Overexpression of the 27 KDa heat shock protein is associated with thermoresistance andchemoresistance but not with radioresistance

International Journal of Radiation Oncology Biology Physics

Volumn 46, Issue 5, 2000, Pages 1259-1266

  Fortin, André ^a   Raybaud Diogène, Hélène ^b   Têtu, Bernard ^a   Huot, Jacques ^a   Landry, Jacques ^a   Deschenes M sc, Réna ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b Laboratory of Oral Pathologie   (France)

Author keywords

Chemoresistance; GST; Heat shock protein; hsp27; Thermoresistance

Indexed keywords

CISPLATIN; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN 27; KI 67 ANTIGEN; PROTEIN P53;

ANIMAL CELL; ARTICLE; BIOPSY; CELL LINE; CHEMOSENSITIVITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; HEAD AND NECK CARCINOMA; HEAT SHOCK; HEAT TOLERANCE; HUMAN; HUMAN TISSUE; IMMUNOCHEMISTRY; IN VITRO STUDY; MAJOR CLINICAL STUDY; NONHUMAN; PLOIDY; PRIORITY JOURNAL; RADIOSENSITIVITY; SQUAMOUS CELL CARCINOMA;

ANIMALS; BIOLOGICAL MARKERS; CARCINOMA, SQUAMOUS CELL; CELL LINE; CELL SURVIVAL; CRICETINAE; CRICETULUS; DRUG RESISTANCE, NEOPLASM; FEMALE; GLUTATHIONE TRANSFERASE; HEAD AND NECK NEOPLASMS; HEAT-SHOCK PROTEINS; HUMANS; HYPERTHERMIA, INDUCED; MALE; MICE; NEOPLASM PROTEINS; RADIATION TOLERANCE; RADIOBIOLOGY; TRANSFECTION;

EID: 0034653824     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(99)00410-1     Document Type: Article

References (54)

1. Ensley J.F., Jacobs J.R., Weaver A., Kinzie J., Crissman J., Kish J.A., Cummings G., Al-Sarraf M. Correlation between response to cisplatinum-combination chemotherapy and subsequent radiotherapy in previously untreated patients with advanced squamous cell cancers of the head and neck. Cancer. 54:1984;811-814.
2. Lefebvre J.L., Chevalier D., Luboinski B., Kirkpatrick A., Collette L., Sahmoud T. Larynx preservation in pyriform sinus cancer preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative Group . J Natl Cancer Inst. 88:1996;890-899.
3. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med. 324:1991;1685-1690.
4. Ensley J.F., Ahmad K., Kish J. Improved response to radiation and concurrent cisplatinum in patients with advanced head and neck cancers that fail induction chemotherapy. J Clin Oncol. 8:1989;168.
5. Huot J., Roy G., Lambert H., Chretien P., Landry J. Increased survival after treatments with anticancer agents of Chinese hamster cells expressing the human Mr 27,000 heat shock protein. Cancer Res. 51:1991;5245-5252.
6. Raaphorst G.P., Mao J.P., Ng C.E. Thermotolerance effects on thermoradiosensitization in human glioma cells. Int J Hyperthermia. 14:1998;85-96.
7. Tetu B., Lacasse B., Bouchard H.L., Lagace R., Huot J., Landry J. Prognostic influence of HSP-27 expression in malignant fibrous histiocytoma A clinicopathological and immunohistochemical study . Cancer Res. 52:1992;2325-2328.
8. Ozols R.F., Masuda H., Hamilton T.C. Mechanisms of cross-resistance between radiation and antineoplastic drugs. NCI Monogr. 6:1988;165.
9. Landry J., Bernier D., Chretien P., Nicole L.M., Tanguay R.M., Marceau N. Synthesis and degradation of heat shock proteins during development and decay of thermotolerance. Cancer Res. 42:1982;2457-2461.
10. Sun J., Chen Y., Li M., Ge Z. Role of antioxidant enzymes on ionizing radiation resistance. Free Radic Biol Med. 24:1998;586-593.
11. Mehlen P., Kretz-Remy C., Preville X., Arrigo A.P. Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death. EMBO J. 15:1996;2695-2706.
12. Arrigo A.P. Small stress proteins Chaperones that act as regulators of intracellular redox state and programmed cell death . Biol Chem. 379:1998;19-26.
13. Raybaud-Diogene H., Fortin A., Morency R., Roy J., Monteil R.A., Tetu B. Markers of radioresistance in squamous cell carcinomas of the head and neck A clinicopathologic and immunohistochemical study . J Clin Oncol. 15:1997;1030-1038.
14. Hsu S.M., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques A comparison between ABC and unlabeled antibody (PAP) procedures . J Histochem Cytochem. 29:1981;577-580.
15. Landry J., Chretien P., Lambert H., Hickey E., Weber L.A. Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells. J Cell Biol. 109:1989;7-15.
16. Fertil B., Malaise E.P. Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors Analysis of 101 published survival curves . Int J Radiat Oncol Biol Phys. 11:1985;1699-1707.
17. Hall E.J. Radiobiology for the radiologist. 1994;JB Lippincott, Philadelphia.
18. Boreham D.R., Mitchel R.E. Regulation of heat and radiation stress responses in yeast by hsp-104. Radiat Res. 137:1994;190-195.
19. Peters L.J., Brock W.A., Chapman J.D., Wilson G. Predictive assays of tumor radiocurability. Am J Clin Oncol. 11:1988;275-287.
20. Ling C.C., Endlich B. Radioresistance induced by oncogenic transformation. Radiat Res. 120:1989;267-279.
21. McKenna W.G., Weiss M.C., Bakanauskas V.J., Sandler H., Kelsten M.L., Biaglow J., Tuttle S.W., Endlich B., Ling C.C., Muschel R.J. The role of the H-ras oncogene in radiation resistance and metastasis. Int J Radiat Oncol Biol Phys. 18:1990;849-859.
22. Bernhard E.J., McKenna W.G., Hamilton A.D., Sebti S.M., Qian Y., Wu J.M., Muschel R.J. Inhibiting Ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes. Cancer Res. 58:1998;1754-1761.
23. Kasid U., Pfeifer A., Brennan T., Beckett M., Weichselbaum R.R., Dritschilo A., Mark G.E. Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma. Science. 243:1998;1354-1356.
24. Fu K.K., Hammond E., Pajak T.F., Clery M., Doggett R.L., Byhardt R.W., McDonald S., Cooper J.S. Flow cytometric quantification of the proliferation-associated nuclear antigen p105 and DNA content in advanced head and neck cancers Results of RTOG 91-08 . Int J Radiat Oncol Biol Phys. 29:1994;661-671.
25. Struikmans H., Rutgers D.H., Hordijk G.J., Slootweg P.J., van der Tweel I., Battermann J.J. Prognostic significance of cell proliferation markers and DNA-ploidy in head and neck tumors. Int J Radiat Oncol Biol Phys. 40:1998;27-34.
26. Carmichael J., Hickson I.D. Keynote address Mechanisms of cellular resistance to cytotoxic drugs and X-irradiation . Int J Radiat Oncol Biol Phys. 20:1991;197-202.
27. Bristow R.G., Benchimol S., Hill R.P. The p53 gene as a modifier of intrinsic radiosensitivity Implications for radiotherapy . Radiother Oncol. 40:1996;197-223.
28. Domen J., Gandy K.L., Weissman I.L. Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood. 91:1998;2272-2282.
29. Huang A., Gandour-Edwards R., Rosenthal S.A., Siders D.B., Deitch A.D., White R.W. p53 and bcl-2 immunohistochemical alterations in prostate cancer treated with radiation therapy. Urology. 51:1998;346-351.
30. Mehlen P., Schulze-Osthoff K., Arrigo A.P. Small stress proteins as novel regulators of apoptosis Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death . J Biol Chem. 271:1996;16510-16514.
31. Samali A., Cotter T.G. Heat shock proteins increase resistance to apoptosis. Exp Cell Res. 223:1996;163-170.
32. Fisher G.A., Sidic B.I. Drug resistance in clinical oncology and hematology. Hematol Oncol Clin North Am. 9:(2):1995;239-506.
33. Moscow J.A., Cowan K.H. Multidrug resistance. J Natl Cancer Inst. 80:1988;14-20.
34. Rononson I.B. Molecular and cellular biology of multidrug resistance in tumor cells. 1991;Plenum Press, New York.
35. Tannock I.F., Godenberg G.J. Drug resistance and experimental chemotherapy. Tannock I.F., Hill R.P. The basic sciences of oncology. 1998;392 McGraw-Hill, Toronto.
36. Hospers G.A., Mulder N.H., de Vries E.G. Mechanisms of cellular resistance to cisplatin. Med Oncol Tumor Pharmacother. 5:1988;145-151.
37. Mitchell J.B., Gamson J., Russo A., Friedman N., DeGraff W., Carmichael J., Glatstein E. Chinese hamster pleiotropic multidrug-resistant cells are not radioresistant. NCI Monogr. 6:1988;187-191.
38. Shimm D.S., Olson S., Hill A.B. Radiation resistance in a multidrug resistant human T-cell leukemia line. Int J Radiat Oncol Biol Phys. 15:1988;931-936.
39. Denecke J., Fiedler K., Hacker-Klom U., Molenkamp G., Jurgens H., Wolff J.E. Multiple drug-resistant C6 glioma cells cross-resistant to irradiation. Anticancer Res. 17:1997;4531-4534.
40. Zhang K., Mack P., Wong K.P. Glutathione-related mechanisms in cellular resistance to anticancer drugs. Int J Oncol. 12:1998;871-882.
41. Pommier Y., Kerrigan D., Kohn K.W. Topoisomerase alterations associated with drug resistance in a line of Chinese hamster cells. NCI Monogr. 4:1987;87.
42. Ciocca D.R., Fuqua S.A., Lock-Lim S., Toft D.O., Welch W.J., McGuire W.L. Response of human breast cancer cells to heat shock and chemotherapeutic drugs. Cancer Res. 52:1992;3648-3654.
43. Richards E.H., Hickey E., Weber L., Master J.R. Effect of overexpression of the small heat shock protein HSP27 on the heat and drug sensitivities of human testis tumor cells. Cancer Res. 56:1996;2446-2451.
44. Huot J., Roy G., Lambert H., Chretien P., Landry J. Co-induction of HSP27 phosphorylation and drug resistance in Chinese hamster cells. Int J Oncol. 1:1992;31-36.
45. Huot J., Lambert H., Lavoie J.N., Guimond A., Houle F., Landry J. Characterization of 45-kDa/54-kDa HSP27 kinase, a stress-sensitive kinase which may activate the phosphorylation-dependent protective function of mammalian 27-kDa heat-shock protein HSP27. Eur J Biochem. 227:1995;416-427.
46. De Pooter C.M., Scalliet P.G., Elst H.J., Huybrechts J.J., Gheuens E.E., Van Oosterom A.T., Fichtinger-Schepman A.M., De Bruijn E.A. Resistance patterns between cis-diamminedichloroplatinum(II) and ionizing radiation. Cancer Res. 51:1991;4523-4527.
47. Warenius H.M., Seabra L.A., Maw P. Sensitivity to cis-diamminedichloroplatinum in human cancer cells is related to expression of cyclin D1 but not c-raf-1 protein. Int J Cancer. 67:1996;224-231.
48. Siddik Z.H., Mims B., Lozano G., Thai G. Independent pathways of p53 induction by cisplatin and X-rays in a cisplatin-resistant ovarian tumor cell line. Cancer Res. 58:1998;698-703.
49. Raaphorst G.P., Wang G., Wilkins D., Davis L., Bussey A., Stewart D., Ng C.E. Evaluation of cisplatin response in three radiation resistant and three radiation sensitive cell lines. Anticancer Res. 14:1994;1939-1942.
50. Bondy S.C. Ethanol toxicity and oxidative stress. Toxicol Lett. 63:1992;231-241.
51. Calabrese V., Renis M., Calderone A., Russo A., Barcellona M.L., Rizza V. Stress proteins and SH-groups in oxidant-induced cell damage after acute ethanol administration in rat. Free Radic Biol Med. 20:1996;391-397.
52. Loft S., Poulsen H.E. Cancer risk and oxidative DNA damage in man. J Mol Med. 74:1998;297-312.
53. Schnellmann R.G., Wiersma D.A., Randall D.J., Smith T.L., Sipes I.G. Hepatic mixed function oxygenase activity and glutathione S-transferase activity in mice following ethanol consumption and withdrawal. Toxicology. 32:1984;105-116.
54. Browman G.P., Wong G., Hodson I., Sathya J., Russell R., McAlpine L., Skingley P., Levine M.N. Influence of cigarette smoking on the efficacy of radiation therapy in head and neck cancer. N Engl J Med. 328:1993;159-163.