-
1
-
-
0033772073
-
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
-
Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwartz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI 2000 Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 26:163-175
-
(2000)
Nat Genet
, vol.26
, pp. 163-175
-
-
Horikawa, Y.1
Oda, N.2
Cox, N.J.3
Li, X.4
Orho-Melander, M.5
Hara, M.6
Hinokio, Y.7
Lindner, T.H.8
Mashima, H.9
Schwartz, P.E.10
Del Bosque-Plata, L.11
Horikawa, Y.12
Oda, Y.13
Yoshiuchi, I.14
Colilla, S.15
Polonsky, K.S.16
Wei, S.17
Concannon, P.18
Iwasaki, N.19
Schulze, J.20
Baier, L.J.21
Bogardus, C.22
Groop, L.23
Boerwinkle, E.24
Hanis, C.L.25
Bell, G.I.26
more..
-
2
-
-
0033797241
-
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance
-
Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen G-Q, Mott D, Knowler WC, Cox NJ, Horikawa Y, Oda N, Bell GI, Bogardus C 2001 A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest 106:R69-R73
-
(2001)
J Clin Invest
, vol.106
-
-
Baier, L.J.1
Permana, P.A.2
Yang, X.3
Pratley, R.E.4
Hanson, R.L.5
Shen, G.-Q.6
Mott, D.7
Knowler, W.C.8
Cox, N.J.9
Horikawa, Y.10
Oda, N.11
Bell, G.I.12
Bogardus, C.13
-
3
-
-
0035458548
-
Calpains play a role in insulin secretion and action
-
Screenan SK, Zhou Y-P, Otani K, Hansen PA, Currie KPM, Pan C-Y, Lee J-P, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS 2001 Calpains play a role in insulin secretion and action. Diabetes 50:2013-2020
-
(2001)
Diabetes
, vol.50
, pp. 2013-2020
-
-
Screenan, S.K.1
Zhou, Y.-P.2
Otani, K.3
Hansen, P.A.4
Currie, K.P.M.5
Pan, C.-Y.6
Lee, J.-P.7
Ostrega, D.M.8
Pugh, W.9
Horikawa, Y.10
Cox, N.J.11
Hanis, C.L.12
Burant, C.F.13
Fox, A.P.14
Bell, G.I.15
Polonsky, K.S.16
-
4
-
-
0030892186
-
Calpain: A cytosolic proteinase active at the membranes
-
Molinari M, Carafoli E 1997 Calpain: a cytosolic proteinase active at the membranes. J Membr Biol 156:1-8
-
(1997)
J Membr Biol
, vol.156
, pp. 1-8
-
-
Molinari, M.1
Carafoli, E.2
-
5
-
-
0346725912
-
Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes
-
Paul DS, Harmon AW, Winston CP, Patel YM 2003 Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes. Biochem J 15:625-632
-
(2003)
Biochem J
, vol.15
, pp. 625-632
-
-
Paul, D.S.1
Harmon, A.W.2
Winston, C.P.3
Patel, Y.M.4
-
6
-
-
0038748363
-
A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin
-
Zhou Y-P, Sreenan S, Pan C-Y, Currie KPM, Bindokas VP, Horikawa Y, Lee J-P, Osrega D, Ahmed N, Baldwin AC, Cox NJ, Fox AP, Miller RJ, Bell GI, Polonsky KS 2003 A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin. Metabolism 5:528-534
-
(2003)
Metabolism
, vol.5
, pp. 528-534
-
-
Zhou, Y.-P.1
Sreenan, S.2
Pan, C.-Y.3
Currie, K.P.M.4
Bindokas, V.P.5
Horikawa, Y.6
Lee, J.-P.7
Osrega, D.8
Ahmed, N.9
Baldwin, A.C.10
Cox, N.J.11
Fox, A.P.12
Miller, R.J.13
Bell, G.I.14
Polonsky, K.S.15
-
7
-
-
0003014882
-
Metabolic consequences of a family history of NIDDM (the Botnia study): Evidence for sex-specific parental effects
-
Groop L, Forsblom C, Lehtovirta M, Tuomi T, Karanko S, Nissen M, Ehrnström BO, Forsen B, Isomaa B, Snickars B, Taskinen MR 1996 Metabolic consequences of a family history of NIDDM (the Botnia study): evidence for sex-specific parental effects. Diabetes 45:1585-1593
-
(1996)
Diabetes
, vol.45
, pp. 1585-1593
-
-
Groop, L.1
Forsblom, C.2
Lehtovirta, M.3
Tuomi, T.4
Karanko, S.5
Nissen, M.6
Ehrnström, B.O.7
Forsen, B.8
Isomaa, B.9
Snickars, B.10
Taskinen, M.R.11
-
8
-
-
0028091753
-
Metabolic and genetic characterization of prediabetic states: Sequence of events leading to non-insulin-dependent diabetes mellitus
-
Beck-Nielsen H, Groop L 1994 Metabolic and genetic characterization of prediabetic states: sequence of events leading to non-insulin-dependent diabetes mellitus. J Clin Invest 94:1714-1721
-
(1994)
J Clin Invest
, vol.94
, pp. 1714-1721
-
-
Beck-Nielsen, H.1
Groop, L.2
-
10
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G 1997 Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46:3-10
-
(1997)
Diabetes
, vol.46
, pp. 3-10
-
-
Boden, G.1
-
11
-
-
0032960890
-
Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects
-
Jacob S, Machann J, Rett K, Brechtel K, Volk A, Renn W, Maerker E, Matthaei S, Schick F, Claussen CD, Haring HU 1999 Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. Diabetes 48:1113-1119
-
(1999)
Diabetes
, vol.48
, pp. 1113-1119
-
-
Jacob, S.1
Machann, J.2
Rett, K.3
Brechtel, K.4
Volk, A.5
Renn, W.6
Maerker, E.7
Matthaei, S.8
Schick, F.9
Claussen, C.D.10
Haring, H.U.11
-
12
-
-
0032764784
-
Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans
-
Perseghin G, Scifo P, De Cobelli F, Pagliato E, Battezzati A, Arcelloni C, Vanzulli A, Testolin G, Pozza G, Del Maschio A, Luzi L 1999 Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans. Diabetes 48:1600-1606
-
(1999)
Diabetes
, vol.48
, pp. 1600-1606
-
-
Perseghin, G.1
Scifo, P.2
De Cobelli, F.3
Pagliato, E.4
Battezzati, A.5
Arcelloni, C.6
Vanzulli, A.7
Testolin, G.8
Pozza, G.9
Del Maschio, A.10
Luzi, L.11
-
13
-
-
0036321080
-
Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels
-
Orho-Melander M, Klannemark M, Svensson M, Ridderstråle M, Lindgren C, Groop L 2002 Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels. Diabetes 51:2658-2664
-
(2002)
Diabetes
, vol.51
, pp. 2658-2664
-
-
Orho-Melander, M.1
Klannemark, M.2
Svensson, M.3
Ridderstråle, M.4
Lindgren, C.5
Groop, L.6
-
15
-
-
0036124605
-
Calpain 10 gene polymorphisms are related, not to type 2 diabetes, but to increased serum cholesterol in Japanese
-
Daimon M, Oizumi T, Saitoh T, Kameda W, Yamaguchi H, Ohnuma H, Igarashi M, Manaka H, Kato T 2002 Calpain 10 gene polymorphisms are related, not to type 2 diabetes, but to increased serum cholesterol in Japanese. Diabetes Res Clin Pract 56:147-152
-
(2002)
Diabetes Res Clin Pract
, vol.56
, pp. 147-152
-
-
Daimon, M.1
Oizumi, T.2
Saitoh, T.3
Kameda, W.4
Yamaguchi, H.5
Ohnuma, H.6
Igarashi, M.7
Manaka, H.8
Kato, T.9
-
16
-
-
0021180032
-
Blot hybridisation analysis of genomic DNA
-
Vandenplas S, Wiid I, Grobler-Rabie A, Brebner K, Ricketts M, Wallis G, Bester A, Boyd C, Mathew C 1984 Blot hybridisation analysis of genomic DNA. J Med Genet 21:164-172
-
(1984)
J Med Genet
, vol.21
, pp. 164-172
-
-
Vandenplas, S.1
Wiid, I.2
Grobler-Rabie, A.3
Brebner, K.4
Ricketts, M.5
Wallis, G.6
Bester, A.7
Boyd, C.8
Mathew, C.9
-
17
-
-
0035718894
-
Reduced skeletal muscle calpain-10 transcript level is due to cumulative decrease in major isoforms
-
Yang X, Pratley RE, Baier LJ, Horikawa Y, Bell GI, Bogardus C, Permana PA 2001 Reduced skeletal muscle calpain-10 transcript level is due to cumulative decrease in major isoforms. Mol Genet Metab 73:111-113
-
(2001)
Mol Genet Metab
, vol.73
, pp. 111-113
-
-
Yang, X.1
Pratley, R.E.2
Baier, L.J.3
Horikawa, Y.4
Bell, G.I.5
Bogardus, C.6
Permana, P.A.7
-
18
-
-
0029886532
-
Parametric and non-parametric linkage analysis: A unified multipoint approach
-
Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES 1996 Parametric and non-parametric linkage analysis: a unified multipoint approach. Am J Hum Genet 58:1347-1363
-
(1996)
Am J Hum Genet
, vol.58
, pp. 1347-1363
-
-
Kruglyak, L.1
Daly, M.J.2
Reeve-Daly, M.P.3
Lander, E.S.4
-
19
-
-
0035461345
-
Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans
-
Stumvoll M, Fritsche A, Madaus A, Stefan N, Weisser M, Machicao F, Haring H 2001 Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans. Diabetes 50:2161-2163
-
(2001)
Diabetes
, vol.50
, pp. 2161-2163
-
-
Stumvoll, M.1
Fritsche, A.2
Madaus, A.3
Stefan, N.4
Weisser, M.5
Machicao, F.6
Haring, H.7
-
20
-
-
0035205377
-
Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: No evidence of association
-
Tsai HJ, Sun G, Weeks DE, Kaushal R, Wolujewicz M, McGarvey ST, Tufa J, Viali S, Deka R 2001 Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: no evidence of association. Am J Hum Genet 69:1236-1244
-
(2001)
Am J Hum Genet
, vol.69
, pp. 1236-1244
-
-
Tsai, H.J.1
Sun, G.2
Weeks, D.E.3
Kaushal, R.4
Wolujewicz, M.5
McGarvey, S.T.6
Tufa, J.7
Viali, S.8
Deka, R.9
-
21
-
-
0036092048
-
SNP43 of CAPN10 and the risk of type 2 diabetes in African-Americans
-
Garant MJ, Kao WHL, Brancati F, Coresh J, Rami TM, Hanis CL, Boerwinkle E, Shuldiner AR 2002 SNP43 of CAPN10 and the risk of type 2 diabetes in African-Americans. Diabetes 51:231-237
-
(2002)
Diabetes
, vol.51
, pp. 231-237
-
-
Garant, M.J.1
Kao, W.H.L.2
Brancati, F.3
Coresh, J.4
Rami, T.M.5
Hanis, C.L.6
Boerwinkle, E.7
Shuldiner, A.R.8
-
22
-
-
0036191328
-
Polymorphism in the calpain 10 gene influences glucose metabolism in human fat cells
-
Hoffstedt J, Ryden M, Löfgren P, Orho-Melander M, Groop L, Arner P 2002 Polymorphism in the calpain 10 gene influences glucose metabolism in human fat cells. Diabetologia 45:276-282
-
(2002)
Diabetologia
, vol.45
, pp. 276-282
-
-
Hoffstedt, J.1
Ryden, M.2
Löfgren, P.3
Orho-Melander, M.4
Groop, L.5
Arner, P.6
-
23
-
-
0036316935
-
Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort
-
Fingerlin TE, Erdos MR, Watanabe RM, Wiles KR, Stringham HM, Mohlke KL, Silander K, Valle TT, Buchanan TA, Tuomilehto J, Bergman RN, Boehnke M, Collins FS 2002 Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort. Diabetes 51:1644-1648
-
(2002)
Diabetes
, vol.51
, pp. 1644-1648
-
-
Fingerlin, T.E.1
Erdos, M.R.2
Watanabe, R.M.3
Wiles, K.R.4
Stringham, H.M.5
Mohlke, K.L.6
Silander, K.7
Valle, T.T.8
Buchanan, T.A.9
Tuomilehto, J.10
Bergman, R.N.11
Boehnke, M.12
Collins, F.S.13
-
24
-
-
0036099118
-
Homozygous combination of calpain 10 gene haplotype is associated with type 2 diabetes mellitus in a Polish population
-
Malecki MT, Moczulski DK, Klupa T, Wanic K, Cyganek K, Frey J, Sieradzki J 2002 Homozygous combination of calpain 10 gene haplotype is associated with type 2 diabetes mellitus in a Polish population. Eur J Endocrinol 146:695-699
-
(2002)
Eur J Endocrinol
, vol.146
, pp. 695-699
-
-
Malecki, M.T.1
Moczulski, D.K.2
Klupa, T.3
Wanic, K.4
Cyganek, K.5
Frey, J.6
Sieradzki, J.7
-
25
-
-
0036594015
-
Association of the calpain-10 gene with microvascular function
-
Shore AC, Evans JC, Frayling TM, Clark PM, Lee BC, Horikawa Y, Hattersley AT, Tooke JE 2002 Association of the calpain-10 gene with microvascular function. Diabetologia 45:899-904
-
(2002)
Diabetologia
, vol.45
, pp. 899-904
-
-
Shore, A.C.1
Evans, J.C.2
Frayling, T.M.3
Clark, P.M.4
Lee, B.C.5
Horikawa, Y.6
Hattersley, A.T.7
Tooke, J.E.8
-
26
-
-
0036097653
-
Variation in the calpain-10 gene affects blood glucose levels in the British population
-
Lynn S, Evans JC, White C, Frayling TM, Hattersley AT, Turnbull DM, Horikawa Y, Cox NJ, Bell GI, Walker M 2002 Variation in the calpain-10 gene affects blood glucose levels in the British population. Diabetes 51:247-250
-
(2002)
Diabetes
, vol.51
, pp. 247-250
-
-
Lynn, S.1
Evans, J.C.2
White, C.3
Frayling, T.M.4
Hattersley, A.T.5
Turnbull, D.M.6
Horikawa, Y.7
Cox, N.J.8
Bell, G.I.9
Walker, M.10
-
27
-
-
0036895104
-
Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians
-
Rasmussen SK, Urhammer SA, Berglund L, Jensen JN, Hansen L, Echwald SM, Borch-Johnsen K, Horikawa Y, Mashima H, Lethell H, Cox NJ, Hansen T, Mell GI, Pedersen O 2002 Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. Diabetes 51:3561-3567
-
(2002)
Diabetes
, vol.51
, pp. 3561-3567
-
-
Rasmussen, S.K.1
Urhammer, S.A.2
Berglund, L.3
Jensen, J.N.4
Hansen, L.5
Echwald, S.M.6
Borch-Johnsen, K.7
Horikawa, Y.8
Mashima, H.9
Lethell, H.10
Cox, N.J.11
Hansen, T.12
Mell, G.I.13
Pedersen, O.14
-
28
-
-
0036020226
-
No evidence for involvement of the calpain-10 gene "high-risk" haplotype combination for non-insulin-dependent diabetes mellitus in early onset diabetes
-
Hinnley A, Antwerpen B, Geller F, Schäfer H, Siegfried W, Goldschmidt H, Remschmidt H, Ziegel A, Hebebrand J 2002 No evidence for involvement of the calpain-10 gene "high-risk" haplotype combination for non-insulin-dependent diabetes mellitus in early onset diabetes. Mol Genet Metab 76:152-156
-
(2002)
Mol Genet Metab
, vol.76
, pp. 152-156
-
-
Hinnley, A.1
Antwerpen, B.2
Geller, F.3
Schäfer, H.4
Siegfried, W.5
Goldschmidt, H.6
Remschmidt, H.7
Ziegel, A.8
Hebebrand, J.9
-
29
-
-
0034894047
-
Studies of association between the gene for calpain-10 and type 2 diabetes in the United Kingdom
-
Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Subba Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley A 2001 Studies of association between the gene for calpain-10 and type 2 diabetes in the United Kingdom. Am J Hum Genet 69:544-552
-
(2001)
Am J Hum Genet
, vol.69
, pp. 544-552
-
-
Evans, J.C.1
Frayling, T.M.2
Cassell, P.G.3
Saker, P.J.4
Hitman, G.A.5
Walker, M.6
Levy, J.C.7
O'Rahilly, S.8
Subba Rao, P.V.9
Bennett, A.J.10
Jones, E.C.11
Menzel, S.12
Prestwich, P.13
Simecek, N.14
Wishart, M.15
Dhillon, R.16
Fletcher, C.17
Millward, A.18
Demaine, A.19
Wilkin, T.20
Horikawa, Y.21
Cox, N.J.22
Bell, G.I.23
Ellard, S.24
McCarthy, M.I.25
Hattersley, A.26
more..
-
30
-
-
0036312406
-
Haplotype combinations of calpain 10 gene polymorphisms associate with increase risk of impaired glucose tolerance and type 2 diabetes in South Indians
-
Cassell P, Jackson AE, North BV, Evans JC, Syndercombe-Court D, Phillips C, Ramachandran A, Snehalatha C, Gelding SV, Vijayaravaghan S, Curtis D, Hitman GA 2002 Haplotype combinations of calpain 10 gene polymorphisms associate with increase risk of impaired glucose tolerance and type 2 diabetes in South Indians. Diabetes 51:1622-1628
-
(2002)
Diabetes
, vol.51
, pp. 1622-1628
-
-
Cassell, P.1
Jackson, A.E.2
North, B.V.3
Evans, J.C.4
Syndercombe-Court, D.5
Phillips, C.6
Ramachandran, A.7
Snehalatha, C.8
Gelding, S.V.9
Vijayaravaghan, S.10
Curtis, D.11
Hitman, G.A.12
-
31
-
-
0035985086
-
Insulin sensitivity of glucose disposal and lipolysis: No influence of common genetic variants in IRS-1 and CAPN10
-
Stumvoll M, Wahl HG, Machicao WF, Häring H 2002 Insulin sensitivity of glucose disposal and lipolysis: no influence of common genetic variants in IRS-1 and CAPN10. Diabetologia 45:651-656
-
(2002)
Diabetologia
, vol.45
, pp. 651-656
-
-
Stumvoll, M.1
Wahl, H.G.2
Machicao, W.F.3
Häring, H.4
-
33
-
-
0037119584
-
Allelic variation in human gene expression
-
Yan H, Yuan W, Velculescu VE, Vogelstein B, Kinzler KW 2002 Allelic variation in human gene expression. Science 297:1143
-
(2002)
Science
, vol.297
, pp. 1143
-
-
Yan, H.1
Yuan, W.2
Velculescu, V.E.3
Vogelstein, B.4
Kinzler, K.W.5
-
34
-
-
0030657602
-
Regional adipocity in man
-
Arner P 1997 Regional adipocity in man. J Endocrinol 155:191-192
-
(1997)
J Endocrinol
, vol.155
, pp. 191-192
-
-
Arner, P.1
|