Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow

Journal of Immunology

Volumn 172, Issue 12, 2004, Pages 7408-7416

  Bleier, Joshua I ^a   Pillarisetty, Venu G ^a   Shah, Alaap B ^a   DeMatteo, Ronald P ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ADENOVIRUS; ANIMAL CELL; ARTICLE; BONE MARROW; CELLULAR IMMUNITY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; VIRUS RECOMBINANT;

EID: 2942558688     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.12.7408     Document Type: Article

References (39)

1. Taga, T., and T. Kishimoto. 1997. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15:797.
2. Hirano, T. 1998. Interleukin 6 and its receptor: ten years later. Int. Rev. Immunol. 16:249.
3. Diehl, S., and M. Rincon. 2002. The two faces of IL-6 on Th1/Th2 differentiation. Mol. Immunol. 39:531.
4. Van Snick, J. 1990. Interleukin-6: an overview. Annu. Rev. Immunol. 8:253.
5. Opal, S. M., and V. A. DePalo. 2000. Anti-inflammatory cytokines. Chest 117:1162.
6. Ceuppens, J. L., M. L. Baroja, K. Lorre, J. Van Damme, and A. Billiau. 1988. Human T cell activation with phytohemagglutinin: the function of IL-6 as an accessory signal. J. Immunol. 141:3868.
7. Diehl, S., J. Anguita, A. Hoffmeyer, T. Zapton. J. N. Ihle, E. Fikrig. and M. Rincon. 2000. Inhibition of Th1 differeniation by IL-6 is mediated by SOCS1. Immunity 13:805.
8. Diehl, S., C. W. Chow, L. Weiss, A. Palmetshofer. T. Twardzik, L. Rounds, E. Serfling, R. J. Davis, J. Anguita, and M. Rincon, 2002. Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation. J. Exp. Med. 196:39.
9. Houssiau, F. A., P. G. Coulie, and J. Van Snick. 1989. Distinct roles of IL-1 and IL-6 in human T cell activation. J. Immunol. 143:2520.
10. Akira, S., T. Taga, and T. Kishimoto. 1993. Interleukin-6 in biology and medicine. Adv. Immunol. 54:1.
11. + progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor. Blood 92:4778.
12. Ratta, M., F. Fagnoni, A. Curti, R. Vescovini, P. Sansoni, B. Oliviero, M. Fogli, E. Ferri, G. R. Della Cuna, S. Tura, et al. 2002. Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6. Blood 100:230.
13. Mitani, H., N. Katayama, H. Araki, K. Ohishi, K. Kobayashi, H. Suzuki, K. Nishii, M. Masuya, K. Yasukawa, N. Minami, and H. Shiku. 2000. Activity of interleukin 6 in the differentiation of monocytes to macrophages and dendritic cells. Br. J. Haematol. 109:288.
14. Chomarat, P., J. Banchereau, J. Davoust, and A. K. Palucka. 2000. IL-6 switches the differentiation of monocytes from dendritic cells to macrophages. Nat. Immunol. 1:510.
15. Brasel, K., T. De Smedt, J. L. Smith, and C. R. Maliszewski. 2000. Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures. Blood 96:3029.
16. Santiago-Schwarz, F., J. Tucci, and S. E. Carsons. 1996. Endogenously produced interleukin 6 is an accessory cytokine for dendritic cell hematopoiesis. Stem Cells 14:225.
17. Leenaerts, P. L., J. L. Ceuppens, J. Van Damme, P. Michielsen, and M. Waer. 1992. Evidence that stimulator cell-derived IL-6 and IL-1 are released in the mixed lymphocyte culture but are not requisite for responder T cell proliferation. Transplantation 54:1071.
18. Nicod, L. P., B. Galve-de Rochemonteix, and J. M. Dayer. 1990. Dissociation between allogeneic T cell stimulation and interleukin-1 or tumor necrosis factor production by human lung dendritic cells. Am. J. Respir. Cell Mol. Biol. 2:515.
19. + dendritic cells expressing indoleamine 2,3-dioxygenase. J. Immunol. 167:708.
20. + T cell-mediated suppression by dendritic cells. Science 299:1033.
21. Kopf, M., H. Baumann, G. Freer, M. Freudenberg, M. Lamers, T. Kishimoto, R. Zinkernagel, H. Bluethmann, and G. Kohler. 1994. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature 368:339.
22. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693.
23. Lutz, M. B., N. Kukutsch, A. L. Ogilvie, S. Rossner, F. Koch, N. Romani, and G. Schuler. 1999. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223:77.
24. Miller, G., V. G. Pillarisetty, A. B. Shah, S. Lahrs, Z. Xing, and R. P. DeMatteo. 2002. Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function. J. Immunol. 169:2875.
25. Pillarisetty, V. G., G. Miller, A. B. Shah, and R. P. DeMatteo. 2003. GM-CSF expands dendritic cells and their progenitors in mouse liver. Hepatology 37:641.
26. Miller, G., S. Lahrs, V. G. Pillarisetty, A. B. Shah, and R. P. DeMatteo. 2002. Adenovirus infection enhances dendritic cell immunostimulatory properties and induces natural killer and T-cell-mediated tumor protection. Cancer Res. 62:5260.
27. Rolink, A., F. Melchers, and J. Andersson. 1996. The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching. Immunity 5:319.
28. Kondo, M., D. C. Scherer, A. G. King, M. G. Manz, and I. L. Weissman. 2001. Lymphocyte development from hematopoietic stem cells. Curr. Opin. Genet. Dev. 11:520.
29. Miller, G., S. Lahrs, and R. P. DeMatteo. 2003. Overexpression of interleukin-12 enables dendritic cells to activate NK cells and confer systemic antitumor immunity. FASEB J. 17:728.
30. Kelleher, P., and S. C. Knight. 1998. IL-12 increases CD80 expression and the stimulatory capacity of bone marrow-derived dendritic cells. Int. Immunol. 10:749.
31. Dodge, I. L., M. W. Carr, M. Cernadas, and M. B. Brenner. 2003. IL-6 production by pulmonary dendritic cells impedes Th1 immune responses. J. Immunol. 170:4457.
32. Bernad, A., M. Kopf, R. Kulbacki, N. Weich, G. Koehler, and J. C. Gutierrez-Ramos. 1994. Interleukin-6 is required in vivo for the regulation of stem cells and committed progenitors of the hematopoietic system. Immunity 1:725.
33. Funk, J. O., H. Walczak, C. Voigtlander, S. Berchtold, T. Baumeister, P. Rauch, S. Rossner, A. Steinkasserer, G. Schuler, and M. B. Lutz. 2000. Cutting edge: resistance to apoptosis and continuous proliferation of dendritic cells deficient for TNF receptor-1. J. Immunol. 165:4792.
34. Ni, K., and H. O'Neill. 1999. Spleen stromal cells support haemopoiesis and in vitro growth of dendritic cells from bone marrow. Br. J. Haematol. 105:58.
35. Wilson, H. L., K. Ni, and H. C. O'Neill. 2000. Identification of progenitor cells in long-term spleen stromal cultures that produce immature dendritic cells. Proc. Natl. Acad. Sci. USA 97:4784.
36. Winzler, C., P. Rovere, M. Rescigno, F. Granucci, G. Penna, L. Adorini, V. S. Zimmermann, J. Davoust, and P. Ricciardi-Castagnoli. 1997. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J. Exp. Med. 185:317.
37. Samoilova, E. B., J. L. Horton, B. Hilliard, T. S. Liu, and Y. Chen. 1998. IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J. Immunol. 161:6480.
38. Jego, G., A. K. Palucka, J. P. Blanck, C. Chalouni, V. Pascual, and J. Banchereau. 2003. Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. Immunity 19:225.
39. + Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells. J. Immunol. 171:3684.