C3G-mediated suppression of oncogene-induced focus formation in fibroblasts involves inhibition of ERK activation, cyclin a expression and alterations of anchorage-independent growth

Oncogene

Volumn 23, Issue 28, 2004, Pages 4885-4893

  Guerrero, Carmen ^a   Martín Encabo, Susana ^a   Fernández Medarde, Alberto ^a   Santos, Eugenio ^a,b  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b Centro de Investigacion del Cancer   (Spain)

Author keywords

Anchorage independent growth; C3G; Focus formation; Ras; Transformation suppression

Indexed keywords

CYCLIN A; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C3G; RAF PROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG; ONCOPROTEIN; PRIMER DNA;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ARTICLE; BINDING SITE; CATALYSIS; CELL CYCLE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROBLAST; GENE REPRESSION; MOUSE; NONHUMAN; ONCOGENE; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; ANIMAL; CELL ADHESION; CELL DIVISION; CELL STRAIN 3T3; GENE DELETION; GENETICS; HUMAN; METABOLISM; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROTO ONCOGENE; RESTRICTION MAPPING;

ANIMALIA;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CELL ADHESION; CELL DIVISION; CLONING, MOLECULAR; CYCLIN A; DNA PRIMERS; FIBROBLASTS; GENES, RAS; GENES, SIS; GUANINE NUCLEOTIDE-RELEASING FACTOR 2; HUMANS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; ONCOGENE PROTEINS V-RAF; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; SEQUENCE DELETION;

EID: 3042728570     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207622     Document Type: Article

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