메뉴 건너뛰기




Volumn 125, Issue 3, 1999, Pages 541-553

Nerve growth factor induces zif268 gene expression via MAPK-dependent and -independent pathways in PC12D cells

Author keywords

JNK; MAPK; NGF; Wortmannin; zif268

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE INHIBITOR; WORTMANNIN;

EID: 0032964829     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022319     Document Type: Article
Times cited : (28)

References (86)
  • 1
    • 0029161198 scopus 로고
    • Early growth response protein 1 (Egr-1): Prototype of a zinc-finger family of transcription factors
    • Gashler, A. and Sukhatme, V.P. (1995) Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors. Prog. Nucleic Acid Res. Mol. Biol. 50, 191-224
    • (1995) Prog. Nucleic Acid Res. Mol. Biol. , vol.50 , pp. 191-224
    • Gashler, A.1    Sukhatme, V.P.2
  • 2
    • 0023491356 scopus 로고
    • A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor
    • Milbrandt, J. (1987) A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. Science 238, 797-799
    • (1987) Science , vol.238 , pp. 797-799
    • Milbrandt, J.1
  • 3
    • 0009416244 scopus 로고
    • A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences
    • Christy, B., Lau, L.F., and Nathans, D. (1988) A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences. Proc. Natl. Acad. Sci. USA 85, 7857-7861
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 7857-7861
    • Christy, B.1    Lau, L.F.2    Nathans, D.3
  • 5
    • 0000275078 scopus 로고
    • Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells
    • Lemaire, P., Revelant, O., Bravo, R., and Charnay, P. (1988)Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells. Proc. Natl. Acad. Sci. USA 85, 4691-4695
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4691-4695
    • Lemaire, P.1    Revelant, O.2    Bravo, R.3    Charnay, P.4
  • 6
    • 0026095564 scopus 로고
    • Differential induction of primary-response (TIS) gene in PC12 pheochromocytoma cells and the unresponsive variant PC12nnr5
    • Altin, J.G., Kujubu, D.A., Raffioni, S., Eveleth, D.D., Herschman, H.R., and Bradshaw, R.A. (1991) Differential induction of primary-response (TIS) gene in PC12 pheochromocytoma cells and the unresponsive variant PC12nnr5. J. Biol. Chem. 268, 5401-5406
    • (1991) J. Biol. Chem. , vol.268 , pp. 5401-5406
    • Altin, J.G.1    Kujubu, D.A.2    Raffioni, S.3    Eveleth, D.D.4    Herschman, H.R.5    Bradshaw, R.A.6
  • 7
    • 0026601295 scopus 로고
    • Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts
    • Cao, X.M., Guy, G.R., Sukhatme, V.P., and Tan, Y.H. (1992) Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts. J. Biol. Chem. 267, 1345-1349
    • (1992) J. Biol. Chem. , vol.267 , pp. 1345-1349
    • Cao, X.M.1    Guy, G.R.2    Sukhatme, V.P.3    Tan, Y.H.4
  • 8
    • 0024403534 scopus 로고
    • Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation
    • Cole, A.J., Saffen, D.W., Baraban, J.M., and Worley, P.F. (1989) Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation. Nature 340, 474-476
    • (1989) Nature , vol.340 , pp. 474-476
    • Cole, A.J.1    Saffen, D.W.2    Baraban, J.M.3    Worley, P.F.4
  • 9
    • 0027476589 scopus 로고
    • Additive induction of Egr-1 (zif/268) mRNA expression in neuroblastoma × glioma hybrid NG108-15 cells via cholinergic muscarinic, alpha 2-adrenergic, and bradykinin receptors
    • Katayama, N., Iwata, E., Sakurai, H., Tsuchiya, T., and Tsuda, M. (1993) Additive induction of Egr-1 (zif/268) mRNA expression in neuroblastoma × glioma hybrid NG108-15 cells via cholinergic muscarinic, alpha 2-adrenergic, and bradykinin receptors. J. Neurochem. 60, 902-907
    • (1993) J. Neurochem. , vol.60 , pp. 902-907
    • Katayama, N.1    Iwata, E.2    Sakurai, H.3    Tsuchiya, T.4    Tsuda, M.5
  • 10
    • 0029030483 scopus 로고
    • Induction of c-fos and zif/ 268 gene expression in rat striatal neurons, following stimulation of D1-like dopamine receptors, involves protein kinase A and protein kinase C
    • Simpson, C.S. and Morris, B.J. (1995) Induction of c-fos and zif/ 268 gene expression in rat striatal neurons, following stimulation of D1-like dopamine receptors, involves protein kinase A and protein kinase C. Neuroscience 68, 97-106
    • (1995) Neuroscience , vol.68 , pp. 97-106
    • Simpson, C.S.1    Morris, B.J.2
  • 11
    • 0031037662 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptor-mediated induction of zif268 mRNA in PC12D cells requires protein kinase C and the influx of extracellular calcium
    • Ebihara, T. and Saffen, D. (1997) Muscarinic acetylcholine receptor-mediated induction of zif268 mRNA in PC12D cells requires protein kinase C and the influx of extracellular calcium. J. Neurochem. 68, 1001-1010
    • (1997) J. Neurochem. , vol.68 , pp. 1001-1010
    • Ebihara, T.1    Saffen, D.2
  • 12
    • 0027968663 scopus 로고
    • Roles of calmodulin-dependent protein kinases and phosphatase in calcium-dependent transcription of immediate early genes
    • Enslen, H. and Soderling, T.R. (1994) Roles of calmodulin-dependent protein kinases and phosphatase in calcium-dependent transcription of immediate early genes. J. Biol. Chem. 269, 20872-20877
    • (1994) J. Biol. Chem. , vol.269 , pp. 20872-20877
    • Enslen, H.1    Soderling, T.R.2
  • 13
    • 0032482367 scopus 로고    scopus 로고
    • Stress-induced immediate-early gene, egr-1, involves activation of p38/JNK1
    • Lim, C.P., Jain, N., and Cao, X. (1998) Stress-induced immediate-early gene, egr-1, involves activation of p38/JNK1. Oncogene 16, 2915-2926
    • (1998) Oncogene , vol.16 , pp. 2915-2926
    • Lim, C.P.1    Jain, N.2    Cao, X.3
  • 14
    • 0023511815 scopus 로고
    • Memories of fos
    • Curran, T. and Morgan, J.I. (1987) Memories of fos. Bioessays 7, 255-258
    • (1987) Bioessays , vol.7 , pp. 255-258
    • Curran, T.1    Morgan, J.I.2
  • 15
    • 0026741410 scopus 로고
    • Correlation between the induction of an immediate early gene, zif/268, and long-term potentiation in the dentate gyrus
    • Richardson, C.L., Tate, W.P., Mason, S.E., Lawlar, P.A., Dragunow, M., and Abraham, W.C. (1992) Correlation between the induction of an immediate early gene, zif/268, and long-term potentiation in the dentate gyrus. Brain Res. 580, 147-154
    • (1992) Brain Res. , vol.580 , pp. 147-154
    • Richardson, C.L.1    Tate, W.P.2    Mason, S.E.3    Lawlar, P.A.4    Dragunow, M.5    Abraham, W.C.6
  • 17
    • 0026741410 scopus 로고
    • Correlation between the induction of an immediate early gene, zif/268, and long-term potentiation in the dentate gyrus
    • Richardson, C.L., Tate, W.P., Mason, S.E., Lawlor, P.A., Dragunow, M., and Abraham, W.C. (1992) Correlation between the induction of an immediate early gene, zif/268, and long-term potentiation in the dentate gyrus. Brain Res. 580, 147-154
    • (1992) Brain Res. , vol.580 , pp. 147-154
    • Richardson, C.L.1    Tate, W.P.2    Mason, S.E.3    Lawlor, P.A.4    Dragunow, M.5    Abraham, W.C.6
  • 18
    • 0027443739 scopus 로고
    • Thresholds for synaptic activation of transcription factors in hippocampus: Correlation with long-term enhancement
    • Worley, P.F., Bhat, R.V., Baraban, J.M., Erickson, C.A., McNaughton, B.L., and Barnes, C.A. (1993) Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement. J. Neurosci. 13, 4776-4786
    • (1993) J. Neurosci. , vol.13 , pp. 4776-4786
    • Worley, P.F.1    Bhat, R.V.2    Baraban, J.M.3    Erickson, C.A.4    McNaughton, B.L.5    Barnes, C.A.6
  • 19
    • 0021222306 scopus 로고
    • Anisomycin blocks the late phase of long-term potentiation in the dentate gyrus of freely moving rats
    • Krug, M., Lossner, B., and Ott, T. (1982) Anisomycin blocks the late phase of long-term potentiation in the dentate gyrus of freely moving rats. Brain Res. Bull. 13, 39-42
    • (1982) Brain Res. Bull. , vol.13 , pp. 39-42
    • Krug, M.1    Lossner, B.2    Ott, T.3
  • 20
    • 0023908218 scopus 로고
    • Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro
    • Frey, U., Krug, M., Reymann, K.G., and Matthies, H. (1988) Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro. Brain Res. 452, 57-65
    • (1988) Brain Res. , vol.452 , pp. 57-65
    • Frey, U.1    Krug, M.2    Reymann, K.G.3    Matthies, H.4
  • 21
    • 0024598695 scopus 로고
    • Maintenance of long-term potentiation in rat dentate gyrus requires protein synthesis but not messenger RNA synthesis immediately post-tetanization
    • Otani, S., Marshall, C.J., Tate, W.P., Goddard, G.V., and Abraham, W.C. (1989) Maintenance of long-term potentiation in rat dentate gyrus requires protein synthesis but not messenger RNA synthesis immediately post-tetanization. Neuroscience 28, 519-526
    • (1989) Neuroscience , vol.28 , pp. 519-526
    • Otani, S.1    Marshall, C.J.2    Tate, W.P.3    Goddard, G.V.4    Abraham, W.C.5
  • 22
    • 0028038057 scopus 로고
    • Requirement of a critical period of transcription for induction of a late phase of LTP
    • Nguyen, P.V., Abel, T., and Kandel, E.R. (1994) Requirement of a critical period of transcription for induction of a late phase of LTP. Science 265, 1104-1107
    • (1994) Science , vol.265 , pp. 1104-1107
    • Nguyen, P.V.1    Abel, T.2    Kandel, E.R.3
  • 23
    • 0031024891 scopus 로고    scopus 로고
    • Synaptic tagging and long-term potentiation
    • Frey, U. and Morris, R.G.M. (1997) Synaptic tagging and long-term potentiation. Nature 385, 533-536
    • (1997) Nature , vol.385 , pp. 533-536
    • Frey, U.1    Morris, R.G.M.2
  • 24
    • 0029859835 scopus 로고    scopus 로고
    • Expression of the transcription factor zif268 in the temporal cortex of monkeys during visual paired associate learning
    • Okuno, H. and Miyashita, Y. (1996) Expression of the transcription factor zif268 in the temporal cortex of monkeys during visual paired associate learning. Eur. J. Neurosci. 8, 2118-2128
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 2118-2128
    • Okuno, H.1    Miyashita, Y.2
  • 25
    • 0027394436 scopus 로고
    • Nerve growth factor induces transcription of NGFI-A through complex regulatory elements that are also sensitive to serum and phorbol 12-myristate 13-acetate
    • DeFranco, C., Damon, D.H., Endoh, M., and Wagner, J.A. (1993) Nerve growth factor induces transcription of NGFI-A through complex regulatory elements that are also sensitive to serum and phorbol 12-myristate 13-acetate. Mol. Endocrinol. 7, 365-379
    • (1993) Mol. Endocrinol. , vol.7 , pp. 365-379
    • DeFranco, C.1    Damon, D.H.2    Endoh, M.3    Wagner, J.A.4
  • 26
    • 0023150860 scopus 로고
    • Neuritic growth from a new subline of PC12 pheochromocytoma cells: Cyclic AMP mimics the action of nerve growth factor
    • Katoh-Semba, R., Kitajima, S., Yamazaki, Y., and Sano, M. (1987) Neuritic growth from a new subline of PC12 pheochromocytoma cells: cyclic AMP mimics the action of nerve growth factor. J. Neurosci. Res. 17, 36-44
    • (1987) J. Neurosci. Res. , vol.17 , pp. 36-44
    • Katoh-Semba, R.1    Kitajima, S.2    Yamazaki, Y.3    Sano, M.4
  • 27
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene, L.A. and Tischler, A.S. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 28
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors
    • Segal, R.A. and Greenberg, M.E. (1996) Intracellular signaling pathways activated by neurotrophic factors. Annu. Rev. Neurosci. 19, 463-489
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 463-489
    • Segal, R.A.1    Greenberg, M.E.2
  • 29
    • 0032103332 scopus 로고    scopus 로고
    • Ets transcription factors: Nuclear effectors of the Ras-MAP-kinase signaling pathway
    • Wasylyk, B., Hagman, J., and Gutierrez-Hartmann, A. (1998) Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway. Trends Biol. Sci. 23, 213-216
    • (1998) Trends Biol. Sci. , vol.23 , pp. 213-216
    • Wasylyk, B.1    Hagman, J.2    Gutierrez-Hartmann, A.3
  • 30
    • 0024362535 scopus 로고
    • Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction
    • Herrera, R.E., Shaw, P.E., and Nordheim, A. (1989) Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction. Nature 340, 68-70
    • (1989) Nature , vol.340 , pp. 68-70
    • Herrera, R.E.1    Shaw, P.E.2    Nordheim, A.3
  • 31
    • 0026695645 scopus 로고
    • TCF by MAP kinase stimulates ternary complex formation at c-fos promoter
    • TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature 358, 414-417
    • (1992) Nature , vol.358 , pp. 414-417
    • Gille, H.1    Sharrocks, A.D.2    Shaw, P.E.3
  • 32
    • 0027980492 scopus 로고
    • Transient activation of Raf-1, MEK, ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo
    • Hipskind, R.A., Baccarini, M., and Nordheim, A. (1994) Transient activation of Raf-1, MEK, ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo. Mol. Cell. Biol. 14, 6219-6231
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6219-6231
    • Hipskind, R.A.1    Baccarini, M.2    Nordheim, A.3
  • 33
    • 0028084337 scopus 로고
    • Ternary complex factors: Growth factor regulated transcriptional activators
    • Treisman, R. (1994) Ternary complex factors: growth factor regulated transcriptional activators. Curr. Opin. Genet. Dev. 4, 96-101
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 96-101
    • Treisman, R.1
  • 34
    • 0028897113 scopus 로고
    • Transcriptional regulation by extracellular signals: Mechanisms and specificity
    • Hill, C. and Treisman, R. (1995) Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80, 199-211
    • (1995) Cell , vol.80 , pp. 199-211
    • Hill, C.1    Treisman, R.2
  • 35
    • 0023791129 scopus 로고
    • 5′ flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene
    • Tsai-Morris, C.-H., Cao, X., and Sukhatme, V.P. (1988) 5′ flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene. Nucleic Acids Res. 16, 8835-8846
    • (1988) Nucleic Acids Res. , vol.16 , pp. 8835-8846
    • Tsai-Morris, C.-H.1    Cao, X.2    Sukhatme, V.P.3
  • 36
    • 0024529079 scopus 로고
    • Structure of the NGFI-A gene and detection of upstream sequences responsible for its transcriptional induction by nerve growth factor
    • Changelian, P.S., Feng, P., King, T.C., and Milbrandt, J. (1989) Structure of the NGFI-A gene and detection of upstream sequences responsible for its transcriptional induction by nerve growth factor. Proc. Natl. Acad. Sci. USA 86, 377-381
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 377-381
    • Changelian, P.S.1    Feng, P.2    King, T.C.3    Milbrandt, J.4
  • 37
    • 0025904670 scopus 로고
    • 5′ upstream sequence and genomic structure of the human primary response gene, EGR-1/ TIS8
    • Sakamoto, K.M., Bardeleben, C., Yates, K.E., Raines, M.A., Golde, D.W., and Gasson, J.. (1991) 5′ upstream sequence and genomic structure of the human primary response gene, EGR-1/ TIS8. Oncogene 6, 867-871
    • (1991) Oncogene , vol.6 , pp. 867-871
    • Sakamoto, K.M.1    Bardeleben, C.2    Yates, K.E.3    Raines, M.A.4    Golde, D.W.5    Gasson, J.6
  • 38
    • 0032518291 scopus 로고    scopus 로고
    • Nerve growth factor promotes activation of the alpha, beta, and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells
    • Andjelkovic, M., Suidan, H.S., Meier, R., Frech, M., Alessi, D.R., and Hemmings, B.A. (1998) Nerve growth factor promotes activation of the alpha, beta, and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells. Eur. J. Biochem. 251, 195-200
    • (1998) Eur. J. Biochem. , vol.251 , pp. 195-200
    • Andjelkovic, M.1    Suidan, H.S.2    Meier, R.3    Frech, M.4    Alessi, D.R.5    Hemmings, B.A.6
  • 39
    • 0030042812 scopus 로고    scopus 로고
    • Nerve growth factor-stimulated nuclear S6 kinase in PC12 cells
    • Tang, T., Hirata, Y., Whalin, M., and Guroff, G. (1996) Nerve growth factor-stimulated nuclear S6 kinase in PC12 cells. J. Neurochem. 66, 1198-1206
    • (1996) J. Neurochem. , vol.66 , pp. 1198-1206
    • Tang, T.1    Hirata, Y.2    Whalin, M.3    Guroff, G.4
  • 40
    • 0028199799 scopus 로고
    • Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses
    • Stephens, R.M., Loeb, D.M., Copeland, T.D., Pawson, T., Greene, L.A., and Kaplan, D.R. (1994) Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses. Neuron 12, 691-705
    • (1994) Neuron , vol.12 , pp. 691-705
    • Stephens, R.M.1    Loeb, D.M.2    Copeland, T.D.3    Pawson, T.4    Greene, L.A.5    Kaplan, D.R.6
  • 41
    • 0028403448 scopus 로고
    • Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-zeta isoform
    • Coleman, E.S. and Wooten, M.W. (1994) Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-zeta isoform. J. Mol. Neurosci. 5, 39-57
    • (1994) J. Mol. Neurosci. , vol.5 , pp. 39-57
    • Coleman, E.S.1    Wooten, M.W.2
  • 42
    • 0029031232 scopus 로고
    • Selective translocation of potein kinase C-delta in PC12 cells during nerve growth factor-induced neuritogenesis
    • O'Driscoll, K.R., Teng, K.K., Fabbro, D., Greene, L.A., and Weinstein, I.B. (1995) Selective translocation of potein kinase C-delta in PC12 cells during nerve growth factor-induced neuritogenesis. Mol. Biol. Cell 6, 449-458
    • (1995) Mol. Biol. Cell , vol.6 , pp. 449-458
    • O'Driscoll, K.R.1    Teng, K.K.2    Fabbro, D.3    Greene, L.A.4    Weinstein, I.B.5
  • 43
    • 0030723178 scopus 로고    scopus 로고
    • Nucleolin is a protein kinase C-zeta substrate. Connection between cell surface signaling and nucleus in PC12 cells
    • Zhou, G., Seibenhener, M.L., and Wooten, M.W. (1997) Nucleolin is a protein kinase C-zeta substrate. Connection between cell surface signaling and nucleus in PC12 cells. J. Biol. Chem. 272, 31130-31137
    • (1997) J. Biol. Chem. , vol.272 , pp. 31130-31137
    • Zhou, G.1    Seibenhener, M.L.2    Wooten, M.W.3
  • 44
    • 0026666371 scopus 로고
    • Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells
    • Raffioni, S. and Bradshaw, R.A. (1992) Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells. Proc. Natl. Acad. Sci. USA 89, 9121-9125
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9121-9125
    • Raffioni, S.1    Bradshaw, R.A.2
  • 45
    • 0026756425 scopus 로고
    • Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains
    • Ohmichi, M., Decker, S.J., and Saltiel, A.R. (1992) Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains. Neuron 9, 769-777
    • (1992) Neuron , vol.9 , pp. 769-777
    • Ohmichi, M.1    Decker, S.J.2    Saltiel, A.R.3
  • 46
    • 0030812590 scopus 로고    scopus 로고
    • Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor
    • Holgado-Madruga, M., Moscatello, D.K., Emlet, D.R., Dieterich, R., and Wong, A.J. (1997) Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor. Proc. Natl. Acad. Sci. USA 94, 12419-12424
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12419-12424
    • Holgado-Madruga, M.1    Moscatello, D.K.2    Emlet, D.R.3    Dieterich, R.4    Wong, A.J.5
  • 48
    • 0029671217 scopus 로고    scopus 로고
    • GTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases
    • Heasley, L.E., Storey, B., Fanger, G.R., Butterfield, L., Zamarripa, J., Blumberg, D. and Maue, R.A. (1996) GTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases. Mol. Cell. Biol. 16, 648-656
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 648-656
    • Heasley, L.E.1    Storey, B.2    Fanger, G.R.3    Butterfield, L.4    Zamarripa, J.5    Blumberg, D.6    Maue, R.A.7
  • 49
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T., and Saltiel, A.R. (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 51
    • 0025075302 scopus 로고
    • Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells
    • Szeberenyi, J., Cai, H., and Cooper, G.M. (1990) Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells. Mol. Cell. Biol. 10, 5324-5332
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5324-5332
    • Szeberenyi, J.1    Cai, H.2    Cooper, G.M.3
  • 52
    • 0026534571 scopus 로고
    • Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases
    • Thomas, S.M., DeMarco, M., D'Arcangelo, G., Halegoua, S., and Brugge, J.S. (1992) Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68, 1031-1040
    • (1992) Cell , vol.68 , pp. 1031-1040
    • Thomas, S.M.1    DeMarco, M.2    D'Arcangelo, G.3    Halegoua, S.4    Brugge, J.S.5
  • 53
    • 0026523559 scopus 로고
    • Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
    • Wood, K.W., Sarnecki, C., Roberts, T.M., and Blenis, J. (1992) ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68, 1041-1050
    • (1992) Cell , vol.68 , pp. 1041-1050
    • Wood, K.W.1    Sarnecki, C.2    Roberts, T.M.3    Blenis, J.4
  • 54
    • 0024991898 scopus 로고
    • pEF-BOS, a powerful mammalian expression vector
    • Mizushima, S. and Nagata, S. (1990) pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18, 5322
    • (1990) Nucleic Acids Res. , vol.18 , pp. 5322
    • Mizushima, S.1    Nagata, S.2
  • 56
    • 0027716596 scopus 로고
    • Inhibition by cAMP of Ras-dependent activation of raf
    • Cook, S.J. and McCormick, F. (1993) Inhibition by cAMP of Ras-dependent activation of Raf. Science 262, 1069-1072
    • (1993) Science , vol.262 , pp. 1069-1072
    • Cook, S.J.1    McCormick, F.2
  • 58
    • 0023127059 scopus 로고
    • A rapid, sensitive, and inexpensive assay for chloramphenicol acetyltransferase
    • Nordeen, S.K., Green, P.P., and Fowlkes, D.M. (1987) A rapid, sensitive, and inexpensive assay for chloramphenicol acetyltransferase. DNA 6, 173-178
    • (1987) DNA , vol.6 , pp. 173-178
    • Nordeen, S.K.1    Green, P.P.2    Fowlkes, D.M.3
  • 59
    • 0027432424 scopus 로고
    • Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of 3,4,5-triphosphate in neutrophil responses
    • Arcaro, A. and Wymann, M.P. (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of 3,4,5-triphosphate in neutrophil responses. Biochem. J. 296, 297-301
    • (1993) Biochem. J. , vol.296 , pp. 297-301
    • Arcaro, A.1    Wymann, M.P.2
  • 60
    • 0028321727 scopus 로고
    • Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes
    • Thelen, M., Wymann, M.P., and Langen, H. (1994) Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc. Natl. Acad. Sci. USA 91, 4960-4964
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4960-4964
    • Thelen, M.1    Wymann, M.P.2    Langen, H.3
  • 61
    • 0029118603 scopus 로고
    • Wortmannin as a unique probe for an intracellular signalling protein phosphoinositide 3-kinase
    • Ui, M., Okada, T., Hazeki, K., and Hazeki, O. (1995) Wortmannin as a unique probe for an intracellular signalling protein phosphoinositide 3-kinase. Trends Biol. Sci. 20, 303-307
    • (1995) Trends Biol. Sci. , vol.20 , pp. 303-307
    • Ui, M.1    Okada, T.2    Hazeki, K.3    Hazeki, O.4
  • 63
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos, C.J., Matter, W.F., Hui, K.Y., and Brown, R.F. (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 269, 5241-5248
    • (1994) J. Biol. Chem. , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 65
    • 0030840413 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal signaling pathway
    • Logan, S.K., Falasca, M., Hu, P., and Schlessinger, J. (1997) Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal signaling pathway. Mol. Cell. Biol. 17, 5784-5790
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5784-5790
    • Logan, S.K.1    Falasca, M.2    Hu, P.3    Schlessinger, J.4
  • 66
    • 0029666270 scopus 로고    scopus 로고
    • Aggregation of the FcepsilonRI on mast cells stimulates c-Jun ammo-terminal kinase activity. A response inhibited by wortmannin
    • Ishizuka, T., Oshiba, A., Sakata, N., Terada, N., Johnson, G.L., and Gelfand, E.W. (1996) Aggregation of the FcepsilonRI on mast cells stimulates c-Jun ammo-terminal kinase activity. A response inhibited by wortmannin. J. Biol. Chem. 271, 12762-12766
    • (1996) J. Biol. Chem. , vol.271 , pp. 12762-12766
    • Ishizuka, T.1    Oshiba, A.2    Sakata, N.3    Terada, N.4    Johnson, G.L.5    Gelfand, E.W.6
  • 67
    • 0031956449 scopus 로고    scopus 로고
    • Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway
    • Kita, Y., Kimura, K.D., Kobayashi, M., Ihara, S., Kaibuchi, K., Kuroda, S., Ui, M., Iba, H., Konishi, H., Kikkawa, U., Nagata, S., and Fukui, Y. (1998) Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway. J. Cell Sci. 111, 907-915
    • (1998) J. Cell Sci. , vol.111 , pp. 907-915
    • Kita, Y.1    Kimura, K.D.2    Kobayashi, M.3    Ihara, S.4    Kaibuchi, K.5    Kuroda, S.6    Ui, M.7    Iba, H.8    Konishi, H.9    Kikkawa, U.10    Nagata, S.11    Fukui, Y.12
  • 68
    • 0028793798 scopus 로고
    • Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation
    • Cavigelli, M., Dolfi, F., Claret, F.-X., and Karin, M. (1995) Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation. EMBO J. 14, 5957-5964
    • (1995) EMBO J. , vol.14 , pp. 5957-5964
    • Cavigelli, M.1    Dolfi, F.2    Claret, F.-X.3    Karin, M.4
  • 69
    • 0029125757 scopus 로고
    • Integration of MAP kinase signal transduction pathways at the serum response element
    • Whitmarsh, A.J., Shore, P., Sharrocks, A.D., and Davis, R.J. (1995) Integration of MAP kinase signal transduction pathways at the serum response element. Science 269, 403-407
    • (1995) Science , vol.269 , pp. 403-407
    • Whitmarsh, A.J.1    Shore, P.2    Sharrocks, A.D.3    Davis, R.J.4
  • 70
    • 0031052087 scopus 로고    scopus 로고
    • Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase
    • Janknecht, R. and Hunter, T. (1997) Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase. J. Biol. Chem. 272, 4219-4224
    • (1997) J. Biol. Chem. , vol.272 , pp. 4219-4224
    • Janknecht, R.1    Hunter, T.2
  • 71
    • 0032508714 scopus 로고    scopus 로고
    • A mammalian scaffold complex that selectively mediates MAP kinase activation
    • Whitmarsh, A.J., Cavanagh, J., Tournier, C., Yasuda, J., and David, R.J. (1998) A mammalian scaffold complex that selectively mediates MAP kinase activation. Science 281, 1671-1674
    • (1998) Science , vol.281 , pp. 1671-1674
    • Whitmarsh, A.J.1    Cavanagh, J.2    Tournier, C.3    Yasuda, J.4    David, R.J.5
  • 72
    • 0027285638 scopus 로고
    • A branched signaling pathway for nerve growth factor is revealed by Src-Ras-, and Raf-mediated gene inductions
    • D'Arcangelo, G. and Halegoua, S. (1993) A branched signaling pathway for nerve growth factor is revealed by Src-Ras-, and Raf-mediated gene inductions. Mol. Cell. Biol. 13, 3146-3155
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3146-3155
    • D'Arcangelo, G.1    Halegoua, S.2
  • 73
    • 0032493812 scopus 로고    scopus 로고
    • Increasing complexity of the Ras signaling pathway
    • Vojtek, A.B. and Der, C.J. (1998) Increasing complexity of the Ras signaling pathway. J. Biol. Chem. 273, 19925-19928
    • (1998) J. Biol. Chem. , vol.273 , pp. 19925-19928
    • Vojtek, A.B.1    Der, C.J.2
  • 75
  • 76
    • 0031039024 scopus 로고    scopus 로고
    • Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
    • Franke, T.F., Kaplan, D.R., Cantley, L.C., and Toker, A. (1997) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science 275, 665-668
    • (1997) Science , vol.275 , pp. 665-668
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3    Toker, A.4
  • 77
    • 0031015986 scopus 로고    scopus 로고
    • A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain
    • Klippel, A., Kavanaugh, W.M., Pot, D., and Williams, L.T. (1997) A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. Mol. Cell. Biol. 17, 338-344
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 338-344
    • Klippel, A.1    Kavanaugh, W.M.2    Pot, D.3    Williams, L.T.4
  • 78
    • 0032511090 scopus 로고    scopus 로고
    • Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidyl-inositol 3-kinase
    • Wagle, A., Jivraj, S., Garlock, G.L., and Stapleton, S.R. (1998) Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidyl-inositol 3-kinase. J. Biol. Chem. 273, 14968-14974
    • (1998) J. Biol. Chem. , vol.273 , pp. 14968-14974
    • Wagle, A.1    Jivraj, S.2    Garlock, G.L.3    Stapleton, S.R.4
  • 79
    • 0030810216 scopus 로고    scopus 로고
    • Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport
    • Standaert, M.L., Galloway, L., Kamam, P., Bandyopadhyay, G., Moscat, J., and Farese, R.V. (1997) Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport. J. Biol. Chem. 272, 30075-30082
    • (1997) J. Biol. Chem. , vol.272 , pp. 30075-30082
    • Standaert, M.L.1    Galloway, L.2    Kamam, P.3    Bandyopadhyay, G.4    Moscat, J.5    Farese, R.V.6
  • 83
    • 0031854013 scopus 로고    scopus 로고
    • Downstream of phosphatidylinositol 3-kinase, a multifunctional signaling molecule, and its regulation in cell responses
    • Fukui, Y., Ihara, S., and Nagata, S. (1998) Downstream of phosphatidylinositol 3-kinase, a multifunctional signaling molecule, and its regulation in cell responses. J. Biochem. 124, 1-7
    • (1998) J. Biochem. , vol.124 , pp. 1-7
    • Fukui, Y.1    Ihara, S.2    Nagata, S.3
  • 84
    • 0027236369 scopus 로고
    • Phosphatidyl-inositol 3-kinase functions upstream of Ras and Raf in mediating insulin stimulation of c-fos transcription
    • Yamauchi, K., Holt, K., and Pessin, J.E. (1993) Phosphatidyl-inositol 3-kinase functions upstream of Ras and Raf in mediating insulin stimulation of c-fos transcription. J. Biol. Chem. 268, 14597-14600
    • (1993) J. Biol. Chem. , vol.268 , pp. 14597-14600
    • Yamauchi, K.1    Holt, K.2    Pessin, J.E.3
  • 85
    • 0028882512 scopus 로고
    • Involvement of phosphatidylinositol 3-kinase in the activation of extracellular signal-regulated kinase by PDGF in hepatic stellate cells
    • Marra, F., Pinzani, M., DeFranco, R., Laffi, G., and Gentilli, P. (1995) Involvement of phosphatidylinositol 3-kinase in the activation of extracellular signal-regulated kinase by PDGF in hepatic stellate cells. FEBS Lett. 376, 141-145
    • (1995) FEBS Lett. , vol.376 , pp. 141-145
    • Marra, F.1    Pinzani, M.2    DeFranco, R.3    Laffi, G.4    Gentilli, P.5
  • 86
    • 0028850452 scopus 로고
    • Wortmannin and its analogue demethoxyvirridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells
    • Cross, M.J., Stewart, A., Hodgkin, M.N., Kerr, D.J., and Wakelam, M.J.O. (1995) Wortmannin and its analogue demethoxyvirridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. J. Biol. Chem. 270, 25352-25355
    • (1995) J. Biol. Chem. , vol.270 , pp. 25352-25355
    • Cross, M.J.1    Stewart, A.2    Hodgkin, M.N.3    Kerr, D.J.4    Wakelam, M.J.O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.