Accumulation of p53 protein in pterygia is not accompanied by TP53 gene mutation

Experimental Eye Research

Volumn 82, Issue 1, 2006, Pages 91-98

  Schneider, Barbara G ^a   John Aryankalayil, Molykutty ^b   Rowsey, J James ^c   Dushku, Nicolas ^d   Reid, Ted W ^e  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c St Luke's Cataract/Laser Institute   (United States)

^d KAISER PERMANENTE MEDICAL CENTER   (United States)

^e TEXAS TECH UNIVERSITY   (United States)

Author keywords

Laser capture microdissection; p53; Pterygia; RT PCR; TP53

Indexed keywords

DNA; MESSENGER RNA; PROTEIN P53;

ARTICLE; CELL ISOLATION; CODON; CONJUNCTIVA; CONTROLLED STUDY; CORNEA EPITHELIUM; EXON; GENE MUTATION; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MISSENSE MUTATION; PRIORITY JOURNAL; PTERYGIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; EPITHELIAL CELLS; EXONS; GENES, P53; HUMANS; MUTATION, MISSENSE; PTERYGIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 30344467572     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2005.05.006     Document Type: Article

References (53)

1. É. Bálint, and D. Reisman Increased rate of transcription contributes to elevated expression of the mutant p53 gene in Burkitt's lymphoma cells Cancer Res. 56 1996 1648 1653
2. É. Bálint, and K.H. Vousden Activation and activities of the p53 tumour suppressor protein Br. J. Cancer 85 2001 1813 1823
3. J. Bargonetti, and J.J. Manfredi Multiple roles of the tumor suppressor p53 Curr. Opin. Oncol. 14 2002 86 91
4. D.E. Brash, J.A. Rudolph, J.A. Simon, A. Lin, G.J. McKenna, H.P. Baden, A.J. Halperin, and J. Pontén A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma Proc. Natl Acad. Sci. USA 88 1991 10124 10128
5. M.P. Burton, B.G. Schneider, R. Brown, N. Escamilla-Ponce, and M.L. Gulley Comparison of histologic stains for use in PCR analysis of microdissected, paraffin-embedded tissues Biotechniques 24 1998 86 92
6. M.E. Cameron Geographical distribution of pterygia Trans. Ophthalmol. Soc. Aust. 22 1962 67 81
7. I. Chowers, J. Pe'er, E. Zamir, N. Livni, M. Ilsar, and J. Frucht-Pery Proliferative activity and p53 expression in primary and recurrent pterygia Ophthalmologica 108 2001 985 988
8. A. De Vries, E.R. Flores, B. Miranda, H.M. Hsieh, C.T.M. Van Oostrom, J. Sage, and T. Jacks Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function Proc. Natl Acad. Sci. USA 99 2002 2948 2953
9. A. Deffie, H. Wu, V. Reinke, and G. Lozano The tumor suppressor p53 regulates its own transcription Mol. Cell Biol. 13 1993 3415 3423
10. W.G. Dippold, G. Jay, A.B. DeLeo, G. Khoury, and L.J. Old P53 transformation-related proteins: detection by monoclonal antibody in mouse and human cells Cell Biol. 78 1981 1695 1699
11. N. Dushku, and T.W. Reid Immunohistochemical evidence that human pterygia originate from an invasion of vimentin-expressing altered limbal epithelial basal cells Curr. Eye Res. 13 1994 473 481
12. N. Dushku, and T.W. Reid p53 expression in altered limbal basal cells of pingueculae, pterygia, and limbal tumors Curr. Eye Res. 16 1997 1179 1192
13. N. Dushku, S.L. Hatcher, D.M. Albert, and T.W. Reid p53 expression and relation to human papillomavirus infection in pingueculae, pterygia, and limbal tumors Arch. Ophthalmol. 117 1999 1593 1599
14. N. Dushku, M.K. John, G.S. Schultz, and T.W. Reid Pterygia pathogenesis: corneal invasion by matrix metalloproteinase expressing altered limbal epithelial basal cells Arch. Ophthalmol. 119 2001 695 706
15. M. Ebina, A. Martinez, M.J. Birrer, and R.I. Linnoila In situ detection of unexpected patterns of mutant p53 gene expression in non-small cell lung cancers Oncogene 20 2001 2579 2586
16. M. Emmert-Buck, R. Bonner, P.L. Smith, R.F. Chuaqui, Z. Zhuang, S.R. Goldstein, R.A. Weiss, and L. Liotta Laser capture microdissection Science 274 1996 998 1001
17. C.A. Finlay, P.W. Hinds, T.-H. Tan, D. Eliyahu, M. Oren, and A.J. Levine Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life Mol. Cell Biol. 8 1988 531 539
18. A.J. Giaccia, and M.B. Kastan The complexity of p53 modulation: emerging patterns from divergent signals Genes Dev. 12 1998 2973 2983
19. P. Hainaut, and M. Hollstein p53 and human cancer: the first ten thousand mutations Adv. Cancer Res. 77 2000 81 137
20. A.L. Harris Mutant p53 - the commonest genetic abnormality in human cancer? J. Pathol. 162 1990 5 6
21. C.H. Hensel, R.H. Xiang, A.Y. Sakaguchi, and S.L. Naylor Use of the single strand conformation polymorphism technique and PCR to detect p53 gene mutations in small cell lung cancer Oncogene 6 1991 1067 1071
22. R. Iggo, K. Gatter, I. Bartek, D. Lane, and A.L. Harris Increased expression of mutant forms of p53 oncogene in primary lung cancer Lancet 335 1990 675 679
23. M. Kennedy, K.H. Kim, B. Harten, J. Brown, S. Planck, C. Meshul, H. Edelhauser, J.T. Rosenbaum, C.A. Armstrong, and J.C. Ansel Ultraviolet irradiation induces the production of multiple cytokines by human corneal cells Invest. Ophthalmol. Vis. Sci. 38 1997 2483 2491
24. J. Khoo, S.M. Saw, K. Banerjee, S.E. Chia, and D. Tan Outdoor work and the risk of pterygia: a case-control study Int. Ophthalmol. 22 1998 293 298
25. S. Kress, C. Sutter, P.T. Strickland, H. Mukhtar, J. Schweizer, and M. Schwarz Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin Cancer Res. 52 1992 6400 6403
26. D.P. Lane Cancer: p53, guardian of the genome Nature 358 1992 15 16
27. R.M. Lavker, G.S. Dong, S.Z. Cheng, K. Kudoh, G. Costarelis, and T.-T. Sun Relative proliferative rates of limbal and corneal epithelia: implications of corneal epithelial migration, circadian rhythm, and suprabasally located DNA-synthesizing keratinocytes Inv. Ophthalmol. Vis. Sci. 32 1991 1864 1875
28. X. Liu, J. Nishitani, J.L. McQuirter, M.A. Baluda, and N.H. Park The temperature sensitive mutant p53-143ala extends in vitro life span, promotes errors in DNA replication and impairs DNA repair in normal human oral keratinocytes Cell Mol. Biol. 47 2001 1169 1178
29. R. Luthra, B.B. Nemesure, S.-Y. Wu, S.H. Xie, and C. Leske Frequency and risk factors for pterygium in the Barbados eye study Arch. Ophthalmol. 119 2001 1827 1832
30. D.W. Meek Mechanisms of switching on p53: a role for covalent modification? Oncogene 18 1999 7666 7675
31. J. Momand, H.-H. Wu, and G. Dasgupta MDM2-master regulator of the p53 tumor suppressor protein Gene 242 2000 15 29
32. R. Pokroy, Y. Tendler, A. Pollack, O. Zinder, and G. Weisinger p53 expression in the normal murine eye Invest. Ophthalmol. Vis. Sci. 43 2002 1736 1741
33. C. Prives, and P.A. Hall The P53 pathway J. Pathol. 187 1999 112 126
34. T.W. Reid, and N. Dushku Pterygia and limbal epithelial cells: relationship and molecular mechanisms Prog. Retin. Eye Res. 15 1996 297 329
35. D. Reisman, and W.T. Loging Transcriptional regulation of the p53 tumor suppressor gene Semin. Cancer Biol. 8 1998 317 324
36. B. Roy, J. Beamon, E. Bálint, and D. Reisman Transactivation of the human p53 tumor suppressor gene by c-Myc/Max contributes to elevated mutant p53 expression in some tumors Mol. Cell Biol. 14 1994 7805 7815
37. K. Sakaguchi, J.E. Herrera, S. Saito, T. Miki, M. Bustin, A. Vassilev, C.W. Anderson, and E. Appella DNA damage activates p53 through a phosphorylation-acetylation cascade Genes Dev. 12 1998 2831 2841
38. A. Schermer, S. Galvain, and T.-T. Sun Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells J. Cell Biol. 103 1986 49 62
39. B.G. Schneider, D.R. Pulitzer, R.D. Brown, T.J. Prihoda, D. Bostwick, V. Saldivar, H.A. Rodríguez-Martínez, C. Gutiérrez- Díaz, E. M, and P. O'Connell Allelic imbalance in gastric cancer: an affected site on chromosome arm 3p Genes Chromosomes Cancer 13 1995 263 271
40. S. Shimmura, M. Ishioka, K. Hanada, J. Shimazaki, and K. Tsubota Telomerase activity and p53 expression in pterygia Inv. Ophthalmol. Vis. Sci. 41 2000 1364 1369
41. X. Sun, H. Shimizu, and K.-I. Yamamoto Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression Mol. Cell Biol. 15 1995 4489 4496
42. A. Takaoka, S. Hayakawa, H. Yanai, D. Stoiber, H. Negishi, H. Kikuchi, S. Sasaki, K. Imai, T. Shibue, and K. Honda Integration of interferon-α/ β signalling to p53 responses in tumour suppression and antiviral defence Nature 424 2003 516 523
43. G. Tamura, T. Kihana, K. Nomura, M. Terada, T. Sugimura, and S. Hirohashi Detection of frequent p53 gene mutations in primary gastric cancer by cell sorting and polymerase chain reaction single-strand conformation polymorphism analysis Cancer Res. 51 1991 3056 3058
44. D.T. Tan, A.S. Lim, H.S. Goh, and D.R. Smith Abnormal expression of the p53 tumor suppressor gene in the conjunctiva of patients with pterygium Am. J. Ophthalmol. 123 1997 404 405
45. D.T. Tan, W.Y. Tang, Y.P. Liu, H.S. Goh, and D.R. Smith Apoptosis and apoptosis related gene expression in normal conjunctiva and pterygium Br. J. Ophthalmol. 84 2000 212 216
46. H.R. Taylor, S.K. West, F.S. Rosenthal, B.M. Munoz, H.S. Newland, and E.A. Emmett Corneal changes associated with chronic UV irradiation Arch. Ophthalmol. 107 1989 1481 1484
47. Y. Ueda, S. Kanazawa, T. Kitaoka, Y. Dake, A. Ohira, A.M. Ouertani, and T. Amemiya Immunohistochemical study of p53, p21 and PCNA in pterygium Acta Histochem. 103 2001 159 165
48. B. Vogelstein, D. Lane, and A.J. Levine Surfing the p53 network Nature 408 2000 307 310
49. K.H. Vousden, and X. Lu Live or let die: the cell's response to p53 Nat. Rev. Cancer 2 2002 594 604
50. Z.-G. Wei, R.-L. Wu, R.M. Lavker, and T.-T. Sun In vitro growth and differentiation of rabbit bulbar, fornix, and palpebral conjunctival epithelia. Implications on conjunctival epithelial transdifferentiation and stem cells Inv. Ophthalmol. Vis. Sci. 34 1993 1814 1828
51. O. Weinstein, G. Rosenthal, H. Zirkin, T. Monos, T. Lifshitz, and S. Argov Overexpression of p53 tumor suppressor gene in pterygia Eye 16 2002 619 621
52. H.-H. Wu, and G. Lozano NF-kB activation of p53 J. Biol. Chem. 13 1994 3145 3423
53. A. Ziegler, D.J. Leffell, S. Kunala, H.W. Sharma, M. Gailani, J.A. Simon, A.J. Halperin, H.P. Baden, P.E. Shapiro, and A.E. Bale Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers Proc. Natl Acad. Sci. USA 90 1993 4216 4220