Circulating adiponectin levels increase in rats on caloric restriction: The potential for insulin sensitization

Experimental Gerontology

Volumn 39, Issue 7, 2004, Pages 1049-1059

  Zhu, Min ^a   Miura, Junnosuke ^b   Lu, Lucy X ^a   Bernier, Michel ^a   DeCabo, Rafael ^a   Lane, Mark A ^a   Roth, George S ^a   Ingram, Donald K ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b Gene Therapy and Therapeutics Branch   (United States)

Author keywords

Adiponectin; Caloric restriction; Insulin signaling; Lipid metabolism; PTP 1B

Indexed keywords

ADIPONECTIN; FATTY ACID; GLUCOSE; INSULIN; INSULIN RECEPTOR; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN TYROSINE PHOSPHATASE 1B; RECOMBINANT HUMAN INSULIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; COMBUSTION; CONTROLLED STUDY; DIET; ENERGY; ENZYME ACTIVITY; FATTY ACID OXIDATION; FEEDING; GENE TARGETING; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIVER; LONG TERM CARE; MALE; MODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SKELETAL MUSCLE; STIMULATION; TISSUE LEVEL; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPONECTIN; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CALORIC RESTRICTION; GENE EXPRESSION REGULATION; INSULIN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MALE; MUSCLE, SKELETAL; PANCREAS; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; RATS; RATS, INBRED F344; SIGNAL TRANSDUCTION; TRIGLYCERIDES; TYROSINE;

ANIMALIA; PRIMATES; RODENTIA;

EID: 3242720519     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2004.03.024     Document Type: Article

References (46)

1. Aoyama T., Peters J.M., Iritani N., Nakajima T., Furihata K., Hashimoto T., Gonzalez F.J. Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J. Biol. Chem. 273:1998;5678-5684
2. Berg A.H., Combs T.P., Du X., Brownlee M., Scherer P.E. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat. Med. 7:2001;947-953
3. Bligh E.G., Dyer W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:1959;911-917
4. Bluher M., Michael M.D., Peroni O.D., Ueki K., Carter N., Kahn B.B., Kahn C.R. Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. Dev. Cell. 3:2002;25-38
5. Bluher M., Kahn B.B., Kahn C.R. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science. 299:2003;572-574
6. Combs T.P., Berg A.H., Obici S., Scherer P.E., Rossetti L. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J. Clin. Invest. 108:2001;1875-1881
7. Combs T.P., Wagner J.A., Berger J., Doebber T., Wang W.J., Zhang B.B., Tanen M., Berg A.H., O'Rahilly S., Savage D.B., Chatterjee K., Weiss S., Larson P.J., Gottesdiener K.M., Gertz B.J., Charron M.J., Scherer P.E., Moller D.E. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology. 143:2002;998-1007
8. Desvergne B., Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev. 20:1999;649-688
9. Elchebly M., Payette P., Michaliszyn E., Cromlish W., Collins S.A., Himms-Hagen J., Chan C.C., Ramachandran C., Gresser M.J., Tremblay M.L., Kennedy B.P. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Science. 283:1999;1544-1548
10. Fruebis J., Tsao T.S., Javorschi S., Ebbets-Reed D., Erickson M.R., Yen F.T., Bihain B.E., Lodish H.F. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc. Natl Acad. Sci. USA. 98:2001;2005-2010
11. Hansen B.C., Bodkin N.L. Primary prevention of diabetes mellitus by prevention of obesity in monkeys. Diabetes. 42:1993;1809-1814
12. Havel P.J. Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin. Curr. Opin. Lipidol. 13:2002;51-59
13. Hotamisligil G.S., Shargill N.S., Spiegelman B.M. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 259:1993;87-91
14. Hotta K., Funahashi T., Bodkin N.L., Ortmeyer H.K., Arita Y., Hansen B.C., Matsuzawa Y. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes. 50:2001;1126-1133
15. Kahn B.B., Flier J.S. Obesity and insulin resistance. J. Clin. Invest. 106:2000;473-481
16. Kaplan F., Al-Majali K., Betteridge D.J. PPARS, insulin resistance and type 2 diabetes. J. Cardiovasc. Risk. 8:2001;211-217
17. Kemnitz J.W., Roecker E.B., Weindruch R., Elson D.F., Baum S.T., Bergman R.N. Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. Am. J. Physiol. 266:1994;E540-E547
18. Kennedy B.P., Ramachandran C. Protein tyrosine phosphatase-1B in diabetes. Biochem. Pharmacol. 60:2000;877-883
19. Kersten S., Desvergne B., Wahli W. Roles of PPARs in health and disease. Nature. 405:2000;421-424
20. Kissebah A.H., Sonnenberg G.E., Myklebust J., Goldstein M., Broman K., James R.G., Marks J.A., Krakower G.R., Jacob H.J., Weber J., Martin L., Blangero J., Comuzzie A.G. Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc. Natl Acad. Sci. USA. 97:2000;14478-14483
21. Klaman L.D., Boss O., Peroni O.D., Kim J.K., Martino J.L., Zabolotny J.M., Moghal N., Lubkin M., Kim Y.B., Sharpe A.H., Stricker-Krongrad A., Shulman G.I., Neel B.G., Kahn B.B. Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Mol. Cell. Biol. 20:2000;5479-5489
22. Krakoff J., Funahashi T., Stehouwer C.D., Schalkwijk C.G., Tanaka S., Matsuzawa Y., Kobes S., Tataranni P.A., Hanson R.L., Knowler W.C., Lindsay R.S. Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian. Diabetes Care. 26:2003;1745-1751
23. Leone T.C., Weinheimer C.J., Kelly D.P. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc. Natl Acad. Sci. USA. 96:1999;7473-7478
24. Lindsay R.S., Funahashi T., Hanson R.L., Matsuzawa Y., Tanaka S., Tataranni P.A., Knowler W.C., Krakoff J. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet. 360:2002;57-58
25. Luke A., Wu X., Zhu X., Kan D., Su Y., Cooper R. Linkage for BMI at 3q27 region confirmed in an African-American population. Diabetes. 52:2003;1284-1287
26. Maeda N., Takahashi M., Funahashi T., Kihara S., Nishizawa H., Kishida K., Nagaretani H., Matsuda M., Komuro R., Ouchi N., Kuriyama H., Hotta K., Nakamura T., Shimomura I., Matsuzawa Y. PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes. 50:2001;2094-2099
27. Masoro E.J. Caloric restriction and aging: an update. Exp. Gerontol. 35:2000;299-305
28. Matsuzawa Y., Funahashi T., Nakamura T. Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann. N. Y. Acad. Sci. 18:1999;146-154
29. Nadiv O., Shinitzky M., Manu H., Hecht D., Roberts C.T. Jr., LeRoith D., Zick Y. Elevated protein tyrosine phosphatase activity and increased membrane viscosity are associated with impaired activation of the insulin receptor kinase in old rats. Biochem. J. 298:1994;443-450
30. Nadler S.T., Stoehr J.P., Schueler K.L., Tanimoto G., Yandell B.S., Attie A.D. The expression of adipogenic genes is decreased in obesity and diabetes mellitus. Proc. Natl Acad. Sci. USA. 97:2000;11371-11376
31. Okauchi N., Mizuno A., Yoshimoto S., Zhu M., Sano T., Shima K. Is caloric restriction effective in preventing diabetes mellitus in the Otsuka Long Evans Tokushima fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus? Diabetes Res. Clin. Pract. 27:1995;97-106
32. Okuno A., Tamemoto H., Tobe K., Ueki K., Mori Y., Iwamoto K., Umesono K., Akanuma Y., Fujiwara T., Yazaki Y., Kadowaki T. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J. Clin. Invest. 101:1998;1354-1361
33. Reaven G.M. Pathophysiology of insulin resistance in human disease. Physiol. Rev. 75:1995;473-486
34. Reaven E., Wright D., Mondon C.E., Solomon R., Ho H., Reaven G.M. Effect of age and diet on insulin secretion and insulin action in the rat. Diabetes. 32:1983;175-180
35. Rondinone C.M., Trevillyan J.M., Clampit J., Gum R.J., Berg C., Kroeger P., Frost L., Zinker B.A., Reilly R., Ulrich R., Butler M., Monia B.P., Jirousek M.R., Waring J.F. Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesis. Diabetes. 51:2002;2405-2411
36. Rosen E.D., Spiegelman B.M. PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J. Biol. Chem. 276:2001;37731-37734
37. Smith S.A. Peroxisome proliferator-activated receptors and the regulation of mammalian lipid metabolism. Biochem. Soc. Trans. 30:2001;1086-1090
38. Spiegelman B.M. PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes. 47:1998;507-514
39. Steppan C.M., Bailey S.T., Bhat S., Brown E.J., Banerjee R.R., Wright C.M., Patel H.R., Ahima R.S., Lazar M.A. The hormone resistin links obesity to diabetes. Nature. 409:2001;307-312
40. Stefan N., Vozarova B., Funahashi T., Matsuzawa Y., Weyer C., Lindsay R.S., Youngren J.F., Havel P.J., Pratley R.E., Bogardus C., Tataranni P.A. Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. Diabetes. 51:2002;1884-1884
41. Uchimura K., Nakamuta M., Enjoji M., Irie T., Sugimoto R., Muta T., Iwamoto H., Nawata H. Activation of retinoic X receptor and peroxisome proliferator-activated receptor-gamma inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells. Hepatology. 33:2001;91-99
42. Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., Mori Y., Murakami K., Tsuboyama-Kasaoka N., Ezaki O., Akanuma Y., Gavrilova O., Vinson C., Reitman M.L., Kagechika H., Shudo K., Yoda M., Nakano Y., Tobe K., Nagai R., Kimura S., Tomita M., Froguel P., Kadowaki T. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7:2001;941-946
43. Yang W.S., Jeng C.Y., Wu T.J., Tanaka S., Funahashi T., Matsuzawa Y., Wang J.P., Chen C.L., Tai T.Y., Chuang L.M. Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care. 25:2002;376-380
44. Ye J.M., Iglesias M.A., Watson D.G., Ellis B., Wood L., Jensen P.B., Sorensen R.V., Larsen P.J., Cooney G.J., Wassermann K., Kraegen E.W. PPARalpha/gamma ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly. Am. J. Physiol. Endocrinol. Metab. 284:2003;E531-E540
45. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature. 372:1994;425-432
46. Zinker B.A., Rondinone C.M., Trevillyan J.M., Gum R.J., Clampit J.E., Waring J.F., Xie N., Wilcox D., Jacobson P., Frost L., Kroeger P.E., Reilly R.M., Koterski S., Opgenorth T.J., Ulrich R.G., Crosby S., Butler M., Murray S.F., McKay R.A., Bhanot S., Monia B.P., Jirousek M.R. PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice. Proc. Natl Acad. Sci. USA. 99:2002;11357-11362