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Volumn 71, Issue 6, 2006, Pages 722-734

Suppression of survival in human SKBR3 breast carcinoma in response to metal-chelator complexes is preferential for copper-dithiocarbamate

Author keywords

Anti oxidant enzymes; cis Platin; Glutathione; H 2DCFDA; Ros production

Indexed keywords

8 QUINOLINOL; ACETYLCYSTEINE; ANTIOXIDANT; CATALASE; CISPLATIN; COPPER COMPLEX; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; DIETHYLDITHIOCARBAMIC ACID; DIMETHYL SULFOXIDE; DITHIOCARBAMIC ACID DERIVATIVE; GLUTATHIONE; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; MANNITOL; METAL CHELATE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TRANSCRIPTION FACTOR SP1; ZINC COMPLEX;

EID: 32144433858     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.11.028     Document Type: Article
Times cited : (26)

References (47)
  • 1
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • C.B. Thompson Apoptosis in the pathogenesis and treatment of disease Science 267 1995 1456 1462
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 2
    • 0028147329 scopus 로고
    • Inhibition of activation-induced death in T cell hybridomas by thiol antioxidants: Oxidative stress as a mediator of apoptosis
    • P.A. Sandstrom, M.D. Mannie, and T.M. Buttke Inhibition of activation-induced death in T cell hybridomas by thiol antioxidants: oxidative stress as a mediator of apoptosis J Leukoc Biol 55 1994 221 226
    • (1994) J Leukoc Biol , vol.55 , pp. 221-226
    • Sandstrom, P.A.1    Mannie, M.D.2    Buttke, T.M.3
  • 3
    • 0028072422 scopus 로고
    • Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor B (NF-B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes
    • R. Bessho, K. Matsubara, M. Kubota, K. Kuwakado, H. Hirota, and Y. Wakazono Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor B (NF-B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes Biochem Pharmacol 48 1994 1883 1889
    • (1994) Biochem Pharmacol , vol.48 , pp. 1883-1889
    • Bessho, R.1    Matsubara, K.2    Kubota, M.3    Kuwakado, K.4    Hirota, H.5    Wakazono, Y.6
  • 4
    • 0030663670 scopus 로고    scopus 로고
    • Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: A p53-independent induction of p21WAF1/CIP1 via C/EBPβ
    • R. Chinery, J.A. Brockman, M.O. Peeler, Y. Shyr, R.D. Beauchamp, and R.J. Coffey Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPβ Nat Med 3 1997 1233 1241
    • (1997) Nat Med , vol.3 , pp. 1233-1241
    • Chinery, R.1    Brockman, J.A.2    Peeler, M.O.3    Shyr, Y.4    Beauchamp, R.D.5    Coffey, R.J.6
  • 5
    • 13344279414 scopus 로고    scopus 로고
    • Induction of apoptosis by pyrrolidine dithiocarbamate and N-acetylcysteine in vascular smooth muscle cells
    • J.C. Tsai, M. Jain, C.M. Hsieh, W.S. Lee, M. Yoshizumi, and C. Patterson Induction of apoptosis by pyrrolidine dithiocarbamate and N-acetylcysteine in vascular smooth muscle cells J Biol Chem 271 1996 3667 3670
    • (1996) J Biol Chem , vol.271 , pp. 3667-3670
    • Tsai, J.C.1    Jain, M.2    Hsieh, C.M.3    Lee, W.S.4    Yoshizumi, M.5    Patterson, C.6
  • 6
    • 0028815621 scopus 로고
    • Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper
    • C.S.I. Nobel, M. Kimland, B. Lind, S. Orrenius, and A.F.G. Slater Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper J Biol Chem 270 1995 26202 26208
    • (1995) J Biol Chem , vol.270 , pp. 26202-26208
    • Nobel, C.S.I.1    Kimland, M.2    Lind, B.3    Orrenius, S.4    Slater, A.F.G.5
  • 7
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor κb activation in intact cells
    • R. Schreck, B. Meier, D.N. Mannel, W. Droge, and P.A. Baeuerle Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells J Exp Med 175 1992 1181 1194
    • (1992) J Exp Med , vol.175 , pp. 1181-1194
    • Schreck, R.1    Meier, B.2    Mannel, D.N.3    Droge, W.4    Baeuerle, P.A.5
  • 8
    • 0032908620 scopus 로고    scopus 로고
    • Zinc is required in pyrrolidine dithiocarbamate inhibition of NF-κB
    • C.H. Kim, J.H. Kim, C.Y. Hsu, and Y.S. Ahn Zinc is required in pyrrolidine dithiocarbamate inhibition of NF-κB FEBS Lett 449 1999 28 32
    • (1999) FEBS Lett , vol.449 , pp. 28-32
    • Kim, C.H.1    Kim, J.H.2    Hsu, C.Y.3    Ahn, Y.S.4
  • 9
    • 0033916920 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu(2+) and Zn(2+)
    • W. Erl, C. Weber, and G.K. Hansson Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu(2+) and Zn(2+) Am J Physiol Cell Physiol 278 2000 C1116 C1125
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Erl, W.1    Weber, C.2    Hansson, G.K.3
  • 10
    • 0347461147 scopus 로고    scopus 로고
    • PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: Involvement of p38 mitogen activated protein kinase
    • S.K. Moon, S.Y. Jung, Y.H. Choi, Y.C. Lee, C. Patterson, and C.H. Kim PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: involvement of p38 mitogen activated protein kinase J Cell Physiol 198 2 2004 310 323
    • (2004) J Cell Physiol , vol.198 , Issue.2 , pp. 310-323
    • Moon, S.K.1    Jung, S.Y.2    Choi, Y.H.3    Lee, Y.C.4    Patterson, C.5    Kim, C.H.6
  • 11
    • 0024413886 scopus 로고
    • Myeloprotective effect of diethyldithiocarbamate treatment following 1,3-bis-(2-chloroethyl)-1-nitrosourea, adriamycin, or mitomycin C in mice
    • T.K. Schmalbach, and R.F. Borch Myeloprotective effect of diethyldithiocarbamate treatment following 1,3-bis-(2-chloroethyl)-1- nitrosourea, adriamycin, or mitomycin C in mice Cancer Res 49 1989 2574 2577
    • (1989) Cancer Res , vol.49 , pp. 2574-2577
    • Schmalbach, T.K.1    Borch, R.F.2
  • 12
    • 0025063641 scopus 로고
    • Mechanism of diethyldithiocarbamate modulation of murine bone marrow toxicity
    • T.K. Schmalbach, and R.F. Borch Mechanism of diethyldithiocarbamate modulation of murine bone marrow toxicity Cancer Res 50 1990 6218 6221
    • (1990) Cancer Res , vol.50 , pp. 6218-6221
    • Schmalbach, T.K.1    Borch, R.F.2
  • 13
    • 0026707698 scopus 로고
    • Diethyldithiocarbamate induction of cytokine release in human long-term bone marrow cultures
    • C.J. East, C. Abboud, and R.F. Borch Diethyldithiocarbamate induction of cytokine release in human long-term bone marrow cultures Blood 80 1992 1172 1177
    • (1992) Blood , vol.80 , pp. 1172-1177
    • East, C.J.1    Abboud, C.2    Borch, R.F.3
  • 15
    • 11144224746 scopus 로고    scopus 로고
    • Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells
    • D. Cen, B. Brayton, B. Shahandeh, F.L. Meyskens Jr., and P.J. Farmer Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells J Med Chem 27 2004 6914 6920
    • (2004) J Med Chem , vol.27 , pp. 6914-6920
    • Cen, D.1    Brayton, B.2    Shahandeh, B.3    Meyskens Jr., F.L.4    Farmer, P.J.5
  • 16
    • 0037902555 scopus 로고    scopus 로고
    • Melanin as a target for melanoma chemotherapy: Pro-oxidant effect of oxygen and metals on melanoma variability
    • P.J. Farmer, S. Gidanian, B. Shahandeh, A.J. Di Bilio, N. Tohidian, and F.L. Meyskens Melanin as a target for melanoma chemotherapy: pro-oxidant effect of oxygen and metals on melanoma variability Pigment Cell Res 16 2003 273 279
    • (2003) Pigment Cell Res , vol.16 , pp. 273-279
    • Farmer, P.J.1    Gidanian, S.2    Shahandeh, B.3    Di Bilio, A.J.4    Tohidian, N.5    Meyskens, F.L.6
  • 17
    • 21344440550 scopus 로고    scopus 로고
    • Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis
    • D. Chen, F. Peng, Q.C. Cui, K.G. Daniel, S. Orlu, and J. Liu Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis Front Biosci 10 2005 2932 2939
    • (2005) Front Biosci , vol.10 , pp. 2932-2939
    • Chen, D.1    Peng, F.2    Cui, Q.C.3    Daniel, K.G.4    Orlu, S.5    Liu, J.6
  • 18
    • 1542270307 scopus 로고    scopus 로고
    • Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells
    • K.G. Daniel, P. Gupta, R.H. Harbach, W.C. Guida, and Q.P. Dou Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells Biochem Pharmacol 67 2004 1139 1151
    • (2004) Biochem Pharmacol , vol.67 , pp. 1139-1151
    • Daniel, K.G.1    Gupta, P.2    Harbach, R.H.3    Guida, W.C.4    Dou, Q.P.5
  • 19
    • 0035923248 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the 3′untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare
    • R. Kumar, J. Smeds, P. Berggren, O. Straume, B.L. Rozell, and L.A. Akslen A single nucleotide polymorphism in the 3′untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare Int J Cancer 95 2001 388 393
    • (2001) Int J Cancer , vol.95 , pp. 388-393
    • Kumar, R.1    Smeds, J.2    Berggren, P.3    Straume, O.4    Rozell, B.L.5    Akslen, L.A.6
  • 20
    • 0035866772 scopus 로고    scopus 로고
    • Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer
    • S. Geisler, P.E. Lonning, T. Aas, H. Johnsen, O. Fluge, and D.F. Haugen Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer Cancer Res 61 2001 2505 2512
    • (2001) Cancer Res , vol.61 , pp. 2505-2512
    • Geisler, S.1    Lonning, P.E.2    Aas, T.3    Johnsen, H.4    Fluge, O.5    Haugen, D.F.6
  • 21
    • 0037505736 scopus 로고    scopus 로고
    • P53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells
    • M. Phelps, M. Darley, J.N. Primrose, and J.P. Blaydes p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells Cancer Res 63 10 2003 2616 2623
    • (2003) Cancer Res , vol.63 , Issue.10 , pp. 2616-2623
    • Phelps, M.1    Darley, M.2    Primrose, J.N.3    Blaydes, J.P.4
  • 22
    • 0030477686 scopus 로고    scopus 로고
    • Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
    • D. Alcorta, Y. Xiong, D. Phelps, G. Hannon, D. Beach, and J.C. Barrett Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts Proc Natl Acad Sci USA 93 1996 13742 13747
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13742-13747
    • Alcorta, D.1    Xiong, Y.2    Phelps, D.3    Hannon, G.4    Beach, D.5    Barrett, J.C.6
  • 24
    • 0036499459 scopus 로고    scopus 로고
    • Transcriptional regulation of the human manganese superoxide dismutase gene: The role of specificity protein 1 (Sp1) and activating protein-2 (AP-2)
    • Y. Xu, S. Porntadavity, and D.K. St Clair Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2) Biochem J 362 2002 401 412
    • (2002) Biochem J , vol.362 , pp. 401-412
    • Xu, Y.1    Porntadavity, S.2    St Clair, D.K.3
  • 25
    • 0030608396 scopus 로고    scopus 로고
    • Sp1 and C/EBP-related factor regulate the transcription of human Cu/Zn SOD gene
    • S.J. Seo, H.T. Kim, G. Cho, H.M. Rho, and G. Jung Sp1 and C/EBP-related factor regulate the transcription of human Cu/Zn SOD gene Gene 178 1996 177 185
    • (1996) Gene , vol.178 , pp. 177-185
    • Seo, S.J.1    Kim, H.T.2    Cho, G.3    Rho, H.M.4    Jung, G.5
  • 26
    • 0035421264 scopus 로고    scopus 로고
    • Regulation of the catalase gene promoter by Sp1, CCAAT-recognizing factors, and a WT1/Egr-related factor in hydrogen peroxide-resistant HP100 cells
    • M. Nenoi, S. Ichimura, K. Mita, O. Yukawa, and I.L. Cartwright Regulation of the catalase gene promoter by Sp1, CCAAT-recognizing factors, and a WT1/Egr-related factor in hydrogen peroxide-resistant HP100 cells Cancer Res 61 2001 5885 5894
    • (2001) Cancer Res , vol.61 , pp. 5885-5894
    • Nenoi, M.1    Ichimura, S.2    Mita, K.3    Yukawa, O.4    Cartwright, I.L.5
  • 27
    • 1642298093 scopus 로고    scopus 로고
    • Transcription factor Sp1 mediates p38MAPK-dependent activation of the p21WAF1 gene promoter in vascular smooth muscle cells by pyrrolidine dithiocarbamate
    • S.K. Moon, S.Y. Jung, and C.H. Kim Transcription factor Sp1 mediates p38MAPK-dependent activation of the p21WAF1 gene promoter in vascular smooth muscle cells by pyrrolidine dithiocarbamate Biochem Biophys Res Commun 316 2004 605 611
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 605-611
    • Moon, S.K.1    Jung, S.Y.2    Kim, C.H.3
  • 28
    • 0037088695 scopus 로고    scopus 로고
    • Sp1 transcriptional activity is up-regulated by phosphatase 2A in dividing T lymphocytes
    • I. Lacroix, C. Lipcey, J. Imbert, and B. Kahn-Perles Sp1 transcriptional activity is up-regulated by phosphatase 2A in dividing T lymphocytes J Biol Chem 277 2002 9598 9605
    • (2002) J Biol Chem , vol.277 , pp. 9598-9605
    • Lacroix, I.1    Lipcey, C.2    Imbert, J.3    Kahn-Perles, B.4
  • 29
    • 0028789622 scopus 로고
    • Sp1 is phosphorylated and its DNA binding activity down-regulated upon terminal differentiation of the liver
    • R.W. Leggett, S.A. Armstrong, D. Barry, and C.R. Mueller Sp1 is phosphorylated and its DNA binding activity down-regulated upon terminal differentiation of the liver J Biol Chem 270 43 1995 25879 25884
    • (1995) J Biol Chem , vol.270 , Issue.43 , pp. 25879-25884
    • Leggett, R.W.1    Armstrong, S.A.2    Barry, D.3    Mueller, C.R.4
  • 30
    • 0032859145 scopus 로고    scopus 로고
    • Unequal nuclear Sp1/GC box DNA binding activity distinguishes proliferating from differentiated senescent or apoptotic cells
    • M. Rieber, and M. Strasberg Rieber Unequal nuclear Sp1/GC box DNA binding activity distinguishes proliferating from differentiated senescent or apoptotic cells Int J Cancer 83 1999 359 364
    • (1999) Int J Cancer , vol.83 , pp. 359-364
    • Rieber, M.1    Strasberg Rieber, M.2
  • 31
    • 0033856957 scopus 로고    scopus 로고
    • Investigation of the Alamar Blue [resazurin] fluorescent dye for the assessment of mammalian cell cytotoxicity
    • J. O'Brien, I. Wilson, T. Orton, and F. Pognan Investigation of the Alamar Blue [resazurin] fluorescent dye for the assessment of mammalian cell cytotoxicity Eur J Biochem 267 2000 5421 5426
    • (2000) Eur J Biochem , vol.267 , pp. 5421-5426
    • O'Brien, J.1    Wilson, I.2    Orton, T.3    Pognan, F.4
  • 32
    • 0038732425 scopus 로고    scopus 로고
    • N-Acetyl cysteine enhances UV-mediated caspase 3 activation, fragmentation of E2F-4 and apoptosis in human C8161 melanoma: Inhibition by ectopic bcl-2 expression
    • M. Rieber, and M. Strasberg Rieber N-Acetyl cysteine enhances UV-mediated caspase 3 activation, fragmentation of E2F-4 and apoptosis in human C8161 melanoma: inhibition by ectopic bcl-2 expression Biochem Pharmacol 65 2003 1593 1601
    • (2003) Biochem Pharmacol , vol.65 , pp. 1593-1601
    • Rieber, M.1    Strasberg Rieber, M.2
  • 36
    • 0033214683 scopus 로고    scopus 로고
    • Eosinophil apoptosis is mediated by stimulators of cellular oxidative metabolisms and inhibited by antioxidants: Involvement of a thiol-sensitive redox regulation in eosinophil cell death
    • B. Wedi, J. Straede, B. Wieland, and A. Kapp Eosinophil apoptosis is mediated by stimulators of cellular oxidative metabolisms and inhibited by antioxidants: involvement of a thiol-sensitive redox regulation in eosinophil cell death Blood 94 1999 2365 2373
    • (1999) Blood , vol.94 , pp. 2365-2373
    • Wedi, B.1    Straede, J.2    Wieland, B.3    Kapp, A.4
  • 37
    • 0028097854 scopus 로고
    • Antioxidants modulate induction of programmed endothelial cell death (apoptosis) by endotoxin
    • P.A. Abello, S.A. Fidler, G.B. Bulkley, and T.G. Buchman Antioxidants modulate induction of programmed endothelial cell death (apoptosis) by endotoxin Arch Surg 129 1994 134
    • (1994) Arch Surg , vol.129 , pp. 134
    • Abello, P.A.1    Fidler, S.A.2    Bulkley, G.B.3    Buchman, T.G.4
  • 38
    • 0041823513 scopus 로고    scopus 로고
    • DNA-protein cross-linking via guanine oxidation: Dependence upon protein and photosensitizer
    • K. Kurbanyan, K.L. Nguyen, P. To, E.V. Rivas, A.M. Lueras, and C. Kosinski DNA-protein cross-linking via guanine oxidation: dependence upon protein and photosensitizer Biochemistry 42 2003 10269 10281
    • (2003) Biochemistry , vol.42 , pp. 10269-10281
    • Kurbanyan, K.1    Nguyen, K.L.2    To, P.3    Rivas, E.V.4    Lueras, A.M.5    Kosinski, C.6
  • 39
    • 0036969289 scopus 로고    scopus 로고
    • Effect of mannitol on Helicobacter pylori-induced cyclooxygenase-2 expression in gastric epithelial AGS cells
    • H. Kim, J.Y. Seo, and K.H. Kim Effect of mannitol on Helicobacter pylori-induced cyclooxygenase-2 expression in gastric epithelial AGS cells Pharmacology 66 4 2002 182 189
    • (2002) Pharmacology , vol.66 , Issue.4 , pp. 182-189
    • Kim, H.1    Seo, J.Y.2    Kim, K.H.3
  • 40
    • 21344465482 scopus 로고    scopus 로고
    • Proliferation dynamics in cultured skin fibroblasts from Down syndrome subjects
    • M. Kimura, X. Cao, J. Skurnick, M. Cody, P. Soteropoulos, and A. Aviv Proliferation dynamics in cultured skin fibroblasts from Down syndrome subjects Free Radic Biol Med 39 3 2005 374 380
    • (2005) Free Radic Biol Med , vol.39 , Issue.3 , pp. 374-380
    • Kimura, M.1    Cao, X.2    Skurnick, J.3    Cody, M.4    Soteropoulos, P.5    Aviv, A.6
  • 41
    • 0027405704 scopus 로고
    • Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells
    • S.L. Church, S.W. Grant, L.A. Ridnour, L.W. Oberley, P.E. Swanson, and P.S. Meltzer Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells Proc Natl Acad Sci USA 90 1993 3113 3117
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3113-3117
    • Church, S.L.1    Grant, S.W.2    Ridnour, L.A.3    Oberley, L.W.4    Swanson, P.E.5    Meltzer, P.S.6
  • 42
    • 2642642930 scopus 로고    scopus 로고
    • Chromosome-6 mediated suppression of metastatic ability increases basal expression of UV-inducible superoxide dismutase and induction of p53
    • M. Alvarez, M. Strasberg Rieber, and M. Rieber Chromosome-6 mediated suppression of metastatic ability increases basal expression of UV-inducible superoxide dismutase and induction of p53 Int J Cancer 77 1998 586 591
    • (1998) Int J Cancer , vol.77 , pp. 586-591
    • Alvarez, M.1    Strasberg Rieber, M.2    Rieber, M.3
  • 43
    • 0343049031 scopus 로고    scopus 로고
    • Tumor suppression without differentiation of apoptosis by antisense cyclin D1 gene transfer in K1735 melanoma involves induction of p53, p21WAF1 and superoxide dismutases
    • M. Rieber, and M. Strasberg Rieber Tumor suppression without differentiation of apoptosis by antisense cyclin D1 gene transfer in K1735 melanoma involves induction of p53, p21WAF1 and superoxide dismutases Cell Death Differ 6 1999 1209 1215
    • (1999) Cell Death Differ , vol.6 , pp. 1209-1215
    • Rieber, M.1    Strasberg Rieber, M.2
  • 44
    • 11144356558 scopus 로고    scopus 로고
    • P53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis
    • S.P. Hussain, P. Amstad, P. He, A. Robles, S. Lupold, and I. Kaneko p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis Cancer Res 64 2004 2350 2356
    • (2004) Cancer Res , vol.64 , pp. 2350-2356
    • Hussain, S.P.1    Amstad, P.2    He, P.3    Robles, A.4    Lupold, S.5    Kaneko, I.6
  • 45
    • 11144356558 scopus 로고    scopus 로고
    • P53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis
    • S.P. Hussain, P. Amstad, and P. He p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis Cancer Res 64 2004 2350 2356
    • (2004) Cancer Res , vol.64 , pp. 2350-2356
    • Hussain, S.P.1    Amstad, P.2    He, P.3


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