian cities: Perth, Newcastle and Hobart. Brain 1988; 111: 1-25.