Dietary seed oil rich in conjugated linolenic acid from bitter melon inhibits azoxymethane-induced rat colon carcinogenesis through elevation of colonic PPARγ expression and alteration of lipid composition

International Journal of Cancer

Volumn 110, Issue 6, 2004, Pages 896-901

  Kohno, Hiroyuki ^a   Yasui, Yumiko ^b   Suzuki, Rikako ^a,c   Hosokawa, Masashi ^b   Miyashita, Kazuo ^b   Tanaka, Takuji ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

Author keywords

Bitter melon; Chemoprevention; Colon carcinogenesis; Conjugated linolenic acid; PPAR

Indexed keywords

AZOXYMETHANE; CONJUGATED LINOLENIC ACID; LINOLENIC ACID; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG; VEGETABLE OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER MODEL; CHEMOPROPHYLAXIS; COLON CANCER; COLON CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; FAT INTAKE; LIPID COMPOSITION; MALE; MELON; MOMORDICA CHARANTIA; NONHUMAN; PLANT SEED; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; RAT;

ADENOCARCINOMA; ANIMALS; ANTICARCINOGENIC AGENTS; AZOXYMETHANE; COLONIC NEOPLASMS; DIETARY FATS; INCIDENCE; INTESTINAL MUCOSA; LINOLEIC ACIDS, CONJUGATED; MALE; MOMORDICA CHARANTIA; PHYTOTHERAPY; PLANT OILS; RATS; RATS, INBRED F344; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS;

EID: 2942621871     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20179     Document Type: Article

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