Inhibition of membrane depolarisation-induced transcriptional activity of cyclic AMP response element binding protein (CREB) by the dual-leucine-zipper- bearing kinase in a pancreatic islet beta cell line

Diabetologia

Volumn 49, Issue 2, 2006, Pages 332-342

  Oetjen, E ^a   Lechleiter, A ^a   Blume, R ^a   Nihalani, D ^b   Holzman, L ^b   Knepel, W ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Beta cells; Calcineurin; Cyclic AMP response element binding protein; Dual leucine zipper bearing kinase; Membrane depolarisation

Indexed keywords

CALCINEURIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; LEUCINE ZIPPER PROTEIN; TRANSCRIPTION FACTOR GAL4;

ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM TRANSPORT; CARCINOMA CELL; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME REGULATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CALCINEURIN; CELL LINE; CELLS, CULTURED; CREB-BINDING PROTEIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENES, REPORTER; GLUCOSE; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MAP KINASE KINASE KINASES; MEMBRANE POTENTIALS; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC;

EID: 31844445992     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-005-0087-1     Document Type: Article

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