Disruption of ShcA signaling halts cell proliferation - Characterization of ShcC residues that influence signaling pathways using yeast

Cellular Signalling

Volumn 18, Issue 6, 2006, Pages 795-806

  Heinrich, Julia N ^a   Kwak, Seung P ^a   Howland, David S ^a   Chen, Jin ^a   Sturner, Stephen ^a   Sullivan, Kelly ^a   Lipinski, Kerri ^a   Cheng, Ke Yi ^a   She, Yijin ^a   Lo, Frederick ^a   Ghavami, Afshin ^a  

^a PFIZER INC   (United States)

Author keywords

Grb2; Knockdown; MAPK; Ras; Shc; shRNA; Trk; Yeast

Indexed keywords

AMINO ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP; GLUTATHIONE TRANSFERASE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; HYBRID PROTEIN; MESSENGER RNA; PHOSPHOTRANSFERASE; PROTEIN SH2; PROTEIN SHC; PROTEIN SHCA; PROTEIN SHCC; RAS PROTEIN; RNA; SOS PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CELL PROLIFERATION; CELL STRAIN HEK293; CELL TRANSFORMATION; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FUNGUS GROWTH; FUNGUS MUTANT; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR PROBE; MUTATIONAL ANALYSIS; MYRISTYLATION; NONHUMAN; PHENOTYPE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TEMPERATURE SENSITIVE MUTANT; VALIDATION STUDY; WESTERN BLOTTING; YEAST; YEAST CELL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL DIVISION; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; FUNGAL PROTEINS; GENE TRANSFER TECHNIQUES; GENETIC COMPLEMENTATION TEST; GRB2 ADAPTOR PROTEIN; HUMANS; NEUROPEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; RECEPTOR, TRKB; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

FUNGI; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 32144439694     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2005.07.004     Document Type: Article

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