Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture?

Shock

Volumn 16, Issue 2, 2001, Pages 137-142

  Baechtold, François ^a   Scott, Jeremy A ^b   Markert, Michéle ^a   Mehta, Sanjay ^b   McCormack, David G ^b   Anglada, Frédéric ^c   Galaud, Delphine ^a   Vaglio, Martine ^a   Waeber, Bernard ^a   Feihl, François ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Benzamide; Intestinal perforation; Multiple organ failure; NAD + ADP ribosyltransferase; Rats; Sepsis

Indexed keywords

2,3 DIAMINOPROPIONIC ACID; 2,3-DIAMINOPROPIONIC ACID; ADENOSINE TRIPHOSPHATE; BETA ALANINE; CREATINE KINASE; CREATININE; DRUG DERIVATIVE; ENZYME INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXYGEN; PEROXIDASE; TRIACYLGLYCEROL LIPASE;

ANIMAL; ARTICLE; BLOOD; CECUM; DRUG ANTAGONISM; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYMOLOGY; LIVER FUNCTION TEST; MALE; METABOLISM; MICROBIOLOGY; PRESSURE; RAT; REFERENCE VALUE; SEPSIS; WISTAR RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; BETA-ALANINE; CECUM; CREATINE KINASE; CREATININE; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME INHIBITORS; LIPASE; LIVER FUNCTION TESTS; MALE; NADP; OXYGEN; PARTIAL PRESSURE; PEROXIDASE; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, WISTAR; REFERENCE VALUES; SEPSIS;

EID: 0035432862     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-200116020-00009     Document Type: Article

References (46)

1. Szabo C, Dawson VL: Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion [Review]. Trends Pharmacol Sci 19:287-298, 1998.
2. Wang ZQ, AuerB , Stingl L, Berghammer H, Haidacher D, Schweiger M, Wagner EF: Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev 9:509-520, 1995.
3. de Murcia JM, Niedergang C, Trucco C, Ricoul M, Dutrillaux B, Mark M, Oliver FJ, Masson M, Dierich A, LeMeur M, Walztinger C, Chambon P, de Murcia G: Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci USA 94:7303-7307, 1997.
4. Szabo C, Saunders C, O'Connor M, Salzman AL: Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells. Am J Respir Cell Mol Biol 16:105-109, 1997.
5. Oliver FJ, Menissier-de Murcia J, Nacci C, Decker P, Andriantsitohaina R, Muller S, de la Rubia G, Stoclet JC, de Murcia G: Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice. EMBO J 18:4446-4454, 1999.
6. Szabo C, Lim LHK, Cuzzocrea S, Getting SJ, Zingarelli B, Flower RJ, Salzman AL, Perretti M: Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts anti-inflammatory effects. J Exp Med 186:1041-1049, 1997.
7. Szabo C, Zingarelli B, Salzman AL: Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite. Circ Res 78:1051-1063, 1996.
8. Zingarelli B, Salzman AL, Szabo C: Protective effects of nicotinamide against nitric oxide-mediated delayed vascular failure in endotoxic shock: potential involvement of polyADP ribosyl synthetase. Shock 5:258-264, 1996.
9. Szabo C, Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL: Endothelial dysfunction in a rat model of endotoxic shock: importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J Clin Invest 100:723-735, 1997.
10. Deitch EA: Animal models of sepsis and shock: a review and lessons learned. Shock 9:1-11, 1998.
11. Wichterman KA, Baue AE, Chaudry IH: Sepsis and septic shock: a review of laboratory models and a proposal. J Surg Res 29:189-201, 1980.
12. Scott JA, McCormack DG: Selective in vivo inhibition of inducible nitric oxide synthase in a rat model of sepsis. J Appl Physiol 86:1739-1744, 1999.
13. Gocan NC, Scott JA, Tyml K: Nitric oxide produced via neuronal NOS may impair vasodilatation in septic rat skeletal muscle. Am J Physiol 278:H1480-H1489, 2000.
14. Tyml K, Yu J, McCormack DG: Capillary and arteriolar responses to local vasodilators are impaired in a rat model of sepsis. J Appl Physiol 84:837-844, 1998.
15. Beckman JS, Koppenol WH: Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. [Review]. Am J Physiol 271:C1424-C1437, 1996.
16. Liaudet L, Fishman D, Markert M, Perret C, Feihl F: L-Canavanine improves organ function and tissue adenosine triphosphate levels in rodent endotoxemia. Am J Respir Crit Care Med 155:1643-1648, 1997.
17. Shah GM, Poirier D, Duchaine C, Brochu G, Desnoyers S, Lagueux J, Verreault A, Hoflack JC, Kirkland JB, Poirier GG: Methods for biochemical study of poly(ADP-ribose) metabolism in vitro and in vivo. [Review]. Anal Biochem 227:1-13, 1995.
18. Winer BJ: Statistical principles in experimental design. New York: McGraw-Hill, 1971, pp 172-175.
19. Martin M, Sibbald WJ: Modulation of hemodynamics and organ blood flow by nitric oxide synthase inhibition is not altered in normotensive, septic rats. Am J Respir Crit Care Med 150:1539-1544, 1994.
20. Yu P, Boughner DR, Sibbald WJ, Keys J, Dunmore J, Martin CM: Myocardial collagen changes and edema in rats with hyperdynamic sepsis. Crit Care Med 25:657-662, 1997.
21. Szabo C, Salzman AL, Ischiropoulos H: Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury. FEBS Lett 372:229-232, 1995.
22. Szabo A, Salzman AL, Szabo C: Poly (ADP-ribose) synthetase activation mediates pulmonary microvascular and intestinal mucosal dysfunction in endotoxin shock. Life Sci 63:2133-2139, 1998.
23. Cuzzocrea S, Zingarelli B, Caputi AP: Role of peroxynitrite and poly (ADP-ribosyl) synthetase activation in cardiovascular derangement induced by zymosan in the rat. Life Sci 63:923-933, 1998.
24. Cuzzocrea S, Zingarelli B, Costantino G, Sottile A, Teti D, Caputi AP: Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat. Crit Care Med 27:1517-1523, 1999.
25. Piper RD, Cook DJ, Bone RC, Sibbald WJ: Introducing critical appraisal to studies of animal models investigating novel therapies in sepsis. [Review]. Crit Care Med 24:2059-2070, 1996.
26. Holman JM, Jr, Saba TM: Hepatocyte injury during post-operative sepsis: activated neutrophils as potential mediators. J Leukoc Biol 43:193-203, 1988.
27. Wang P, Ba ZF, Ayala A, Chaudry IH: Hepatocellular dysfunction persists during early sepsis despite increased volume of crystalloid resuscitation. J Trauma 32:389-397, 1992.
28. Doi F, Goya T, Torisu M: Potential role of hepatic macrophages in neutrophil-mediated liver injury in rats with sepsis. Hepatology 17:1086-1094, 1993.
29. Que LG, Kang BH, Huang YC, Piantadosi CA, Chang LY: Anti-intercellular adhesion molecule-1 antibody and intercellular adhesion molecule-1 gene deficiency do not prevent pulmonary neutrophil recruitment in polymicrobial sepsis. Shock 9:304-309, 1998.
30. Beyer AJ, Smalley DM, Shyr YM, Wood JG, Cheung LY: PAF and CD18 mediate neutrophil infiltration in upper gastrointestinal tract during intraabdominal sepsis. Am J Physiol 275:G467-G472, 1998.
31. Yang S, Hauptman JG: The efficacy of heparin and anti-thrombin III in fluid-resuscitated cecal ligation and puncture. Shock 2:433-437, 1994.
32. Smith EFD, Slivjak MJ, Egan JW, Gagnon R, Arleth AJ, Esser KM: Fluid resuscitation improves survival of endotoxemic or septicemic rats: possible contribution of tumor necrosis factor. Pharmacology 46:254-267, 1993.
33. Lundblad R, Giercksky KE: Effect of volume support, antibiotic therapy, and monoclonal anti-endotoxin antibodies on mortality rate and blood concentrations of endothelin and other mediators in fulminant intra-abdominal sepsis in rats. Crit Care Med 23:1382-1390, 1995.
34. Thies RL, Autor AP: Reactive oxygen injury to cultured pulmonary artery endothelial cells: mediation by poly(ADP-ribose) polymerase activation causing NAD depletion and altered energy balance. Arch Biochem Biophys 286: 353-363, 1991.
35. Zingarelli B, Cuzzocrea S, Zsengeller Z, Salzman AL, Szabo C: Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase. Cardiovasc Res 36:205-215, 1997.
36. Pieper AA, Walles T, Wei G, Clements EE, Verma A, Snyder SH, Zweier JL: Myocardial post-ischemic injury is reduced by poly(ADP-ribose) polymerase-1 gene disruption. Mol Med 6:271-282, 2000.
37. Cuzzocrea S, Zingarelli B, Caputi AP: Peroxynitrite-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a non-septic shock model induced by zymosan in the rat. Shock 9:336-340, 1998.
38. Lo EH, Bosque-Hamilton P, Meng W: Inhibition of poly(ADP-ribose) polymerase: reduction of ischemic injury and attenuation of N-methyl-D-aspartate-induced neurotransmitter dysregulation. Stroke 29:830-836, 1998.
39. Ducrocq S, Benjelloun N, Plotkine M, Ben-Ari Y, Charriaut-Marlangue C: Poly(ADP-ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain. J Neurochem 74:2504-2511, 2000.
40. Chatterjee PK, Zacharowski K, Cuzzocrea S, Otto M , Thiemermann C: Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo. FASEB J 14:641-651, 2000.
41. Wray GM, Hinds CJ, Thiemermann C: Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin. Shock 10:13-19, 1998.
42. Liaudet L, Soriano FG, Szabo C: Biology of nitric oxide signaling. Crit Care Med 28:N37-N52, 2000.
43. Lu SC: Regulation of hepatic glutathione synthesis: current concepts and controversies. FASEB J 13:1169-1183, 1999.
44. Pulido EJ, Shames BD, Selzman CH, Barton HA, Banerjee A, Bensard DD, McIntyre RC, Jr: Inhibition of PARS attenuates endotoxin-induced dysfunction of pulmonary vasorelaxation. Am J Physiol 277:L769-L776, 1999.
45. Kristof AS, Goldberg P, Laubach V, Hussain SN: Role of inducible nitric oxide synthase in endotoxin-induced acute lung injury. Am J Respir Crit Care Med 158:1883-1889, 1998.
46. Wang P, Ba ZF, Chaudry IH: Endothelium-dependent relaxation is depressed at the macro-and microcirculatory levels during sepsis. Am J Physiol 269:R988-R994, 1995.