Evidence that inhibited prostatic epithelial bud formation in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed C57BL/6J fetal mice is not due to interruption of androgen signalling in the urogenital sinus

Toxicological Sciences

Volumn 79, Issue 2, 2004, Pages 360-369

  Ko, Kinarm ^a,b   Theobald, H Michael ^a   Moore, Robert W ^a   Peterson, Richard E ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

2,3,7,8 tetrachlorodibenzo p dioxin (TCDD); Androgen receptor signaling pathway; C57BL 6J mouse fetus; Development; Hydroxyflutamide; Primary UGS mesenchymal cell culture; Prostate; Prostatic epithelial bud formation; Urogenital sinus (UGS)

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; HYDROXYFLUTAMIDE; LUCIFERASE; MESSENGER RNA; STEROID 5ALPHA REDUCTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL BUDDING; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; FETUS; GENE EXPRESSION; GENETIC TRANSFECTION; HORMONE INHIBITION; HORMONE RESPONSE; MALE; MESENCHYME CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PROMOTER REGION; PROSTATE EPITHELIUM; SIGNAL TRANSDUCTION; TISSUE CULTURE; UROGENITAL SINUS;

ANDROGEN ANTAGONISTS; ANIMALS; CELLS, CULTURED; DIHYDROTESTOSTERONE; ENVIRONMENTAL POLLUTANTS; EPITHELIUM; FEMALE; FETUS; FLUTAMIDE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LUCIFERASES; MALE; MATERNAL EXPOSURE; MESODERM; MICE; MICE, INBRED C57BL; PREGNANCY; PROSTATE; RECEPTORS, ANDROGEN; TESTIS; TESTOSTERONE; TETRACHLORODIBENZODIOXIN; UROGENITAL SYSTEM;

EID: 2942720929     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh111     Document Type: Article

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