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Volumn 23, Issue 13, 2003, Pages 5536-5544

Glucocorticoids play a fundamental role in protecting the brain during innate immune response

Author keywords

Caspases; Cytokines; Gram negative cell wall component; Inflammation; Innate immunity; Microglia; Neurodegeneration; NF B; TNF

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CASPASE; ENDOTOXIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR ANTAGONIST; MIFEPRISTONE; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0038722154     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-13-05536.2003     Document Type: Article
Times cited : (168)

References (28)
  • 1
    • 0035487313 scopus 로고    scopus 로고
    • Cytokines and acute neurodegeneration
    • Allan SM, Rothwell NJ (2001) Cytokines and acute neurodegeneration. Nat Rev Neurosci 2:734-744.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 734-744
    • Allan, S.M.1    Rothwell, N.J.2
  • 2
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
    • Beg AA, Baltimore D (1996) An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274:782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 3
    • 0033725002 scopus 로고    scopus 로고
    • Signaling by the TNF receptor superfamily and T cell homeostasis
    • Chan FK, Siegel RM, Lenardo MJ (2000) Signaling by the TNF receptor superfamily and T cell homeostasis. Immunity 13:419-422.
    • (2000) Immunity , vol.13 , pp. 419-422
    • Chan, F.K.1    Siegel, R.M.2    Lenardo, M.J.3
  • 4
    • 0031459881 scopus 로고    scopus 로고
    • Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation
    • De Bosscher K, Schmitz ML, Vanden Berghe W, Plaisance S, Fiers W, Haegeman G (1997) Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation. Proc Natl Acad Sci USA 94:13504-13509.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13504-13509
    • De Bosscher, K.1    Schmitz, M.L.2    Vanden Berghe, W.3    Plaisance, S.4    Fiers, W.5    Haegeman, G.6
  • 5
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh S, Karin M (2002) Missing pieces in the NF-kappaB puzzle. Cell [Suppl] 109:S81-96.
    • (2002) Cell [Suppl] , vol.109
    • Ghosh, S.1    Karin, M.2
  • 6
    • 0034663946 scopus 로고    scopus 로고
    • Central nervous system-initiated inflammation and neurotrophism in trauma: IL-lbeta is required for the production of ciliary neurotrophic factor
    • Herx LM, Rivest S, Yong VW (2000) Central nervous system-initiated inflammation and neurotrophism in trauma: IL-lbeta is required for the production of ciliary neurotrophic factor. J Immunol 165:2232-2239.
    • (2000) J Immunol , vol.165 , pp. 2232-2239
    • Herx, L.M.1    Rivest, S.2    Yong, V.W.3
  • 7
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the cross-roads of life and death
    • Karin M, Lin A (2002) NF-kappaB at the cross-roads of life and death. Nat Immunol 3:221-227.
    • (2002) Nat Immunol , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 8
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • Kawai T, Adachi O, Ogawa T, Takeda K, Akira S (1999) Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11:115-122.
    • (1999) Immunity , vol.11 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 9
    • 0033038790 scopus 로고    scopus 로고
    • Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappa B alpha within specific cellular populations of the rat brain
    • Laflamme N, Rivest S (1999) Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappa B alpha within specific cellular populations of the rat brain. J Neurochem 73:309-321.
    • (1999) J Neurochem , vol.73 , pp. 309-321
    • Laflamme, N.1    Rivest, S.2
  • 10
    • 0035170282 scopus 로고    scopus 로고
    • Toll-like receptor 4: The missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components
    • Laflamme N, Rivest S (2001) Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. FASEB J 15:155-163.
    • (2001) FASEB J , vol.15 , pp. 155-163
    • Laflamme, N.1    Rivest, S.2
  • 11
    • 0033573451 scopus 로고    scopus 로고
    • An essential role of interleukin-1β in mediating NF-κB activity and COX-2 transcription in cells of the blood-brain barrier in response to systemic and localized inflammation, but not during endotoxemia
    • Laflamme N, Lacroix S, Rivest S (1999) An essential role of interleukin-1β in mediating NF-κB activity and COX-2 transcription in cells of the blood-brain barrier in response to systemic and localized inflammation, but not during endotoxemia. J Neurosci 19:10923-10930.
    • (1999) J Neurosci , vol.19 , pp. 10923-10930
    • Laflamme, N.1    Lacroix, S.2    Rivest, S.3
  • 12
    • 0034765855 scopus 로고    scopus 로고
    • Circulating cell wall components derived from gram-negative and not gram-positive bacteria cause a profound transcriptional activation of the gene encoding toll-like receptor 2 in the CNS
    • Laflamme N, Souci G, Rivest S (2001) Circulating cell wall components derived from gram-negative and not gram-positive bacteria cause a profound transcriptional activation of the gene encoding toll-like receptor 2 in the CNS. J Neurochem 70:648-657.
    • (2001) J Neurochem , vol.70 , pp. 648-657
    • Laflamme, N.1    Souci, G.2    Rivest, S.3
  • 13
    • 0033304494 scopus 로고    scopus 로고
    • Molecular control of immune/inflammatory responses: Interactions between nuclear factor-kappa B and steroid receptor-signaling pathways
    • McKay LI, Cidlowski JA (1999) Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathways. Endocr Rev 20:435-459.
    • (1999) Endocr Rev , vol.20 , pp. 435-459
    • McKay, L.I.1    Cidlowski, J.A.2
  • 14
    • 0034193376 scopus 로고    scopus 로고
    • Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and NF-κB activity in the brain during endotoxemia
    • Nadeau S, Rivest S (2000) Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and NF-κB activity in the brain during endotoxemia. J Neurosci 20:3456-3468.
    • (2000) J Neurosci , vol.20 , pp. 3456-3468
    • Nadeau, S.1    Rivest, S.2
  • 15
    • 0035377576 scopus 로고    scopus 로고
    • The complement system is an integrated part of the naturalinnate immune response in the brain
    • Nadeau S, Rivest S (2001) The complement system is an integrated part of the naturalinnate immune response in the brain. FASEB J 15:1410-1412.
    • (2001) FASEB J , vol.15 , pp. 1410-1412
    • Nadeau, S.1    Rivest, S.2
  • 16
    • 0037105511 scopus 로고    scopus 로고
    • Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: Role of glucocorticoids and CD14
    • Nadeau S, Rivest S (2002) Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: role of glucocorticoids and CD14. J Immunol 169:3370-3381.
    • (2002) J Immunol , vol.169 , pp. 3370-3381
    • Nadeau, S.1    Rivest, S.2
  • 17
    • 0034765498 scopus 로고    scopus 로고
    • Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: No requirement for proapoptotic interleukin-1beta in neurodegeneration
    • Nguyen MD, Julien JP, Rivest S (2001) Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration. Ann Neurol 50:630-639.
    • (2001) Ann Neurol , vol.50 , pp. 630-639
    • Nguyen, M.D.1    Julien, J.P.2    Rivest, S.3
  • 18
    • 0036518997 scopus 로고    scopus 로고
    • Innate immunity: The missing link in neuroprotection and neurodegeneration?
    • Nguyen MD, Julien JP, Rivest S (2002) Innate immunity: the missing link in neuroprotection and neurodegeneration? Nat Rev Neurosci 3:216-227.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 216-227
    • Nguyen, M.D.1    Julien, J.P.2    Rivest, S.3
  • 19
    • 0034534995 scopus 로고    scopus 로고
    • Interleukin 1 in the brain: Biology, pathology and therapeutic target
    • Rothwell NJ, Luheshi GN (2000) Interleukin 1 in the brain: biology, pathology and therapeutic target. Trends Neurosci 23:618-625.
    • (2000) Trends Neurosci , vol.23 , pp. 618-625
    • Rothwell, N.J.1    Luheshi, G.N.2
  • 20
    • 0029739502 scopus 로고    scopus 로고
    • Why stress is bad for your brain
    • Sapolsky RM (1996) Why stress is bad for your brain. Science 273:749-750.
    • (1996) Science , vol.273 , pp. 749-750
    • Sapolsky, R.M.1
  • 21
    • 0034913224 scopus 로고    scopus 로고
    • To B or not to B: TNF family signaling in lymphocytes
    • Siegel RM, Lenardo MJ (2001) To B or not to B: TNF family signaling in lymphocytes. Nat Immunol 2:577-578.
    • (2001) Nat Immunol , vol.2 , pp. 577-578
    • Siegel, R.M.1    Lenardo, M.J.2
  • 23
    • 0022382737 scopus 로고
    • Recombinant human tumor necrosis factor-alpha: Effects on proliferation of normal and transformed cells in vitro
    • Sugarman BJ, Aggarwal BB, Hass PE, Figari IS, Palladino MA Jr, Shepard HM (1985) Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science 230:943-945.
    • (1985) Science , vol.230 , pp. 943-945
    • Sugarman, B.J.1    Aggarwal, B.B.2    Hass, P.E.3    Figari, I.S.4    Palladino M.A., Jr.5    Shepard, H.M.6
  • 24
    • 0035844702 scopus 로고    scopus 로고
    • Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines
    • Thibeault I, Laflamme N, Rivest S (2001) Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines. J Comp Neurol 434:461-477.
    • (2001) J Comp Neurol , vol.434 , pp. 461-477
    • Thibeault, I.1    Laflamme, N.2    Rivest, S.3
  • 26
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang CY, Mayo MW, Baldwin AS Jr (1996) TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science 274:784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin A.S., Jr.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.