Chloroplast protein import: Solve the GTPase riddle for entry

Trends in Cell Biology

Volumn 14, Issue 7, 2004, Pages 334-338

  Kessler, Felix ^a   Schnell, Danny J ^b  

^a UNIVERSITY OF NEUCHÂTEL   (Switzerland)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GUANOSINE TRIPHOSPHATASE; PROTEIN PRECURSOR; RECEPTOR PROTEIN; TOC159 PROTEIN; TOC34 PROTEIN; TOC75 PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARABIDOPSIS; CARBOXY TERMINAL SEQUENCE; CELL ORGANELLE; CHLOROPLAST; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC ANALYSIS; HYDROLYSIS KINETICS; MOLECULAR MECHANICS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

ARABIDOPSIS;

EID: 3042799389     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2004.05.004     Document Type: Short Survey

References (28)

1. Keegstra K., Froehlich J.E. Protein import into chloroplasts. Curr. Opin. Plant Biol. 2:1999;471-476
2. Young M.E., et al. GTP promotes the formation of early-import intermediates but is not required during the translocation step of protein import into chloroplasts. Plant Physiol. 121:1999;237-244
3. Becker T., et al. Preprotein recognition by the Toc complex. EMBO J. 23:2004;520-530
4. Bauer J., et al. Essential role of the G-domain in targeting of the protein import receptor atToc159 to the chloroplast outer membrane. J. Cell Biol. 159:2002;845-854
5. Hiltbrunner A., et al. Targeting of an abundant cytosolic form of the protein import receptor at Toc159 to the outer chloroplast membrane. J. Cell Biol. 154:2001;309-316
6. Lee K.H., et al. The M domain of atToc159 plays an essential role in the import of proteins into chloroplasts and chloroplast biogenesis. J. Biol. Chem. 278:2003;36794-36805
7. Smith M.D., et al. The targeting of the atToc159 preprotein receptor to the chloroplast outer membrane is mediated by its GTPase domain and is regulated by GTP. J. Cell Biol. 159:2002;833-843
8. Soll J., Schleiff E. Plant cell biology: Protein import into chloroplasts. Nat. Rev. Mol. Cell Biol. 5:2004;198-208
9. Schleiff E., et al. Structural and guanosine triphosphate/diphosphate requirements for transit peptide recognition by the cytosolic domain of the chloroplast outer envelope receptor, toc34. Biochemistry. 41:2002;1934-1946
10. Sveshnikova N., et al. Toc34 is a preprotein receptor regulated by GTP and phosphorylation. Proc. Natl. Acad. Sci. U. S. A. 97:2000;4973-4978
11. Jelic M., et al. The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase. Biol. Chem. 383:2002;1875-1883
12. Schleiff E., et al. Characterization of the translocon of the outer envelope of chloroplasts. J. Cell Biol. 160:2003;541-551
13. Schleiff E., et al. A GTP-driven motor moves proteins across the outer envelope of chloroplasts. Proc. Natl. Acad. Sci. U. S. A. 100:2003;4604-4609
14. Sun Y.J., et al. Crystal structure of pea Toc34, a novel GTPase of the chloroplast protein translocon. Nat. Struct. Biol. 9:2002;95-100
15. Weibel P., et al. Dimerization of Toc-GTPases at the chloroplast protein import machinery. J. Biol. Chem. 278:2003;37321-37329
16. Wallas T.R., et al. The roles of Toc34 and Toc75 in targeting the Toc159 preprotein receptor to chloroplasts. J. Biol. Chem. 278:2003;44289-44297
17. Chen K., et al. Initial binding of preproteins involving the Toc159 receptor can be bypassed during protein import into chloroplasts. Plant Physiol. 122:2000;813-822
18. Perry S.E., Keegstra K. Envelope membrane proteins that interact with chloroplastic precursor proteins. Plant Cell. 6:1994;93-105
19. Ma Y., et al. Two components of the chloroplast protein import apparatus, IAP86 and IAP75, interact with the transit sequence during the recognition and translocation of precursor proteins at the outer envelope. J. Cell Biol. 134:1996;1-13
20. Kouranov A., Schnell D.J. Analysis of the interactions of preproteins with the import machinery over the course of protein import into chloroplasts. J. Cell Biol. 139:1997;1677-1685
21. Smith M.D., et al. atToc159 is a selective transit peptide receptor for the import of nucleus-encoded chloroplast proteins. J. Cell Biol. 165:2004;323-334
22. Bauer J., et al. The major protein import receptor of plastids is essential for chloroplast biogenesis. Nature. 403:2000;203-207
23. Hiltbrunner, A., et al. AtToc90, a new GTP-binding component of the Arabidopsis chloroplast protein import machinery. Plant Mol. Biol. (in press).
24. Ivanova, Y., et al. (2004) Members of the Toc159 import receptor family represent distinct pathways for protein targeting to plastids. Mol. Biol. Cell 10.1091/mbc.E03-12-0923 (www.molbiolcell.org).
25. Constan D., et al. An outer envelope membrane component of the plastid protein import apparatus plays an essential role in Arabidopsis. Plant J. 38:2004;93-106
26. Jarvis P., et al. An Arabidopsis mutant defective in the plastid general protein import apparatus. Science. 282:1998;100-103
27. Gutensohn M., et al. Functional analysis of two Toc34 homologues in Arabidopsis indicates specialized functions in vivo. Plant J. 23:2000;771-783
28. Nakrieko K.A., et al. Fidelity of targeting to chloroplasts is not affected by removal of the phosphorylation site from the transit peptide. Eur. J. Biochem. 271:2004;509-516