Cytokine profile in response to Cytomegalovirus associated with immune recovery syndrome after highly active antiretroviral therapy

Canadian Journal of Ophthalmology

Volumn 40, Issue 6, 2005, Pages 711-720

  Rios, Lilia S ^a   Vallochi, Adriana L ^a   Muccioli, Cristina ^b   Campos Machado, M A ^a   Belfort Jr , Rubens ^b   Rizzo, Luiz V ^a,c  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c Institute for Investigation in Immunology   (Brazil)

Author keywords

AIDS; CMV retinitis; Cytotoxicity; Immune recovery syndrome

Indexed keywords

ANTIRETROVIRUS AGENT; CYTOKINE; DIDANOSINE; EFAVIRENZ; FOSCARNET; GAMMA INTERFERON; GANCICLOVIR; INDINAVIR; INTERLEUKIN 4; LAMIVUDINE; NELFINAVIR; PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CATARACT; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOMEGALOVIRUS; CYTOTOXICITY; EPIRETINAL MEMBRANE; FEMALE; HIGH RISK PATIENT; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; PAPILLEDEMA; RETINA MACULA CYSTOID EDEMA; UVEITIS; VITREOUS DISEASE;

EID: 30344471040     PISSN: 00084182     EISSN: 17153360     Source Type: Journal    
DOI: 10.1016/S0008-4182(05)80087-0     Document Type: Article

References (30)

1. Autran B, Carcelain G, Li TS, et al. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 1997;277:112-6.
2. Schrier RD, Freeman WR, Wiley CA, McCutchan JA. Immune predispositions for cytomegalovirus retinitis in AIDS. The HNRC Group. J Clin Invest 1995;5:1741-6.
3. Gonczol E, Ianacone J, Ho WZ, Starr S, Meignier B, Plotkin S. Isolated gA/gB glycoprotein complex of human cytomegalovirus envelope induces humoral and cellular immune-responses in human volunteers. Vaccine 1990;8:130-6.
4. Phillips AJ, Tomasec P, Wang EC, Wilkinson GW, Borysiewicz LK. Human cytomegalovirus infection downregulates expression of the cellular aminopeptidases CD10 and CD13. Virology 1998;250:350-8.
5. Bowen EF, Sabin CA, Wilson P, et al. Cytomegalovirus (CMV) viraemia detected by polymerase chain reaction identifies a group of HIV-positive patients at high risk of CMV disease. AIDS 1997;11:889-93.
6. Kuppermann BD, Petty JG, Richman DD, et al. Correlation between CD4+ counts and prevalence of cytomegalovirus retinitis and human immunodeficiency virus-related noninfectious retinal vasculopathy in patients with acquired immunodeficiency syndrome. Am J Ophthalmol 1993;115:575-82.
7. Pertel P, Hirschtick R, Phair J, Chmiel J, Poggensee L, Murphy R. Risk of developing cytomegalovirus retinitis in persons infected with the human immunodeficiency virus. J Acquir Immune Defic Syndr 1992;5:1069-74.
8. Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998;338:853-60.
9. Macdonald JC, Torriani FJ, Morse LS, Karavellas MP, Reed JB, Freeman WR. Lack of reactivation of cytomegalovirus (CMV) retinitis after stopping CMV maintenance therapy in AIDS patients with sustained elevations in CD4 T cells in response to highly active antiretroviral therapy. J Infect Dis 1998;177:1182-7.
10. Betts MR, Ambrozak DR, Douek DC, et al. Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection. J Virol 2001;75:11983-91.
11. Sourdive DJ, Murali-Krishna K, Altman JD, et al. Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection. J Exp Med 1998; 188:71-82.
12. Karavellas MP, Plummer DJ, Macdonald JC, et al. Incidence of immune recovery vitritis in cytomegalovirus retinitis patients following institution of successful highly active antiretroviral therapy. J Infect Dis 1999;179:697-700.
13. Martins SA, Muccioli C, Belfort R Jr, Castelo A. Resolution of microsporidial keratoconjunctivitis in an AIDS patient treated with highly active antiretroviral therapy. Am J Ophthalmol 2001;131:378-9.
14. Ferris FL 3rd, Kassoff A, Bresnick GH, Bailey I. New visual acuity charts for clinical research. Am J Ophthalmol 1982;94: 91-6.
15. Ferris FL 3rd, Sperduto RD. Standardized illumination for visual acuity testing in clinical research. Am J Ophthalmol 1982;94:97-8.
16. Correa-Sales C, Tosta CE, Rizzo LV. The effects of anesthesia with thiopental on T lymphocyte responses to antigen and mitogens in vivo and in vitro. Int J Immunopharmacol 1997; 19:117-28.
17. Komanduri KV, Viswanathan MN, Wieder ED, et al. Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1. Nat Med 1998; 4:953-6.
18. Catania A, Manfredi MG, Airaghi L, et al. Plasma concentration of cytokine antagonists in patients with HIV infection. Neuroimmunomodulation 1994;1:42-9.
19. Gorochov G, Neumann AU, Kereveur A, et al. Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy. Nat Med 1998;4:215-21.
20. Smith KY, Valdez H, Landay A, et al. Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy. J Infect Dis 2000; 181:141-7.
21. Douek DC, McFarland RD, Keiser PH, et al. Changes in thymic function with age and during the treatment of HIV infection. Nature 1998;396:690-5.
22. Rosenberg ES, Billingsley JM, Caliendo AM, et al. Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia. Science 1997;278:1447-50.
23. Connors M, Kovacs JA, Krevat S, et al. HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies. Nat Med 1997;3:533-40.
24. Teixeira L, Valdez H, McCune JM, et al. Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. Aids 2001;15:1749-56.
25. French MA, Mallal SA, Dawkins RL. Zidovudine-induced restoration of cell-mediated immunity to mycobacteria in immunodeficient HIV-infected patients. Aids 1992;6:1293-7.
26. Boivin G, LeBlanc RP Clearance of cytomegalovirus viremia after initiation of highly active antiretroviral therapy. J Infect Dis 2000;181:1216-8.
27. Robinson MR, Reed G, Csaky KG, Polis MA, Whitcup SM. Immune-recovery uveitis in patients with cytomegalovirus retinitis taking highly active antiretroviral therapy. Am J Ophthalmol 2000;130:49-56.
28. Ng TT, Pinching AJ, Guntermann C, Morrow WJ. Molecular immunopathogenesis of HIV infection. Genitourin Med 1996;72:408-18.
29. Cribier B, Rey D, Uhl G, et al. Quantification of hepatitis C virus RNA in peripheral blood mononuclear cells: a comparison between patients chronically infected by HCV and patients coinfected by HIV. Res Virol 1996;147:325-32.
30. Shirai M, Fujinaga R, Masaki T, Berzofsky JA. Impaired development of HIV-1 gp160-specific CD8(+) cytotoxic T cells by a delayed switch from Th1 to Th2 cytokine phenotype in mice with Helicobacter pylori infection. Eur J Immunol 2001;31:516-6.