Variation in the calpain-10 gene affects blood glucose levels in the British population

Diabetes

Volumn 51, Issue 1, 2002, Pages 247-250

  Lynn, Stephen ^a   Evans, Julie C ^b   White, Christopher ^a   Frayling, Timothy M ^c   Hattersley, Andrew T ^c   Turnbull, Doug M ^c   Horikawa, Yukio ^a   Cox, Nancy J ^c   Bell, Graeme I ^a   Walker, Mark ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF EXETER   (United Kingdom)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CALPAIN 10; UNCLASSIFIED DRUG;

ADULT; ARTICLE; FEMALE; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; GLUCOSE BLOOD LEVEL; HAPLOTYPE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RELEASE; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; POPULATION RESEARCH; PRIORITY JOURNAL; UNITED KINGDOM;

EID: 0036097653     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.51.1.247     Document Type: Article

References (8)

1. Pathogenesis of type 2 diabetes: Metabolic and molecular implications for identifying diabetes gene
2. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
3. Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom
4. A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance
5. Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans
6. Physiologic evaluation of factors controlling glucose tolerance
7. Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
8. Understanding oral glucose tolerance: Comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion