Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes

Biochemistry

Volumn 45, Issue 2, 2006, Pages 533-542

  Jiang, Yongying ^a   He, Xiang ^a   Ortiz De Montellano, Paul R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CATALYSIS; CHEMICAL ANALYSIS; ENZYMES; HYDROCARBONS; HYDROXYLATION; ISOMERS;

4-HYDROXYLATED ISOMERS; CATALYTIC OXIDATION; HUMAN CYTOCHROME P450 ENZYMES; SOLVENT DEUTERIUM ISOTOPE EFFECT;

OXIDATION;

2 HYDROXY ALPHA THUJONE; 2 HYDROXY BETA THUJONE; 4 HYDROXY ALPHA THUJONE; 4 HYDROXY BETA THUJONE; 4,10 DEHYDROTHUJONE; 5 HYDROXY 5 ISOPROPYL 2 METHYL 2 CYCLOHEXEN 1 ONE; 7 HYDROXY ALPHA THUJONE; 7 HYDROXY BETA THUJONE; 7,8 DEHYDRO ALPHA THUJONE; 7,8 DEHYDRO BETA THUJONE; ABSINTHOL; BETA THUYONE; CARVACROL; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; HYDROCARBON; HYDROPEROXIDE; IRON BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATION TRANSPORT; CHEMICAL REACTION KINETICS; ENZYME ANALYSIS; FATTY ACID DESATURATION; HUMAN; HUMAN TISSUE; HYDROXYLATION; ISOMERISM; OXIDATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RING OPENING; STEREOCHEMISTRY; SUBSTITUTION REACTION;

ALANINE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; CAMPHOR 5-MONOOXYGENASE; CATALYSIS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; DEUTERIUM OXIDE; FREE RADICALS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROXYLATION; ISOMERISM; LEUCINE; MONOTERPENES; OXIDATION-REDUCTION;

BACTERIA (MICROORGANISMS);

EID: 30744438083     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051840z     Document Type: Article

References (43)

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