-
1
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson M.S., Venanzi E.S., Klein L., Chen Z., Berzins S.P., Turley S.J., von Boehmer H., Bronson R., Dierich A., Benoist C., Mathis D. Projection of an immunological self shadow within the thymus by the aire protein. Science. 298:2002;1395-1401
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
Von Boehmer, H.7
Bronson, R.8
Dierich, A.9
Benoist, C.10
Mathis, D.11
-
2
-
-
0018864218
-
Experimental myasthenia gravis. A murine system
-
Berman P.W., Patrick J. Experimental myasthenia gravis. A murine system. J. Exp. Med. 151:1980;204-223
-
(1980)
J. Exp. Med.
, vol.151
, pp. 204-223
-
-
Berman, P.W.1
Patrick, J.2
-
3
-
-
0033786776
-
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
-
Bielekova B., Goodwin B., Richert N., Cortese I., Kondo T., Afshar G., Gran B., Eaton J., Antel J., Frank J.A., McFarland H.F., Martin R. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat. Med. 6:2000;1167-1175
-
(2000)
Nat. Med.
, vol.6
, pp. 1167-1175
-
-
Bielekova, B.1
Goodwin, B.2
Richert, N.3
Cortese, I.4
Kondo, T.5
Afshar, G.6
Gran, B.7
Eaton, J.8
Antel, J.9
Frank, J.A.10
McFarland, H.F.11
Martin, R.12
-
4
-
-
0023939278
-
Resistance to experimental autoimmune myasthenia gravis in genetically inbred rats. Association with decreased amounts of in situ acetylcholine receptor-antibody complexes
-
Biesecker G., Koffler D. Resistance to experimental autoimmune myasthenia gravis in genetically inbred rats. Association with decreased amounts of in situ acetylcholine receptor-antibody complexes. J. Immunol. 140:1988;3406-3410
-
(1988)
J. Immunol.
, vol.140
, pp. 3406-3410
-
-
Biesecker, G.1
Koffler, D.2
-
5
-
-
1542500767
-
Different patterns of nicotinic acetylcholine receptor subunit transcription in human thymus
-
Bruno R., Sabater L., Tolosa E., Sospedra M., Ferrer-Francesch X., Coll J., Foz M., Melms A., Pujol-Borrell R. Different patterns of nicotinic acetylcholine receptor subunit transcription in human thymus. J. Neuroimmunol. 149:2004;147-159
-
(2004)
J. Neuroimmunol.
, vol.149
, pp. 147-159
-
-
Bruno, R.1
Sabater, L.2
Tolosa, E.3
Sospedra, M.4
Ferrer-Francesch, X.5
Coll, J.6
Foz, M.7
Melms, A.8
Pujol-Borrell, R.9
-
6
-
-
0017755136
-
Immune complexes (IgG and C3) at the motor end-plate in myasthenia gravis: Ultrastructural and light microscopic localization and electrophysiologic correlations
-
Engel A.G., Lambert E.H., Howard F.M. Immune complexes (IgG and C3) at the motor end-plate in myasthenia gravis: ultrastructural and light microscopic localization and electrophysiologic correlations. Mayo Clin. Proc. 52:1977;267-280
-
(1977)
Mayo Clin. Proc.
, vol.52
, pp. 267-280
-
-
Engel, A.G.1
Lambert, E.H.2
Howard, F.M.3
-
7
-
-
0023935543
-
Specificity of the T cell immune response to acetylcholine receptor in experimental autoimmune myasthenia gravis. Response to subunits and synthetic peptides
-
Fujii Y., Lindstrom J. Specificity of the T cell immune response to acetylcholine receptor in experimental autoimmune myasthenia gravis. Response to subunits and synthetic peptides. J. Immunol. 140:1988;1830-1837
-
(1988)
J. Immunol.
, vol.140
, pp. 1830-1837
-
-
Fujii, Y.1
Lindstrom, J.2
-
8
-
-
2442562438
-
Immunogenicity of Torpedo acetylcholine receptor in the context of different rat MHC class II haplotypes and non-MHC genomes
-
Gaertner S., de Graaf K.L., Olsson T., Weissert R. Immunogenicity of Torpedo acetylcholine receptor in the context of different rat MHC class II haplotypes and non-MHC genomes. Immunogenetics. 56:2004;61-64
-
(2004)
Immunogenetics
, vol.56
, pp. 61-64
-
-
Gaertner, S.1
De Graaf, K.L.2
Olsson, T.3
Weissert, R.4
-
9
-
-
0942288397
-
Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters
-
Gotter J., Brors B., Hergenhahn M., Kyewski B. Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J. Exp. Med. 199:2004;155-166
-
(2004)
J. Exp. Med.
, vol.199
, pp. 155-166
-
-
Gotter, J.1
Brors, B.2
Hergenhahn, M.3
Kyewski, B.4
-
10
-
-
0023986105
-
Immunological evidence for a change in subunits of the acetylcholine receptor in developing and denervated rat muscle
-
Gu Y., Hall Z.W. Immunological evidence for a change in subunits of the acetylcholine receptor in developing and denervated rat muscle. Neuron. 1:1988;117-125
-
(1988)
Neuron
, vol.1
, pp. 117-125
-
-
Gu, Y.1
Hall, Z.W.2
-
11
-
-
0033043998
-
Early-onset myasthenia gravis: A recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a
-
Hill M., Beeson D., Moss P., Jacobson L., Bond A., Corlett L., Newsom-Davis J., Vincent A., Willcox N. Early-onset myasthenia gravis: a recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a. Ann. Neurol. 45:1999;224-231
-
(1999)
Ann. Neurol.
, vol.45
, pp. 224-231
-
-
Hill, M.1
Beeson, D.2
Moss, P.3
Jacobson, L.4
Bond, A.5
Corlett, L.6
Newsom-Davis, J.7
Vincent, A.8
Willcox, N.9
-
12
-
-
0035105784
-
Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies
-
Hoch W., McConville J., Helms S., Newsom-Davis J., Melms A., Vincent A. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat. Med. 7:2001;365-368
-
(2001)
Nat. Med.
, vol.7
, pp. 365-368
-
-
Hoch, W.1
McConville, J.2
Helms, S.3
Newsom-Davis, J.4
Melms, A.5
Vincent, A.6
-
13
-
-
0033984067
-
Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells
-
Klein L., Klugmann M., Nave K.A., Tuohy V.K., Kyewski B. Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells. Nat. Med. 6:2000;56-61
-
(2000)
Nat. Med.
, vol.6
, pp. 56-61
-
-
Klein, L.1
Klugmann, M.2
Nave, K.A.3
Tuohy, V.K.4
Kyewski, B.5
-
14
-
-
0036219003
-
T cell response in experimental autoimmune encephalomyelitis (EAE): Role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire
-
Kuchroo V.K., Anderson A.C., Waldner H., Munder M., Bettelli E., Nicholson L.B. T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire. Annu. Rev. Immunol. 20:2002;101-123
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 101-123
-
-
Kuchroo, V.K.1
Anderson, A.C.2
Waldner, H.3
Munder, M.4
Bettelli, E.5
Nicholson, L.B.6
-
15
-
-
0016796265
-
Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs
-
Lennon V.A., Lindstrom J.M., Seybold M.E. Experimental autoimmune myasthenia: a model of myasthenia gravis in rats and guinea pigs. J. Exp. Med. 141:1975;1365-1375
-
(1975)
J. Exp. Med.
, vol.141
, pp. 1365-1375
-
-
Lennon, V.A.1
Lindstrom, J.M.2
Seybold, M.E.3
-
16
-
-
0025857369
-
Recombinant human acetylcholine receptor alpha-subunit induces chronic experimental autoimmune myasthenia gravis
-
Lennon V.A., Lambert E.H., Leiby K.R., Okarma T.B., Talib S. Recombinant human acetylcholine receptor alpha-subunit induces chronic experimental autoimmune myasthenia gravis. J. Immunol. 146:1991;2245-2248
-
(1991)
J. Immunol.
, vol.146
, pp. 2245-2248
-
-
Lennon, V.A.1
Lambert, E.H.2
Leiby, K.R.3
Okarma, T.B.4
Talib, S.5
-
17
-
-
0031879610
-
Molecular and antigenic structure of nicotinic acetylcholine receptors
-
Lindstrom J., Peng X., Kuryatov A., Lee E., Anand R., Gerzanich V., Wang F., Wells G., Nelson M. Molecular and antigenic structure of nicotinic acetylcholine receptors. Ann. N. Y. Acad. Sci. 841:1998;71-86
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.841
, pp. 71-86
-
-
Lindstrom, J.1
Peng, X.2
Kuryatov, A.3
Lee, E.4
Anand, R.5
Gerzanich, V.6
Wang, F.7
Wells, G.8
Nelson, M.9
-
18
-
-
0032719206
-
A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor
-
Madsen L.S., Andersson E.C., Jansson L., krogsgaard M., Andersen C.B., Engberg J., Strominger J.L., Svejgaard A., Hjorth J.P., Holmdahl R., Wucherpfennig K.W., Fugger L. A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor. Nat. Genet. 23:1999;343-347
-
(1999)
Nat. Genet.
, vol.23
, pp. 343-347
-
-
Madsen, L.S.1
Andersson, E.C.2
Jansson, L.3
Krogsgaard, M.4
Andersen, C.B.5
Engberg, J.6
Strominger, J.L.7
Svejgaard, A.8
Hjorth, J.P.9
Holmdahl, R.10
Wucherpfennig, K.W.11
Fugger, L.12
-
20
-
-
0023841883
-
Thymus in myasthenia gravis. Isolation of T-lymphocyte lines specific for the nicotinic acetylcholine receptor from thymuses of myasthenic patients
-
Melms A., Schalke B.C., Kirchner T., Muller-Hermelink H.K., Albert E., Wekerle H. Thymus in myasthenia gravis. Isolation of T-lymphocyte lines specific for the nicotinic acetylcholine receptor from thymuses of myasthenic patients. J. Clin. Invest. 81:1988;902-908
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 902-908
-
-
Melms, A.1
Schalke, B.C.2
Kirchner, T.3
Muller-Hermelink, H.K.4
Albert, E.5
Wekerle, H.6
-
21
-
-
0026575557
-
T cells from normal and myasthenic individuals recognize the human acetylcholine receptor: Heterogeneity of antigenic sites on the alpha-subunit
-
Melms A., Malcherek G., Gern U., Wietholter H., Muller C.A., Schoepfer R., Lindstrom J. T cells from normal and myasthenic individuals recognize the human acetylcholine receptor: heterogeneity of antigenic sites on the alpha-subunit. Ann. Neurol. 31:1992;311-318
-
(1992)
Ann. Neurol.
, vol.31
, pp. 311-318
-
-
Melms, A.1
Malcherek, G.2
Gern, U.3
Wietholter, H.4
Muller, C.A.5
Schoepfer, R.6
Lindstrom, J.7
-
22
-
-
0345332575
-
Maturation of the acetylcholine receptor in skeletal muscle: Regulation of the AChR gamma-to-epsilon switch
-
Missias A.C., Chu G.C., Klocke B.J., Sanes J.R., Merlie J.P. Maturation of the acetylcholine receptor in skeletal muscle: regulation of the AChR gamma-to-epsilon switch. Dev. Biol. 179:1996;223-238
-
(1996)
Dev. Biol.
, vol.179
, pp. 223-238
-
-
Missias, A.C.1
Chu, G.C.2
Klocke, B.J.3
Sanes, J.R.4
Merlie, J.P.5
-
23
-
-
0033049143
-
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
-
Moalem G., Leibowitz-Amit R., Yoles E., Mor F., Cohen I.R., Schwartz M. Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nat. Med. 5:1999;49-55
-
(1999)
Nat. Med.
, vol.5
, pp. 49-55
-
-
Moalem, G.1
Leibowitz-Amit, R.2
Yoles, E.3
Mor, F.4
Cohen, I.R.5
Schwartz, M.6
-
24
-
-
0031902708
-
IL-12 is involved in the induction of experimental autoimmune myasthenia gravis, an antibody mediated disease
-
Moiola L., Galbiati F., Martino G., Amadio S., Brambilla E., Comi G., Vincent A., Grimaldi L.M., Adorini L. IL-12 is involved in the induction of experimental autoimmune myasthenia gravis, an antibody mediated disease. Eur. J. Immunol. 28:1998;2487-2497
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2487-2497
-
-
Moiola, L.1
Galbiati, F.2
Martino, G.3
Amadio, S.4
Brambilla, E.5
Comi, G.6
Vincent, A.7
Grimaldi, L.M.8
Adorini, L.9
-
25
-
-
0037228871
-
Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders
-
Muraro P.A., Wandinger K.P., Bielekova B., Gran B., Marques A., Utz U., McFarland H.F., Jacobson S., Martin R. Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. Brain. 126:2003;20-31
-
(2003)
Brain
, vol.126
, pp. 20-31
-
-
Muraro, P.A.1
Wandinger, K.P.2
Bielekova, B.3
Gran, B.4
Marques, A.5
Utz, U.6
McFarland, H.F.7
Jacobson, S.8
Martin, R.9
-
26
-
-
0037212989
-
Harm or heal-divergent effects of autoimmune neuroinflammation?
-
(author reply 7-8)
-
Olsson T., Lidman O., Piehl F. Harm or heal-divergent effects of autoimmune neuroinflammation? Trends Immunol. 24:2003;5-6. (author reply 7-8)
-
(2003)
Trends Immunol.
, vol.24
, pp. 5-6
-
-
Olsson, T.1
Lidman, O.2
Piehl, F.3
-
27
-
-
0015935638
-
Autoimmune response to acetylcholine receptor
-
Patrick J., Lindstrom J. Autoimmune response to acetylcholine receptor. Science. 180:1973;871-872
-
(1973)
Science
, vol.180
, pp. 871-872
-
-
Patrick, J.1
Lindstrom, J.2
-
28
-
-
0017260528
-
Genetic associations between myasthenia gravis and the HL-A system
-
Pirskanen R. Genetic associations between myasthenia gravis and the HL-A system. J. Neurol. Neurosurg. Psychiatry. 39:1976;23-33
-
(1976)
J. Neurol. Neurosurg. Psychiatry
, vol.39
, pp. 23-33
-
-
Pirskanen, R.1
-
29
-
-
0025762970
-
Acetylcholine receptor-specific T-lymphocyte clones in the normal human immune repertoire: Target epitopes. HLA restriction, and membrane phenotypes
-
Salvetti M., Jung S., Chang S.F., Will H., Schalke B.C., Wekerle H. Acetylcholine receptor-specific T-lymphocyte clones in the normal human immune repertoire: target epitopes. HLA restriction, and membrane phenotypes. Ann. Neurol. 29:1991;508-516
-
(1991)
Ann. Neurol.
, vol.29
, pp. 508-516
-
-
Salvetti, M.1
Jung, S.2
Chang, S.F.3
Will, H.4
Schalke, B.C.5
Wekerle, H.6
-
30
-
-
0031927266
-
Selective impairment of serum antibody repertoires toward muscle and thymus antigens in patients with seronegative and seropositive myasthenia gravis
-
Sharshar T., Lacroix-Desmazes S., Mouthon L., Kaveri S., Gajdos P., Kazatchkine M.D. Selective impairment of serum antibody repertoires toward muscle and thymus antigens in patients with seronegative and seropositive myasthenia gravis. Eur. J. Immunol. 28:1998;2344-2354
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2344-2354
-
-
Sharshar, T.1
Lacroix-Desmazes, S.2
Mouthon, L.3
Kaveri, S.4
Gajdos, P.5
Kazatchkine, M.D.6
-
31
-
-
0016755254
-
Myasthenia gravis: Passive transfer from man to mouse
-
Toyka K.V., Brachman D.B., Pestronk A., Kao I. Myasthenia gravis: passive transfer from man to mouse. Science. 190:1975;397-399
-
(1975)
Science
, vol.190
, pp. 397-399
-
-
Toyka, K.V.1
Brachman, D.B.2
Pestronk, A.3
Kao, I.4
-
32
-
-
17344372846
-
Anatomy of the antigenic structure of a large membrane autoantigen, the muscle-type nicotinic acetylcholine receptor
-
Tzartos S.J., Barkas T., Cung M.T., Mamalaki A., Marraud M., Orlewski P., Papanastasiou D., Sakarellos C., Sakarellos-Daitsiotis M., Tsantili P., Tsikaris V. Anatomy of the antigenic structure of a large membrane autoantigen, the muscle-type nicotinic acetylcholine receptor. Immunol. Rev. 163:1998;89-120
-
(1998)
Immunol. Rev.
, vol.163
, pp. 89-120
-
-
Tzartos, S.J.1
Barkas, T.2
Cung, M.T.3
Mamalaki, A.4
Marraud, M.5
Orlewski, P.6
Papanastasiou, D.7
Sakarellos, C.8
Sakarellos-Daitsiotis, M.9
Tsantili, P.10
Tsikaris, V.11
-
33
-
-
0001707341
-
Localization of the main immunogenic region of human muscle acetylcholine receptor to residues 67-76 of the alpha subunit
-
Tzartos S.J., Kokla A., Walgrave S.L., Conti-Tronconi B.M. Localization of the main immunogenic region of human muscle acetylcholine receptor to residues 67-76 of the alpha subunit. Proc. Natl. Acad. Sci. U. S. A. 85:1988;2899-2903
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 2899-2903
-
-
Tzartos, S.J.1
Kokla, A.2
Walgrave, S.L.3
Conti-Tronconi, B.M.4
-
34
-
-
0036779688
-
Unravelling the pathogenesis of myasthenia gravis
-
Vincent A. Unravelling the pathogenesis of myasthenia gravis. Nat. Rev., Immunol. 2:2002;797-804
-
(2002)
Nat. Rev., Immunol.
, vol.2
, pp. 797-804
-
-
Vincent, A.1
-
35
-
-
0031442102
-
Highly purified oligo-His tagged human recombinant alpha(1)-AChR is immunogenic in vivo and suitable for T cell stimulation in vitro in experimental and human myasthenia gravis
-
Voltz R., Kamm C., Padberg F., Malotka J., Kerschensteiner M., Spuler S., Tzartos S., Dornmair K. Highly purified oligo-His tagged human recombinant alpha(1)-AChR is immunogenic in vivo and suitable for T cell stimulation in vitro in experimental and human myasthenia gravis. J. Neuroimmunol. 80:1997;131-136
-
(1997)
J. Neuroimmunol.
, vol.80
, pp. 131-136
-
-
Voltz, R.1
Kamm, C.2
Padberg, F.3
Malotka, J.4
Kerschensteiner, M.5
Spuler, S.6
Tzartos, S.7
Dornmair, K.8
-
36
-
-
0035555022
-
The genetics of complex autoimmune diseases: Non-MHC susceptibility genes
-
Wanstrat A., Wakeland E. The genetics of complex autoimmune diseases: non-MHC susceptibility genes. Nat. Immunol. 2:2001;802-809
-
(2001)
Nat. Immunol.
, vol.2
, pp. 802-809
-
-
Wanstrat, A.1
Wakeland, E.2
-
37
-
-
0032531157
-
MHC haplotype-dependent regulation of MOG-induced EAE in rats
-
Weissert R., Wallstrom E., Storch M.K., Stefferl A., Lorentzen J., Lassmann H., Linington C., Olsson T. MHC haplotype-dependent regulation of MOG-induced EAE in rats. J. Clin. Invest. 102:1998;1265-1273
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1265-1273
-
-
Weissert, R.1
Wallstrom, E.2
Storch, M.K.3
Stefferl, A.4
Lorentzen, J.5
Lassmann, H.6
Linington, C.7
Olsson, T.8
-
38
-
-
0035877212
-
MHC class II-regulated central nervous system autoaggression and T cell responses in peripheral lymphoid tissues are dissociated in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis
-
Weissert R., de Graaf K.L., Storch M.K., Barth S., Linington C., Lassmann H., Olsson T. MHC class II-regulated central nervous system autoaggression and T cell responses in peripheral lymphoid tissues are dissociated in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. J. Immunol. 166:2001;7588-7599
-
(2001)
J. Immunol.
, vol.166
, pp. 7588-7599
-
-
Weissert, R.1
De Graaf, K.L.2
Storch, M.K.3
Barth, S.4
Linington, C.5
Lassmann, H.6
Olsson, T.7
-
39
-
-
0036644486
-
High immunogenicity of intracellular myelin oligodendrocyte glycoprotein epitopes
-
Weissert R., Kuhle J., de Graaf K.L., Wienhold W., Herrmann M.M., Muller C., Forsthuber T.G., Wiesmuller K.H., Melms A. High immunogenicity of intracellular myelin oligodendrocyte glycoprotein epitopes. J. Immunol. 169:2002;548-556
-
(2002)
J. Immunol.
, vol.169
, pp. 548-556
-
-
Weissert, R.1
Kuhle, J.2
De Graaf, K.L.3
Wienhold, W.4
Herrmann, M.M.5
Muller, C.6
Forsthuber, T.G.7
Wiesmuller, K.H.8
Melms, A.9
-
40
-
-
0035370214
-
Protective autoimmunity is a physiological response to CNS trauma
-
Yoles E., Hauben E., Palgi O., Agranov E., Gothilf A., Cohen A., Kuchroo V., Cohen I.R., Weiner H., Schwartz M. Protective autoimmunity is a physiological response to CNS trauma. J. Neurosci. 21:2001;3740-3748
-
(2001)
J. Neurosci.
, vol.21
, pp. 3740-3748
-
-
Yoles, E.1
Hauben, E.2
Palgi, O.3
Agranov, E.4
Gothilf, A.5
Cohen, A.6
Kuchroo, V.7
Cohen, I.R.8
Weiner, H.9
Schwartz, M.10
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