A receptor-mediated gene delivery system using streptavidin and biotin-derivatized, pegylated epidermal growth factor

Journal of Controlled Release

Volumn 83, Issue 1, 2002, Pages 109-119

  Lee, Haeshin ^a   Kim, Tae Hyoung ^a   Park, Tae Gwan ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

EGF; Polyethylene glycol (PEG); Receptor mediated gene delivery; Streptavidin biotin

Indexed keywords

BIOTIN DERIVATIVE; EPIDERMAL GROWTH FACTOR DERIVATIVE; LUCIFERASE; MACROGOL DERIVATIVE; NANOPARTICLE; PLASMID DNA; POLYETHYLENEIMINE; PROTEIN DERIVATIVE; STREPTAVIDIN;

ARTICLE; CELL TRANSPORT; CHROMATOGRAPHY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG FORMULATION; DRUG PURIFICATION; DRUG UPTAKE; ENDOCYTOSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMOBILIZATION; MOLECULAR SIZE; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL;

BIOTIN; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; EPIDERMAL GROWTH FACTOR; GENE THERAPY; HUMANS; PLASMIDS; POLYETHYLENEIMINE; RECOMBINANT PROTEINS; STREPTAVIDIN; TUMOR CELLS, CULTURED;

EID: 0037130561     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(02)00166-9     Document Type: Article

References (42)

1. Tripathy S.K., Black H.B., Goldwasser E., Leiden J.M. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat. Med. 2:1996;545-550.
2. Pollard H., Remy J.-S., Loussouarn G., Demolombe S., Behr J.-P., Escande D. Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J. Biol. Chem. 273:1998;7507-7511.
3. Chonn A., Cullis P.R. Recent advances in liposome technologies and their application for systemic gene delivery. Adv. Drug Deliv. Rev. 30:1998;73-83.
4. Parente R.A., Nir S., Szoka F.C. Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA. Biochemistry. 29:1990;8720-8728.
5. Wagner E. Application of membrane-active peptides for nonviral gene delivery. Adv. Drug Deliv. Rev. 38:1999;279-289.
6. De Smedt S.C., Demeester J., Hennink W.E. Cationic polymer based gene delivery systems. Pharm. Res. 17:2000;113-126.
7. Templeton N.S., Lasic D.D. Gene Therapy: Therapeutic Mechanisms and Strategies. 2000;131-139 Marcel Dekker, New York.
8. Godbey W.T., Kenneth K.W., Mikos A.G. Poly(ethylenimine) and its role in gene delivery. J. Control. Release. 60:1999;149-160.
9. Zauner W., Ogris M., Wagner E. Polylysine-based transfection systems utilizing receptor-mediated delivery. Adv. Drug. Deliv. Rev. 30:1998;97-113.
10. Haensler J., Szoka F.C. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug. Chem. 4:1993;372-379.
11. Cherng J.Y., Wetering P.V.D., Talsma H., Crommelin D.J.A., Hennink W.E. Effect of size and serum proteins on transfection efficiency of poly(2-dimethyamino)-ethyl methacrylate)-based gene delivery. Pharm. Res. 13:1996;1038-1042.
12. Lim D.W., Yeom Y.I., Park T.G. Poly(DMAEMA-NVP)-b-PEG-galactose as gene delivery vector for hepatocytes. Bioconjug. Chem. 11:2000;688-695.
13. Wolfert M.A., Schacht E.H., Toncheva V., Ulbrich K., Nazarova O., Seymour L.W. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum. Gene Ther. 7:1996;2123-2133.
14. Katayose S., Kataoka K. Water-soluble polyion complex associates of DNA and poly(ethylene glycol) poly(L-lysine) block co-polymer. Bioconjug. Chem. 8:1997;702-707.
15. Lee H., Jeong J.H., Park T.G. A new gene delivery formulation of polyethylenimine-DNA complexes coated with PEG conjugated fusogenic peptide. J. Control. Release. 76:2001;183-192.
16. Crystal R.G. Transfer of genes to humans: early lessons and obstacles to success. Science. 270:1995;404-410.
17. Templeton N.S., Lasic D.D. Gene Therapy: Therapeutic Mechanisms and Strategies. 2000;141-164 Marcel Dekker, New York.
18. Sosnowski B.A., Gonzalez A.M., Chandler L.A., Buechler Y.J., Pierce G.F., Baird A. Targeting DNA to cells with basic fibroblast growth factor (FGF2). J. Biol. Chem. 271:1996;33647-33653.
19. Hart S.L., Harbottle R.P., Copper R., Miller A., Williamson R., Coutelle C. Gene delivery and expression mediated by an integrin-binding peptide. Gene Ther. 2:1995;552-554.
20. Buschle M., Cotton M., Kirlappos H., Mechtler K., Schaffner G., Zaunter W., Birnstiel M.L., Wagner E. Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex. Hum. Gene Ther. 6:1995;753-761.
21. Merwin J.R., Carmichael E.P., Noell G.S., DeRome M.E., Thomas W.L., Robert N., Spitalny G., Chiou H.C. CD5-mediated specific delivery of DNA to T lymphocytes: compartmentalization augmented by adenovirus. J. Immunol. Methods. 186:1995;257-266.
22. Wagner E., Zenke M., Cotton M., Beug H., Birnstiel M.L. Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc. Natl. Acad. Sci. USA. 87:1990;3410-3414.
23. Haensler J., Szoka F.C. Synthesis and characterization of a trigalactosylated bisacridine compound to target DNA to hepatocytes. Bioconjug. Chem. 21:1993;871-878.
24. Fantl W.J., Johnson D.E., Williams L.T. Signaling by receptor tyrosine kinase. Annu. Rev. Biochem. 62:1993;453-481.
25. Allrich A., Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell. 61:1990;203-212.
26. Carpenter G., Cohen S. Epidermal growth factor. Annu. Rev. Biochem. 48:1979;193-216.
27. Gill G.N., Lazar C.S. Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells. Nature. 293:1981;305-307.
28. Barnes D.W. Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture. J. Cell Biol. 93:1982;1-4.
29. Xu B., Wiehle S., Roth J.A., Cristiano R.J. The contribution of poly-L-lysine, epidermal growth factor and streptavidin to EGF/PLL/DNA polyplex formation. Gene Ther. 5:1998;1235-1243.
30. Cristiano R.J., Roth J.A. Epidermal growth factor mediated DNA delivery into lung cancer cells via the epidermal growth factor receptor. Cancer Gene Ther. 3:1996;4-10.
31. Fisher K.D., Ulbrich K., Subr V., Ward C.M., Mautner V., Blakey D., Seymour L.W. A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression. Gene Ther. 7:2000;1337-1343.
32. Chen J., Gamou S., Takayanagi A., Shimizu N. A novel gene delivery system using EGF receptor-mediated endocytosis. FEBS Lett. 338:1994;167-169.
33. Krupp M.N., Connolly D.T., Lane M.D. Synthesis, turnover and down-regulation of epidermal growth factor receptors in human A431 epidermal carcinoma cells and skin fibroblasts. J. Biol. Chem. 257:1982;11489-11496.
34. Weber P.C., Ohlendorf D.H., Wendoloski J.J., Salemme F.R. Structural origins of high-affinity biotin binding to streptavidin. Science. 243:1989;85-88.
35. Green N.M. Avidin. Adv. Protein Chem. 29:1975;85-133.
36. Green N.M. Spectrophotometric determination of avidin and biotin. Methods Enzymol. 18A:1970;418-430.
37. Chiou H.C., Tangoo M.V., Levine S.M., Robertson D., Kormis K., Wu C.H., Wu G.Y. Enhanced resistance to nuclease degradation of nucleic acids complexed to asialoglycoprotein-polylysine carriers. Nucleic Acids Res. 22:1994;5439-5446.
38. Katayose S., Kataoka K. Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(L-lysine) block copolymer. J. Pharm. Sci. 87:1998;160-163.
39. Cohen S., Carpenter G. Human epidermal growth factor: isolation and chemistry and biological properties. Proc. Natl. Acad. Sci. USA. 72:1975;1317-1321.
40. Argarana C.E., Kuntz I.D., Birken S., Axel R., Cantor C.R. Molecular cloning and nucleotide sequence of the streptavidin gene. Nucleic Acids Res. 14:1986;1871-1882.
41. Zauner W., Ogris M., Wagner E. Polylysine-based transfection systems utilizing receptor-mediated delivery. Adv. Drug. Deliv. Rev. 30:1998;97-113.
42. Hognason T., Chatterjee S., Vartanian T., Ratan R.R., Erneswein K.M., Habib A.A. Epidermal growth factor receptor induced apoptosis: potentiation by inhibition of Ras signaling. FEBS Lett. 491:2001;9-15.