Requirement for Shc in TCR-mediated activation of a T cell hybridoma

Journal of Immunology

Volumn 163, Issue 5, 1999, Pages 2586-2591

  Pratt, Joanne C ^a   Van Den Brink, Marcel R M ^a,b   Igras, Vivien E ^a   Walk, Scott F ^c   Ravichandran, Kodimangalam S ^c   Burakoff, Steven J ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; FAS LIGAND; INTERLEUKIN 2; PHENYLALANINE; T LYMPHOCYTE RECEPTOR; TYROSINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FATE; CELL PROLIFERATION; CELL TRANSFORMATION; CYTOKINE PRODUCTION; HYBRIDOMA; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIGENS, CD95; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; FAS LIGAND PROTEIN; GRB2 ADAPTOR PROTEIN; HYBRIDOMAS; INTERLEUKIN-2; LIGANDS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MUTATION; PHOSPHORYLATION; POINT MUTATION; PROTEIN BIOSYNTHESIS; PROTEINS; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL; SRC HOMOLOGY DOMAINS; T-LYMPHOCYTES; TRANSFECTION;

EID: 0033197926     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Pelicci, G., L. Lanfrancone, F. Grignani, J. McGlade, F. Cavallo, G. Forni, I. Nicoletti, T. Pawson, and P. G. Pelicci. 1992. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell 70:93.
2. Gotoh, N., A. Tojo, and M. Shibuya. 1995. A novel She to Myc pathway through which IL3 signals to inhibit apoptosis of hematopoietic cells. Blood 86:153a.
3. Gotoh, N., A. Tojo, and M. Shibuya. 1996. A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3. EMBO J. 15:6197.
4. Ravichandran, K. S., U. Lorenz, S. E. Shoelson, and S. J. Burakoff. 1995. Interaction of She with Grb2 regulates association of Grb2 with mSOS. Mol. Cell. Biol. 15:593.
5. Ravichandran, K. S., K. K. Lee, Z. Songyang, L. C. Cantley, P. Burn, and S. J. Burakoff. 1993. Interaction of She with the ζ chain of the T cell receptor upon T cell activation. Science 262:902.
6. Osman, N., S. C. Lucas, H. Turner, and D. Cantrell 1995. A comparison of the interaction of She and the tyrosine kinase ZAP-70 with the T cell antigen receptor ζ chain tyrosine-based activation motif. J. Biol. Chem. 270:13981.
7. Marengere, L. E. M., P. Waterhouse, G. S. Duncan, H.-W. Mittrucker, G.-S. Feng, and T. W. Mak. 1996. Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science 272:1170.
8. Pratt, J. C., M Weiss, C. A. Sieff, S. E. Shoelson, S. J. Burakoff, and K. S. Ravichandran. 1996. Evidence for a physical association between the Shc-PTB domain and the bc chain of the granulocyte-macrophage colony-stimulating factor receptor. J. Biol. Chem. 271:12137.
9. Zhou, M. M., K. S. Ravichandran, E. T. Olejniczak, A. M. Petros, R. P. Meadows, M. Sattler, J. E. Harlan, W. S. Wade, S. J. Burakoff, and S. W. Fesik. 1995. Structure and ligand recognition of the phosphotyrosine binding domain of Shc. Nature 378:584.
10. Haskins, K., R. Kubo, J. White, M. Pigeon, J. Kappler, and P. Marrack. 1983. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J. Exp. Med. 157:1149.
11. + B cell hybridomas to H-2-restricted T cell hybridomas. Proc. Natl. Acad. Sci. USA 79:3604.
12. Nicoletti, I., G. Migliorati, M. C. Pagliacci, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139:271.
13. Ju, S.-T., D. J. Panka, H. Cui, R. Ettinger, M. El-Khatib, D. H. Sherr, B. Z. Stanger, and A. Marshak-Rothstein. 1995. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 373:444.
14. Ashwell, J. D., R. E. Cunningham, P. D. Noguchi, and D. Hernandez. 1987. Cell growth block of T cell hybridomas upon activation with antigen. J. Exp. Med. 165:173.
15. Baldari, C., G. Pelicci, M. DiSomma, E. Milia, S. Giuli, P. Pelicci, and J. Telford. 1995. Inhibition Of CD4/p56Lck signaling by a dominant negative mutant of the Shc adaptor protein. Oncogene 10:1141.
16. Van Parijs, L., A. Ibraghimov, and A. Abbas. 1996. The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 3:321.
17. Sasaoka, T., W. J. Langlois, J. W. Leitner, B. Draznin, and J. M. Olefsky. 1994. The signaling pathway coupling epidermal growth factor receptors to activation of p21ras. J. Biol. Chem. 269:32621.
18. Gotoh, N., K. Muroya, S. Hattori, S. Nakamura, K. Chida, and M. Shibuya. 1995. The SH2 domain of She suppresses EGF-induced mitogenesis in a dominant negative manner. Oncogene 11:2525.
19. Walk, S. F., M. E. March, and K. S. Ravichandran. 1998. Roles of Lck, Syk and Zap-70 tyrosine kinases in T cell receptor-mediated phosphorylation of the adapter protein Shc. Eur. J. Immunol. 28:2265.
20. Ravichandran, K. S., M.-M. Zhou, J. C. Pratt, J. E. Harlan, S. F. Walk, S. W. Fesik, and S. J. Burakoff. 1997. Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo. Mol. Cell. Biol. 17:5540.
21. Van Parijs, L., and A. Abbas. 1998. Homeostasis and self-tolerance in the immune system: turning lymphocytes off. Science 280:243.
22. Gotoh, N., M. Toyoda, and M. Shibuya. 1997. Tyrosine phosphorylation sites at amino acids 239 and 240 of She are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation. Mol. Cell. Biol. 17:1824.
23. Wary, K. K., F. Mainiero, S. J. Isakoff, E. E. Marcantonio, and F. G. Giancotti. 1996. The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell 87:733.
24. lck in T-cell receptor/CD3-mediated apoptosis and Fas-ligand induction in Jurkat cells. Biochem. Biophys. Res. Commun. 213:994.
25. Eischen, C., B. Williams, W. Zhang, L. Samelson, D. Lynch, R. Abraham, and P. Leibson. 1997. Zap-70 tyrosine kinase is required for the up-regulation of Fas ligand in activation-induced T cell apoptosis. J. Immunol. 159:1135.
26. Holtz-Heppelmann, C. J., A. Algeciras, A. D. Badley, and C. V. Paya. 1998. Transcriptional regulation of the human FasL promoter-enhancer region. J. Biol. Chem. 273:4416.
27. Latinis, K. M., L. L. Carr, E. J. Peterson, L. A. Norian, S. L. Eliason, and G. A. Koretzky. 1997. Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events. J. Immunol. 158:4602.
28. Sahuquillo, A. G., A. Roumier, E. Teixeiro, R. Bragado, and B. Alarcon. 1998. T cell receptor (TCR) engagement in apoptosis-defective, but interleukin-2 (IL-2)-producing, T cells results in impaired ZAP70/CD3-z association. J. Exp. Med. 187:1179.
29. Green, D., and D. Scott. 1994. Activation-induced apoptosis in lymphocytes. Curr. Opin. Immunol. 6:476.
30. Harmer, S., and A. DeFranco. 1997. Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes. Mol. Cell. Biol. 17:4087.
31. Northrop, J. P., M. J. Pustelnik, A. T. Lu, and J. R. Grove. 1996. Characterization of the roles of SH2 domain-containing proteins in T-lymphocyte activation using dominant negative SH2 domains. Mol. Cell. Biol. 16:2255.
32. Buday, L., S. E. Egan, P. R. Viciana, D. A. Cantrell, and J. Downward. 1994. A complex of Grb2 adapator protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in Ras activation in T cells. J. Biol. Chem. 269:9019.
33. Zhang, W., J. Sloan-Lancaster, J. Kitchen, R. P. Trible, and L. E. Samelson. 1998. LAT: The Zap-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92:83.
34. Wu, J., D. G. Motto, G. A. Koretzky, and A. Weiss. 1996. Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity 4:593.
35. Liu, S. K., N. Fang, G. A. Koretzky, and C. J. McGlade. 1999. The hematopoietic-specific adaptor protein Gads functions in T-cell signaling via interactions with SLP-76 and LAT adaptors. Curr. Biol. 9:67.
36. ras regulatory pathways coexist in T cells. Mol. Cell. Biol. 12:3305.
37. Crabtree, G. R. 1989. Contingent genetic regulatory events in T lymphocyte activation. Science 243:355.
38. Latinis, K. M., L. A. Norian, S. L. Eliason, and G. A. Korelzky. 1997. Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells. J. Biol. Chem. 272:31427.
39. Mittelstadt, P. R., and J. D. Ashwell. 1998. Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression. Mol. Cell. Biol. 18:3744.
40. Matsui, K., A. Fine, B. Zhu, A. Marshak-Rothstein, and S.-T. Ju. 1998. Identification of two NF-κB sites in mouse CD95 ligand (Fas ligand) promoter: functional analysis in T cell hybridoma. J. Immunol. 161:3469.
41. Norian, L. A., K. M. Latinis, and G. A. Koretzky. 1998. A newly identified response element in the CD95 ligand promoter contributes to optimal inducibility in activated T lymphocytes. J Immunol. 161:1078.