(2S,4R)-4-methylglutamic acid (SYM 2081): A selective, high-affinity ligand for kainate receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 280, Issue 1, 1997, Pages 422-427

  Zhou, L M ^a,b,d   Gu, Z Q ^a   Costa, A M ^a   Yamada, K A ^c   Mansson, P E ^a   Giordano, T ^a   Skolnick, P ^b   Jones, K A ^a,e  

^a Symphony Pharmaceuticals   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NW University Medical Center ^*  (United States)

^e H LUNDBECK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLGLUTAMIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CONCANAVALIN A; GLUTAMIC ACID DERIVATIVE; ION CHANNEL; KAINIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DESENSITIZATION; DRUG POTENCY; DRUG RECEPTOR BINDING; LIGAND BINDING; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SPINAL GANGLION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMATES; HUMANS; KAINIC ACID; LIGANDS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030999770     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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