Use of Rab GTPases to study lipid trafficking in normal and sphingolipid storage disease fibroblasts

Methods in Enzymology

Volumn 403, Issue , 2005, Pages 166-182

  Choudhury, Amit ^a   Marks, David L ^a   Pagano, Richard E ^a  

^a MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; LIPID; RAB PROTEIN; SPHINGOLIPID;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CELL MEMBRANE; CELL TYPE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIAGNOSTIC VALUE; ENDOCYTOSIS; FIBROBLAST; FLUORESCENCE; GENE CONSTRUCT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LIPID TRANSPORT; METHODOLOGY; NONHUMAN; PLASMID; PRIORITY JOURNAL; STORAGE DISEASE; WILD TYPE;

ANIMALIA;

EID: 32344442834     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(05)03014-4     Document Type: Review

References (38)

1. Balch W.E., and Rothman J.E. Characterization of protein transport between successive compartments of the Golgi apparatus: Asymmetric properties of donor and acceptor activities in a cell-free system Arch. Biochem. Biophys. 240 1985 413 425
2. Campbell R.E., Tour O., Palmer A.E., Steinbach P.A., Baird G.S., Zacharias D.A., and Tsien R.Y. A monomeric red fluorescent protein Proc. Natl. Acad. Sci. USA 99 2002 7877 7882
3. Chen C.S., Martin O.C., and Pagano R.E. Changes in the spectral properties of a plasma membrane lipid analog during the first seconds of endocytosis in living cells Biophys. J. 72 1997 37 50
4. Choudhury A., Dominguez M., Puri V., Sharma D.K., Narita K., Wheatley C.W., Marks D.L., and Pagano R.E. Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells J. Clin. Invest. 109 2002 1541 1550
5. Choudhury A., Sharma D.K., Wheatley C.L., Marks D.L., and Pagano R.E. Abnormal sphingolipid recycling in Niemann Pick-A (NP-A) fibroblasts Mol. Biol. Cell 13S 2002 93a
6. Choudhury A., Sharma D.K., Marks D.L., and Pagano R.E. Elevated endosomal cholesterol levels in Niemann-Pick cells inhibit Rab4 and perturb membrane recycling Mol. Biol. Cell 15 2004 4500 4511
7. del Real G., Jimenez-Baranda S., Mira E., Lacalle R.A., Lucas P., Gomez-Mouton C., Alegret M., Pena J.M., Rodriguez-Zapata M., Alvarez-Mon M., Martinez A.C., and Manes S. Statins inhibit HIV-1 infection by down-regulating Rho activity J. Exp. Med. 200 2004 541 547
8. Hanada K., and Pagano R.E. A Chinese hamster ovary cell mutant defective in the non-endocytic uptake of fluorescent analogs of phosphatidylserine: Isolation using a cytosol acidification protocol J. Cell Biol. 128 1995 793 804
9. Hirosaki K., Yamashita T., Wada I., Jin H.Y., and Jimbow K. Tyrosinase and tyrosinase-related protein 1 require Rab7 for their intracellular transport J. Invest. Dermatol. 119 2002 475 480
10. Klein U., Gimpl G., and Fahrenholz F. Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor Biochemistry 34 1995 13784 13793
11. Lebrand C., Corti M., Goodson H., Cosson P., Cavalli V., Mayran N., Faure J., and Gruenberg J. Late endosome motility depends on lipids via the small GTPase Rab7 EMBO J. 21 2002 1289 1300
12. Leppimäki P., Kronvist R., and Slotte J.P. The rate of sphingomyelin synthesis de novo is influenced by the level of cholesterol in cultured human skin fibroblasts Biochem. J. 335 1998 285 291
13. Lim S.N., Bonzelius F., Low S.H., Wille H., Weimbs T., and Herman G.A. Identification of discrete classes of endosome-derived small vesicles as a major cellular pool for recycling membrane proteins Mol. Biol. Cell 12 2001 981 995
14. Martin O.C., and Pagano R.E. Internalization and sorting of a fluorescent analog of glucosylceramide to the Golgi apparatus of human skin fibroblasts: Utilization of endocytic and nonendocytic transport mechanisms J. Cell Biol. 125 1994 769 781
15. Martin O.C., Comly M.E., Blanchette-Mackie E.J., Pentchev P.G., and Pagano R.E. Cholesterol deprivation affects the fluorescence properties of a ceramide analog at the Golgi apparatus of living cells Proc. Natl. Acad. Sci. USA 90 1993 2661 2665
16. Narita K., Choudhury A., Dobrenis K., Sharma D., Holicky E., Marks D., Walkley S., and Pagano R. Protein transduction of Rab9 in Niemann-Pick cells reduces cholesterol storage FASEB J. 19 2005 1558 1561
17. Neufeld E.B., Wastney M., Patel S., Suresh S., Cooney A.M., Dwyer N.K., Roff C.F., Ohno K., Morris J.A., Carstea E.D., Incardona J.P., Strauss J.F. III, Vanier M.T., Patterson M.C., Brady R.O., Pentchev P.G., and Blanchette-Mackie E.J. The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo J. Biol. Chem. 274 1999 9627 9635
18. Olkkonen V.M., and Stenmark H. Role of Rab GTPases in membrane traffic Int. Rev. Cytol. 176 1997 1 85
19. Pagano R.E., and Sleight R.G. Defining lipid transport pathway in animal cells Science 229 1985 1051 1057
20. Pagano R.E., Martin O.C., Kang H.C., and Haugland R.P. A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: Accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor J. Cell Biol. 113 1991 1267 1279
21. Patterson M., Vanier M., Suzuki K., Morris J., Carstea E., Neufeld E., Blanchette-Machie E., and Pentchev P. Niemann-Pick disease type C: A lipid trafficking disorder C.R. Scriver A.L. Beaudet W.S. Sly D. Valle "The Metabolic and Molecular Bases of Inherited Disease" Vol. III 2001 McGraw Hill New York 3611 3634
22. Pfeffer S.R. Rab GTPases: Specifying and deciphering organelle identity and function Trends Cell Biol. 11 2001 487 491
23. Puri V., Watanabe R., Dominguez M., Sun X., Wheatley C.L., Marks D.L., and Pagano R.E. Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid storage diseases Nature. Cell Biol. 1 1999 386 388
24. Puri V., Watanabe R., Singh R.D., Dominguez M., Brown J.C., Wheatley C.L., Marks D.L., and Pagano R.E. Clathrin-dependent and -independent internalization of plasma membrane sphingolipids initiates two Golgi targeting pathways J. Cell Biol. 154 2001 535 547
25. Puri V., Jefferson J.R., Singh R.D., Wheatley C.L., Marks D.L., and Pagano R.E. Sphingolipid storage induces accumulation of intracellular cholesterol by stimulating SREBP-1 cleavage J. Biol. Chem. 278 2003 20961 20970
26. Scriver C.R., Beaudet A.L., Sly W.S., and Valle D.D. Part 16: Lysosomal enzymes C.R. Scriver A.L. Beaudet W.S. Sly D. Valle "The Metabolic and Molecular Bases of Inherited Disease" Vol. III 2001 McGraw-Hill New York 3371 3894
27. Seabra M.C., Mules E.H., and Hume A.N. Rab GTPases, intracellular traffic and disease Trends Mol. Med. 8 2002 23 30
28. Segev N. Ypt and Rab GTPases: Insight into functions through novel interactions Curr. Opin. Cell Biol. 13 2001 500 511
29. Shapiro A.D., Riederer M.A., and Pfeffer S.R. Biochemical analysis of rab9, a ras-like GTPase involved in protein transport from late endosomes to the trans Golgi network J. Biol. Chem. 268 1993 6925 6931
30. Sharma D.K., Choudhury A., Singh R.D., Wheatley C.L., Marks D.L., and Pagano R.E. Glycosphingolipids internalized via caveolar-related endocytosis rapidly merge with the clathrin pathway in early endosomes and form microdomains for recycling J. Biol. Chem. 278 2003 7564 7572
31. Sharma D.K., Brown J.C., Choudhury A., Peterson T.E., Holicky E., Marks D.L., Simari R., Parton R.G., and Pagano R.E. Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol Mol. Biol. Cell 15 2004 3114 3122
32. Singh R.D., Puri V., Valiyaveettil J.T., Marks D.L., Bittman R., and Pagano R.E. Selective caveolin-1-dependent endocytosis of glycosphingolipids Mol. Biol. Cell 14 2003 3254 3265
33. Stein M.-P., Dong J., and Wandinger-Ness A. Rab proteins and endocytic trafficking: Potential targets for therapeutic intervention Adv. Drug Deliv. Rev. 55 2003 1421 1437
34. Stenmark H., and Olkkonen V.M. The Rab GTPase family Genome Biol. 2 2001 review S3007.
35. Stenmark H., Parton R.G., Steele-Mortimer O., Lutcke A., Gruenberg J., and Zerial M. Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis EMBO J. 13 1994 1287 1296
36. Sturley S.L., Patterson M.C., Balch W., and Liscum L. The pathophysiology and mechanisms of NP-C disease Biochim. Biophys. Acta 1685 2004 83 87
37. Troost J., Lindenmaier H., Haefeli W.E., and Weiss J. Modulation of cellular cholesterol alters P-glycoprotein activity in multidrug-resistant cells Mol. Pharmacol. 66 2004 1332 1339
38. Zerial M., and McBride H. Rab proteins as membrane organizers Nat. Rev. Mol. Cell Biol. 2 2001 107 117