Proteomics in cancer cell research: An analysis of therapy resistance

Pathology Research and Practice

Volumn 200, Issue 2, 2004, Pages 105-117

  Lage, Hermann ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

2D PAGE; Cancer; Drug resistance; Thermoresistance

Indexed keywords

ABC TRANSPORTER; CARRIER PROTEIN; CELL PROTEIN; CISPLATIN; COLCHICINE; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; FOTEMUSTINE; GLYCOPROTEIN P; HEAT SHOCK PROTEIN 27; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MELPHALAN; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; PROTEIN 14 3 3; VINBLASTINE; VINCRISTINE; VINDESINE;

ANTIGEN PRESENTATION; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CANCER RESEARCH; CELL STRAIN KB; COLON CARCINOMA; CONTROLLED STUDY; FIBROSARCOMA; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEAT TOLERANCE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; LUNG CANCER; MALIGNANT NEOPLASTIC DISEASE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MELANOMA; MULTIDRUG RESISTANCE; PANCREAS CARCINOMA; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MICROARRAY; PROTEOMICS; STOMACH CARCINOMA; TWO DIMENSIONAL GEL ELECTROPHORESIS; TWO HYBRID SYSTEM; UTERINE CERVIX CARCINOMA;

EID: 3242668211     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prp.2004.02.003     Document Type: Article

References (89)

1. Adam P.J. Boyd R. Tyson K.L. Fletcher G.C. Stamps A. Hudson L. Poyser H.R. Redpath N. Griffiths M. Steers G. Harris A.L. Patel S. Berry J. Loader J.A. Townsend R.R. Daviet L. Legrain P. Parekh R. Terrett J.A. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer J. Biol. Chem. 278 2003 6482-6489
2. Adriaenssens E. Lemoine J. El Yazidi-Belkoura I. Hondermarck H. Growth signaling in breast cancer cells: outcomes and promises of proteomics Biochem. Pharmacol. 64 2002 797-803
3. Ambudkar S.V. Kimchi-Sarfaty C. Sauna Z.E. Gottesman M.M. P-glycoprotein: from genomics to mechanism Oncogene 22 2003 7468-7485
4. Anderson L. Seilhamer J. Acomparison of selected mRNA and protein abundances in human liver Electrophoresis 18 1997 533-537
5. Banks R.E. Dunn M.J. Hochstrasser D.F. Sanchez J.C. Blackstock W. Pappin D.J. Selby P.J. Proteomics: new perspectives, new biomedical opportunities Lancet 356 2000 1749-1756
6. Camp R.L. Chung G.G. Rimm D.L. Automated subcellular localization and quantification of protein expression in tissue microarrays Nat. Med. 8 2002 1323-1327
7. Chan T.A. Hermeking H. Lengauer C. Kinzler K.W. Vogelstein B. 14-3-3σ is required to prevent mitotic catastrophe after DNA damage Nature 401 1999 616-620
8. Chen S.T. Pan T.L. Tsai Y.C. Huang C.M. Proteomics reveals protein profile changes in doxorubicin-treated MCF-7 human breast cancer cells Cancer Lett. 181 2002 95-107
9. Dietel M. Arps H. Lage H. Niendorf A. Membrane vesicle formation due to acquired mitoxantrone resistance in human gastric carcinoma cell line EPG85-257 Cancer Res. 50 1990 6100-6106
10. Dunn I.S. Phage display of proteins Curr. Opin. Biotechnol. 7 1996 547-553
11. Ehrnsperger M. Graber S. Gaestel M. Buchner J. Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation EMBO J. 16 1997 221-229
12. Falk M.H. Issels R.D. Hyperthermia in oncology Int. J. Hyperthermia 17 2001 1-18
13. Fey S.J. Larsen P.M. 2D or not 2D. Two-dimensional gel electrophoresis Curr. Opin. Chem. Biol. 5 2001 26-33
14. Fields S. Song O. A novel genetic system to detect protein-protein interactions Nature 340 1989 245-246
15. Fortin A. Raybaud-Diogene H. Tetu B. Deschenes R. Huot J. Landry J. Overexpression of the 27 kDa heat shock protein is associated with thermoresistance and chemoresistance but not with radioresistance Int. J. Radiat. Oncol. Biol. Phys. 46 2000 1259-1266
16. Fountoulakis M. Hardmeier R. Hoger H. Lubec G. Postmortem changes in the level of brain proteins Exp. Neurol. 167 2001 86-94
17. Fu H. Subramanian R.R. Masters S.C. 14-3-3 proteins: structure, function, and regulation Annu. Rev. Pharmacol. Toxicol. 40 2000 617-647
18. Gorg A. Obermaier C. Boguth G. Harder A. Scheibe B. Wildgruber R. Weiss W. The current state of two-dimensional electrophoresis with immobilized pH gradients Electrophoresis 21 2000 1037-1053
19. Han E.K. Tahir S.K. Cherian S.P. Collins N. Ng S.C. Modulation of paclitaxel resistance by annexin IV in human cancer cell lines Br. J. Cancer 83 2000 83-88
20. Hanash S.M. Biomedical applications of two-dimensional electrophoresis using immobilized pH gradients: current status Electrophoresis 21 2000 1202-1209
21. Hanash S. Disease proteomics Nature 422 2003 226-232
22. Hathout Y. Riordan K. Gehrmann M. Fenselau C. Differential protein expression in the cytosol fraction of an MCF-7 breast cancer cell line selected for resistance toward melphalan J. Proteome. Res. 1 2002 435-442
23. Hermeking H. Lengauer C. Polyak K. He T.C. Zhang L. Thiagalingam S. Kinzler K.W. Vogelstein B. 14-3-3σ is a p53-regulated inhibitor of G2/M progression Mol. Cell 1 1997 3-11
24. Hoang V.M. Foulk R. Clauser K. Burlingame A. Gibson B.W. Fisher S.J. Functional proteomics: examining the effects of hypoxia on the cytotrophoblast protein repertoire Biochemistry 40 2001 4077-4086
25. Hondermarck H. Vercoutter-Edouart A.S. Revillion F. Lemoine J. el-Yazidi-Belkoura I. Nurcombe V. Peyrat J.P. Proteomics of breast cancer for marker discovery and signal pathway profiling Proteomics 1 2001 1216-1232
26. Hondermarck H. Dolle L. El Yazidi-Belkoura I. Vercoutter-Edouart A.S. Adriaenssens E. Lemoine J. Functional proteomics of breast cancer for signal pathway profiling and target discovery J. Mammary Gland Biol. Neoplasia 7 2002 395-405
27. Huang Y. Sadée W. Drug sensitivity and resistance genes in cancer chemotherapy: a chemogenomics approach Drug Discov. Today 8 2003 356-363
28. Humphery-Smith I. Cordwell S.J. Blackstock W.P. Proteome research: complementarity and limitations with respect to the RNA and DNA worlds Electrophoresis 18 1997 1217-1242
29. Hutchens T.W. Yip T.T. New desorption strategies for the mass analysis of macromolecules Rapid Commun. Mass Spectrom. 7 1993 576-580
30. Hütter G. Sinha P. Proteomics for studying cancer cells and the development of chemoresistance Proteomics 1 2001 1233-1248
31. Izquierdo M.A. Neefjes J.J. Mathari A.E. Flens M.J. Scheffer G.L. Scheper R.J. Overexpression of the ABC transporter TAP in multidrug-resistant human Br. J. Cancer 74 1996 1961-1967
32. Jolly C. Morimoto R.I. Role of the heat shock response and molecular chaperones in oncogenesis and cell death J. Natl. Cancer Inst. 92 2000 1564-1572
33. Kaltschmidt E. Wittmann H.G. Ribosomal proteins. VII. Two-dimensional polyacrylamide gel electrophoresis for fingerprinting of ribosomal proteins Anal. Biochem. 36 1970 401-412
34. Kaltschmidt E. Wittmann H.G. Ribosomal proteins. XII. Number of proteins in small and large ribosomal subunits of E. coli as determined by two-dimensional gel electrophoresis Proc. Natl. Acad. Sci. USA 67 1970 1276-1282
35. Kaufmann S.H. Vaux D.L. Alterations in the apoptotic machinery and their potential role in anticancer drug resistance Oncogene 22 2003 7414-7430
36. Kononen J. Bubendorf L. Kallioniemi A. Barlund M. Schraml P. Leighton S. Torhorst J. Mihatsch M.J. Sauter G. Kallioniemi O.P. Tissue microarrays for high-throughput molecular profiling of tumor specimens Nat. Med. 4 1998 844-847
37. Kruh G.D. Belinsky M.G. The MRP family of drug efflux pumps Oncogene 22 2003 7537-7552
38. Lage H. Dietel M. Effect of the breast-cancer resistance protein on atypical multidrug resistance Lancet Oncol. 1 2000 169-175
39. Lage H. Jordan A. Scholz R. Dietel M. Thermosensitivity of multidrug-resistant human gastric and pancreatic carcinoma cells Int. J. Hyperthermia 16 2000 291-303
40. Lage H. Perlitz C. Abele R. Tampé R. Dietel M. Schadendorf D. Sinha P. Enhanced expression of human ABC-transporter tap is associated with cellular resistance to mitoxantrone FEBS Lett. 503 2001 179-184
41. Lage H. Dietel M. Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells J. Cancer Res. Clin. Oncol. 128 2002 349-357
42. Lage H. ABC-transporters: implications on drug resistance from microorganisms to human cancers Int. J. Antimicrob. Agents 22 2003 188-199
43. Lander E.S. Linton L.M. Birren B. Nusbaum A. Zody C. et al. International human genome sequencing consortium, Initial sequencing and analysis of the human genome Nature 409 2001 860-921
44. Lavoie J.N. Gingras-Breton G. Tanguay R.M. Landry J. Induction of Chinese hamster HSP27 gene expression in mouse cells confers resistance to heat shock. HSP27 stabilization of the microfilament organization J. Biol. Chem. 268 1993 3420-3429
45. Lawrie L.C. Fothergill J.E. Murray G.I. Spot the differences: proteomics in cancer research Lancet Oncol. 2 2001 270-277
46. Mann M. Jensen O.N. Proteomic analysis of post-translational modifications Nat. Biotechnol. 21 2003 255-261
47. McLafferty F.W. Fridriksson E.K. Horn D.M. Lewis M.A. Zubarev R.A. Techview: biochemistry. Biomolecule mass spectrometry Science 284 1999 1289-1290
48. Melis R. White R. Characterization of colonic polyps by two-dimensional gel electrophoresis Electrophoresis 20 1999 1055-6104
49. Möller A. Malerczyk C. Völker U. Stöppler H. Maser E. Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis Proteomics 2 2002 697-705
50. Moriyama M. Hoshida Y. Otsuka M. Nishimura S. Kato N. Goto T. Taniguchi H. Shiratori Y. Seki N. Omata M. Relevance network between chemosensitivity and transcriptome in human hepatoma cells Mol. Cancer Ther. 2 2003 199-205
51. Neefjes J.J. Momburg F. Hammerling G.J. Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter Science 261 1993 769-771
52. O'Farrell P.H. High-resolution two-dimensional electrophoresis of proteins J. Biol. Chem. 250 1975 4007-4021
53. Ostergaard M. Rasmussen H.H. Nielsen H.V. Vorum H. Orntoft T.F. Wolf H. Celis J.E. Proteome profiling of bladder squamous cell carcinomas: identification of markers that define their degree of differentiation Cancer Res. 57 1997 4111-4117
54. Ozawa M. Muramatsu T. Reticulocalbin. A novel endoplasmic reticulum resident Ca(2+)-binding protein with multiple EF-hand motifs and a carboxyl-terminal HDEL sequence J. Biol. Chem. 268 1993 699-705
55. Pandey A. Mann M. Proteomics to study genes and genomes Nature 405 2000 837-846
56. Pantazis P. Preclinical studies of water-insoluble camptothecin congeners: cytotoxicity, development of resistance, and combination treatments Clin. Cancer Res. 1 1995 1235-1244
57. Poland J. Schadendorf D. Lage H. Schnölzer M. Celis J.E. Sinha P. Study of therapy resistance in cancer cells with functional proteome analysis Clin. Chem. Lab. Med. 40 2002 221-234
58. Poland J. Urbani A. Lage H. Schnölzer M. Sinha P. Study of the development of thermoresistance in human pancreatic carcinoma cell lines using proteome analysis Electrophoresis 25 2004 173-183
59. Rosty C. Christa L. Kuzdzal S. Baldwin W.M. Zahurak M.L. Carnot F. Chan D.W. Canto M. Lillemoe K.D. Cameron J.L. Yeo C.J. Hruban R.H. Goggins M. Identification of hepatocarcinoma-intestine-pancreas/ pancreatitis-associated protein I as a biomarker for pancreatic ductal adenocarcinoma by protein biochip technology Cancer Res. 62 2002 1868-1875
60. Schmid J.A. Sitte H.H. Fluorescence resonance energy transfer in the study of cancer pathways Curr. Opin. Oncol. 15 2003 55-64
61. Seow T.K. Ong S.E. Liang R.C. Ren E.C. Chan L. Ou K. Chung M.C. Two-dimensional electrophoresis map of the human hepatocellular carcinoma cell line, HCC-M, and identification of the separated proteins by mass spectrometry Electrophoresis 21 2000 1787-1813
62. Shen D.W. Akiyama S. Schoenlein P. Pastan I. Gottesman M.M. Characterisation of high-level cisplatin-resistant cell lines established from a human hepatoma cell line and human KB adenocarcinoma cells: cross-resistance and protein changes Br. J. Cancer 71 1995 676-683
63. Shen D.W. Cardarelli C. Hwang J. Cornwell M. Richert N. Ishii S. Pastan I. Gottesman M.M. Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins J. Biol. Chem. 261 1986 7762-7770
64. Shi Y. Han Y. Wang X. Zhao Y. Ning X. Xiao B. Fan D. MGr1-Ag is associated with multidrug-resistant phenotype of gastric cancer cells Gastric Cancer 5 2002 154-159
65. Shiwa M. Nishimura Y. Wakatabe R. Fukawa A. Arikuni H. Ota H. Kato Y. Yamori T. Rapid discovery and identification of a tissue-specific tumor biomarker from 39 human cancer cell lines using the SELDI ProteinChip platform Biochem. Biophys. Res. Commun. 309 2003 18-25
66. Sinha P. Hütter G. Köttgen E. Dietel M. Schadendorf D. Lage H. Increased expression of annexin I and thioredoxin detected by two-dimensional gel electrophoresis of drug resistant human stomach cancer cells J. Biochem. Biophys. Methods 18 1998 105-116
67. Sinha P. Hütter G. Köttgen E. Dietel M. Schadendorf D. Lage H. Increased expression of epidermal fatty acid binding protein, cofilin, and 14-3-3-σ (stratifin) detected by two-dimensional gel electrophoresis, mass spectrometry and micosequencing of drug-resistant human adenocarcinoma of the pancreas Electrophoresis 20 1999 2952-2960
68. Sinha P. Hütter G. Köttgen E. Dietel M. Schadendorf D. Lage H. Search for novel proteins involved in the development of chemoresistance in colorectal cancer and fibrosarcoma cells in vitro using two-dimensional electrophoresis, mass spectrometry and microsequencing Electrophoresis 20 1999 2961-2969
69. Sinha P. Kohl S. Fischer J. Hütter G. Kern M. Köttgen E. Dietel M. Lage H. Schnölzer M. Schadendorf D. Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis Electrophoresis 21 2000 3048-3057
70. Sinha P. Poland J. Schnölzer M. Celis J.E. Lage H. Characterization of the differential protein expression associated with thermoresistance in human gastric carcinoma cell lines Electrophoresis 22 2001 2990-3000
71. Sinha P. Poland J. Kohl S. Schnölzer M. Helmbach H. Hütter G. Lage H. Schadendorf D. Study of the development of chemoresistance in melanoma cell lines using proteome analysis Electrophoresis 24 2003 2386-2404
72. Sreekumar A. Nyati M.K. Varambally S. Barrette T.R. Ghosh D. Lawrence T.S. Chinnaiyan A.M. Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins Cancer Res. 61 2001 7585-7593
73. Sreekumar A. Chinnaiyan A.M. Using protein microarrays to study cancer, Biotechniques (Suppl.) (2002) 46-53.
74. Stein U. Lage H. Jordan A. Walther W. Bates S.E. Litman T. Hohenberger P. Dietel M. Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells Int. J. Cancer 97 2002 751-760
75. Steinberg T.H. Jones L.J. Haugland R.P. Singer V.L. SYPRO orange and SYPRO red protein gel stains: one-step fluorescent staining of denaturing gels for detection of nanogram levels of protein Anal. Biochem. 239 1996 223-237
76. Stierum R. Gaspari M. Dommels Y. Ouatas T. Pluk H. Jespersen S. Vogels J. Verhoeckx K. Groten J. van Ommen B. Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2 Biochim. Biophys. Acta 1650 2003 73-91
77. Takeuchi K. Nakamura K. Fujimoto M. Kaino S. Kondoh S. Okita K. Heat stress-induced loss of eukaryotic initiation factor 5A (eIF-5A) in a human pancreatic cancer cell line, MIA PaCa-2, analyzed by two-dimensional gel electrophoresis Electrophoresis 23 2002 662-669
78. Tomlinson A.J. Hincapie M. Morris G.E. Chicz R.M. Global proteome analysis of a human gastric carcinoma Electrophoresis 23 2002 3233-3240
79. Tönnies H. Poland J. Sinha P. Lage H. Association of genomic imbalances with drug resistance and thermoresistance in human gastric carcinoma cells Int. J. Cancer 103 2003 752-758
80. Venter J.C. Adams M.D. Myers E.W. Li P.W. Mural R.J. et al. The sequence of the human genome Science 291 2001 1304-1351
81. Vercoutter-Edouart A.S. Lemoine J. Le Bourhis X. Louis H. Boilly B. Nurcombe V. Revillion F. Peyrat J.P. Hondermarck H. Proteomic analysis reveals that 14-3-3σ is down-regulated in human breast cancer cells Cancer Res. 61 2001 76-80
82. Wang H. Kachman M.T. Schwartz D.R. Cho K.R. Lubman D.M. A protein molecular weight map of ES2 clear cell ovarian carcinoma cells using a two-dimensional liquid separations/mass mapping technique Electrophoresis 23 2002 3168-3181
83. Wasinger V.C. Cordwell S.J. Cerpa-Poljak A. Yan J.X. Gooley A.A. Wilkins M.R. Duncan M.W. Harris R. Williams K.L. Humphery-Smith I. Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium Electrophoresis 16 1995 1090-1094
84. Wilkins M.R. Sanchez J.C. Gooley A.A. Appel R.D. Humphery-Smith I. Hochstrasser D.F. Williams K.L. Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it Biotech. Gen. Eng. Rev. 13 1995 19-50
85. Wu W. Tang X. Hu W. Lotan R. Hong W.K. Mao L. Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry Clin. Exp. Metastasis 19 2002 319-326
86. Wust P. Hildebrandt B. Sreenivasa G. Rau B. Gellermann J. Riess H. Felix R. Schlag P.M. Hyperthermia in combined treatment of cancer Lancet Oncol. 3 2002 487-497
87. Yang H.Y. Wen Y.Y. Chen C.H. Lozano G. Lee M.H. 14-3-3 sigma positively regulates p53 and suppresses tumor growth Mol. Cell Biol. 23 2003 7096-7107
88. Yazidi-Belkoura I.E. Adriaenssens E. Vercoutter-Edouart A.S. Lemoine J. Nurcombe V. Hondermarck H. Technol. Cancer Res. Treat 1 2002 287-296
89. Yu L.R. Shao X.X. Jiang W.L. Xu D. Chang Y.C. Xu Y.H. Xia Q.C. Proteome alterations in human hepatoma cells transfected with antisense epidermal growth factor receptor sequence Electrophoresis 22 2001 3001-3008