Activity of interleukin 6 in the differentiation of monocytes to macrophages and dendritic cells

British Journal of Haematology

Volumn 109, Issue 2, 2000, Pages 288-295

  Mitani, Hidetsugu ^a   Katayama, Naoyuki ^a   Araki, Hiroto ^a   Ohishi, Kohshi ^a   Kobayashi, Kyoko ^a   Suzuki, Hirohito ^a   Nishii, Kazuhiro ^a   Masuya, Masahiro ^a   Yasukawa, Kiyoshi ^b   Minami, Nobuyuki ^c   Shiku, Hiroshi ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOSOH CORPORATION   (Japan)

^c MIE UNIVERSITY HOSPITAL   (Japan)

Author keywords

Dendritic cells; Interleukin 6; Macrophages; Monocytes; Peripheral blood

Indexed keywords

COLONY STIMULATING FACTOR 1; GLYCOPROTEIN GP 130; GLYCOPROTEIN GP 39; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 11; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; LEUKEMIA INHIBITORY FACTOR; LIPOPOLYSACCHARIDE; NEUTRALIZING ANTIBODY; ONCOSTATIN M; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MACROPHAGE; MONOCYTE; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM;

ADULT; ANIMALS; ANTIGENS, CD1; ANTIGENS, CD14; CD40 LIGAND; CELL DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTORS, RECOMBINANT; HUMANS; IMMUNOPHENOTYPING; INTERLEUKIN-1; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034038677     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02020.x     Document Type: Article

References (43)

1. + dendritic cells and tartrate-resistant acid phosphatase-positive osteoclast-like multinucleated giant cells from human monocytos. Blood, 88, 4029-4039.
2. Allavena, P., Piemonti, L., Longoni, D., Bernasconi, S., Stoppacciaro, A., Ruco, L. & Mantovani, A. (1998) IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. European Journal of Immunology, 28, 359-369.
3. + dendritic precursor. Blood, 93, 2244-2252.
4. + hematopoietic progenitor cells of the hone marrow and peripheral blood. Cancer Research, 55, 1099-1104.
5. Bot, F.J., van Eijk, L., Broeders, L., Aarden, L.A. & Löwenberg, B. (1989) Interleukin-6 synergizes with M-CSF in the formation of macrophage colonies from purified human marrow progenitor cells. Blood, 73, 435-437.
6. Brossart, P., Grünebach, F., Stuhler, G., Reichardt, V.L., Möhle, R., Kanz, L. & Brugger, W. (1998) Generation of functional dendritic cells from adherent peripheral blood monocytes by CD40 ligation in the absence of granulocyte-macrophage colony-stimulating factor. Blood, 92, 4238-4247.
7. Caux, C., Dezutter-Dambuyant, C., Schmitt, D. & Banchereau, J. (1992) GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature, 360, 258-261.
8. Caux, C., Liu, Y.-J. & Banchereau, J. (1995) Recent advances in the study of dendritic cells and follicular dendritic cells. Immunology Today, 16, 2-5.
9. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF + TNFα. Journal of Experimental Medicine, 184, 695-706.
10. Clark, S.C. & Kamen, R. (1987) The human hematopoietic colony-stimulating factors. Science, 236, 1229-1237.
11. + hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells. Journal of Experimental Medicine, 185, 341-349.
12. Geissmann, F., Prost, C., Monnet, J.-P., Dy, M., Brousse, N. & Hermine, O. (1998) Transforming growth factor β1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells. Journal of Experimental Medicine, 187, 961-966.
13. Hart, D.N.J. (1997) Dendritic cells: unique leukocyte populations which control the primary immune response. Blood, 90, 3245-3287.
14. + peripheral blood progenitor cell and monocyte derived dendritic cells: a comparative analysis. British Journal of Haematology, 99, 490-499.
15. Hirata, Y., Taga, T., Hibi, M., Nakano, N., Hirano, T. & Kishimoto, T. (1989) Characterization of IL-6 receptor expression by monoclonal and polyclonal antibodies. Journal of Immunology, 143, 2900-2906.
16. Jansen, J.H., Kluin-Nelemans, J.C., van Damme, J., Wientjens, G.J.H.M., Willemze, R. & Fibbe, WE. (1992) Interleukin-6 is a permissive factor for monocytic colony formation by hematopoietic progenitor cells. Journal of Experimental Medicine, 175, 1151-1154.
17. Kishimoto, T. (1989) The biology of interleukin-6. Blood, 74, 1-10.
18. Kishimoto, T., Akira, S., Narazaki, M. & Taga, T. (1995) Interleukin-6 family of cytokines and gp130. Blood, 86, 1243-1254.
19. Mackenscn, A., Herbst, B., Köhler, G., Wolff-Vorbeck, G., Rosenthal, F.M., Veelken, H., Kulmburg, P., Schaefer, H.E., Mertelsmann, R. & Lindemann, A. (1995) Delineation of the dendritic cell lineage by generating large numbers of Birbeck granule-positive Langerhans cells from human peripheral blood progenitor cells in vitro. Blood, 86, 2699-2707.
20. Maeda, M., Noma, T., Hama, K. & Honjo, T. (1988) Application of a human T cell line derived from a Sézary syndrome patient for human interleukin 4 assay.Immunology Letters, 18, 247-254.
21. + progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor. Blood, 92, 4778-4791.
22. Metcalf, D. (1989) The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. Nature, 339, 27-30.
23. Moore, M.A.S. (1991) Clinical implications of positive and negative hematopoietic stem cell regulators. Blood, 78, 1-19.
24. Mosmann, T.R. (1994) Properties and functions of interleukin-10. Advances in Immunology, 56, 1-26.
25. Ogawa, M. (1993) Differentiation and proliferation of hematopoietic stem cells. Blood, 81, 2844-2853.
26. + peripheral blood monocytes. Journal of Immunology, 157, 3850-3859.
27. Piemonti, L., Bernasconi, S., Luini, W., Trobonjaca, Z., Minty, A., Allavena, P. & Mantovani, A. (1995) IL-13 supports differentiation of dendritic cells from circulating precursors in concert with GM-CSF. European Cytokine Network, 6, 245-252.
28. + progenitors in human bone marrow. Journal of Immunology, 149, 2681-2688.
29. Romani, N., Gruner, S., Brang, D., Kämpgen, E., Lenz, A., Trockenbacher, B., Konwalinka, G., Fritsch, P.O., Steinman, R.M. & Schuler, G. (1994) Proliferating dendritic cell progenitors in human blood. Journal of Experimental Medicine, 180, 83-93.
30. + hematopoietic precursor cells. Blood, 87, 535-544.
31. Saito, T., Taga, T., Miki, D., Futatsugi, K., Yawata, H., Kishimoto, T. & Yasukawa, K. (1993) Preparation of monoclonal antibodies against the IL-6 signal transducer. gp130, that can inhibit IL-6-mediated functions. Journal of Immunological Methods, 163, 217-223.
32. Sallusto, F. & Lanzavecchia, A. (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin-4 and downregulated by tumor necrosis factor α. Journal of Experimental Medicine, 179, 1109-1118.
33. Sallusto, F., Cella, M., Danieli, C. & Lanzavecchia, A. (1995) Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. Journal of Experimental Medicine, 182, 389-400.
34. + blood progenitors for anticancer therapy. Experimental Hematology, 23, 1463-1471.
35. Steinman, R.M. (1991) The dendritic cell system and its role in immunogenicity. Annual Review of Immunology, 9, 271-296.
36. Strobl, H., Bello-Fernandez, C., Reidl, E., Pickl, W.F., Majdic, O., Lyman, S.D. & Knapp, W. (1997) flt 3 ligand in cooperation with transforming growth factor-β1 potentiate in vitro development of Langerhans-type dendritic cells and allows single-cell dendritic cell cluster formation under serum-free conditions. Blood, 90, 1425-1434.
37. + bone marrow precursors cultured with c-kit ligand, granulocyte-macrophage colony-stimulating factor, and TNF-α. Journal of Immunology, 154, 5851-5861.
38. Taga, T., Narazaki, M., Yasukawa, K., Saito, T., Miki, D., Hamaguchi, M., Davis, S., Shoyab, M., Yancopoulos, G.D. & Kishimoto, T. (1992) Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130. Proceedings of the National Academy of Science of the United States of America, 89, 10998-11001.
39. Vole-Platzer, B., Stingl, G., Wolff, K., Hinterberg, W. & Schnedl, W. (1984) Cytogenetic identification of allogeneic epidermal Langerhans cells in a bone-marrow-graft recipient. New England Journal of Medicine, 310, 1123-1124.
40. Yamada, M., Furutani, Y., Notake, M., Yamaguchi, J.-i., Yamayoshi, M., Fukui, T., Nomura, H., Komiya, M., Kuwashima, J., Nakao, K., Sohmura, Y. & Nakamura, S. (1985) Efficient production of human tumour necrosis factor in Escherichia coli. Journal of Biotechnology, 3, 141-153.
41. + bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/ macrophage colony-stimulating factor and tumor necrosis factor α. Journal of Experimental Medicine, 182, 1111-1120.
42. + dendritic cells. Proceedings of the National Academy of Science of the United States of America, 93, 2588-2592.
43. Zurawski, G. & de Varies, J.E. (1994) Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunology Today, 15, 19-26.