Third BELLE Conference on Toxicological Defense Mechanisms and the Shape of Dose-Response Relationships, Research Triangle Park, NC, United States, 12-14 November 1996: The adaptive response in radiobiology: Evolving insights and implications

Environmental Health Perspectives

Volumn 106, Issue SUPPL. 1, 1998, Pages 277-283

  Wolff, Sheldon ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

Author keywords

Adaptation; Adaptive response; Chromosome aberrations; Cytogenetics; Human lymphocytes; Ionizing radiation; Radiation risks; Repair; Restriction enzymes

Indexed keywords

DOUBLE STRANDED DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN; DNA; MESSENGER RNA;

ADAPTATION; CHROMOSOME ABERRATION; CONFERENCE PAPER; DEFENSE MECHANISM; DNA REPAIR; DNA STRAND BREAKAGE; IONIZING RADIATION; LYMPHOCYTE CULTURE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RADIATION DOSE; RADIATION MUTAGENESIS; RADIOBIOLOGY; ANIMAL; CELL CYCLE; DNA DAMAGE; HUMAN; MOUSE; RADIATION EXPOSURE; REVIEW;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CELL CYCLE; CHROMOSOME ABERRATIONS; DNA; DNA DAMAGE; DNA REPAIR; HUMANS; MICE; RNA, MESSENGER;

EID: 0031977085     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.98106s1277     Document Type: Conference Paper

References (35)

1. United Nations Scientific Committee on the Effects of Atomic Radiation. 1994 Report to the General Assembly, With Annexes. Sources and Effects of Ionizing Radiation, New York:United Nations, 1994.
2. Olivieri G, Bodycote J, Wolff S. Adaptive response of human lymphocytes to low concentrations of radioactive thymidine. Science 223:594-597 (1984).
3. Samson L, Schwartz JL. Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines. Nature 287:861-863 (1980).
4. Samson L, Schwartz JL. The induction of resistance co alkylating damage in mammalian cells. In: Induced Mutagenesis: Molecular Mechanisms and Their Implications for Environmental Protection (Lawrence CW, ed). New York:Plenum Press, 1980;291-309.
5. 3H]thymidine-induced adaptive response of human lymphocytes to subsequent doses of X-rays involves the induction of a chromosomal repair mechanism. Mutagenesis 1:375-380 (1986).
6. Shadley JD, Wolff S. Very low doses of X-rays can cause human lymphocytes to become less susceptible to ionizing radiation. Mutagenesis 2:95-96 (1987).
7. Wolff S, Afzal V, Wiencke JK, Olivieri G, Michaeli A. Human lymphocytes exposed to low doses of ionizing radiations become refractory to high doses of radiation as well as to chemical mutagens that induce double-strand breaks in DNA. Int J Radiat Biol 53:39-47 (1988).
8. Shadley JD, Afzal V, Wolff S. Characterization of the adaptive response to ionizing radiation induced by low doses of X rays to human lymphocytes. Radiat Res 111:511-517 (1987).
9. Youngblom JH, Wiencke JK, Wolff S. Inhibition of the adaptive response of human lymphocytes to very low doses of ionizing radiation by the protein synthesis inhibitor cycloheximide Mutat Res 227:257-261 (1989).
10. Wolff S, Wiencke JK, Afzal V, Youngblom J, Cortes F. The adaptive response of human lymphocytes to very low doses of ionizing radiation: a case of induced chromosomal repair with the induction of specific proteins. In: Low Dose Radiation: Biological Bases of Risk Assessment (Baverstock KF, Stather JW, eds). London:Tylor & Francis, 1989; 446-454.
11. Wolff S. Low-dose exposures and the induction of adaptation, In: Low Dose Irradiation and Biological Defense Mechanisms (Sugahara T, Sagan LA, Aoyama T, eds). Amsterdam:Elsevier, 1992;21-28.
12. Meyers M, Schea RA, Petrowski AE, Seabury H, McLaughlin PW, Lee I, Lee SW, Boothman DA. Role of X-ray-inducible genes and proteins in adaptive survival responses. In: Low Dose Irradiation and Biological Defense Mechanisms (Sugahara T, Sagan LA, Aoyama T, eds). Amsterdam:Elsevier, 1992;263-266.
13. Boothman DA, Meyers M, Fukunaga N, Lee SW. Isolation of X-ray-inducible transcripts from radioresistant human melanoma cells. Proc Nad Acad Sci USA 90:7200-7204 (1992).
14. Liang P, Pardee AB. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257:967-971 (1992).
15. Liang P, Averboukh L, Pardee AB. Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization. Nucleic Acids Res 21:3269-3275 (1993).
16. Meyers M, McCaffrey E, Odegaard J, Boothman D. X-ray-inducible transcripts and altered cell cycle regulation are involved in adaptive survival responses in human cells. Radiat Res 141:110-120 (1994).
17. Sanderson BJS, Morley AA. Exposure of human lymphocytes to ionizing radiation reduces mutagenesis by subsequent ionizing radiation. Mutat Res 164:347-351 (1986).
18. Kelsey KT, Memisoglu A, Frenkel D, Liber HL. Human lymphocytes exposed to low doses of X rays are less susceptible to radiation-induced mutagenesis. Mutat Res 263:197-201 (1991).
19. Rigaud O, Papadopoulo D, Moustacchi E. Decreased deletion mutation in radioadapred human lymphoblasrs. Radiac Res 133:94-101 (1993).
20. Zhou PK, Liu XY, Sun WZ, Zhang YP, Wei K. Cultured mouse SR-1 cells exposed ro low dose of γ-rays become less susceptible to the induction of mutagenesis by radiation as well as bleomycin. Mutagenesis 8:109-111 (1993).
21. Wolff S. The repair of X-ray-induced chromosome aberrations in stimulated and unstimulated human lymphocytes. Mutat Res 15:435-444 (1972).
22. Wolff S. Relation between DNA repair, chromosome aberrations, and sister chromatid exchanges. In: DNA Repair Mechanisms (Hanawalt PC, Friedberg EC, Fox CF, eds). New York:Academic Press, 1978;751-760.
23. 2 stages of the cell cycle. Mutat Res 69:293-305 (1980).
24. D1). Int J Radiat Biol 59:175-184 (1991).
25. Ikushima T. Chromosomal responses to ionizing radiation reminiscent of an adaptive response in cultured Chinese hamster cells. Mutat Res 180:215-221 (1987).
26. Ikushima T. Radio-adaptive response: involvement of induction of specific gene expression by low doses of ionizing radiation. In: Low Dose Irradiation and Biological Defense Mechanisms (Sugahara T, Sagan LA, Aoyama T, eds). Amsterdam:Elsevier, 1992;255-258.
27. Azzam EI, de Toledo SM, Raaphorst GP, Mitchel REJ. Radiation-induced radioresistance in a normal human skin fibroblast cell line. In: Low Dose Irradiation and Biological Defense Mechanisms (Sugahara T, Sagan LA, Aoyama T, eds). Amsterdam:Elsevier, 1992;291-294.
28. Cai L, Liu S-Z. Induction of cytogenetic adaptive response of somatic and germ cells in vivo and in vitro by low-dose X-irradiation. Int J Radiat Biol 58:187-194 (1990).
29. Gaziev AI, Fomenko LA, Kozhanowskaja IK, Sirota NP. Radio-adaptive response in mice chronically exposed to low dose rate of γ-rays. In: Low Dose Irradiation and Biological Defense Mechanisms (Sugahara T, Sagan LA, Aoyama T, eds). Amsterdam:Elsevier, 1992;259-262.
30. Sankaranarayanan K, v. Duyn A, Loos MJ, Natarajan AT. Adaptive response of human lymphocytes to low-level radiation from radioisotopes or X-rays. Mutat Res 211:7-12 (1989).
31. Bosi A, Olivieri G. Variability of the adaptive response to ionizing radiations in humans. Mutat Res 211:13-17 (1989).
32. Wojcik A, Bonk K, Müller W-U, Streffer C. Indications of strain specificity for the induction of adaptive response to ionizing radiation in mice. In: Low Dose Irradiation and Biological Defense Mechanisms (Sugahara T, Sagan LA, Aoyama T, eds). Amsterdam:Elsevier, 1992;311-314.
33. Joiner MC, Lambin P, Malaise EP, Robson T, Arrand JE, Skov KA, Marples B. Hypersensitivity to very-low single doses: its relationship to the adaptive response and induced radioresistance. Mutat Res 358:231-235 (1996).
34. Bhattarcharjee D. Role of radio-adaptation on radiation-induced thymic lymphoma in mice. Mutat Res 358:231-235 (1996).
35. Yonezawa M, Misonoh J, Hosokawa Y. Two types of X-ray-induced radioresistance in mice - presence of 4 dose ranges with distinct biological effects. Mutat Res 358:237-243 (1996).