A critical temporal requirement for the retinoblastoma protein family during neuronal determination

Journal of Cell Biology

Volumn 140, Issue 6, 1998, Pages 1497-1509

  Slack, Ruth S ^a,b   El Bizri, Hiba ^a   Wong, Josée ^a   Belliveau, Daniel J ^a,c   Miller, Freda D ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; BETA GALACTOSIDASE; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; MITOSIS; MOUSE; NEOCORTEX; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; TUMOR SUPPRESSOR GENE;

ANIMALS; BIOTIN; CELL DIFFERENTIATION; CELL SURVIVAL; CEREBRAL CORTEX; DEOXYURACIL NUCLEOTIDES; DNA FRAGMENTATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LAC OPERON; MICE; MICE, TRANSGENIC; MITOSIS; NEURONS; RETINOBLASTOMA PROTEIN; SPINAL CORD; STAINING AND LABELING; STEM CELLS; TIME FACTORS; TUBULIN;

EID: 0032559849     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.140.6.1497     Document Type: Article

References (41)

1. Bamji, S.X., and F.D. Miller. 1996. Comparison of the expression of a Tα1: nlacZ transgene and Tα1 α-tubulin mRNA in the mature central nervous system. J. Comp. Neurol. 374:52-69.
2. Blake, M.C., and J.C. Azizkhan. 1989. Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo. Mol. Cell. Biol. 11:4994-5002.
3. Brewer, G.J., J.R. Torricelli, E.K. Evege, and P.J. Price. 1993. Optimized survival of hippocampal neurons in B27-supplemented neurobasal, a new serum-free medium combination. J. Neurosci. Res. 35:567-576.
4. Clarke, A.R., E.R. Maandag, M. Van Roon, N.M.T. Van der Lugt, M. Van der Valk, M.I. Hooper, A. Berns, and H. Te Riele. 1992. Requirement for a functional Rb1 gene in murine development. Nature. 359:328-330.
5. Cobrinik, D., S.F. Dowdy, P.W. Hinds, S. Mittnacht, and R.A. Weinberg. 1992. The retinoblastoma protein and the regulation of cell cycling. Trends Biochem. Sci. 17:312-315.
6. Dalton, S. 1992. Cell cycle regulation of the human cdc 2 gene. EMBO (Eur. Mol. Biol. Organ.) J. 11:1797-1807.
7. Farnham, P.J., J.E. Slansky, and R. Kollmar. 1993. The role of E2F in the mammalian cell cycle. Biochim. Biophys. Acta. 1155:125-131.
8. Ghosh, A., and M.E. Greenberg. 1995. Distinct roles for bFGF and NT3 in the regulation of cortical neurogenesis. Neuron. 15:89-103.
9. Gloster, A., W. Wu, A. Speelman, S. Weiss, C. Causing, C. Pozniak, B. Reynolds, E. Chang, J.G. Toma, and F.D. Miller. 1994. The Tα1 αtubulin promoter specifies gene expression as a function of neuronal growth and regeneration in transgenic mice. J. Neurosci. 14:7319-7330.
10. Hamel, P.A., B.L. Gallie, and R.A. Phillips. 1992. The retinoblastoma protein and cell cycle regulation. Trends Genet. 8:180-185.
11. Hannon, G.J., D. Demetrick, and D. Beach. 1993. Isolation of the Rb-related p130 through its interaction with Cdk2 and cyclins. Genes Dev. 7:2378-2381.
12. Heintz, N. 1993. Cell death and the cell cycle: a relationship between transformation and neurodegeneration. Trends Neurosci. 18:157-159.
13. Hsiao, K.M., S.L. McMahon, and P.J. Garnham. 1994. Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev. 8:1526-1537.
14. Jacks, T., A. Fazeli, E.M. Schmitt, R.T. Bronson, M.A. Goodell, and R.A. Weinberg. 1992. Effects of an Rb mutation in the mouse. Nature. 359:295-300.
15. Jelsma, T.N., J.A. Howe, C.M. Evelegh, N.F. Cunniff, M.H. Skiadopoulos, M.R. Floroff, J.E. Denman, and S.T. Bayley. 1988. Use of deletion and point mutants spanning the coding region of the adenovirus 5 E1A gene to define a domain that is essential for transcriptional activation. Virology. 163:494-502.
16. Johnson, D.G., K. Ohtani, and J.R. Nevins. 1994. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev. 8:1514-1525.
17. Lam, E.W.F., and R.J. Watson. 1993. An E2F binding site mediates cell cycle regulated repression of mouse Bmyb transcription. EMBO (Eur. Mol. Biol. Organ.) J. 12:2705-2713.
18. Lee, E.H.P., C.Y. Chang, N. Hu, Y.C.J. Wang, C.C. Lai, K. Herrup, W. Lee, and A. Bradley. 1992. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature. 359:288-294.
19. Lee, E.H.P., N. Hu, S.S.F. Yuan, L.A. Cox, A. Bradley, W. Lee, and K. Herrup. 1994. Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 8:2008-2021.
20. Li, Y., C. Graham, S. Lacy, A.M. Duncan, and P. Whyte. 1993. The adenovirus E1Aassociated 130 kd protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclin A and E. Genes Dev. 7:2366-2377.
21. MacLeod, K.F., Y. Hu, and T. Jacks. 1996. Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO (Eur. Mol. Biol. Organ.) J. 15:6178-6188.
22. Mayol, X., X. Grana, A. Baldi, N. Sang, Q. Hu, and A. Giordano. 1993. Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene. 8:2561-2566.
23. McConnell, S.K., and C.E. Kaznowski. 1991. Cell cycle dependence of laminar determination in developing neocortex. Science. 254:282-285.
24. McLoon, S.C., and R.B. Barnes. 1989. Early differentiation of retinal ganglion cells: an axonal protein expressed by premigratory and migrating retinal ganglion cells. J. Neurosci. 9:1424-1432.
25. Miller, F.D., C.C.G. Naus, M. Durand, F.E. Bloom, and R.J. Milner. 1987. Isotypes of α-tubulin are differentially regulated during neuronal maturation. J. Cell Biol. 105:3065-3073.
26. Miller, F.D., D. Rogers, S.X. Bamji, R.S. Slack, and A. Gloster. 1996. Analysis and manipulation of neuronal gene expression using the Tα1 α-tubulin promoter. Semin. Neurosci. 8:117-124.
27. Miller, F.D., W. Tetzlaff, M.A. Bisby, J.W. Fawcett, and R.J. Milner. 1989. Rapid induction of the major embryonic α-tubulin mRNA. Tα1, during nerve regeneration in adult rats. J. Neurosci. 9:1452-1463.
28. Pearson, B.E., H.P. Nasheuer, and T.S.F. Wang. 1991. Human DNA polymerase alpha gene: sequences controlling expression of cycling and serum-stimulated cells. Mol. Cell. Biol. 11:2081-2095.
29. Picksley, S.M., and D.P. Lane. 1994. p53 and Rb: Their cellular roles. Curr. Opin. Cell Biol. 6:853-858.
30. Schneider, J.W., W. Gu, L. Zhu, V. Mahdavi, and B. Nadal-Ginard. 1994. Reversal of terminal differentiation mediated by p107 in Rb-/-muscle cells. Science. 264:1467-1471.
31. Sherr, C.J. 1993. Mammalian G1 cyclins. Cell. 73:1059-1065.
32. Slack, R.S., D.J. Belliveau, M. Rosenberg, J. Atwall, R. Aloyz, H. Lochmuller, A. Hagighi, B. Lach, P. Seth, E. Cooper, and F.D. Miller. 1996. Adenovirus-mediated gene transfer of the tumor suppressor, p53 induces apoptosis in postmitotic neurons. J. Cell Biol. 135:1085-1096.
33. Slack, R.S., P.A. Hamel, T.S. Bladen, R.M. Gill, and M.W. McBurney. 1993. Regulated expression of the retinoblastoma gene in differentiating embryonal carcinoma cells. Oncogene. 8:1585-1591.
34. Slack, R.S., and F.D. Miller. 1996a. Retinoblastoma gene in mouse neural development. Dev. Genet. 18:81-91.
35. Slack, R.S., and F.D. Miller. 1996b. Viral vectors for modulating gene expression in neurons. Curr. Opin. Neurobiol. 6:576-583.
36. Slack, R.S., I.S. Skerjanc, B. Lach, J. Craig, K. Jardine, and M.W. McBurney. 1995. Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins. J. Cell Biol. 129:779-788.
37. Szekely, L., W. Jiang, F. Bulicjakus, A. Rosen, N. Ringertz, G. Klein, and K.G. Wiman. 1992. Cell type and differentiation dependent heterogeneity in retinoblastoma protein expression in SCID mouse fetuses. Cell Growth Differ. 3:139-156.
38. Thalmeier, K., H. Snovzik, R. Mertz, E.L. Winnacker, and M. Lipp. 1989. Nuclear factor E2F mediates basic transcription and transactivation by E1A of the human MYC promoter. Genes Dev. 3:527-536.
39. Wald, D.K., and S.C. McLoon. 1995. Immediate differentiation of ganglion cells following mitosis in the developing retina. Neuron. 14:117-124.
40. Wu, W., A. Gloster, and F.D. Miller. 1997. Transcriptional repression of the growth-associated Tα1 α-tubulin gene by target contact. J. Neurosci. Res. 48: 477-487.
41. Zhu, L., S.V.D. Heuvel, K. Helin, A. Fattaey, M. Ewen, D. Livingston, N. Dyson, and E. Harlow. 1993. Inhibition of cell proliferation by p107, a relative of the retinoblasloma protein. Genes Dev. 7:1111-1125.