Chapter XII The Egr transcription factors and their utility in mapping brain functioning

Handbook of Chemical Neuroanatomy

Volumn 19, Issue , 2002, Pages 309-328

  Leah, John ^a   Wilce, Peter A ^b  

^a GRIFFITH UNIVERSITY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

2 amino phosphono valeric acid; 2 APV; activatory protein 1; AP 1; c Jun N terminal kinase; Ca2+ cAMP responsive element, gene regulatory sequence; cAMP; caudomedial neostriatum of the telencephalon; CRE; cyclic adenosinomonophosphate; EGF; Egr response element; epidermal growth factor; EPSP; ERE; ETS; excitatory postsynaptic potential; Fas ligand; FasL; inducible transcription factor; ITF; JNK; long term potentiation; LTP; MAPK; mitogen activated protein kinases; N methyl d aspartate; NCM; nerve growth factor; NF B; NGF; NMDA; nuclear factor B, transcription factor; PKA; protein kinase A; serum responsive element; SRE; tetradecyl phorbol 13 acetate; tetrodotoxin; TNF; TPA; transcription factor; TTX; tumor necrosis factor

Indexed keywords

EID: 3242694670     PISSN: 09248196     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0924-8196(02)80023-9     Document Type: Article

References (129)

1. Aicher W.K., Dinkel A., Grimbacher B., Haas C., Seydlitz-Kurzbach E.V., Peter H.H., and Eibel H. Serum response elements activate and cAMP responsive elements inhibit expression of transcription factor Egr-1 in synovial fibroblasts of rheumatoid arthritis patients. Int Immunol 11 (1999) 47-61
2. Aicher W.K., Sakamoto K.M., Hack A., and Eibel H. Analysis of functional elements in the human Egr-1 gene promoter. Rheumatol Int 18 (1999) 207-214
3. Alonso R., Gnanadicom H., Frechin N., Fournier M., Le Fur G., and Soubrie P. Blockade of neurotensin receptors suppresses the dopamine D1/D2 synergism on immediate early gene expression in the rat brain. Eur J Neurosci 11 (1999) 967-974
4. Barroso I., and Stantisteban P. Insulin-induced early growth response gene (Egr-1): mediates a short term repression of rat malic enzyme gene transcription. J Biol Chem 274 (1999) 17997-18004
5. Beckmann A.M., and Wilce P.A. Egr transcription factors in the nervous system. Neurochem Int 31 (1997) 477-510
6. Berg J.M. Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins. Proc Natl Acad Sci USA 85 (1988) 99-102
7. Berger P., Kozlov S.V., Cinelli P., Kruger S.R., Vogt L., and Sonderegger P. Neuronal depolarization enhances the transcription of the neuronal serine protease inhibitor neuroserpin. Mol Cell Neurosci 14 (1999) 455-467
8. Bolhuis J.J., Zijlstra G.G., den Boer-Visser A.M., and Van Der Zee E.A. Localized neuronal activation in the zebra finch brain is related to the strength of song learning. Proc Natl Acad Sci USA 97 (2000) 2282-2285
9. Bon K., Lanteri-Minet M., Michiels J.F., and Menetrey D. Cyclophosphamide cystitis as a model of visceral pain in rats: A c-fos and Krox-24 study at telencephalic levels, with a note on pituitary adenylate cyclase activating polypeptide (PACAP). Exp Brain Res 122 (1998) 165-174
10. Borday V., Kato F., and Champagnat J. A ventral pontine pathway promotes rhythmic activity in the medulla of neonatal mice. Neuroreport 8 (1997) 3679-3683
11. Brennan P.A., Schellinck H.M., and Keverne E.B. Patterns of expression of the immediate-early gene egr-1 in the accessory olfactory bulb of female mice exposed to pheromonal constituents of male urine. Neuroscience 90 (1999) 1460-1463
12. Brinton R.D., Yamazaki R., Gonzalez C.M., O'Neill K., and Schreiber S.S. Vasopressin-induction of the immediate early gene, NGFI-A, in cultured hippocampal glial cells. Mol Brain Res 57 (1998) 73-85
13. Caleo M., Lodovichi C., Pizzorusso T., and Maffei L. Expression of the transcription factor Zif268 in the visual cortex of monocularly deprived rats, effects of nerve growth factor. Neuroscience 91 (1999) 1017-1026
14. Carrasco-Serrano C., Viniegra S., Ballesta J.J., and Criado M. Phorbol ester activation of the nicotinic acetylcholine receptor alpha7 subunit gene, involvement of transcription factor Egr-1. J Neurochem 74 (2000) 932-939
15. Chapman N.R., and Perkins N.D. Inhibition of the RelA(p65): NF-kappaB subunit by Egr-1. J Biol Chem 275 (2000) 4719-4725
16. Chaudhuri A., and Cynader M.S. Activity-dependent expression of the transcription factor Zif268 reveals ocular dominance columns in monkey visual cortex. Brain Res 605 (1993) 349-353
17. Chaudhuri A., Matsubara J.A., and Cynader M.S. Neuronal activity in primate visual cortex assessed by immunostaining for the transcription factor Zif268. Vis Neurosci 12 (1995) 35-45
18. Chavrier P., Janssen-Timmen U., Mattei M.G., Zerial M., Bravo R., and Charnay P. Nucleotide structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos. Mol Cell Biol 9 (1988) 787-797
19. Chergui K., Svenningsson P., Nomikos G.G., Gondon F., Fredholm B.B., and Svennson T.H. Increased expression of NGFI-A mRNA in the rat striatum following stimulation of the medial forebrain bundle. Eur J Neurosci 9 (1997) 2370-2382
20. Chiu J.J., Wung B.S., Hsieh H.J., Lo L.W., and Wang D.L. Nitric oxide regulates shear stress-induced early growth response-1 expression via the extracellular signal-regulated kinase pathway in endothelial cells. Circ Res 85 (1999) 238-246
21. Cochran B.H. Regulation of immediate early gene expression. NIDA Res Monogr 125 (1993) 3-24
22. Condorelli D.F., Dell'Albani P., Amico C., Kaczmarek L., Nicoletti F., Lukasiuk K., and Stella A.M. Induction of primary response genes by excitatory amino acid receptor agonists in primary astroglial cultures. J Neurochem 60 (1993) 877-885
23. Cosgaya J.M., Perez-Juste G., and Aranda A. Retinoic acid regulates selectively the expression of immediate early response genes in PC12 cells. FEBS Lett 429 (1998) 254-258
24. Crino P., Khodakhah K., Becker K., Ginsberg S., Hemby S., and Erbwine J. Presence and phosphorylation of transcription factors in developing dendrites. Proc Natl Acad Sci USA 95 (1998) 2313-2318
25. Davis S., Vanhoutte P., Pages C., Caboche J., and Laroche S. The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo. J Neurosci 20 (2000) 4563-4572
26. DeFranco C., Damon D.H., Endoh M., and Wagner J.A. Nerve growth factor induces transcription of NGFI-A through complex regulatory elements that are also sensitive to serum and phorbol 12-myristate 13-acetate. Mol Endocrinol 7 (1993) 365-379
27. Demmer J., Dragunow M., Lawlor P.A., Mason S.E., Leah J.D., Abraham W.C., and Tate W.P. Differential expression of immediate early genes after hippocampal long-term potentiation in awake rats. Mol Brain Res 17 (1993) 279-286
28. Depaz I.M., Goodenough S., and Wilce P.A. Chronic ethanol has region-selective effects on Egr-1 and Egr-3 DNA-binding activity and protein expression in the rat brain. Neurochem Int 37 (2000) 473-482
29. Dragunow M., and Hughes P. Differential expression of immediate-early proteins in non-nerve cells after focal brain injury. Int J Neurosci 11 (1993) 249-255
30. Di Battista J.A., and Martel-Pelletier J. Suppression of tumor necrosis factor (TNF-alpha): gene expression by prostaglandin E(2): role of early growth response protein-1 (Egr-1). Osteoarthritis Cartilage 7 (1999) 395-398
31. Enslen H., and Soderling T.R. Roles of calmodulin-dependent protein kinases and phosphatase in calcium-dependent transcription of immediate early genes. J Biol Chem 269 (1994) 20872-20877
32. Fordyce D.E., Bhat R.V., Baraban J.M., and Wehner J.M. Genetic and activity-dependent regulation of zif268 expression: association with spatial learning. Hippocampus 4 (1994) 559-568
33. Gass P., Herdegen T., Bravo R., and Kiessling M. Induction and suppression of immediate early genes (IEGs) in specific rat brain regions by the non-competitive NMDA receptor antagonist MK-801. Neuroscience 53 (1993) 749-758
34. 14C]deoxyglucose metabolism. Mol Brain Res 46 (1997) 177-184
35. Herdegen T., and Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system, control of gene expression by Jun Fos and Krox and CREB/ATF proteins. Brain Res Rev 28 (1998) 370-490
36. Herdegen T., Kiessling M., Bele S., Bravo R., Zimmermann M., and Gass P. The KROX-20 transcription factor in the rat central and peripheral nervous systems, novel expression pattern of an immediate early gene-encoded protein. Neuroscience 57 (1993) 41-52
37. Hodge C., Liao J., Stofega M., Guan K., Carter-Su C., and Schwartz J. Growth hormone stimulates phosphorylation and activation of elk-1 and expression of c-fos egr-1 and junB through activation of extracellular signal-regulated kinases 1 and 2. J Biol Chem 273 (1998) 31327-31336
38. Holst C., Skerka C., Lichter P., Bialonski A., and Zipfel P.F. Genomic organization, chromosomal localization and promoter function of the human zinc-finger gene pAT133. Hum Mol Genet 2 (1993) 367-372
39. Honkaniemi J., and Sharp F.R. Prolonged expression of zinc finger immediate-early gene mRNAs and decreased protein synthesis following kainic acid induced seizures. Eur J Neurosci 11 (1999) 10-17
40. Hosono S., Gross I., English M.A., Hajra K.M., Fearon E.R., and Licht J.D. E-cadherin is a WT1 target gene. J Biol Chem 275 (2000) 10943-10953
41. Hughes P.E., Young D., Preston K.M., Yan Q., and Dragunow M. Differential regulation by MK801 of immediate-early genes, brain-derived neurotrophic factor and trk receptor mRNA induced by a kindling after-discharge. Mol Brain Res 53 (1998) 138-151
42. Hughes P.E., Alexi T., Walton M., Williams C.E., Dragunow M., Clarke R.G., and Gluckman P.D. Activity and injury-dependent expression of inducible transcription factors, growth factors and apoptosis-related genes within the central nervous system. Prog Neurobiol 57 (1999) 421-450
43. Humblot N., Thiriet N., Gobaille S., Aunis D., and Zwiller J. The serotonergic system modulates the cocaine-induced expression of the immediate early genes egr-1 and c-fos in rat brain. Ann NY Acad Sci 844 (1998) 7-20
44. Hung A.C., Huang H.M., Tsay H.J., Lin T.N., Kuo J.S., and Sun S.H. ATP-stimulated c-fos and zif268 mRNA expression is inhibited by chemical hypoxia in a rat brain-derived type 2 astrocyte cell line RBA-2. J Cell Biochem 77 (2000) 323-332
45. Hunt S.P., Pini A., and Evan G. Induction of c-fos-like protein in spinal neurons following sensory stimulation. Nature 328 (1987) 632-634
46. Jarvis E.D., and Mello C.V. Molecular mapping of brain areas involved in parrot vocal communication. J Comp Neurol 419 (2000) 1-31
47. Jarvis E.D., Schaff C., Grossman M.R., Ramos J.A., and Nottebohm F. For whom the bird sings, context-dependent gene expression. Neuron 21 (1998) 775-788
48. Jarvis E.D., Ribeiro S., da Silva M.L., Ventura D., Vielliard J., and Mello C.V. Behaviourally driven gene expression reveals song nuclei in hummingbird brain. Nature 406 (2000) 628-632
49. Jin H., and Clayton D.F. Localized changes in immediate-early gene regulation during sensory and motor learning in zebra finches. Neuron 19 (1997) 1049-1059
50. Jin Y., Sheikh F., Detillieux K.A., and Cattini P.A. Role for early growth response-1 protein in alpha(1)-adrenergic stimulation of fibroblast growth factor-2 promoter activity in cardiac myocytes. Mol Pharmacol 57 (2000) 984-990
51. Johansson I.M., Bjartmar L., Marcusson J., Ross S.B., Seckl J.R., and Olsson T. Chronic amitriptyline treatment induces hippocampal NGFI-A glucocorticoid receptor and mineralocorticoid receptor mRNA expression in rats. Mol Brain Res 62 (1998) 92-95
52. Joseph L.J., Le Beau M.M., Jamieson G.A., Acharya S., Shows T.B., Rowley J.D., and Sukhatme V.P. Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with zinc-finger binding structure. Proc Natl Acad Sci USA 85 (1988) 7164-7168
53. Kaczmarek L., Zangenehpour S., and Chaudhuri A. Sensory regulation of immediate-early genes c-fos and zif268 in monkey visual cortex at birth and throughout the critical period. Cereb Cortex 9 (1999) 179-187
54. Kendall G., Ensor E., Brar-Rai A., Winter J., and Latchman D.S. Nerve growth factor induces expression of immediate-early genes NGFI-A (Egr-1) and NGFI-B (nur77) in adult dorsal root ganglion neurons. Mol Brain Res 25 (1994) 73-79
55. Kenneth J.M., and Mack P.A. Induction of transcription factors in somatosensory cortex after tactile stimulation. Mol Brain Res 12 (1992) 141-147
56. Khan S.M., Smith T.S., and Bennett J.P. Effects of single and multiple treatments with l-dihydroxyphenylalanine (l-DOPA): on dopamine receptor-G protein interactions and supersensitive immediate early gene responses in striata of rats after reserpine treatment or with unilateral nigrostriatal lesions. J Neurosci Res 55 (1999) 71-79
57. Kharbanda S., Nakamura T., Stone R., Hass R., Bernstein S., Datta Sukhatme V.P., and Kufe D. Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation. J Clin Invest 88 (1991) 571-577
58. Kim S.J., Park K., Rudkin B.B., Dey B.R., Sporn M.B., and Roberts A.B. Nerve growth factor induces transcription of transforming growth factor-beta1 through a specific promoter element in PC12 cells. J Biol Chem 269 (1994) 3739-3744
59. Koganemaru M., Takasaki M., and Nishimori T. Simultaneous activation of N-methyl-d-aspartate and neurokinin-1 receptors modulates c-Fos and Zif/268 expression in the rat trigeminal nucleus caudalis. Neuroscience 98 (2000) 317-323
60. Kumahara E., Ebihara T., and Saffen D. Nerve growth factor induces zif268 gene expression via MAPK-dependent and -independent pathways in PC12 cells. J Biochem (Tokyo) 125 (1999) 541-553
61. Kuzmin A., and Johansson B. Expression of c-fos, NGFI-A and secretogranin II mRNA in brain regions during initiation of cocaine self-administration in mice. Eur J Neurosci 11 (1999) 3694-3700
62. Lanteri-Minet M., Isnardon P., De Pommery J., and Menetrey D. Spinal and hindbrain structures involved in visceroception and visceronociception as revealed by the expression of Fos, Jun and Krox-24 proteins. Neuroscience 55 (1993) 737-753
63. Lanteri-Minet M., Bon K., de Pommery J., Michiels J.F., and Menetrey D. Cyclophosphamide cystitis as a model of visceral pain in rats: model elaboration and spinal structures involved as revealed by the expression of c-Fos and Krox-24 proteins. Exp Brain Res 105 (1995) 220-232
64. Leveque J.C., Macias W., Rajadhyaksha A., Carlson R.R., Barczak A., Kang S., Li X.M., Coyle J.T., Huganir R.L., Heckers S., and Konradi C. Intracellular modulation of NMDA receptor function by antipsychotic drugs. J Neurosci 20 (2000) 4011-4020
65. Liu C., Yao J., Mercola D., and Adamson E. The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251. J Biol Chem 257 (2000) 20315-20323
66. Luckman S.M. Comparison of the expression of c-fos, nur77 and egr1 mRNA in rat hypothalamic magnocellular neurons and their putative afferent projection neurons: cell- and stimulus-specific induction. Eur J Neurosci 9 (1997) 2443-2451
67. Mack K.J., Cortner J., Mack P., and Farnham P.J. Krox-20 messenger RNA and protein expression in the adult central nervous system. Mol Brain Res 14 (1992) 117-123
68. Mack K.J., Yi S.D., Chang S., Millan N., and Mack P. NGF1-C expression is affected by physiological stimulation and seizures in the somatosensory cortex. Mol Brain Res 29 (1995) 140-146
69. Malkani S., and Rosen J.B. Specific induction of early growth response gene 1 in the lateral nucleus of the amygdala following contextual fear conditioning in rats. Neuroscience 97 (2000) 693-702
70. Matsumoto T., Akiama N., Kizaka-Kondoh S., and Noda M. Transient over-expression of NGFI-A gene suppresses NGF-induced neurite outgrowth in PC12 cells. Neuroreport 11 (2000) 1001-1005
71. Matheny C., Day M.L., and Milbrandt J. The nuclear localization signal of NGFI-A is located within the zinc finger DNA binding domain. J Biol Chem 269 (1994) 8176-8181
72. McKitrick D.J., Krukoff T.L., and Calaresu F.R. Expression of c-fos protein in rat brain after electrical stimulation of the aortic depressor nerve. Brain Res 599 (1992) 215-222
73. Mechta F., Piette J., Hirai S.-I., and Yaniv M. Stimulation of protein kinase C or protein kinase A mediated signal transduction pathways shows three modes of response among serum inducible genes. New Biol 3 (1989) 297-304
74. Mello C.V., and Ribeiro S. ZENK protein regulation by song in the brain of songbirds. J Comp Neurol 393 (1998) 426-438
75. Melzer P., and Steiner H. Stimulus-dependent expression of immediate-early genes in rat somatosensory cortex. J Comp Neurol 380 (1997) 145-153
76. Milbrandt J. A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. Science 238 (1987) 797-799
77. Miller J., McLachlan A.D., and Klug A. Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J 4 (1985) 1609-1614
78. Miyashita Y., Morita M., Naya Y., Yoshida M., and Tomita H. Backward signal from medial temporal lobe in neural circuit reorganization of primate inferotemporal cortex. Czech Repub Acad Sci III 321 (1998) 185-192
79. Mora-Garcia P., and Sakamoto K.M. Granulocyte colony-stimulating factor induces Egr-1 up-regulation through interaction of serum response element-binding proteins. J Biol Chem 275 (2000) 22418-22426
80. Morgan J.I., Cohen D.R., Hempstead J.L., and Curran T. Mapping patterns of c-fos expression in the central nervous system after seizure. Science 237 (1987) 192-197
81. Morris M.E., Viswanathan N., Kuhlman S., Davis F.C., and Weitz C.J. A screen for genes induced in the suprachiasmatic nucleus by light. Science 279 (1998) 1544-1547
82. Nahm W.K., and Noebels J.L. Non obligate role of early or sustained expression of immediate-early gene proteins c-fos, c-jun, and zif/268 in hippocampal mossy fiber sprouting. J Neurosci 18 (1998) 9245-9255
83. Nikam S.S., Tennekoon G.I., Christy B.A., Yoshino J.E., and Rutkowski J.L. The zinc finger transcription factor Zif268/Egr-1 is essential for Schwann cell expression of the p75 NGF receptor. Mol Cell Biol 6 (1995) 337-348
84. Nikolaev E., Werka T., and Kaczmarek L. c-fos protooncogene expression in rat brain after long-term training of two-way active avoidance reaction. Behav Brain Res 48 (1992) 91-94
85. O'Donovan K.J., and Baraban J.M. Major Egr-3 isoforms are generated via alternate translation start sites and differ in their abilities to activate transcription. Mol Cell Biol 19 (1999) 4711-4718
86. O'Donovan K.J., Wilkens E.P., and Baraban J.M. Sequential expression of Egr-1 and Egr-3 in hippocampal granule cells following electroconvulsive stimulation. J Neurochem 70 (1998) 1241-1248
87. O'Donovan K.J., Tourtellotte W.G., Milbrandt J., and Barbaran J.M. The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience. Neurosci 22 (1999) 167-173
88. O'Donovan K.J., Levkovitz Y., Ahn D., and Baraban J.M. Functional comparison of egr-3 transcription factor isoforms, identification of an activation domain in the N-terminal segment absent from egr3beta, a major isoform expressed in brain. J Neurochem 75 (2000) 1352-1357
89. Okuno H., and Miyashita Y. Expression of the transcription factor zif268 in the temporal cortex of monkeys during visual paired associate learning. Eur J Neurosci 8 (1996) 2118-2128
90. Park J.A., and Koh J.Y. Induction of an immediate early gene egr-1 by zinc through extracellular signal-regulated kinase activation in cortical culture, its role in zinc-induced neuronal death. J Neurochem 73 (1999) 450-456
91. Pearse D.D., and Leah J.D. Jun Fos and Krox in the hippocampus after C-fiber stimulation: simultaneous-input-dependent expression and nuclear speckling. Brain Res 894 (2001) 193-208
92. Pignatelli M., Cortes-Canteli M., Santos A., and Perez-Castillo A. Involvement of the NGFI-A gene in the differentiation of neuroblastoma cells. FEBS Lett 461 (1999) 37-42
93. Pipaon C., Tsai S.Y., and Tsai M.J. COUP-TF upregulates NGFI-A gene expression through an Sp1 binding site. Mol Cell Biol 19 (1999) 2734-2745
94. Pompeiano M., Cirelli C., Ronca-Testoni S., and Tononi G. NGFI-A expression in the rat brain after sleep deprivation. Mol Brain Res 46 (1997) 143-153
95. Presley R.W., Menetrey D., Levine J.D., and Basbaum A.I. Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord. J Neurosci 10 (1990) 323-335
96. Rengarajan J., Mittelstad P.R., Mages H.W., Gerth A.J., Kroczek R.A., Ashwell J.D., and Glimmer L.H. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity 12 (2000) 293-300
97. Ribeiro S., Cecchi G.A., Magnasco M.O., and Mello C.V. Toward a song code: evidence for a syllabic representation in the canary brain. Neuron 21 (1998) 359-371
98. Ribeiro S., Goyal V., Mello C.V., and Pavlides C. Brain gene expression during REM sleep depends on prior waking experience. Learn Mem 6 (1999) 500-508
99. Sachs A.B., Sarnow P., and Hentze M.W. Starting at the beginning, middle and end, translation initiation in eukaryotes. Cell 89 (1997) 831-838
100. Sato K., Ishikawa K., Ui M., and Okajima F. Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells. Mol Brain Res 74 (1999) 182-189
101. Schwachtgen J.L., Campbell C.J., and Braddock M. Full promoter sequence of human early growth response factor-1 (Egr-1), demonstration of a fifth functional serum response element. DNA Seq 10 (2000) 429-432
102. Seitanidou T., Schneider-Maunoury S., Desmarquet C., Wilkinson D.G., and Charnay P. Krox-20 is a key regulator of rhombomere-specific gene expression in the developing hindbrain. Mech Dev 65 (1997) 31-42
103. Sgambato V., Pages C., Rogard M., Besson J.M., and Caboche J. Extracellular signal-regulated kinase (ERK): controls immediate early gene induction on corticostriatal stimulation. J Neurosci 18 (1998) 8814-8825
104. Sgambato V., Maurice N., Besson J.M., Thierry A.M., and Deniau J.M. Effect of functional impairment of corticostriatal transmission on a cortically evoked expression of c-Fos and zif268 in the rat basal ganglia. Neuroscience 93 (1999) 1313-1321
105. Shirayama Y., Hashimoto K., Matsuki H., Tsunashima K., Iyo M., Higuchi T., and Minabe Y. Increased expression of zif268 mRNA in rat retrosplenial cortex following administration of phencyclidine. Brain Res 839 (1999) 180-185
106. Silverman E.S., Du J., Williams A.J., Wadgaonkar R., Drazen J.M., and Collins T. cAMP-responsive-element-binding-protein binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1). Biochem J 336 (1998) 183-189
107. Slade J.P., and Carter D.A. Cyclic expression of egr-1/NGFI-A in the rat anterior pituitary, a molecular signal for ovulation?. J Neuroendocrinol 12 (2000) 671-676
108. Spencer J.A., and Misra R.P. Expression of the SRF gene occurs through a Ras/Sp/SRF-mediated-mechanism in response to serum growth signals. Oncogene 18 (1999) 7319-7327
109. Steiner H., and Gerfen C.R. Enkephalin regulates acute dopamine receptor antagonist-induced immediate-early gene expression in striatal neurons. Neuroscience 88 (1999) 795-810
110. Stevens B., and Fields R.D. Response of Schwann cells to action potentials in development. Science 287 (2000) 2267-2271
111. Svenningsson P., Nomikos G.G., and Fredholm B.B. The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions. J Neurosci 19 (1999) 4011-4022
112. Sukhatme V.P., Cao X., Chang L.C., Tsai-Morris C.-H., Stamenkovich D., Ferreira P.C.P., Cohen D.R., Edwards S.A., Shows T.B., Curran T., Le Beau M.M., and Adamson E.D. A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell 53 (1988) 37-43
113. Swirnoff A.H., and Milbrandt J. DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Mol Cell Biol. 15 (1995) 2275-2287
114. Tanaka M., Iijima N., Amaya F., Tamada Y., and Ibata Y. NGFI-A gene expression induced in the rat suprachiasmatic nucleus by photic stimulation: spread into hypothalamic periventricular somatostatin neurons and GABA receptor involvement. Eur J Neurosci 11 (1999) 3178-3184
115. Tourtellotte W.G., Nagarajan R., Bartke A., and Milbrandt J. Functional compensation by Egr-4 in Egr-1-dependent luteinizing hormone regulation and Leydig cell steroidogenesis. Mol Cell Biol 20 (2000) 5261-5268
116. Traub R.J., Herdegen T., and Gebhard G.F. Differential expression of c-FOS and c-JUN in two regions of the rat spinal cord following noxious distension. Neurosci Lett 160 (1992) 121-125
117. Tsai J.C., Liu L., Guan J., and Aird W.C. The Egr-1 gene is induced by epidermal growth factor in ECV304 cells and primary endothelial cells. Am J Physiol 279 (2000) 1414-1424
118. Tsai-Morris C.H., Cao X.M., and Sukhatme V.P. Nucleotide 5' flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene. Nucleic Acids Res 16 (1988) 8835-8846
119. Von der Kammer H., Mayhaus M., Albrecht C., Enderich J., Wegner M., and Nitsch R.M. Muscarinic acetylcholine receptors activate expression of the EGR gene family of transcription factors. J Biol Chem 273 (1998) 14538-14544
120. Wang J.Q. Regulation of immediate early gene c-fos and zif/268 mRNA expression in rat striatum by metabotropic glutamate receptor. Mol Brain Res 57 (1998) 46-53
121. Waters C.M., Hancock D.C., and Evan G.I. Identification and characterisation of the egr-1 gene product as an inducible, short-lived, nuclear phosphoprotein. Oncogene 5 (1990) 669-674
122. Wei F., Xu Z.C., Qu Z., Milbrandt J., and Zhuo M. Role of EGR1 in hippocampal synaptic enhancement induced by tetanic stimulation and amputation. J Cell Biol 149 (2000) 1325-1334
123. Wernerson J., Johansson I., Larsson U., Minth-Worby C., Pahlman S., and Andersson G. Activated transcription of the human neuropeptide Y gene in differentiating SH-SY5Y neuroblastoma cells is dependent on transcription factors AP-1, AP-2alpha, and NGFI. J Neurochem 70 (1998) 1887-1897
124. Williams J.M., Beckmann A.M., Mason-Parker S.E., Abraham W.C., Wilce P.A., and Tate W.P. Sequential increase in Egr-1 and AP-1 DNA binding activity in the dentate gyrus following the induction of long-term potentiation. Mol Brain Res 77 (2000) 258-266
125. Worley P.F., Christy B.A., Nakabeppu Y., Bhat R.V., Cole A.J., and Baraban J.M. Constitutive expression of zif268 in neocortex is regulated by synaptic activity. Proc Natl Acad Sci USA 88 (1991) 5106-5110
126. Worley P.F., Bhat R.V., Baraban J.M., Erickson C.A., McNaughton B.L., and Barnes C.A. Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement. J Neurosci 13 (1993) 4776-4786
127. Xiao S., Matsui K., Fine A., Zhu B., Marshak-Rothstein A., Widom R.L., and Ju S.T. FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3. Eur J Immunol 29 (1999) 3456-3465
128. Zhang F., Vanduffel W., Schiffmann S.N., Mailleux P., Arckens L., Vandesande F., Orban G.A., and Vanderhaeghen J.-J. Decrease of zif-268 and c-fos and increase of c-jun mRNA in the cat areas 17, 18 and 19 following complete visual deafferentation. Eur J Neurosci 7 (1995) 1292-1296
129. Zipfel P.F., Decker E.L., Holst C., and Sherka C. The human zinc finger protein EGR-4 acts as autoregulatory transcriptional repressor. Biochim Biophys Acta 1354 (1997) 134-144