Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS

Journal of Medicinal Chemistry

Volumn 49, Issue 3, 2006, Pages 1140-1148

  Cho, Jong Hyun ^a   Bernard, Dale L ^b   Sidwell, Robert W ^b   Kern, Earl R ^c   Chu, Chung K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UTAH STATE UNIVERSITY   (United States)

^c UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4,5 DIHYDROXY 3 HYDROXYMETHYLCYCLOPENTEN 2 ENYL) 1H 1,2,3 TRIAZOLE 4 CARBOXYLIC ACID AMIDE; 1 (4,5 DIHYDROXY 3 HYDROXYMETHYLCYCLOPENTEN 2 ENYL) 1H 1,2,4 TRIAZOLE 3 CARBOXYLIC ACID AMIDE; 2,2 DIMETHOXY 6 TRITYLOXYMETHYL 4,6A DIHYDRO 3AH CYCLOPENTA[1,3]DIOXOL 4 OL; ALLYL COMPOUND; ANTIVIRUS AGENT; CARBOCYCLIC NUCLEOSIDE; CYCLOPENTENE DERIVATIVE; HETEROCYCLIC COMPOUND; HYDROXYL GROUP; RIBOSE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CATALYST; CHIRALITY; CONCENTRATION RESPONSE; COWPOX VIRUS; DRUG POTENCY; DRUG SYNTHESIS; NONHUMAN; ORTHOPOXVIRUS; QUANTUM YIELD; REACTION ANALYSIS; RING CLOSING METATHESIS; SARS CORONAVIRUS; STRUCTURE ACTIVITY RELATION; VACCINIA VIRUS; VENEZUELAN EQUINE ENCEPHALOMYELITIS ALPHAVIRUS; WEST NILE FLAVIVIRUS; YELLOW FEVER FLAVIVIRUS;

ANTIVIRAL AGENTS; NUCLEOSIDES; ORTHOPOXVIRUS; RIBOSE; SARS VIRUS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 32344433894     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0509750     Document Type: Article

References (65)

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