Neuroprotective effects of tacrolimus (FK506) in a model of ischemic cortical cell cultures: Role of glutamate uptake and FK506 binding protein 12 kDa

Neuroscience

Volumn 137, Issue 1, 2006, Pages 231-239

  Labrande, C ^a   Velly, L ^b   Canolle, B ^a   Guillet, B ^a   Masmejean, F ^c   Nieoullon, A ^c   Pisano, Pascale ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b TIMONE HOSPITAL   (France)

^c CNRS   (France)

Author keywords

Immunophilins; Immunosuppressive drugs; Neuroprotection; Oxygen glucose deprivation

Indexed keywords

3 (3 PYRIDYL) 1 PROPYL 1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINE CARBOXYLATE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; FK 506 BINDING PROTEIN; GLUCOSE; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; IMMUNOPHILIN; IMMUNOSUPPRESSIVE AGENT; LACTATE DEHYDROGENASE; NEUROPROTECTIVE AGENT; OXYGEN; PROTEIN INHIBITOR; PYRROLIDINE DERIVATIVE; RAPAMYCIN; TACROLIMUS; THREO 3 METHYL GLUTAMATE; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER 1;

AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN PERFUSION; CELL COUNT; CELL CULTURE; CONTROLLED STUDY; ENZYME RELEASE; FETUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; MOLECULAR WEIGHT; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REOXYGENATION;

ANIMALS; ASTROCYTES; CELLS, CULTURED; CEREBRAL CORTEX; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; REPERFUSION INJURY; TACROLIMUS; TACROLIMUS BINDING PROTEINS;

EID: 29744459905     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.08.080     Document Type: Article

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