The BTB domain of the nuclear matrix protein NRP/B is required for neurite outgrowth

Journal of Cell Science

Volumn 118, Issue 23, 2005, Pages 5537-5548

  Kim, Tae Aug ^a   Jiang, Shuxian ^a   Seng, Seyha ^a   Cha, Kiweon ^a   Avraham, Hava Karsenty ^a   Avraham, Shalom ^a  

^a HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

BTB POZ domain; Neurite outgrowth; Neuronal differentiation; NRP B; Nuclear matrix

Indexed keywords

BRAIN NUCLEAR MATRIX RESTRICTED PROTEIN; GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; NERVE GROWTH FACTOR; NUCLEAR MATRIX PROTEIN; PROTEIN P110; SERINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL POPULATION; CONTROLLED STUDY; DIMERIZATION; DOWNSTREAM PROCESSING; HUMAN; HUMAN CELL; MOLECULAR MODEL; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; RAT; STATISTICAL SIGNIFICANCE; WILD TYPE;

ANIMALS; ANTIBODIES; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; MICROFILAMENT PROTEINS; MUTATION; NEURITES; NEURONS; NEUROPEPTIDES; NUCLEAR PROTEINS; PC12 CELLS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RATS; RNA, SMALL INTERFERING;

ANIMALIA;

EID: 30544446701     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02643     Document Type: Article

References (47)

1. Bardwell, V. J. and Treisman, R. (1994). The POZ domain: a conserved protein-protein interaction motif. Genes Dev. 8, 1664-1677.
2. Berezney, R. (1991). Visualizing DNA replication sites in the cell nucleus. Semin. Cell Biol. 2, 103-115.
3. Bomont, P., Cavalier, L., Blondeau, F., Ben Hamida, C., Belal, S., Tazir, M., Demir, E., Topaloglu, H., Korinthenberg, R., Tuysuz, B. et al. (2000). The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy. Nat. Genet. 26, 370-374.
4. Bruel, C., Cha, K. W., Niu, L., Reeves, P. J. and Khorana, H. G. (2000). Rhodopsin kinase: Two monoclonal antibodies binding near the carboxy-terminus cause time dependent inactivation. Proc. Natl. Acad. Sci. USA 97, 3010-3015.
5. Carr, C. M., Chaudhury, C. and Kim, P. S. (1997). Influenza hemagglutinin is spring-loaded by a metastable native conformation. Proc. Natl. Acad. Sci. USA 94, 14306-14313.
6. Cha, K. W., Reeves, P. J. and Khorana, H. G. (2000). Structure and function in Rhodopsin. Rhodopsin: Destabilization of Rhodopsin by the binding of an antibody at the amino terminal segment provides support for involvement of the latter in an intrediscal tertiary structure. Proc. Natl. Acad. Sci. USA 97, 3016-3021.
7. Chen, W., Zollman, S., Couderc, J. L. and Laski, F. A. (1995). The BTB domain of bric a brac mediates dimerization in vitro. Mol. Cell. Biol. 15, 3424-3429.
8. Collins, T., Stone, J. R. and Williams, A. J. (2001). All in the family: the BTB/POZ, KRAB, and SCAN domains. Mol. Cell. Biol. 21, 3609-3615.
9. Dhordain, P., Albagli, O., Ansieau, S., Koken, M. H., Deweindt, C., Quief, S., Lantoine, D., Leutz, A., Kerckaert, J. P. and Leprince, D. (1995). The BTB/POZ domain targets the LAZ3/BCL6 oncoprotein to nuclear dots and mediates homomerisation in vivo. Oncogene 11, 2689-2697.
10. Dhordain, P., Albagli O., Lin, R. J., Ansieau, S., Quief, S. Leutz, A., Kerckaert, J. P., Evans, R. M. and Leprince, D. (1997). Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein. Proc. Natl. Acad. Sci. USA 94, 10762-10767.
11. Dhordain, P., Lin, R. J., Quief, S., Lantoine, D., Kerckaert, J. P., Evans, R. M. and Albagli, O. (1998). The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression. Nucleic Acids Res. 26, 4645-4651.
12. Dong, S., Zhu, J., Reid, A., Strutt, P., Guidez, F., Zhong, H. J. Wang, Z. Y., Licht, J., Waxman, S. and Chomienne, C. (1996). Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein. Proc. Natl. Acad. Sci. USA 93, 3624-3629.
13. Dworetzky, S. I., Fey, E. G., Penman, S., Lian, J. B., Stein, J. L. and Stein, G. S. (1990). Progressive changes in the protein composition of the nuclear matrix during rat osteoblast differentiation. Proc. Natl. Acad. Sci. USA 87, 4605-4609.
14. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K. and Tischi, T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
15. Fey, E. G. and Penman, S. (1988). Nuclear matrix proteins reflect cell type of origin in cultured human cells. Proc. Natl. Acad. Sci. USA 85, 121-125.
16. Geisert, E. E., Jr, Johnson, H. G. and Binder, L. I. (1990). Expression of microtubule-associated protein 2 by reactive astrocytes. Proc. Natl. Acad. Sci. USA 87, 3967-3971.
17. Gibson, T. J., Thompson, J. D., Blocker, A. and Kouzarides, T. (1994). Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107. Nucleic Acids Res. 22, 946-952.
18. Godt, D., Couderc, J. L., Cramton, S. E. and Laski, F. A. (1993). Pattern formation in the limbs of Drosophila: bric a brac is expressed in both a gradient and a wave-like pattern and is required for specification and proper segmentation of the tarsus. Development 119, 799-812.
19. Gu, W., Schneider, J. W., Condorelli, G., Kaushal, S., Mahdavi, V. and Nadal-Ginard, B. (1993). Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72, 309-324.
20. He, D., Zeng, C. and Brinkley, B. R. (1995). Nuclear matrix proteins as structural and functional components of the mitotic apparatus. Int. Rev. Cyto. 1, 1-74.
21. Hernandez, M. C., Andres-Barquin, P. J., Martinez, S., Bulfone, A., Rubenstein, J. L. and Israel, M. A. (1997). ENC-1: a novel mammalian kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein. J. Neurosci. 17, 3038-3051.
22. Kim, T. A., Lim, J., Ota, S., Raja, S., Rogers, R., Rivnay, B., Avraham, H. and Avraham, S. (1998). NRP/B, a novel nuclear matrix protein, associates with p110(RB) and is involved in neuronal differentiation. J. Cell Biol. 141, 553-566.
23. Kim, T. A., Ota, S., Jiang, S., Pasztor, L. M., White, R. A. and Avraham, S. (2000). Genomic organization, chromosomal localization and regulation of expression of the neuronal nuclear matrix protein NRP/B in human brain tumors. Gene 255, 105-116.
24. Kranenburg, O., Scharnhorst, V., Van der Eb, A. and Zantema, A. (1995). Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells. J. Cell Biol. 131, 227-234.
25. Lee, E. Y., Hu, N., Yuan, S. S., Cox, L. A., Bradley, A., Lee, W. H. and Herrup, K. (1994). Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 8, 2008-2021.
26. Li, X., Peng, H., Schultz, D. C., Lopez-Guisa, J. M., Rauscher III, F. J. and Marmorstein, R. (1999). Structure-function studies of the BTB/POZ transcriptional repression domain from the promyelocytic leukemia zinc finger oncoprotein. Cancer Res. 59, 5275-5282.
27. Liang, X. Q., Avraham, H. K., Jiang, S. and Avraham, S. (2004). Genetic alterations of the NRP/B gene are associated with human brain tumors. Oncogene 23, 5890-5900.
28. Lin, R. J., Nagy, L., Inoue, S., Shao, W., Miller, Jr, W. H. and Evans, R. M. (1998). Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature 391, 811-814.
29. Mancini, M. A., Shan, B., Nickerson, J. A., Penman, S. and Lee, W. H. (1994). The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. Proc. Natl. Acad. Sci. USA 91, 418-422.
30. McPherson, J. D., Marra, M., Hillier, L., Waterston, R. H., Chinwalla, A., Wallis, J., Sekhon, M., Wylie, K., Mardis, E. R., Wilson, R. K. et al. (2001). A physical map of the human genome. Nature 409, 934-941.
31. Melnick, A. M., Westendorf, J. J., Polinger, A., Carlile, G. W., Arai, S., Ball, H. J., Lutterbach, B., Hiebert, S. W. and Licht, J. D. (2000a). The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein. Mol. Cell. Biol. 20, 2075-2086.
32. Melnick, A., Ahmad, K. F., Arai, S., Polinger, A., Ball, H., Borden, K. L., Carlile, G. W., Prive, G. G. and Licht, J. D. (2000b). In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions. Mol. Cell. Biol. 20, 6550-6567.
33. Melnick, A., Carlile, G., Ahmad, K. F., Kiang, C. L., Corcoran, C., Bardwell, V., Prive, G. G. and Licht, J. D. (2002). Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors. Mol. Cell. Biol. 22, 1804-1818.
34. Penman, S. (1995). Rethinking cell structure. Proc. Natl. Acad. Sci. USA 92, 5251-5257.
35. Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W. and Vogelstein, B. (1997). A model for p53-induced apoptosis. Nature 389, 300-305.
36. Reid, A., Gould, A., Brand, N., Cook, M., Strutt, P., Li, J., Licht, J., Waxman, S., Krumlauf, R. and Zelent, A. (1995). Leukemia translocation gene, PLZF, is expressed with a speckled nuclear pattern in early hematopoietic progenitors. Blood 86, 4544-4552.
37. Robinson, D. N. and Cooley, L. (1997). Drosophila kelch is an oligomeric ring canal actin organizer. J. Cell Biol. 138, 799-810.
38. Slack, R. S., El-Bizri, H., Wong, J., Belliveau, D. J. and Miller, F. D. (1998). A critical temporal requirement for the retinoblastoma protein family during neuronal determination. J. Cell Biol. 140, 1497-1509.
39. Soltysik-Espanola, M., Rogers, R. A., Jiang, S., Kim, T. A., Gaedigk, R., White, R. A., Avraham, H. and Avraham, S. (1999). Characterization of Mayven, a novel actin-binding protein predominantly expressed in brain. Mol. Biol. Cell 10, 2361-2375.
40. Stein, G. S. and Berezney, R. (1996). Nuclear structure and function. J. Cell Biochem. 62, 147-148.
41. Sugiura, K., Muro, Y., Nagai, Y., Kamimoto, T., Wakabayashi, T., Ohashi, M. and Hagiwara, M. (1997). Expression cloning and intracellular localization of a human ZF5 homologue. Biochim. Biophys. Acta 1352, 23-26.
42. Varkey, J. P., Muhlrad, P. J., Minniti, A. N., Do, B. and Ward, S. (1995). The Caenorhabditis elegans spe-26 gene is necessary to form spermatids and encodes a protein similar to the actin-associated proteins kelch and scruin. Genes Dev. 9, 1074-1086.
43. Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A. et al. (2001). The sequence of the human genome. Science 291, 1304-1351.
44. Wong, C. W. and Privalsky, M. L. (1998). Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6. J. Biol. Chem. 273, 27695-27702.
45. Yeyati, P. L., Shaknovich, R., Boterashvili, S., Li, J., Ball, H. J., Waxman, S., Nason-Burchenal, K., Dmitrovsky, E., Zelent, A. and Licht, J. D. (1999). Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A. Oncogene 18, 925-934.
46. Zhao, L., Gregoire, F. and Sul, H. S. (2000). Transient induction of ENC-1, a kelch-related actin-binding protein, is required for adipocyte differentiation. J. Biol. Chem. 275, 16845-16850.
47. Zollman, S., Godt, D., Prive, G. G., Couderc, J. L. and Laski, F. A. (1994). The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. Proc. Natl. Acad. Sci. USA 91, 10717-10721.