DNA polymerization by the reverse transcriptase of the human L1 retrotransposon on its own template in vitro

FEBS Letters

Volumn 580, Issue 2, 2006, Pages 661-668

  Piskareva, Olga ^a   Schmatchenko, Vadim ^a  

^a SKRYABIN INSTITUTE OF BIOCHEMISTRY AND PHYSIOLOGY OF MICROORGANISMS   (Russian Federation)

Author keywords

LINE 1; Non LTR retrotransposons; Pausing; Processivity; Retroviruses; Reverse transcriptase

Indexed keywords

COMPLEMENTARY DNA; RNA DIRECTED DNA POLYMERASE;

ARTICLE; DNA SYNTHESIS; IN VITRO STUDY; LONG INTERSPERSED REPEAT; POLYMERIZATION; PRIORITY JOURNAL; RETROPOSON; REVERSE TRANSCRIPTION;

ANIMALS; BASE SEQUENCE; CAPSID PROTEINS; DNA; DNA REPLICATION; GLYCOPROTEINS; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MOLECULAR SEQUENCE DATA; MOLONEY MURINE LEUKEMIA VIRUS; NUCLEIC ACID CONFORMATION; RETROELEMENTS; RIBONUCLEASE H, CALF THYMUS; RNA-DIRECTED DNA POLYMERASE;

INSECTA; MOLONEY MURINE LEUKEMIA VIRUS;

EID: 30644465699     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.12.077     Document Type: Article

References (39)

1. E.M. Ostertag, and H.H. Kazazian Jr. Biology of mammalian L1 retrotransposons Annu. Rev. Genet. 35 2001 501 538
2. H. Hohjoh, and M.F. Singer Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposon EMBO J. 16 1997 6034 6043
3. Q. Feng, J.V. Moran, H.H. Kazazian, and J.D. Boeke Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition Cell 87 1996 905 916
4. S.L. Mathias, A.F. Scott, H.H. Kazazian Jr., J.D. Boeke, and A. Gabriel Reverse transcriptase encoded by a human transposable element Science 254 1991 1808 1810
5. W. Wei, N. Gilbert, S.L. Ooi, J.F. Lawler, E.M. Ostertag, H.H. Kazazian, J.D. Boeke, and J.V. Moran Human L1 retrotransposition: cis preference versus trans complementation Mol. Cell. Biol. 21 2001 1429 1439
6. E.S. Lander, L.M. Linton, B. Birren, C. Nusbaum, M.C. Zody, J. Baldwin, K. Devon, K. Dewar, and M. Doyle Initial sequencing and analysis of the human genome Nature 409 2001 860 921
7. J.V. Moran, S.E. Holmes, T.P. Naas, R.J. DeBerardinis, J.D. Boeke, and H.H. Kazazian Jr. High frequency retrotransposition in cultured mammalian cells Cell 87 1996 917 927
8. G.J. Cost, Q. Feng, A. Jacquier, and J.D. Boeke Human L1 element target-primed reverse transcription in vitro EMBO J. 21 2002 5899 5910
9. D.D. Luan, M.H. Korman, J.L. Jakubczak, and T.H. Eickbush Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition Cell 72 1993 595 605
10. A. Bibillo, and T.H. Eickbush High processivity of the reverse transcriptase from a non-long terminal repeat retrotransposon J. Biol. Chem. 277 2002 34836 34845
11. A. Bibillo, and T.H. Eickbush The reverse transcriptase of the R2 non-LTR retrotransposon: continuous synthesis of cDNA on non-continuous RNA templates J. Mol. Biol. 316 2002 459 473
12. O.A. Piskareva, S.V. Denmukhametova, and V.V. Schmatchenko Functional reverse transcriptase encoded by the human LINE-1 from baculovirus-infected insect cells Protein Expr. Purif. 28 2003 125 130
13. B.A. Dombroski, S.L. Mathias, E. Nanthakumar, A.F. Scott, and H.H. Kazazian Jr. Isolation of an active human transposable element Science 254 1991 1805 1808
14. J.J. DeStefano, R.G. Buiser, L.M. Mallaber, T.W. Myers, R.A. Bambara, and P.J. Fay Polymerization and RNase H activities of reverse transcriptases from avian myeloblastosis, human immunodeficiency and Moloney murine leukemia viruses are functionally uncoupled J. Biol. Chem. 266 1991 7423 7431
15. O. Avidan, M.E. Meer, I. Oz, and A. Hizi The processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus Eur. J. Biochem. 269 2002 859 867
16. G.J. Klarmann, C.A. Schauber, and B.D. Preston Template-directed pausing of DNA synthesis by HIV-1 reverse transcriptase during polymerization of HIV-1 sequences in vitro J. Biol. Chem. 268 1993 9793 9802
17. K.J. Williams, L.A. Loeb, and M. Fry Synthesis of DNA by human immunodeficiency virus reverse transcriptase is preferentially blocked at template oligo (deoxyadenosine) tracts J. Biol. Chem. 265 1990 18682 18689
18. G.P. Harrison, M.S. Mayo, E. Hunter, and A.M.L. Lever Pausing of reverse transcriptase on retroviral RNA templates is influenced by secondary structures both 5′ and 3′ of the catalytic site Nucleic Acids Res. 26 1998 3433 3442
19. M. Zuker Mfold web server for nucleic acid folding and hybridization prediction Nucleic Acids Res. 31 2003 3406 3415
20. H.S. Malik, W.D. Burke, and T.H. Eickbush The age and evolution of non-LTR retrotransposable elements Mol. Biol. Evol. 16 1999 793 805
21. J.M. Whitcomb, and S.H. Hughes Retroviral reverse transcription and integration: progress and problems Annu. Rev. Cell Biol. 8 1992 275 306
22. S.P. Goff Genetic control of retrovirus susceptibility in mammalian cells Annu. Rev. Genet. 38 2004 61 85
23. L.A. Kohlstaedt, J. Wang, J.M. Friedman, P.A. Rice, and T.A. Steitz Crystal structure at 3.5 Å of HIV-1 reverse transcriptase complexed with an inhibitor Science 256 1992 1783 1790
24. A. Jacobo-Molina, J. Ding, R.G. Nanni, A.D.J. Clark, X. Lu, C. Tantillo, R.L. Williams, G. Kamer, A.L. Ferris, P. Clark, A. Hizi, S.H. Hughes, and E. Arnold Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA Proc. Natl Acad. Sci. USA 90 1993 6320 6324
25. Y. Xiong, and T.H. Eickbush Origin and evolution of retroelements based on their reverse transcriptase sequences EMBO J. 9 1990 3351 3362
26. T.M. Nakamura, G.B. Morin, K.B. Chapman, S.L. Weinrich, W.H. Andrews, J. Lingner, C.B. Harley, and T.R. Cech Telomerase catalytic subunit homologs from fission yeast and human Science 277 1997 955 959
27. Y. Kew, L.R. Olsen, A.J. Japour, and V.R. Prasad Insertions into the β3-β4 hairpin loop of HIV-1 reverse transcriptase reveal a role for fingers subdomain in processive polymerization J. Biol. Chem. 273 1998 7529 7537
28. D. Jeruzalmi, M. O'Donnell, and J. Kuriyan Clamp loaders and sliding clamps Curr. Opin. Struct. Biol. 12 2002 217 224
29. T. Fanning, and M. Singer The line-1 DNA sequences in 4 mammalian orders predict proteins that conserve homologies to retrovirus proteins Nucleic Acids Res. 15 1987 2251 2260
30. J.J. Champoux Roles of ribonuclease H in reverse transcription A.M. Skalka S.P. Goff Reverse Transcriptase 1993 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 103 117
31. A.H. Farley, E.T. Luning Prak, and H.H. Kazazian Jr. More active human L1 retrotransposons produce longer insertions Nucleic Acids Res. 32 2004 502 510
32. R. Howell, and K. Usdin The ability to form intrastrand tetraplexes is an evolutionarily conserved feature of the 3′ end of L1 retrotransposons Mol. Biol. Evol. 14 1997 144 155
33. K. Usdin, and A.V. Furano The structure of the guanine-rich polypurine:polypyrimidinesequence at the right end of the rat L1 (LINE) element J. Biol. Chem. 264 1989 15681 15687
34. S.L. Martin, and F.D. Bushman Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE-1 retrotransposon Mol. Cell. Biol. 21 2001 467 475
35. S. Boissinot, P. Chevret, and A.V. Furano L1 (LINE-1) retrotransposon evolution and amplification in recent human history Mol. Biol. Evol. 17 2000 915 928
36. A. Pavlicek, J. Paces, R. Zika, and J. Hejnar Length distribution of long interspersed nuclear elements (LINEs) and processed pseudogenes of human endogenous retroviruses: implications for retrotransposition and processed pseudogene detection Gene 300 2002 189 194
37. J.S. Myers, B.J. Vincent, H. Udall, W.S. Watkins, T.A. Morrish, G.E. Kilroy, G.D. Swergold, J. Henke, L. Henke, J.V. Moran, L.B. Jorde, and M.A. Batzer A comprehensive analysis of recently integrated human Ta L1 elements Am. J. Hum. Genet. 71 2002 312 326
38. A.-H. Salem, J.S. Myers, A.C. Otieno, W.S. Watkins, L.B. Jorde, and M.A. Batzer LINE-1 pre-Ta elements in the human genome J. Mol. Biol. 326 2003 1127 1146
39. S.M. Lutz, B.J. Vincent, H.H. Kazazian, M.A. Batzer, and J.V. Moran Allelic heterogeneity in LINE-1 retrotransposon activity Am. J. Hum. Genet. 73 2003 1431 1437