메뉴 건너뛰기




Volumn 25, Issue 4, 1999, Pages 311-323

Excitotoxic brain damage in the rat induces interleukin-1β protein in microglia and astrocytes: Correlation with the progression of cell death

Author keywords

Cytokine; Gliosis; Methanoglutamate; Neurodegeneration

Indexed keywords

2,4 METHANOGLUTAMATE; 2,4-METHANOGLUTAMATE; GLUTAMIC ACID DERIVATIVE; INTERLEUKIN 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTOXIN;

EID: 0033557187     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(19990215)25:4<311::AID-GLIA1>3.0.CO;2-E     Document Type: Article
Times cited : (142)

References (61)
  • 1
    • 0027295901 scopus 로고
    • Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans
    • Baker AJ, Moulton RJ, MacMillan VH, Shedden PM. 1993. Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans. J Neurosurg 79:369-372.
    • (1993) J Neurosurg , vol.79 , pp. 369-372
    • Baker, A.J.1    Moulton, R.J.2    MacMillan, V.H.3    Shedden, P.M.4
  • 3
    • 0026087219 scopus 로고
    • 3 (peripheral type benzodiazepine) binding sites in the rat cortex and striatum after local injection of interleukin-1, tumor necrosis factor-A and lipopolysaccharide
    • 3 (peripheral type benzodiazepine) binding sites in the rat cortex and striatum after local injection of interleukin-1, tumor necrosis factor-A and lipopolysaccharide. Brain Res 543:194-200.
    • (1991) Brain Res , vol.543 , pp. 194-200
    • Bourdiol, F.1    Toulmond, S.2    Serrano, A.3    Benavides, J.4    Scatton, B.5
  • 4
    • 0030000385 scopus 로고    scopus 로고
    • The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease
    • Breitner JCS. 1996. The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease. Annu Rev Med 47:401-411.
    • (1996) Annu Rev Med , vol.47 , pp. 401-411
    • Breitner, J.C.S.1
  • 5
    • 0028176793 scopus 로고
    • Induction of interleukin-1β mRNA after focal cerebral ischaemia in the rat
    • Buttini M, Sauter A, Boddeke HWGM. 1994. Induction of interleukin-1β mRNA after focal cerebral ischaemia in the rat. Mol Brain Res 23:126-134.
    • (1994) Mol Brain Res , vol.23 , pp. 126-134
    • Buttini, M.1    Sauter, A.2    Boddeke, H.W.G.M.3
  • 6
    • 0029620390 scopus 로고
    • Interleukin-1 and tumor necrosis factor-α synergistically mediate neurotoxicity: Involvement of nitric oxide and N-methyl-D-aspartate receptors
    • Chao CC, Hu S, Ehrlich L, Peterson PK. 1995. Interleukin-1 and tumor necrosis factor-α synergistically mediate neurotoxicity: involvement of nitric oxide and N-methyl-D-aspartate receptors. Brain Behav Immunol 9:355-365.
    • (1995) Brain Behav Immunol , vol.9 , pp. 355-365
    • Chao, C.C.1    Hu, S.2    Ehrlich, L.3    Peterson, P.K.4
  • 7
    • 0030108525 scopus 로고    scopus 로고
    • Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
    • Chao CC, Hu S, Sheng WS, Bu D, Bukrinsky MI, Peterson PK. 1996. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia 16:276-284.
    • (1996) Glia , vol.16 , pp. 276-284
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Bu, D.4    Bukrinsky, M.I.5    Peterson, P.K.6
  • 9
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA. 1996. Biologic basis for interleukin-1 in disease. Blood 87:2095-2147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 10
    • 0029055091 scopus 로고
    • Glia modulate the response of murine cortical neurons to excitotoxicity: Glia exacerbate AMPA neurotoxicity
    • Dugan LL, Bruno VMG, Amagasu SM, Giffard RG. 1995. Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity. J Neurosci 15:4545-4555.
    • (1995) J Neurosci , vol.15 , pp. 4545-4555
    • Dugan, L.L.1    Bruno, V.M.G.2    Amagasu, S.M.3    Giffard, R.G.4
  • 12
    • 0029807883 scopus 로고    scopus 로고
    • Evolving stroke and the ischemic penumbra
    • Fisher M, Garcia JH 1996. Evolving stroke and the ischemic penumbra. Neurology 47:884-888.
    • (1996) Neurology , vol.47 , pp. 884-888
    • Fisher, M.1    Garcia, J.H.2
  • 13
    • 0020461752 scopus 로고
    • Production of prostaglandin E and interleukin-1-like factor by cultured astrocytes and C6 glioma cells
    • Fontana A, Kristensen F, Dubs R, Gemsa D, Weber E. 1982. Production of prostaglandin E and interleukin-1-like factor by cultured astrocytes and C6 glioma cells. J Immunol 129:2413-2419.
    • (1982) J Immunol , vol.129 , pp. 2413-2419
    • Fontana, A.1    Kristensen, F.2    Dubs, R.3    Gemsa, D.4    Weber, E.5
  • 14
    • 0024997223 scopus 로고
    • Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes
    • Gadient RA, Cron KC, Otten U. 1990. Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes. Neurosci Lett 117:335-340.
    • (1990) Neurosci Lett , vol.117 , pp. 335-340
    • Gadient, R.A.1    Cron, K.C.2    Otten, U.3
  • 15
    • 0022441440 scopus 로고
    • Interleukin-1 of the central nervous system is produced by ameboid microglia
    • Giulian D, Baker TJ, Shih L-C N, Lachman LB. 1986. Interleukin-1 of the central nervous system is produced by ameboid microglia. J Exp Med 164:594-604.
    • (1986) J Exp Med , vol.164 , pp. 594-604
    • Giulian, D.1    Baker, T.J.2    Shih, L.-C.N.3    Lachman, L.B.4
  • 16
    • 0021912473 scopus 로고
    • Interleukin-1 stimulation of astroglial proliferation after brain injury
    • Giulian D, Lachman LB. 1985. Interleukin-1 stimulation of astroglial proliferation after brain injury. Science 228:497-498.
    • (1985) Science , vol.228 , pp. 497-498
    • Giulian, D.1    Lachman, L.B.2
  • 17
    • 0028105846 scopus 로고
    • Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture
    • Giulian D, Li J, Leara B, Keenen C. 1994a. Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture. Neurochem Int 25:227-233.
    • (1994) Neurochem Int , vol.25 , pp. 227-233
    • Giulian, D.1    Li, J.2    Leara, B.3    Keenen, C.4
  • 18
    • 0028596581 scopus 로고
    • The impact of microglia-derived cytokines upon gliosis in the CNS
    • Giulian D, Li J, Li X, George J, Rutecki PA. 1994b. The impact of microglia-derived cytokines upon gliosis in the CNS. Dev Neurosci 16:128-136.
    • (1994) Dev Neurosci , vol.16 , pp. 128-136
    • Giulian, D.1    Li, J.2    Li, X.3    George, J.4    Rutecki, P.A.5
  • 19
    • 0029071410 scopus 로고
    • Hypothermia attenuates the normal increase in interleukin 1β RNA and nerve growth factor following traumatic brain injury in the rat
    • Goss JR, Styren SD, Miller PD, Kochanek PM, Palmer AM, Marion DW and DeKosky ST. 1995. Hypothermia attenuates the normal increase in interleukin 1β RNA and nerve growth factor following traumatic brain injury in the rat. J Neurotrauma 12:159-167.
    • (1995) J Neurotrauma , vol.12 , pp. 159-167
    • Goss, J.R.1    Styren, S.D.2    Miller, P.D.3    Kochanek, P.M.4    Palmer, A.M.5    Marion, D.W.6    Dekosky, S.T.7
  • 20
    • 0028167986 scopus 로고
    • Microglial interleukin-1 alpha expression in human head injury: Correlations with neuronal and neuritic beta-amyloid precursor protein expression
    • Griffin WS, Sheng JG, Gentleman SM, Graham DI, Mrak RE, Roberts GW. 1994. microglial interleukin-1 alpha expression in human head injury: correlations with neuronal and neuritic beta-amyloid precursor protein expression. Neurosci Lett 176:133-136.
    • (1994) Neurosci Lett , vol.176 , pp. 133-136
    • Griffin, W.S.1    Sheng, J.G.2    Gentleman, S.M.3    Graham, D.I.4    Mrak, R.E.5    Roberts, G.W.6
  • 21
    • 0030298412 scopus 로고    scopus 로고
    • Adenovirus-mediated over-expression of interleukin-1 receptor antagonist reduces susceptibility to excitotoxic brain injury in perinatal rats
    • Hagan P, Barks JDE, Yabut M, Davidson BL, Roessler B, Silverstein FS. 1996a. Adenovirus-mediated over-expression of interleukin-1 receptor antagonist reduces susceptibility to excitotoxic brain injury in perinatal rats. Neuroscience 75:1033-1045.
    • (1996) Neuroscience , vol.75 , pp. 1033-1045
    • Hagan, P.1    Barks, J.D.E.2    Yabut, M.3    Davidson, B.L.4    Roessler, B.5    Silverstein, F.S.6
  • 22
    • 0029840954 scopus 로고    scopus 로고
    • Intracerebral NMDA injection stimulates production of interleukin-1β in perinatal rat brain
    • Hagan P, Poole S, Bristow AF, Tilders F, Silverstein FS. 1996b. Intracerebral NMDA injection stimulates production of interleukin-1β in perinatal rat brain. J Neurochem 67:2215-2218.
    • (1996) J Neurochem , vol.67 , pp. 2215-2218
    • Hagan, P.1    Poole, S.2    Bristow, A.F.3    Tilders, F.4    Silverstein, F.S.5
  • 24
    • 0027932457 scopus 로고
    • Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS
    • Hewett SJ, Csernansky CA, Choi DW. 1994. Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS. Neuron 13:487-494.
    • (1994) Neuron , vol.13 , pp. 487-494
    • Hewett, S.J.1    Csernansky, C.A.2    Choi, D.W.3
  • 26
    • 0029140838 scopus 로고
    • Cytokine modulation of murine microglial cell superoxide production
    • Hu S, Sheng WS, Peterson PK, Chao CC. 1995. Cytokine modulation of murine microglial cell superoxide production. Glia 13:45-50.
    • (1995) Glia , vol.13 , pp. 45-50
    • Hu, S.1    Sheng, W.S.2    Peterson, P.K.3    Chao, C.C.4
  • 27
    • 0025242563 scopus 로고
    • Massive increase in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury
    • Katayama Y, Becker D, Tamura T, Hovda, DA. 1990. Massive increase in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J Neurosurg 73:889-900.
    • (1990) J Neurosurg , vol.73 , pp. 889-900
    • Katayama, Y.1    Becker, D.2    Tamura, T.3    Hovda, D.A.4
  • 28
    • 0030608825 scopus 로고    scopus 로고
    • Prostaglandin E1 prevents apoptotic cell death in superficial dorsal horn of rat spinal cord
    • Kawamura T, Akira T, Watanabe M, Katigani Y. 1997. Prostaglandin E1 prevents apoptotic cell death in superficial dorsal horn of rat spinal cord. Neuropharmacology 36:1023-1030.
    • (1997) Neuropharmacology , vol.36 , pp. 1023-1030
    • Kawamura, T.1    Akira, T.2    Watanabe, M.3    Katigani, Y.4
  • 29
    • 0029126944 scopus 로고
    • Protein synthesis-dependent induction of interleukin-1 beta by lipppolysaccharide is inhibited by dexamethasone via mRNA destabilization in human astroglial cells
    • Kimberlin DW, Willis SA, McCracken GH, Nisen PD. 1995. Protein synthesis-dependent induction of interleukin-1 beta by lipppolysaccharide is inhibited by dexamethasone via mRNA destabilization in human astroglial cells. J Clin Immunol 15:199-204.
    • (1995) J Clin Immunol , vol.15 , pp. 199-204
    • Kimberlin, D.W.1    Willis, S.A.2    McCracken, G.H.3    Nisen, P.D.4
  • 30
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 32
    • 0031595870 scopus 로고    scopus 로고
    • Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat
    • Lawrence CB, Allan SM, Rothwell NJ. 1998. Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. Eur J Neurosci 10:1188-1195.
    • (1998) Eur J Neurosci , vol.10 , pp. 1188-1195
    • Lawrence, C.B.1    Allan, S.M.2    Rothwell, N.J.3
  • 33
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurological disorders
    • Lipton SA, Rosenberg PA. 1994. Excitatory amino acids as a final common pathway for neurological disorders. N Engl J Med 330: 613-622.
    • (1994) N Engl J Med , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 34
    • 0029744418 scopus 로고    scopus 로고
    • Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat
    • Loddick SA, Rothwell NJ. 1996. Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab 16:932-940.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 932-940
    • Loddick, S.A.1    Rothwell, N.J.2
  • 35
    • 0029773397 scopus 로고    scopus 로고
    • An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat
    • Loddick SA, MacKenzie A, Rothwell NJ. 1996. An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat. NeuroReport 7:1465-1468.
    • (1996) Neuroreport , vol.7 , pp. 1465-1468
    • Loddick, S.A.1    MacKenzie, A.2    Rothwell, N.J.3
  • 36
    • 0027050672 scopus 로고
    • Substance P stimulates IL-1 production by astrocytes via intracellular calcium
    • Martin FC, Charles AC, Sanderson MJ, Merrill JE. 1992. Substance P stimulates IL-1 production by astrocytes via intracellular calcium. Brain Res 599:13-18.
    • (1992) Brain Res , vol.599 , pp. 13-18
    • Martin, F.C.1    Charles, A.C.2    Sanderson, M.J.3    Merrill, J.E.4
  • 37
  • 38
    • 0025063609 scopus 로고
    • Excitatory amino acids neurotoxicity and neurodegenerative disease
    • Meldrum B, Garthwaite J. 1990. Excitatory amino acids neurotoxicity and neurodegenerative disease. Trends Pharmacol Sci 11:397-387.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 397-1387
    • Meldrum, B.1    Garthwaite, J.2
  • 39
    • 0025844833 scopus 로고
    • Effects of kainic acid on messenger RNA levels of IL-1β, IL-6, TNF-α and LIF in the rat brain
    • Minami M, Kuraishi Y, Satoh M. 1991. Effects of kainic acid on messenger RNA levels of IL-1β, IL-6, TNF-α and LIF in the rat brain. Biochem Biophys Res Commun 176:593-598.
    • (1991) Biochem Biophys Res Commun , vol.176 , pp. 593-598
    • Minami, M.1    Kuraishi, Y.2    Satoh, M.3
  • 40
    • 0026530776 scopus 로고
    • Induction of interleukin-1β mRNA in rat brain after transient forebrain ischemia
    • Minami M, Kuraishi Y, Yabuuchi K, Yamazaki A, Satoh M. 1992. Induction of interleukin-1β mRNA in rat brain after transient forebrain ischemia. J Neurochem 58:390-392.
    • (1992) J Neurochem , vol.58 , pp. 390-392
    • Minami, M.1    Kuraishi, Y.2    Yabuuchi, K.3    Yamazaki, A.4    Satoh, M.5
  • 43
    • 0030898608 scopus 로고    scopus 로고
    • Inflammatory mechanisms in Alzheimer disease: The role of beta-amyloid/glial interactions
    • Patcher JS. 1997. Inflammatory mechanisms in Alzheimer Disease: the role of beta-amyloid/glial interactions. Mol Psychiatry 2:91-95.
    • (1997) Mol Psychiatry , vol.2 , pp. 91-95
    • Patcher, J.S.1
  • 45
    • 0025720505 scopus 로고
    • Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate
    • Piani D, Frei K, Do KQ, Cuénod M, Fontana A. 1991. Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate. Neurosci Lett 133:159-162.
    • (1991) Neurosci Lett , vol.133 , pp. 159-162
    • Piani, D.1    Frei, K.2    Do, K.Q.3    Cuénod, M.4    Fontana, A.5
  • 46
    • 0027369531 scopus 로고
    • Glutamate uptake by astrocytes is inhibited by reactive oxygen intermediates but not by other macrophage-derived molecules including cytokines, leukotrienesor platelet-activating factor
    • Piani D, Frei K, Pfister H-W, Fontana A. 1993. Glutamate uptake by astrocytes is inhibited by reactive oxygen intermediates but not by other macrophage-derived molecules including cytokines, leukotrienesor platelet-activating factor. J Neuroimmunol 48:99-104.
    • (1993) J Neuroimmunol , vol.48 , pp. 99-104
    • Piani, D.1    Frei, K.2    Pfister, H.-W.3    Fontana, A.4
  • 48
    • 0026656192 scopus 로고
    • Interleukin-1 receptor antagonists inhibits ischaemic and excitotoxic neuronal damage in the rat
    • Relton J K, Rothwell N J. 1992. Interleukin-1 receptor antagonists inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain Res Bull 23:243-246.
    • (1992) Brain Res Bull , vol.23 , pp. 243-246
    • Relton, J.K.1    Rothwell, N.J.2
  • 49
    • 0031438499 scopus 로고    scopus 로고
    • The role of interleukin-1 in acute neurodegeneration and stroke: Pathophysiological and therapeutic implications
    • Rothwell N J, Allan S, Toulmond S. 1997. The role of interleukin-1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications. J Clin Invest 100:2648-2651.
    • (1997) J Clin Invest , vol.100 , pp. 2648-2651
    • Rothwell, N.J.1    Allan, S.2    Toulmond, S.3
  • 50
    • 0030729296 scopus 로고    scopus 로고
    • Global forebrain ischemia results in differential cellular expression of interleukin-1β (IL-1β) and its receptors at mRNA and protein level
    • Sairanen TR, Lindsberg PJ, Brenner M, Siren A-L. 1997. Global forebrain ischemia results in differential cellular expression of interleukin-1β (IL-1β) and its receptors at mRNA and protein level. J Cereb Blood Flow Metab 17:1107-1120.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 1107-1120
    • Sairanen, T.R.1    Lindsberg, P.J.2    Brenner, M.3    Siren, A.-L.4
  • 51
    • 0031157247 scopus 로고    scopus 로고
    • Regulation by interleukin-1β of formation of a line of delimiting astrocytes following prenatal trauma to the brain mouse
    • Scripter JL, Ko J, Kow K, Arimura A, Ide CF. 1997. Regulation by interleukin-1β of formation of a line of delimiting astrocytes following prenatal trauma to the brain mouse. Exp Neurol 145:329-341.
    • (1997) Exp Neurol , vol.145 , pp. 329-341
    • Scripter, J.L.1    Ko, J.2    Kow, K.3    Arimura, A.4    Ide, C.F.5
  • 52
    • 0029047891 scopus 로고
    • Interleukin-1β attenuates excitatory amino acid-induced neurodegeneration in vitro: Involvement of nerve growth factor
    • Strijbos PJL, Rothwell NJ. 1995. Interleukin-1β attenuates excitatory amino acid-induced neurodegeneration in vitro: involvement of nerve growth factor. J Neurosci 15:3468-3474.
    • (1995) J Neurosci , vol.15 , pp. 3468-3474
    • Strijbos, P.J.L.1    Rothwell, N.J.2
  • 53
    • 0027400847 scopus 로고
    • Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion
    • Taupin V, Toulmond S, Serrano A, Benavides J, Zavala F. 1993. Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. J Neuroimmunol 42:177-186.
    • (1993) J Neuroimmunol , vol.42 , pp. 177-186
    • Taupin, V.1    Toulmond, S.2    Serrano, A.3    Benavides, J.4    Zavala, F.5
  • 54
    • 0027255070 scopus 로고
    • Biochemical and histological alterations induced by fluid percussion brain injury in the rat
    • Toulmond S, Duval D, Serrano A, Scatton B, Benavides J. 1993a. Biochemical and histological alterations induced by fluid percussion brain injury in the rat. Brain Res 620:24-31.
    • (1993) Brain Res , vol.620 , pp. 24-31
    • Toulmond, S.1    Duval, D.2    Serrano, A.3    Scatton, B.4    Benavides, J.5
  • 56
    • 0028982742 scopus 로고
    • Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat
    • Toulmond S, Rothwell NJ. 1995. Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat. Brain Res 671:261-266.
    • (1995) Brain Res , vol.671 , pp. 261-266
    • Toulmond, S.1    Rothwell, N.J.2
  • 57
    • 0025820808 scopus 로고
    • Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: Evidence of a role for microglia in cytokine production
    • Woodroofe MN, Sarna GS, Wadhwa M, Hayes GM, Loughlin A J, Tinker A, Cuzner ML. 1991. Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production. J Neuroimmunol 33:227-236.
    • (1991) J Neuroimmunol , vol.33 , pp. 227-236
    • Woodroofe, M.N.1    Sarna, G.S.2    Wadhwa, M.3    Hayes, G.M.4    Loughlin, A.J.5    Tinker, A.6    Cuzner, M.L.7
  • 59
    • 0027296611 scopus 로고
    • In situ hybridization study of interleukin-1β mRNA induced by kainic acid in the rat brain
    • Yabuuchi K, Minami M, Katsumata S, Satoh M. 1993. In situ hybridization study of interleukin-1β mRNA induced by kainic acid in the rat brain. Mol Brain Res 20:153-161.
    • (1993) Mol Brain Res , vol.20 , pp. 153-161
    • Yabuuchi, K.1    Minami, M.2    Katsumata, S.3    Satoh, M.4
  • 60
    • 0030899994 scopus 로고    scopus 로고
    • Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury
    • Yang G-Y, Zhao Y-J, Davidson BL, Betz AL. 1997. Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury. Brain Res 751:181-188.
    • (1997) Brain Res , vol.751 , pp. 181-188
    • Yang, G.-Y.1    Zhao, Y.-J.2    Davidson, B.L.3    Betz, A.L.4
  • 61
    • 0030732222 scopus 로고    scopus 로고
    • Induction of interleukin-1β converting enzyme (ICE) in murine microglia by lipopolysaccharide
    • Yao J, Johnson RW. 1997. Induction of interleukin-1β converting enzyme (ICE) in murine microglia by lipopolysaccharide. Mol Brain Res 51:170-178.
    • (1997) Mol Brain Res , vol.51 , pp. 170-178
    • Yao, J.1    Johnson, R.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.