Differential effects of NMDA and AMPA/kainate receptor antagonists on superoxide production and MnSOD activity in rat brain following intrahippocampal injection

Brain Research Bulletin

Volumn 64, Issue 1, 2004, Pages 85-93

  Radenovic, L ^a   Selakovic, V ^b   Kartelija, G ^a   Todorovic, N ^a   Nedeljkovic, M ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b UNIVERSITY OF DEFENCE   (Serbia)

Author keywords

APV; CNQX; Excitotoxicity; Kainate; Neuroprotection; Oxidative stress

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; GLUTAMATE RECEPTOR ANTAGONIST; KAINIC ACID; KAINIC ACID RECEPTOR; KAINIC ACID RECEPTOR ANTAGONIST; MANGANESE SUPEROXIDE DISMUTASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CELL; BRAIN CORTEX; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DRUG SELECTIVITY; DYNAMICS; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; FOREBRAIN; HIPPOCAMPUS; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 3242683331     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2004.06.001     Document Type: Article

References (46)

1. Akai F., Maeda M., Suzuki K., Inagaki S., Takagi H., Taniguchi N. Immunocytochemical localization of MnSOD in the hippocampus of the rat. Neurosci. Lett. 115:1990;19-23
2. Alabadi J., Thibault J.L., Pinard E., Seylaz J., Lasbennes F. 7-Nitroindazole a selective inhibitor of nNOS increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats. Brain Res. 839:1999;305-312
3. Bailey A., Kelland E.E., Thomas A., Biggs J., Creawford D., Kitchen I., Toms N.J. Regional mapping of low affinity kainate receptors in mouse brain using [3H] (2S, 4R)-4-methylglutamate autoradiography. Eur. J. Pharmacol. 431:2001;305-310
4. Bidmon H.J., Kato K., Schleicher A., Witte O.W., Zilles K. Transient increase of Mn-superoxide dismutase in remote brain areas after focal photothrombotic cortical lesion. Stroke. 29:1997;203-211
5. Budd S.L., Castilho R.F., Nicholls D.G. Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cultured cerebellar granule cells. FEBS Lett. 415:1997;21-24
6. Budd S.L., Nicholls D. Mitochondrial, calcium regulation acute glutamate excitotoxicity in cultured cerebral granule cells. J. Neurochem. 76:1996;2282-2291
7. 2+ overload and ROS generation in spinal motor neurons in vitro. J. Neurosci. 20:2000;240-250
8. 2+ rises and consequent oxygen radical production. J. Neurosci. 18:1998;7727-7738
9. Carriedo S.G., Yin H.Z., Weiss J.H. Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro. J. Neurosci. 16:1996;4069-4079
10. Cassarino D.S., Bennett J.P. An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. Brain Res. Rev. 29:1999;1-25
11. Ciriolo M.R., De Martino A., Lafavia E., Rossi L., Carri M.T., Rotilio G. Cu, Zn-superoxide dismutase dependent apoptosis induced by nitric oxide in neuronal cells. J. Biol. Chem. 275:2000;5065-5072
12. Coyle J.T., Puttfarcken P. The effects of oxidative stress on the brain. Science. 262:1993;689-695
13. Dugan L.L., Sensi S.L., Canzoniero L.M.T., Handran S.D., Rothman S.M., Lin T.S., Goldberg M.P., Choi D.W. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. J. Neurosci. 15:1995;6377-6388
14. Fridovich I. Superoxide radical and superoxide dismutases. Annu. Rev. Biochem. 64:1995;97-112
15. Gonzalez-Zulueta M., Ensz L.M., Mukhina G., Lebovitz R.M., Zwacka R.M., Engelhardt J.F., Oberlay L.W., Dawson V.L., Dawson T.M. Mn-superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity. J. Neurosci. 18:1999;2040-2055
16. Halasz A.S., Palfi M., Tabi T., Magyar K., Szoko E. Altered nitric oxide production in mouse brain after administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydro-pyridin or methamphetamine. Neurochem. Int. 44:2004;641-646
17. Heales S.J.R., Bolanos J.P., Stewart V.C., Brookes P.S., Land J.M., Clark J.B. Nitric oxide, mitochondria and neurological disease. Biochim. Biophys. Acta. 1410:1999;215-228
18. 2+ concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators. J. Neurosci. 17:1997;6669-6677
19. Hussain S.P., Amstad P., He P., Robles A., Lupold S., Kaneko I., Ichimiya M., Sengupta S., Mechanic L., Okamura S., Hofseth L.J., Moake M., Nagashima M., Forrester K.S., Harris C.C. p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis. Cancer Res. 64:2004;2350-2356
20. Janssens N., Lesage A.S.J. Glutamate receptor subunit expression in primary neuronal and secondary glial cultures. J. Neurochem. 77:2001;1457-1474
21. Keller J.N., Kindy M.S., Holtsberg F.W., Clair D.K.St., Yen H.C., Germeyer A., Steiner S.M., Bruce-Keller A.J., Hutchins J.B., Mattson M.P. Mitochondrial MnSOD prevents neuronal apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation and mitochondrial dysfunction. J. Neurosci. 18:1998;687-697
22. Kim H.C., Jhoo W.K., Kim W.K., Suh J.H., Shin E.J., Kato K., Ho Ko K. An immunocytochemical study of mitochondrial MnSOD in the rat hippocampus after kainate administration. Neurosci. Lett. 281:2000;65-68
23. Koh J., Goldberg M.P., Hartley D.M., Choi D.W. Non-NMDA-receptor-mediated neurotoxicity in cortical culture. J. Neurosci. 10:1990;693-705
24. Lee M.H., Hyun D.H., Halliwell B., Jenner P. Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutase on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases and protection by Bcl-2. J. Neurochem. 78:2001;209-220
25. Li Q.Y., Pedersen C., Day B.J., Patel M. Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation. J. Neurochem. 78:2001;746-755
26. Li Y., Copin J.C., Reola L.F., Calagui B., Gobbel G.T., Chen S.F., Sato S., Epstein C.J., Chan P.H. Reduced mitochondrial Mn-superoxide dismutase activity exacerbates glutamate toxicity in cultured mouse cortical neurons. Brain Res. 814:1998;164-170
27. Liang L.P., Ho Y.S., Patel M. Mitochondrial superoxide production in kainate-induced hippocampal damage. Neuroscience. 101:2000;563-570
28. Lindenau J., Noack H., Possel H., Asayama K., Wolf G. Cellular distribution of superoxide dismutases in the rat CNS. Glia. 29:2000;25-34
29. Lowry O., Rosenbrough N.J., Fall A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275
30. 2+ influx underlies potent induction of injury. J. Neurosci. 16:1996;5457-5465
31. Nakaki T., Mishima A., Suzuki E., Shintani F., Fujii T. Glufosinate ammonium stimulates nitric oxide production through N-methyl D-aspartate receptors in rat cerebellum. Neurosci. Lett. 290:2000;209-212
32. Nicholls D.G., Budd S.L. Mitochondria and neuronal glutamate excitotoxicity. Biochim. Biophys. Acta. 1366:1999;97-112
33. Nicholls D.G., Budd S.L. Mitochondria and neuronal survival. Physiol. Rev. 80:2000;315-360
34. Patel M., Li Q.Y. Age dependence of seizure-induced oxidative stress. Neuroscience. 118:2003;431-437
35. 2+ accumulation in striatal neurons. Exp. Neurol. 149:1998;1-12
36. Pinteaux E., Copin J.C., Ledig M., Tholey G. Modulation of oxygen-radical-scavenging enzymes by oxidative stress in primary cultures of rat astroglial cells. Dev. Neurosi. 18:1996;397-404
37. Radenovic L., Vasiljevic I., Selakovic V., Jovanovic M. 7-Nitroindazole reduces nitrite concentration in rat brain after intrahippocampal kainate-induced seizure. Com. Biochem. Physiol. C Tox. Phar. 135:2003;443-450
38. Sengpiel B., Preis E., Krieglstein J., Prehn J.H.M. NMDA-induced superoxide production and neurotoxicity in cultured rat hippocampal neurons: role if mitochondria. Eur. J. Neurosci. 10:1998;1903-1910
39. Skaper S.D., Facci L., Kee W.J., Strijbos P.J.L.M. Potentiation by histamine of synaptically mediated excitotoxicity in cultured hippocampal neurons: a possible role for mast cells. J. Neurosci. 76:2001;47-55
40. Spitz D.R., Oberley D.R. Assay of superoxide dismutase activity in the tumor tissue. Meth. Enzymol. 105:1989;457-464
41. Trotti D., Rizzini B.L., Rossi D., Haugeto O., Racagni G., Danbolt N.C., Volterra A. Neuronal and glial glutamate transporters posses an SH-based redox regulatory mechanics. Eur. J. Neurosci. 9:1997;1236-1243
42. Trotti D., Rossi D., Gjesdal O., Levy L.M., Racagni G., Danbolt N.C., Volterra A. Peroxynitrite inhibits glutamate transporter subtypes. Biol. Chem. 271:1996;5976-5979
43. Tseng W.P., Lin-Shiau S.Y. Activation of NMDA receptor partly involved in beta-bungarotoxin-induced neurotoxicity in cultured primary neurons. Neurochem. Int. 42:2003;333-344
44. Urenjak J., Obrenovitch T.P. Kynurenine 3-hydroxylase inhibition in rats: effects on extracellular kynurenic acid concentration and N-methyl-D-aspartate- induced depolarisation in the striatum. J. Neurochem. 75:2000;2427-2433
45. Varju P., Schlett K., Eisel U., Madarasz E. Schedule of NMDA receptor subunit expression and functional channel formation in the course of in vitro-induced neurogenesis. J. Neurochem. 77:2001;1444-1456
46. Weiss J.H., Yin H.Z., Choi D.W. Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity. Neuroscience. 60:1994;659-664