메뉴 건너뛰기




Volumn 12, Issue 1, 2006, Pages 39-48

Natural history of seminiferous tubule degeneration in Klinefelter syndrome

Author keywords

Azoospermia; Infertility; Klinefelter syndrome; Sertoli cells; Testes

Indexed keywords

FOLLITROPIN; INHIBIN B; LUTEINIZING HORMONE; TESTOSTERONE;

EID: 29544435187     PISSN: 13554786     EISSN: 14602369     Source Type: Journal    
DOI: 10.1093/humupd/dmi039     Document Type: Review
Times cited : (243)

References (110)
  • 3
    • 0030834572 scopus 로고    scopus 로고
    • Serum inhibin B in healthy pubertal and adolescent boys: Relation to age, stage of puberty, and fullicle-stimulating hormone, luteinizing hormone, testosterone, and estradiol levels
    • Andersson AM, Juul A, Petersen JH, Muller J, Groome NP and Skakkebaek NE (1997) Serum inhibin B in healthy pubertal and adolescent boys: Relation to age, stage of puberty, and fullicle-stimulating hormone, luteinizing hormone, testosterone, and estradiol levels. J Clin Endocrinol Metab 82,3976-3981.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3976-3981
    • Andersson, A.M.1    Juul, A.2    Petersen, J.H.3    Muller, J.4    Groome, N.P.5    Skakkebaek, N.E.6
  • 4
    • 0032467978 scopus 로고    scopus 로고
    • Different roles of prepubertal and postpubertal germ cells and Sertoli cells in the regulation of serum inhibin B levels
    • Andersson AM, Muller J and Skakkebaek NE (1998a) Different roles of prepubertal and postpubertal germ cells and Sertoli cells in the regulation of serum inhibin B levels. J Clin Endocrinol Metab 83,4451-4458.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 4451-4458
    • Andersson, A.M.1    Muller, J.2    Skakkebaek, N.E.3
  • 6
    • 0031080114 scopus 로고    scopus 로고
    • Different strategies of X-inactivation in germinal and somatic cells: Histone H4 underacetylation does not mark the inactive X chromosome in the mouse male germline
    • Armstrong SJ, Hulten MA, Keohane AM and Turner BM (1997) Different strategies of X-inactivation in germinal and somatic cells: Histone H4 underacetylation does not mark the inactive X chromosome in the mouse male germline. Exp Cell Res 230,399-402.
    • (1997) Exp Cell Res , vol.230 , pp. 399-402
    • Armstrong, S.J.1    Hulten, M.A.2    Keohane, A.M.3    Turner, B.M.4
  • 9
    • 0018830374 scopus 로고
    • Fetal gonadal histology in XXXXY, XYY and XXX syndromes
    • Autio-Harmainen H, Rapola J and Aula P (1980) Fetal gonadal histology in XXXXY, XYY and XXX syndromes. Clin Genet 18,1-5.
    • (1980) Clin Genet , vol.18 , pp. 1-5
    • Autio-Harmainen, H.1    Rapola, J.2    Aula, P.3
  • 10
    • 85045484695 scopus 로고
    • A morphological distinction between neurones of the male and female, and the behaviour of the nucleolar satellite during accelerated nucleoprotein synthesis
    • Barr ML and Bertram, EG (1949) A morphological distinction between neurones of the male and female, and the behaviour of the nucleolar satellite during accelerated nucleoprotein synthesis. Nature 163,676-677.
    • (1949) Nature , vol.163 , pp. 676-677
    • Barr, M.L.1    Bertram, E.G.2
  • 11
    • 0036163776 scopus 로고    scopus 로고
    • Biopsied testis cells of four 47,XXY patients: Fluorescence in-situ hybridization and ICSI results
    • Bergere M, Wainer R, Nataf V, Bailly M, Gombault M, Ville Y and Selva J (2002) Biopsied testis cells of four 47,XXY patients: Fluorescence in-situ hybridization and ICSI results. Hum Reprod 17,32-37.
    • (2002) Hum Reprod , vol.17 , pp. 32-37
    • Bergere, M.1    Wainer, R.2    Nataf, V.3    Bailly, M.4    Gombault, M.5    Ville, Y.6    Selva, J.7
  • 12
    • 0035014112 scopus 로고    scopus 로고
    • Meiotic behaviour of the sex chromosomes in three patients with sex chromosome anomalies (47,XXY, mosaic 46, XY/47,XXY and 47,XYY) assessed by fluorescence in-situ hybridization
    • Blanco J, Egozcue J and Vidal F (2001) Meiotic behaviour of the sex chromosomes in three patients with sex chromosome anomalies (47,XXY, mosaic 46, XY/47,XXY and 47,XYY) assessed by fluorescence in-situ hybridization. Hum Reprod 16,887-892.
    • (2001) Hum Reprod , vol.16 , pp. 887-892
    • Blanco, J.1    Egozcue, J.2    Vidal, F.3
  • 13
    • 0037326103 scopus 로고    scopus 로고
    • Prenatal and postnatal prevalence of Klinefelter syndrome: A national registry study
    • Bojesen A, Juul S and Gravholt CH (2003) Prenatal and postnatal prevalence of Klinefelter syndrome: A national registry study. J Clin Endocrinol Metab 88,622-626.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 622-626
    • Bojesen, A.1    Juul, S.2    Gravholt, C.H.3
  • 15
    • 0025961771 scopus 로고
    • A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome
    • Brown CJ, Ballabio A, Rupert JL, Lafreniere RG, Grompe M, Tonlorenzi R and Willard HF (1991) A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 349,38-44.
    • (1991) Nature , vol.349 , pp. 38-44
    • Brown, C.J.1    Ballabio, A.2    Rupert, J.L.3    Lafreniere, R.G.4    Grompe, M.5    Tonlorenzi, R.6    Willard, H.F.7
  • 16
    • 0000051626 scopus 로고
    • Unpaired sex chromosomes and gametogenic failure
    • Burgoyne PS and Mahadevaiah, SK (1993) Unpaired sex chromosomes and gametogenic failure. Chromosomes Today 11,243-263.
    • (1993) Chromosomes Today , vol.11 , pp. 243-263
    • Burgoyne, P.S.1    Mahadevaiah, S.K.2
  • 17
    • 0019439244 scopus 로고
    • Venous thromboembolic disease in Klinefelter's syndrome
    • Campbell WA and Price WH (1981) Venous thromboembolic disease in Klinefelter's syndrome. Clin Genet 19,275-280.
    • (1981) Clin Genet , vol.19 , pp. 275-280
    • Campbell, W.A.1    Price, W.H.2
  • 18
    • 0033594960 scopus 로고    scopus 로고
    • Heterogeneous gene expression from the inactive X chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others
    • Carrel L and Willard HF (1999) Heterogeneous gene expression from the inactive X chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others. Proc Natl Acad Sci USA 96,7364-7369.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7364-7369
    • Carrel, L.1    Willard, H.F.2
  • 19
    • 15244353967 scopus 로고    scopus 로고
    • X-inactivation profile reveals extensive variability in X-linked gene expression in females
    • Carrel L and Willard HF (2005) X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 434,400-404.
    • (2005) Nature , vol.434 , pp. 400-404
    • Carrel, L.1    Willard, H.F.2
  • 20
  • 21
    • 0030024760 scopus 로고    scopus 로고
    • Increased incidence of hyperhaploid 24, XY spermatozoa detected by three-colour FISH in a 46,XY/47,XXY male
    • Chevret E, Rousseaux S, Monteil M, Usson Y, Cozzi J, Pelletier R and Sele B (1996) Increased incidence of hyperhaploid 24, XY spermatozoa detected by three-colour FISH in a 46,XY/47,XXY male. Hum Genet 97,171-175.
    • (1996) Hum Genet , vol.97 , pp. 171-175
    • Chevret, E.1    Rousseaux, S.2    Monteil, M.3    Usson, Y.4    Cozzi, J.5    Pelletier, R.6    Sele, B.7
  • 23
    • 0037326355 scopus 로고    scopus 로고
    • Longitudinal studies of inhibin B levels in boys and young adults with Klinefelter syndrome
    • Christiansen P, Andersson AM and Skakkebaek NE (2003) Longitudinal studies of inhibin B levels in boys and young adults with Klinefelter syndrome. J Clin Endocrinol Metab 88,888-891.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 888-891
    • Christiansen, P.1    Andersson, A.M.2    Skakkebaek, N.E.3
  • 25
    • 0034754903 scopus 로고    scopus 로고
    • Testicular tissue extraction in a young male with 47,XXY Klinefelter's syndrome: Potential strategy for preservation of fertility
    • Damani MN, Mittal R and Oates RD (2001) Testicular tissue extraction in a young male with 47,XXY Klinefelter's syndrome: Potential strategy for preservation of fertility. Fertil Steril 76,1054-1056.
    • (2001) Fertil Steril , vol.76 , pp. 1054-1056
    • Damani, M.N.1    Mittal, R.2    Oates, R.D.3
  • 26
    • 5144219565 scopus 로고    scopus 로고
    • Assisted reproductive techniques in patients with Klinefelter syndrome: A critical review
    • Denschlag D, Tempfer C, Kunze M, Wolff G and Keck C (2004) Assisted reproductive techniques in patients with Klinefelter syndrome: A critical review. Fertil Steril 82,775-779.
    • (2004) Fertil Steril , vol.82 , pp. 775-779
    • Denschlag, D.1    Tempfer, C.2    Kunze, M.3    Wolff, G.4    Keck, C.5
  • 27
    • 1842868538 scopus 로고    scopus 로고
    • Meiosis and Klinefelter's syndrome
    • Egozcue J, Blanco J and Vidal F (2002) Meiosis and Klinefelter's syndrome. Hum Reprod 17,3006-3007.
    • (2002) Hum Reprod , vol.17 , pp. 3006-3007
    • Egozcue, J.1    Blanco, J.2    Vidal, F.3
  • 28
    • 0036858766 scopus 로고    scopus 로고
    • Testicular sonography in men with Klinefelter syndrome shows irregular echogenicity and blood flow of high resistance
    • Ekerhovd E and Westlander G (2002) Testicular sonography in men with Klinefelter syndrome shows irregular echogenicity and blood flow of high resistance. J Assist Reprod Genet 19,517-522.
    • (2002) J Assist Reprod Genet , vol.19 , pp. 517-522
    • Ekerhovd, E.1    Westlander, G.2
  • 30
    • 0001213315 scopus 로고
    • The prepubertal testicular lesion in chromatin-positive Klinefelter's syndrome (primary micro-orchidism) as seen in mentally handicapped children
    • Ferguson-Smith MA (1959) The prepubertal testicular lesion in chromatin-positive Klinefelter's syndrome (primary micro-orchidism) as seen in mentally handicapped children. Lancet 1,219-222.
    • (1959) Lancet , vol.1 , pp. 219-222
    • Ferguson-Smith, M.A.1
  • 32
    • 0031737995 scopus 로고    scopus 로고
    • High incidence of sperm sex chromosomes aneuploidies in two patients with Klinefelter's syndrome
    • Foresta C, Galeazzi C, Bettella A, Stella M and Scandellari C (1998) High incidence of sperm sex chromosomes aneuploidies in two patients with Klinefelter's syndrome. J Clin Endocrinol Metab 83,203-205.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 203-205
    • Foresta, C.1    Galeazzi, C.2    Bettella, A.3    Stella, M.4    Scandellari, C.5
  • 34
    • 0015144244 scopus 로고
    • Dimorphism in sex chromatin pattern of Sertoli cells in adults with Klinefelter's syndrome: Correlation with 2 types of "Sertoli-cell-only" tubules
    • Froland A and Skakkebaek NE (1971) Dimorphism in sex chromatin pattern of Sertoli cells in adults with Klinefelter's syndrome: Correlation with 2 types of "Sertoli-cell-only" tubules. J Clin Endocrinol Metab 33,683-687.
    • (1971) J Clin Endocrinol Metab , vol.33 , pp. 683-687
    • Froland, A.1    Skakkebaek, N.E.2
  • 36
    • 85003173488 scopus 로고
    • Hyalinization of the seminiferous tubules associated with normal or failing Leydig-cell function. Microscopic picture in the testis and associated changes in the breast
    • Heller CG and Nelson WO (1945) Hyalinization of the seminiferous tubules associated with normal or failing Leydig-cell function. Microscopic picture in the testis and associated changes in the breast. J Clin Endocrinol 5,1-33.
    • (1945) J Clin Endocrinol , vol.5 , pp. 1-33
    • Heller, C.G.1    Nelson, W.O.2
  • 37
    • 0025756519 scopus 로고
    • Fertile male mice with three sex cbromosomes: Evidence that infertility in XYY male mice is an effect of two Y chromosomes
    • Hunt PA and Eicher EM (1991) Fertile male mice with three sex cbromosomes: Evidence that infertility in XYY male mice is an effect of two Y chromosomes. Chromosoma 100,293-299.
    • (1991) Chromosoma , vol.100 , pp. 293-299
    • Hunt, P.A.1    Eicher, E.M.2
  • 40
    • 33747686159 scopus 로고
    • A case of human intersexuality having a possible XXY sex-determining mechanism
    • Jacobs PA and Strong JA (1959) A case of human intersexuality having a possible XXY sex-determining mechanism. Nature 183,302-303.
    • (1959) Nature , vol.183 , pp. 302-303
    • Jacobs, P.A.1    Strong, J.A.2
  • 41
    • 0037376848 scopus 로고    scopus 로고
    • The roles of supernumerical X chromosomes and XIST expression in testicular germ cell tumors
    • Kawakami T, Okamoto K, Sugihara H, Hattori T, Reeve AE, Ogawa O and Okada Y (2003) The roles of supernumerical X chromosomes and XIST expression in testicular germ cell tumors. J Urol 169,1546-1552.
    • (2003) J Urol , vol.169 , pp. 1546-1552
    • Kawakami, T.1    Okamoto, K.2    Sugihara, H.3    Hattori, T.4    Reeve, A.E.5    Ogawa, O.6    Okada, Y.7
  • 42
    • 0026706093 scopus 로고
    • Spontaneous degeneration of germ cells in normal rat testis: Assessment of cell types and frequency during the spermatogenic cycle
    • Kerr JB (1992) Spontaneous degeneration of germ cells in normal rat testis: Assessment of cell types and frequency during the spermatogenic cycle. J Reprod Fertil 95,825-830.
    • (1992) J Reprod Fertil , vol.95 , pp. 825-830
    • Kerr, J.B.1
  • 43
    • 0028222568 scopus 로고
    • Klinefelter's syndrome: New and rapid diagnosis by PCR analysis of XIST gene expression
    • Kleinheinz A and Schulze W (1994) Klinefelter's syndrome: New and rapid diagnosis by PCR analysis of XIST gene expression. Andrologia 26,127-129.
    • (1994) Andrologia , vol.26 , pp. 127-129
    • Kleinheinz, A.1    Schulze, W.2
  • 44
    • 85003166195 scopus 로고
    • Syndrome characterized by gynecomastia, aspermatogenesis without A-Leydigism, and increased excretion of follicle-stimulating hormone
    • Klinefelter HF, Reifenstein EC and Albright F (1942) Syndrome characterized by gynecomastia, aspermatogenesis without A-Leydigism, and increased excretion of follicle-stimulating hormone. J Clin Endocrinol 2,615-627.
    • (1942) J Clin Endocrinol , vol.2 , pp. 615-627
    • Klinefelter, H.F.1    Reifenstein, E.C.2    Albright, F.3
  • 46
    • 0026995857 scopus 로고
    • The influence of testosterone substitution on bone mineral density in patients with Klinefelter's syndrome
    • Kubler A, Schulz G, Cordes U, Beyer J and Krause U (1992) The influence of testosterone substitution on bone mineral density in patients with Klinefelter's syndrome. Exp Clin Endocrinol 100, 129-132.
    • (1992) Exp Clin Endocrinol , vol.100 , pp. 129-132
    • Kubler, A.1    Schulz, G.2    Cordes, U.3    Beyer, J.4    Krause, U.5
  • 47
    • 1942472654 scopus 로고    scopus 로고
    • Inhibin B and anti-Mullerian hormone, but not testosterone levels, are normal in infants with nonmosaic Klinefelter syndrome
    • Lahlou N, Fennoy I, Carel JC and Roger M (2004) Inhibin B and anti-Mullerian hormone, but not testosterone levels, are normal in infants with nonmosaic Klinefelter syndrome. J Clin Endocrinol Metab 89,1864-1868.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1864-1868
    • Lahlou, N.1    Fennoy, I.2    Carel, J.C.3    Roger, M.4
  • 50
    • 1242296373 scopus 로고    scopus 로고
    • Progressive depletion of germ cells in a man with nonmosaic Klinefelter's syndrome: Optimal time for sperm recovery
    • Lin YM, Huang WJ, Lin JS and Kuo PL (2004) Progressive depletion of germ cells in a man with nonmosaic Klinefelter's syndrome: Optimal time for sperm recovery. Urology 63,380-381.
    • (2004) Urology , vol.63 , pp. 380-381
    • Lin, Y.M.1    Huang, W.J.2    Lin, J.S.3    Kuo, P.L.4
  • 51
    • 0030840990 scopus 로고    scopus 로고
    • X inactivation in human testicular tumors. XIST expression and androgen receptor methylation status
    • Looijenga LH, Gillis AJ, van Gurp RJ, Verkerk AJ and Oosterhuis JW (1997) X inactivation in human testicular tumors. XIST expression and androgen receptor methylation status. Am J Pathol 151,581-590.
    • (1997) Am J Pathol , vol.151 , pp. 581-590
    • Looijenga, L.H.1    Gillis, A.J.2    van Gurp, R.J.3    Verkerk, A.J.4    Oosterhuis, J.W.5
  • 54
    • 0036280070 scopus 로고    scopus 로고
    • Prognostic value of the clinical and laboratory evaluation in patients with nonmosaic Klinefelter syndrome who are receiving assisted reproductive therapy
    • Madgar I, Dor J, Weissenberg R, Raviv G, Menashe Y and Levron J (2002) Prognostic value of the clinical and laboratory evaluation in patients with nonmosaic Klinefelter syndrome who are receiving assisted reproductive therapy. Fertil Steril 77,1167-1169.
    • (2002) Fertil Steril , vol.77 , pp. 1167-1169
    • Madgar, I.1    Dor, J.2    Weissenberg, R.3    Raviv, G.4    Menashe, Y.5    Levron, J.6
  • 55
    • 0036159351 scopus 로고    scopus 로고
    • Early postnatal treatment of hypogonadotropic hypogonadism with recombinant human FSH and LH
    • Main KM, Schmidt IM, Toppari J and Skakkebaek NE (2002) Early postnatal treatment of hypogonadotropic hypogonadism with recombinant human FSH and LH. Eur J Endocrinol 146,75-79.
    • (2002) Eur J Endocrinol , vol.146 , pp. 75-79
    • Main, K.M.1    Schmidt, I.M.2    Toppari, J.3    Skakkebaek, N.E.4
  • 56
    • 0014330110 scopus 로고
    • Chromatin-positive Klinefelter's syndrome. A quantitative analysis of spermatogonial deficiency at 3, 4, and 12 months of age
    • Mikamo K, Aguercif M, Hazeghi P and Martin-Du PR (1968) Chromatin-positive Klinefelter's syndrome. A quantitative analysis of spermatogonial deficiency at 3, 4, and 12 months of age. Fertil Steril 19,731-739.
    • (1968) Fertil Steril , vol.19 , pp. 731-739
    • Mikamo, K.1    Aguercif, M.2    Hazeghi, P.3    Martin-Du, P.R.4
  • 57
    • 0016218356 scopus 로고
    • Sex-chromosome pairing and male fertility
    • Miklos GL (1974) Sex-chromosome pairing and male fertility. Cytogenet Cell Genet 13,558-577.
    • (1974) Cytogenet Cell Genet , vol.13 , pp. 558-577
    • Miklos, G.L.1
  • 58
    • 0032931007 scopus 로고    scopus 로고
    • Meiotic aneuploidy in the XXY mouse: Evidence that a compromised testicular environment increases the incidence of meiotic errors
    • Mroz K, Hassold TJ and Hunt PA (1999) Meiotic aneuploidy in the XXY mouse: Evidence that a compromised testicular environment increases the incidence of meiotic errors. Hum Reprod 14,1151-1156.
    • (1999) Hum Reprod , vol.14 , pp. 1151-1156
    • Mroz, K.1    Hassold, T.J.2    Hunt, P.A.3
  • 59
    • 0029004246 scopus 로고
    • Quantified testicular histology in boys with sex chromosome abnormalities
    • Muller J, Skakkebaek NE and Ratcliffe SG (1995) Quantified testicular histology in boys with sex chromosome abnormalities. Int J Androl 18,57-62.
    • (1995) Int J Androl , vol.18 , pp. 57-62
    • Muller, J.1    Skakkebaek, N.E.2    Ratcliffe, S.G.3
  • 61
    • 16744367800 scopus 로고    scopus 로고
    • Klinefelter-like phenotype and primary infertility in a male with a paracentric Xq inversion
    • Nemeth AH, Gallen IW, Crocker M, Levy E and Maher E (2002) Klinefelter-like phenotype and primary infertility in a male with a paracentric Xq inversion. J Med Genet 39, E28.
    • (2002) J Med Genet , vol.39
    • Nemeth, A.H.1    Gallen, I.W.2    Crocker, M.3    Levy, E.4    Maher, E.5
  • 62
    • 0020038913 scopus 로고
    • Hyperplasia and the immature appearance of Sertoli cells in primary testicular disorders
    • Nistal M, Paniagua R, Abaurra MA and Santamaria L (1982) Hyperplasia and the immature appearance of Sertoli cells in primary testicular disorders. Hum Pathol 13,3-12.
    • (1982) Hum Pathol , vol.13 , pp. 3-12
    • Nistal, M.1    Paniagua, R.2    Abaurra, M.A.3    Santamaria, L.4
  • 65
    • 14644396631 scopus 로고    scopus 로고
    • Testicular germ-cell tumours in a broader perspective
    • Oosterhuis JW and Looijenga LH (2005) Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer 5,210-222.
    • (2005) Nat Rev Cancer , vol.5 , pp. 210-222
    • Oosterhuis, J.W.1    Looijenga, L.H.2
  • 67
    • 0024951826 scopus 로고
    • Molecular studies of the sex chromosomes in human testicular cancer: Pronounced changes in X and Y chromosome dosage in some tumors
    • Peltomaki P, Halme A, and de la Chapelle A (1989) Molecular studies of the sex chromosomes in human testicular cancer: Pronounced changes in X and Y chromosome dosage in some tumors. Genes Chromosomes Cancer 1,42-47.
    • (1989) Genes Chromosomes Cancer , vol.1 , pp. 42-47
    • Peltomaki, P.1    Halme, A.2    de la Chapelle, A.3
  • 72
    • 0034064385 scopus 로고    scopus 로고
    • Germ cell suicide: New insights into apoptosis during spermatogenesis
    • Print CG and Loveland KL (2000) Germ cell suicide: New insights into apoptosis during spermatogenesis. Bioessays 22,423-430.
    • (2000) Bioessays , vol.22 , pp. 423-430
    • Print, C.G.1    Loveland, K.L.2
  • 73
    • 0020450574 scopus 로고
    • The sexual development of boys with the chromosome constitution 47, XXY (Klinefelter's syndrome)
    • Ratcliffe SG (1982) The sexual development of boys with the chromosome constitution 47,XXY (Klinefelter's syndrome). Clin Endocrinol Metab 11,703-716.
    • (1982) Clin Endocrinol Metab , vol.11 , pp. 703-716
    • Ratcliffe, S.G.1
  • 74
    • 0022842354 scopus 로고
    • Edinburgh study of growth and development of children with sex chromosome abnormalities. III
    • Ratcliffe SG, Murray L and Teague P (1986) Edinburgh study of growth and development of children with sex chromosome abnormalities. III. Birth Defects Orig Artic Ser 22,73-118.
    • (1986) Birth Defects Orig Artic Ser , vol.22 , pp. 73-118
    • Ratcliffe, S.G.1    Murray, L.2    Teague, P.3
  • 75
    • 0033024592 scopus 로고    scopus 로고
    • Androgen insensitivity syndrome: An immunohistochemical, ultrastructural, and morphometric study
    • Regadera J, Martinez-Garcia F, Paniagua R and Nistal M (1999) Androgen insensitivity syndrome: An immunohistochemical, ultrastructural, and morphometric study. Arch Pathol Lab Med 123,225-234.
    • (1999) Arch Pathol Lab Med , vol.123 , pp. 225-234
    • Regadera, J.1    Martinez-Garcia, F.2    Paniagua, R.3    Nistal, M.4
  • 76
    • 1542681295 scopus 로고    scopus 로고
    • Regulation of spermatogenesis
    • Rey R (2003) Regulation of spermatogenesis. Endocr Dev 5,38-55.
    • (2003) Endocr Dev , vol.5 , pp. 38-55
    • Rey, R.1
  • 78
    • 0033891355 scopus 로고    scopus 로고
    • A 47,XXY fetus conceived after ICSI of spermatozoa from a patient with non-mosaic Klinefelter's syndrome: Case report
    • Ron-El R, Strassburger D, Gelman-Kohan S, Friedler S, Raziel A and Appelman Z (2000) A 47, XXY fetus conceived after ICSI of spermatozoa from a patient with non-mosaic Klinefelter's syndrome: Case report. Hum Reprod 15,1804-1806.
    • (2000) Hum Reprod , vol.15 , pp. 1804-1806
    • Ron-El, R.1    Strassburger, D.2    Gelman-Kohan, S.3    Friedler, S.4    Raziel, A.5    Appelman, Z.6
  • 81
    • 0026947541 scopus 로고
    • Expression of the X-inactivation-associated gene XIST during spermatogenesis
    • Salido EC, Yen PH, Mohandas TK and Shapiro LJ (1992) Expression of the X-inactivation-associated gene XIST during spermatogenesis. Nat Genet 2,196-199.
    • (1992) Nat Genet , vol.2 , pp. 196-199
    • Salido, E.C.1    Yen, P.H.2    Mohandas, T.K.3    Shapiro, L.J.4
  • 83
    • 0036813331 scopus 로고    scopus 로고
    • Cancer/testis antigens: An expanding family of targets for cancer immunotherapy
    • Scanlan MJ, Gure AO, Jungbluth AA, Old LJ and Chen YT (2002) Cancer/ testis antigens: An expanding family of targets for cancer immunotherapy. Immunol Rev 188,22-32.
    • (2002) Immunol Rev , vol.188 , pp. 22-32
    • Scanlan, M.J.1    Gure, A.O.2    Jungbluth, A.A.3    Old, L.J.4    Chen, Y.T.5
  • 84
    • 0018904978 scopus 로고
    • Barr bodies in testis with Klinefelter syndrome
    • Shamsuddin AK and Tang CK (1980) Barr bodies in testis with Klinefelter syndrome. Urology 15,74-76.
    • (1980) Urology , vol.15 , pp. 74-76
    • Shamsuddin, A.K.1    Tang, C.K.2
  • 85
    • 0033022705 scopus 로고    scopus 로고
    • Hormonal and genetic control of germ cell apoptosis in the testis
    • Sinha Hikim AP and Swerdloff RS (1999) Hormonal and genetic control of germ cell apoptosis in the testis. Rev Reprod 4,38-47.
    • (1999) Rev Reprod , vol.4 , pp. 38-47
    • Sinha Hikim, A.P.1    Swerdloff, R.S.2
  • 86
    • 0014669045 scopus 로고
    • Two types of tubules containing only Sertoli cells in adults with Klinefelter's syndrome
    • Skakkebaek NE (1969) Two types of tubules containing only Sertoli cells in adults with Klinefelter's syndrome. Nature 223,643-645.
    • (1969) Nature , vol.223 , pp. 643-645
    • Skakkebaek, N.E.1
  • 87
    • 0014676293 scopus 로고
    • Meiotic chromosomes in Klinefelter's syndrome
    • Skakkebaek NE, Philip J and Hammen R (1969) Meiotic chromosomes in Klinefelter's syndrome, Nature 221,1075-1076.
    • (1969) Nature , vol.221 , pp. 1075-1076
    • Skakkebaek, N.E.1    Philip, J.2    Hammen, R.3
  • 88
    • 0019879980 scopus 로고
    • Serum testosterone of boys with karyotype 47,XXY (Klinefelter's syndrome) at birth
    • Sorensen K, Nielsen J, Wohlert M, Bennett P and Johnsen SG (1981) Serum testosterone of boys with karyotype 47,XXY (Klinefelter's syndrome) at birth. Lancet 2,1112-1113.
    • (1981) Lancet , vol.2 , pp. 1112-1113
    • Sorensen, K.1    Nielsen, J.2    Wohlert, M.3    Bennett, P.4    Johnsen, S.G.5
  • 89
    • 3543100256 scopus 로고    scopus 로고
    • X-chromosome genetics and human cancer
    • Spatz A, Borg C and Feunteun J (2004) X-chromosome genetics and human cancer. Nat Rev Cancer 4,617-629.
    • (2004) Nat Rev Cancer , vol.4 , pp. 617-629
    • Spatz, A.1    Borg, C.2    Feunteun, J.3
  • 92
    • 0034889049 scopus 로고    scopus 로고
    • Mutation screening and CAG repeat length analysis of the androgen receptor gene in Klinefelter's syndrome patients with and without spermatogenesis
    • Suzuki Y, Sasagawa I, Tateno T, Ashida J, Nakada T, Muroya K and Ogata T (2001) Mutation screening and CAG repeat length analysis of the androgen receptor gene in Klinefelter's syndrome patients with and without spermatogenesis. Hum Reprod 16,1653-1656.
    • (2001) Hum Reprod , vol.16 , pp. 1653-1656
    • Suzuki, Y.1    Sasagawa, I.2    Tateno, T.3    Ashida, J.4    Nakada, T.5    Muroya, K.6    Ogata, T.7
  • 97
    • 4544237989 scopus 로고    scopus 로고
    • Inhibin B, predictive factor for testicular sperm recovery?
    • Vernaeve V, Brugnon F and Tournaye H (2004a) [Inhibin B, predictive factor for testicular sperm recovery?]. Gynecol Obstet Fertil 32,767-770.
    • (2004) Gynecol Obstet Fertil , vol.32 , pp. 767-770
    • Vernaeve, V.1    Brugnon, F.2    Tournaye, H.3
  • 98
    • 2442519305 scopus 로고    scopus 로고
    • Can biological or clinical parameters predict testicular sperm recovery in 47,XXY Klinefelter's syndrome patients?
    • Vernaeve V, Staessen C, Verheyen G, Van Steirteghem A, Devroey P and Tournaye H (2004b) Can biological or clinical parameters predict testicular sperm recovery in 47,XXY Klinefelter's syndrome patients? Hum Reprod 19,1135-1139.
    • (2004) Hum Reprod , vol.19 , pp. 1135-1139
    • Vernaeve, V.1    Staessen, C.2    Verheyen, G.3    Van Steirteghem, A.4    Devroey, P.5    Tournaye, H.6
  • 99
    • 0035071815 scopus 로고    scopus 로고
    • An abundance of X-linked genes expressed in spermatogonia
    • Wang PJ, McCarrey JR, Yang F and Page DC (2001) An abundance of X-linked genes expressed in spermatogonia. Nat Genet 27,422-426.
    • (2001) Nat Genet , vol.27 , pp. 422-426
    • Wang, P.J.1    McCarrey, J.R.2    Yang, F.3    Page, D.C.4
  • 100
    • 0034989099 scopus 로고    scopus 로고
    • Testicular ultrasonography and extended chromosome analysis in men with nonmosaic Klinefelter syndrome: A prospective study of possible predictive factors for successful sperm recovery
    • Westlander G, Ekerhovd E, Granberg S, Hanson L, Hanson C and Bergh C (2001) Testicular ultrasonography and extended chromosome analysis in men with nonmosaic Klinefelter syndrome: A prospective study of possible predictive factors for successful sperm recovery. Fertil Steril 75,1102-1105.
    • (2001) Fertil Steril , vol.75 , pp. 1102-1105
    • Westlander, G.1    Ekerhovd, E.2    Granberg, S.3    Hanson, L.4    Hanson, C.5    Bergh, C.6
  • 101
    • 0038511157 scopus 로고    scopus 로고
    • Low levels of serum inhibin B do not exclude successful sperm recovery in men with nonmosaic Klinefelter syndrome
    • Westlander G, Ekerhovd E and Bergh C (2003) Low levels of serum inhibin B do not exclude successful sperm recovery in men with nonmosaic Klinefelter syndrome. Fertil Steril 79,1680-1682.
    • (2003) Fertil Steril , vol.79 , pp. 1680-1682
    • Westlander, G.1    Ekerhovd, E.2    Bergh, C.3
  • 103
    • 0030031398 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor mediates programmed cell death
    • Yamada T, Horiuchi M and Dzau VJ (1996) Angiotensin II type 2 receptor mediates programmed cell death. Proc Natl Acad Sci USA 93,156-160.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 156-160
    • Yamada, T.1    Horiuchi, M.2    Dzau, V.J.3
  • 104
    • 0036115663 scopus 로고    scopus 로고
    • Morphometric and cytogenetic characteristics of testicular germ cells and Sertoli cell secretory function in men with non-mosaic Klinefelter's syndrome
    • Yamamoto Y, Sofikitis N, Mio Y, Loutradis D, Kaponis A and Miyagawa I (2002) Morphometric and cytogenetic characteristics of testicular germ cells and Sertoli cell secretory function in men with non-mosaic Klinefelter's syndrome. Hum Reprod 17,886-896.
    • (2002) Hum Reprod , vol.17 , pp. 886-896
    • Yamamoto, Y.1    Sofikitis, N.2    Mio, Y.3    Loutradis, D.4    Kaponis, A.5    Miyagawa, I.6
  • 105
    • 0034331256 scopus 로고    scopus 로고
    • Stem cell factor functions as a survival factor for mature Leydig cells and a growth factor for precursor Leydig cells after ethylene dimethane sulfonate treatment: Implication of a role of the stem cell factor/c-Kit system in Leydig cell development
    • Yan W, Kero J, Huhtaniemi I and Toppari J (2000a) Stem cell factor functions as a survival factor for mature Leydig cells and a growth factor for precursor Leydig cells after ethylene dimethane sulfonate treatment: Implication of a role of the stem cell factor/c-Kit system in Leydig cell development. Dev Biol 227,169-182.
    • (2000) Dev Biol , vol.227 , pp. 169-182
    • Yan, W.1    Kero, J.2    Huhtaniemi, I.3    Toppari, J.4
  • 106
    • 0034463078 scopus 로고    scopus 로고
    • Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis
    • Yan W, Samson M, Jegou B and Toppari J (2000b) Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis. Moll Endocrinol 14,682-699.
    • (2000) Mol Endocrinol , vol.14 , pp. 682-699
    • Yan, W.1    Samson, M.2    Jegou, B.3    Toppari, J.4
  • 107
    • 0033977849 scopus 로고    scopus 로고
    • Stem cell factor protects germ cells from apoptosis in vitro
    • Yan W, Suominen J and Toppari J (2000c) Stem cell factor protects germ cells from apoptosis in vitro. J Cell Sci 113,161-168.
    • (2000) J Cell Sci , vol.113 , pp. 161-168
    • Yan, W.1    Suominen, J.2    Toppari, J.3
  • 109
    • 0037384830 scopus 로고    scopus 로고
    • The CAG repeat polymorphism within the androgen receptor gene and maleness
    • Zitzmann M and Nieschlag E (2003) The CAG repeat polymorphism within the androgen receptor gene and maleness. Int J Androl 26,76-83.
    • (2003) Int J Androl , vol.26 , pp. 76-83
    • Zitzmann, M.1    Nieschlag, E.2
  • 110
    • 10344248169 scopus 로고    scopus 로고
    • X-chromosome inactivation patterns and androgen receptor functionality influence phenotype and social characteristics as well as pharmacogenetics of testosterone therapy in Klinefelter patients
    • Zitzmann M, Depenbusch M, Gromoll J and Nieschlag E (2004) X-chromosome inactivation patterns and androgen receptor functionality influence phenotype and social characteristics as well as pharmacogenetics of testosterone therapy in Klinefelter patients. J Clin Endocrinol Metab 89,6208-6217.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 6208-6217
    • Zitzmann, M.1    Depenbusch, M.2    Gromoll, J.3    Nieschlag, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.