Activated transcription of the human neuropeptide Y gene in differentiating SH-SY5Y neuroblastoma cells is dependent on transcription factors AP-1, AP-2α, and NGFI

Journal of Neurochemistry

Volumn 70, Issue 5, 1998, Pages 1887-1897

  Wernersson, Jonny ^b,c   Johansson, Irja ^a,c   Larsson, Ulrika ^a   Minth Worby, Carolyn ^d   Påhlman, Sven ^c   Andersson, Göran ^b  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

AP 1; AP 2 ; Neuropeptide Y; NGFI; SH SY5Y neuroblastoma; Transcription

Indexed keywords

NERVE GROWTH FACTOR; NEUROPEPTIDE Y; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR AP 2;

ARTICLE; CELL DIFFERENTIATION; DRUG RECEPTOR BINDING; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROCESSING; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; SYMPATHETIC NERVE CELL; TRANSCRIPTION REGULATION;

EID: 0031956258     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70051887.x     Document Type: Article

References (42)

1. Allen J. M., Martin J. B., and Heinrich G. (1987) Neuropeptide Y gene expression in PC12 cells and its regulation by nerve growth factor: a model for developmental regulation. Mol. Brain Res. 3, 39-43.
2. Andersson G. and Peterlin B. M. (1990) NF-X2 that binds to the DRA X2-box is activator protein 1: expression cloning of c-Jun. J. Immunol. 145, 3456-3462.
3. Andersson G., Påhlman S., Parrow V., Johansson I., and Hammerling U. (1994) Activation of the human NPY gene during neuroblastoma cell differentiation: induced transcriptional activities of AP-1 and AP-2. Cell Growth Differ. 5, 27-36.
4. Andrews N. C. and Faller D. V. (1991) A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19, 2499.
5. Auffray C. and Rougeon F. (1980) Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur. J. Biochem. 107, 303-314.
6. Azar C. G., Scavarda N. J., Reynolds C. P., and Brodeur G. M. (1990) Multiple defects of the nerve growth factor receptor in human neuroblastoma. Cell Growth Differ. 1, 421-428.
7. Baichwal V. R. and Tjian R. (1990) Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain δ: differences between v- and c-Jun. Cell 63, 815-825.
8. Balbi D. and Allen J. M. (1994) Role of protein kinase C in mediating NGF effect on neuropeptide Y expression in PC12 cells. Brain Res. Mol. Brain Res. 23, 310-316.
9. Biedler J. L., Roffler-Tarlov S., Schachner M., and Freedman L. S. (1978) Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38, 3751-3757.
10. Chen C. and Okayama H. (1987) High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752.
11. Crosby S. D., Puetz J. J., Simburger K. S., Fahrner T. J., and Milbrandt J. (1991) The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family. Mol. Cell. Biol. 11, 3835-3841.
12. Fagerström S., Påhlman S., Gestblom C., and Nånberg E. (1996) Protein kinase C-ε is implicated in neunte outgrowth in differentiating human neuroblastoma cells. Cell Growth Differ. 7, 775-785.
13. Fried M. and Crothers D. M. (1981) Equilibria and kinetics of lac repressor-operator by polyacrylamide gel electrophoresis. Nucleic Acids Res. 9, 6505-6525.
14. Gorman C. M., Merlino G. T., Willingham M. C., Pastan I., and Howard B. H. (1982) The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc. Natl. Acad. Sci. USA 79, 6777-6781.
15. Hammerling U., Bjelfman C., and Påhlman S. (1987) Different regulation of N- and c-Myc during phorbol ester-induced maturation of human SH-SY5Y neuroblastoma cells. Oncogene 2, 73-77.
16. Higuchi H., Yang H. Y., and Sabol S. L. (1988) Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester. J. Biol. Chem. 263, 6288-6295.
17. Higuchi H., Nakano K., and Miki N. (1992) Identification of NGF-response element in the rat neuropeptide Y gene and induction of the binding proteins. Biochem. Biophys. Res. Commun. 189, 1553-1560.
18. 2+- and cyclic AMP/phorbol 12-myristate 13-acetate-responsive elements. J. Neurochem. 66, 1802-1809.
19. Honkaniemi J., Sagar S. M., Pyykoenen I., Hicks K. J., and Sharp F. R. (1995) Focal brain injury induces multiple immediate early genes encoding zinc finger transcription factors. Mol. Brain Res. 28, 157-163.
20. Imagawa M., Chiu R., and Karin M. (1987) Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP. Cell 51, 251-260.
21. Jalava A. and Mai S. (1994) Fos and Jun form cell specific protein complexes at the neuropeptide tyrosine promoter. Oncogene 9, 2369-2375.
22. Lavenius E., Parrow V., Nånberg E., and Påhlman S. (1994) Basic FGF and IGF-I promote differentiation of human SH-SY5Y neuroblastoma cells in culture. Growth Factors 10, 29-39.
23. Lavenius E., Gestblom C., Johansson I., Nånberg E., and Påhlman S. (1995) Transfection of TRK-A into human neuroblastoma cells restores their ability to differentiate in response to nerve growth factor. Cell Growth Differ. 6, 727-736.
24. Lerchen R. A., Yum D.-Y., Krajcik R., and Minth-Worby C. (1995) Transcriptional vs. posttranscriptional control of neuropeptide Y gene expression. Endocrinology 136, 833-841.
25. Lloyd A., Yancheva N., and Wasylyk B. (1991) Transformation suppressor activity of a Jun transcription factor lacking its activation domain. Nature 352, 635-638.
26. Minth C. D. and Dixon J. E. (1990) Expression of the human neuropeptide Y gene. J. Biol. Chem. 265, 12933-12939.
27. Minth C. D., Andrews P. C., and Dixon J. E. (1986) Characterization, sequence, and expression of the cloned human neuropeptide Y gene. J. Biol. Chem. 261, 11974-11979.
28. Minth-Worby C. A. (1994) Transcriptional regulation of the human neuropeptide Y gene by nerve growth factor. J. Biol. Chem. 269, 15460-15468.
29. Påhlman S., Odelstad L., Larsson E., Grotte G., and Nilsson K. (1981) Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoylphorbol-13-acetate. Int. J. Cancer 28, 583-589.
30. Påhlman S., Ruusala A.-I., Abrahamsson L., Mattsson M. E. K., and Esscher T. (1984) Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbol ester-induced differentiation. Cell Differ. 14, 135-144.
31. Påhlman S., Meyerson G., Lindgren E., Schalling M., and Johansson I. (1991) Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation. Proc. Natl. Acad. Sci. USA 88, 9994-9998.
32. Påhlman S., Johansson I., Westermark B., and Nistér M. (1992) Platelet-derived growth factor potentiates phorbol ester-induced neuronal differentiation of human neuroblastoma cells. Cell Growth Differ. 3, 783-790.
33. Påhlman S., Hoehner J. C., Nånberg E., Hedborg F., Fagerström S., Gestblom C., Johansson I., Larsson U., Lavenius E., Örtoft E., and Söderblom H. (1995) Differentiation and survival influences of growth factors in human neuroblastoma. Eur. J. Cancer 31A, 453-458.
34. Parrow V., Nånberg E., Heikkilä J., Hammerling U., and Påhlman S. (1992) Protein kinase C remains functionally active during TPA induced neuronal differentiation of SH-SY5Y neuroblastoma cells. J. Cell. Physiol. 152, 536-544.
35. Sabol S. L. and Higuchi H. (1990) Transcriptional regulation of the neuropeptide Y gene by nerve growth factor: antagonism by glucocorticoids and potentiation by adenosine 3′,5′-monophosphate and phorbol ester. Mol. Endocrinol. 4, 384-392.
36. Shoshan M. C. and Linder S. (1994) Induction of the collagenase phorbol ester response element by staurosporine. J. Cell. Biochem. 55, 496-502.
37. Sompayrac L. M. and Danna K. J. (1981) Efficient infection of monkey cells with DNA of simian virus 40. Proc. Natl. Acad. Sci. USA 78, 7575-7578.
38. Swirnoff A. H. and Milbrandt J. (1995) DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Mol. Cell. Biol. 15, 2275-2287.
39. Toullec D., Pianetti P., Coste H., Bellevergue P., Grand-Perret T., Ajakane M., Baudet V., Boissin P., Boursier E., Loriolle F., Duhamel L., Charon D., and Kirilovsky J. (1991) The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266, 15771-15781.
40. Tsang S. Y., Nakanishi M., and Peterlin B. M. (1988) B-cell-specific and interferon-γ-inducible regulation of the HLA-DRα gene. Proc. Natl. Acad. Sci. USA 85, 8598-8602.
41. Westin G. and Schaffner W. (1988) Heavy metal ions in transcription factors from HeLa cells: Sp1, but not octamer transcription factor requires zinc for DNA binding and for activator function. Nucleic Acids Res. 16, 5771-5781.
42. WAF/CIP1 expression. Nat. Genet. 15, 78-82.