Ultrastructural evaluation of activated forms of microglia in human brain in selected neurological diseases (SSPE, Wilson's disease and Alzheimer's disease)

Folia Neuropathologica

Volumn 42, Issue 2, 2004, Pages 81-91

  Lewandowska, Eliza ^a   Wierzba Bobrowicz, Teresa ^a   Kosno Kruszewska, Elzbieta ^a   Lechowicz, Waldemar ^a   Schmidt Sidor, Bogna ^a   Szpak, Grazyna M ^a   Bertrand, Ewa ^a   Pasennik, Elzbieta ^a   Gwiazda, Elzbieta ^a  

^a INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

Author keywords

Activated rod; Alzheimer's disease; Ramified and amoeboid microglia; Subacute sclerosing panencephalitis; Ultrastructure; Wilson's disease

Indexed keywords

AMYLOID;

ADULT; AGED; ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL NUCLEUS INCLUSION BODY; CELL NUCLEUS MEMBRANE; CELL PROLIFERATION; CELL ULTRASTRUCTURE; CENTRIOLE; CHROMOSOME; CONTROLLED STUDY; CYTOPLASM; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LAMELLAR BODY; LANGERHANS CELL; MALE; MEASLES VIRUS; MICROGLIA; MITOSIS; NEUROLOGIC DISEASE; PATHOGENESIS; ROUGH ENDOPLASMIC RETICULUM; SENILE PLAQUE; SUBACUTE SCLEROSING PANENCEPHALITIS; VIRUS NUCLEOCAPSID; WILSON DISEASE;

EID: 3242785724     PISSN: 16414640     EISSN: 1509572X     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Ando T, Kawabe T, Ohara H, Ducommun B, Itoh M, Okamoto T (2001) Involvement of the interaction between p21 and proliferating cell nuclear antigen for the maintenance of G2/M arrest after DNA damage. J Biol Chem, 176: 42971-42977.
2. Anlar S, Soylemezoglu F, Elibot B, Dalkara T, Aysun S, Kose G, Belen D, Yalaz K (1999) Apoptosis in brain biopsies of subacute sclerosing panencephalitis patients. Neuropediatrics, 30:239-242.
3. Aschner M, Allen JW, Kimelberg HK, LoPachin RM, Streit WJ (1999) Glial cells in neurotixicity development. Ann Rev Pharmacol Toxico, 39: 151-173.
4. Benveniste EN, Nguyen VT, O'Keefe GM (2001) Immunological aspects of microglia: relevance to Alzheimer's disease. Neurochem Int, 5-6: 381-391.
5. Bernhardi R, Ramirez G (2001) Microglia-astrocyte interaction in Alzheimer's disease: friends or foes for the nervous system? Biol Res, 2: 123-128.
6. Brasch K, Ochs RI (1992) Nuclear bodies (NBs): a newly "rediscovered" organelle. Exp Cell Res, 202: 211-223.
7. Bruce AJ, Boling W, Kindly MS, Peschon J, Kraemer PJ, Carpenter MK, Holtsberg FW, Mattson MP (1996) Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF-receptors. Nature Med, 2: 788-794.
8. Bruce-Keller AJ (1999) Microglial-neuronal interactions in synaptic damage and recovery. J Neurosci Res, 58: 191-201.
9. Carmo-Fonseca M, Ferreira J, Lamond AI (1993) Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis-evidence that the coiled body is a kinetic nuclear structure. J Cell Biol, 120: 841-852.
10. Cross AK, Woodroofe MN (2001) Immunoregulation of microglial functional properties. Microsc Res Tech, 54: 10-17.
11. DiCarlo G, Wilcock D, Henderson D, Gordon M, Morgan D (2001) Intra hippocampal LPS injections reduce Abeta load in APP + + PS1 transgenic mice. Neurobiol Aging, 6: 1007-1012.
12. Dumont A, Robert A (1971) Ultrastructure of complex nuclear bodies produced experimentally in hamster peritoneal macrophages. J Ultrastruc Res, 36: 483-492.
13. Frackowiak J, Wiśniewski HM, Wegiel J, Merz GS, Wang KC (1992) Ultrastructure of microglia that phagocytose amyloid and the microglia that produce β-amyloid fibrils. Acta Neuropathol (Berl), 84: 225-233.
14. Giulian D (1987) Ameboid microglia as effectors of inflammation in the central nervous system. J Neurosci Res, 18: 155-171.
15. Harris-White ME, Chu T, Miller S.A., Simmons M, Teter B, Nash D, Cole GM, Frautschy SA (2001) Estrogen (E2) and glucoccorticoid (Gc) effects on microglia and A beta clearance in vitro and vivo. Neurochem Int, 5-6: 435-448.
16. Hofman FM, Hinton DR, Baemayr J, Weil M, Merrill JE (1991) Lymphokines and immunoregulatory molecules in subacute sclerosing panencephalitis. Clin Immunol Immunopathol, 58:331-342.
17. Kreutzberg GW (1996) Microglia: a sensor for pathological events in the CNS.Trends Neurosci, 19: 312-318.
18. Lewandowska E, Bertrand E, Kulczycki J, Lipczyńska-Łojkowska W, Lechowicz W, Stankiewicz J (1999) Microglia and neuritic plaques in familial Alzheimer's disease induced by a new mutation of presenilin-1 gene. An ultrastructural study. Folia Neuropathol, 4: 243-246.
19. Lewandowska E, Szpak GM, Lechowicz W, Pasennik E, Sobczyk W (2001) Ultrastructural changes in neuronal and glial cells in subacute sclerosing panencephalitis: correlation with disease duration. Folia Neuropathol, 39, 3: 193-202.
20. Liu J, Hebert MD, Ye Y, Templeton DJ, Kung H, Matera AG (2000) Cell Cycle-dependent localization of the CDK-cyclin E complex in Cajal (coiled) bodies. J Cell Sci, 113: 1543-1552.
21. Lynch WP, Czub S, McAtee FJ, Hayes SF, Portis JL (1991) Murine retrovirus-induced spongiform encephalopathy: productive infection of microglia and cerebellar neurons in accelerated CNS disease. Neuron, 7: 365-379.
22. Malatesta M, Zancanaro C, Martin TE, Chan EK, Almaric EK, Luhrmann R, Vogel P, Facan S (1994) Is the coiled body involved in nucleolar functions. Exp Cell Res, 211: 415-419.
23. Matera AG (1999) Nuclear bodies: multifaceted subdomains of the interchromatin space. Trends Cell Biol, 9: 302-309.
24. McQuaid S, McMahon J, Herron B, Cosby SL (1997) Apoptosis in measles virus-infected human nervous system tissues. Neuropathol Appl Neurobiol, 23: 218-224.
25. Meda L, Baron P, Scarlato G (2001) Gial activation in Alzheimer's disease: the role of Abeta and its associated proteins. Neurobiol-Aging, 6: 885-893.
26. Morita K (1998) Analysis of HAM rat disease with HTLV-I infection, an animal model for HAM/TSP in human-immunohistochemical, immuno-electron microscopic and flow cytometrical analyses of microglia/macrofages in the affected spinal cord. Hokkaido-Igaku-Zasshi, 3: 253-274.
27. Nagano I, Nakamura S, Yoshioka M, Onodera J, Kogure K, Itoyama Y (1994) Expression of cytokines in brain lesions in subacute sclerosing panencephalitis. Neurology, 44: 710-715.
28. Nakajima K, Kohsaka S (2001) Microglia: activation and their significance in the central nervous system. J Biochem (Tokyo), 130: 169-175.
29. Ochs RL, Stein T Jr, Andarde LE, Gallo D, Chan EK, Tan EM, Brasch K (1995) Formation of nuclear bodies in hepatocytes of estrogen-treated roosters. Mol Biol Cell, 6: 345-356.
30. Oh WJ, Kim EK, Ko JH, Yoo SH, Hahn SH, Yoo OJ (2002) Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene. Eur J Biochem, 8: 2151-2161.
31. Pearson VL, Rothewell NJ, Toulmond S (1999) Excitotoxic brain damage in the rat induces interleukin-1beta protein in microglia and astrocytes: correlation with the progression of cell death. Glia, 25: 311-323.
32. Perimutter LS, Baron E, Chang Chui H (1990) Morphological association between microglia and senile plaque amyloid in Alzheimer's disease. Neurosci Lett, 119: 32-36.
33. Perimutter LS, Scott SA, Chang Chui H (1991) The role of microglia in the cortical neuropathology of Alzheimer disease. Bull Clin Neurosci, 56: 120-130.
34. Raivich G, Bochatschek M, Kloss CUA, Werner A, Jones LL, Kreutzberg GW (1999) Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res Rev, 30: 77-105.
35. Reichmann G, Schroeter M, Jander S, Fischer HG (2002) Dendritic cells and dendritic-like microglia in focal cortical ischemia of mouse brain. J Neuroimmunol, 129: 125-132
36. Roher A, Gray EG, Paula-Barbosa M (1988) Alzheimer's disease: coated vesicles, coated pits and the amyloid-related cell. Proc Soc Lond, 232: 367-373.
37. Schneider-Schaulies J, Schneider-Schaulies S, Ter Meulen V (1993) Differential induction of cytokines by primary and persistent measles virus infection of human glial cells. Virology, 195: 219-228.
38. Schul W, van Driel R, de Jong L (1998) Coiled bodies and U2 snRNA genes adjacent to coiled bodies are enriched in factors required for snRNA transcription. Mol Biol Cell, 9: 1025-1036.
39. Sheng JG, Mrak RE, Griffin WS (1998) Enlarged and phagocytic but not primed, interleukin-1 alpha-immunoreactive microglia increase with age in normal human brain. Acta Neuropathol, 95: 229-234.
40. Shibata Y, Nakamura T (2002) Defective flap endonuclease 1 activity in mammalian cells is associated with impaired DNA repair and prolonged S phase delay. J Biol Chem, 277: 746-754.
41. Sidoria-Reyes AG, Ferman-Cano F, Garcia GR, Rodriguez-Velasco A (2001) Wilson disease. Report of a case of autopsy with copper tissue quantification and electronic microscopy. Rev Gastroenterol Mex, 66: 38-41.
42. Stalder M, Deller T, Staufenbiel M, Jucker M (2001) 3D-reconstruction of microglia and amyloid in APP23 transgenic mice: no evidence of intracellular amyloid. Neurobiol-Aging, 3: 427-434.
43. Streit WJ (2000) Microglial response to brain injury: a brief synopsis. Toxicol Pathol, 28: 28-30.
44. Szpak GM, Lechowicz W, Lewandowska E, Bertrand E, Wierzba-Bobrowicz T, Gwiazda E, Schmidt-Sidor B, Dymecki J (2001) Neurones and microglia in central nervous system immune response to degenerative processes. I: Alzheimer's disease and Lewy body variant of Alzheimer's disease. Quantitative study. Folia Neuropathol, 3: 181-192.
45. Talley A, Perry S, Epstein LG, Gelbard HA (1994) TNF-A mediated cells apoptosis in SK-N-MC neuroblastoma cells: a model for neuronal cell loss in HIV-1 associated dementia. Ann Neurol, 36: 506-507.
46. Wierzba-Bobrowicz T, Gwiazda E, Kosno-Kruszewska E, Lewandowska E, Lechowicz W, Bertrand E, Szpak GM, Schmidt-Sidor B (2002) Morphological analysis of active microglia-rod and ramified in human brains affected by some neurological diseases (SSPE, Alzheimer's disease and Wilson's disease). Folia Neuropathol, 40: 125-131.
47. Wiśniewski HM, Wegiel J, Wang KC, Kujawa M, Lach B (1998) Ultrastructural studies of the cells forming amyloid fibers in classical plaques. Can J Neurosci, 16: 535-541.
48. Yang MS, Park EJ, Sohn S, Kwon HJ, Shin WH, Pyo HK, Jin B, Choi KS, Jou I, Joe EH (2002) Interleukin-13 and -4 induce death of activated microglia. Glia 38: 273-280.
49. Xie Z, Wei M, Morgan TE, Fabrizio P, Han D, Finch CE, Longo VD (2002) Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolisaccharide-activated microglia. J Neurosci, 22: 3484-3492