Asymmetric synthesis and antiviral activities of L-carbocyclic 2',3'- didehydro-2',3'-dideoxy and 2',3'-dideoxy nucleosides

Journal of Medicinal Chemistry

Volumn 42, Issue 17, 1999, Pages 3390-3399

  Wang, Peiyuan ^a   Gullen, Beth ^b   Newton, M Gary ^a   Cheng, Yung Chi ^b   Schinazi, Reymond F ^c   Chu, Chung K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOCYCLIC 2',3' DIDEHYDRO 2',3' DIDEOXYADENOSINE; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG CONFORMATION; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; REACTION ANALYSIS; REDUCTION;

ADENOSINE; ANIMALS; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; HEPATITIS B VIRUS; HIV-1; INHIBITORY CONCENTRATION 50; LEUKOCYTES, MONONUCLEAR; MOLECULAR CONFORMATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033606989     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9901327     Document Type: Article

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40. 21(#4); Z = 4.