Enhanced anti-fibrotic activity of plasmid DNA expressing small interference RNA for TGF-β type II receptor for a mouse model of obstructive nephropathy by cationized gelatin prepared from different amine compounds

Journal of Controlled Release

Volumn 110, Issue 3, 2006, Pages 610-617

  Kushibiki, Toshihiro ^a   Nagata Nakajima, Natsuki ^b   Sugai, Manabu ^b   Shimizu, Akira ^b   Tabata, Yasuhiko ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Cationized gelatin; Gene delivery; Renal interstitial fibrosis; Small interference RNA (siRNA); Transforming growth factor (TGF ) receptor

Indexed keywords

AMINES; GENETIC ENGINEERING; IONIZATION; RNA; VIRUSES;

CATIONIZED GELATIN; GENE DELIVERY; RENAL INTERSTITIAL FIBROSIS; SMALL INTERFERENCE RNA (SIRNA);

DNA;

COLLAGEN; ETHYLENEDIAMINE; GELATIN; PUTRESCINE; SMALL INTERFERING RNA; SPERMIDINE; SPERMINE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG ACTIVITY; GENE OVEREXPRESSION; KIDNEY FIBROSIS; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PLASMID; PRIORITY JOURNAL; URETER OBSTRUCTION;

AMINES; ANIMALS; CATIONS; DISEASE MODELS, ANIMAL; FIBROSIS; GELATIN; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; KIDNEY CORTEX; KIDNEY DISEASES; MALE; MICE; MICE, INBRED C57BL; PLASMIDS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, SMALL INTERFERING;

EID: 31544434264     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.11.007     Document Type: Article

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