Overexpression of Rac-1 small GTPase binding protein in oral squamous cell carcinoma

Journal of Oral and Maxillofacial Surgery

Volumn 62, Issue 6, 2004, Pages 702-707

  Liu, Shyun Yeu ^a,b   Yen, Ching Yu ^a   Yang, Shun Chun ^a   Chiang, Wei Fan ^a   Chang, Kuo Wei ^c  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RAC1 PROTEIN;

ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOUTH CARCINOMA; PROTEIN FAMILY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA;

EID: 2942555259     PISSN: 02782391     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joms.2004.02.002     Document Type: Article

References (22)

1. Parkin DM, Pisani P, Ferlay J: Global cancer statistics. Ca Cancer J Clin 49:33, 1999
2. Chang KW, Lin SC, Kwan PC, et al: Association of aberrant p53 and p21 (WAF1) immunoreactivity with the outcome of oral verrucous leukoplakia in Taiwan. J Oral Pathol Med 29:56, 2000
3. Chang KW, Kao SY, Tzeng RJ, et al: Multiple molecular alterations of FHIT in betel-associated oral carcinoma. J Pathol 196:300, 2002
4. Ko YC, Huang YL, Lee CH, et al: Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan. J Oral Pathol Med 24:450, 1995
5. Chen YK, Huang HC, Lin LM, et al: Primary oral squamous cell carcinoma: An analysis of 703 cases in southern Taiwan. Oral Oncol 35:173, 1999
6. Chin L, Tam A, Pomerantz J, et al: Essential role for oncogenic Ras in tumour maintenance. Nature 400:468, 1999
7. Irani K, Xia Y, Zweier JL, et al: Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275:1649, 1997
8. Caron E, Hall A: Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 282:1717, 1998
9. Evers EE, Zondag GC, Malliri A, et al: Rho family proteins in cell adhesion and cell migration. Eur J Cancer 36:1269, 2000
10. Braga VM, Machesky LM, Hall A, et al: The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J Cell Biol 137:1421, 1997
11. Yarbrough WG, Shores C, Witsell DL, et al: ras mutations and expression in head and neck squamous cell carcinomas. Laryngoscope 104:1337, 1994
12. Kuo MYP, Jeng CP, Chiang CP, et al: Mutations of Ki-ras oncogene codon 12 in betel quid chewing-related human oral squamous cell carcinoma in Taiwan. J Oral Pathol Med 23:70, 1994
13. Zohn IM, Campbell SL, Khosravi-Far R, et al: Rho family proteins and Ras transformation: The RHOad less traveled gets congested. Oncogene 17:1415, 1998
14. Malliri A, van der Kammen RA, Clark K, et al: Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours. Nature 417:867, 2002
15. Ridley AJ: Rho: Theme and variations. Curr Biol 6:1256, 1996
16. Ridley AJ: The GTP-binding protein Rho. Int J Biochem Cell Biol 29:1225, 1997
17. Mira JP, Benard V, Groffen J, et al: Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway. Proc Natl Acad Sci U S A 97:185, 2000
18. Khosravi-Far R, Solski PA, Clark GJ, et al: Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Mol Cell Biol 15:6443, 1995
19. Olson MF, Paterson HF, Marshall CJ: Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1. Nature 394:295, 1998
20. Chang KW, Lin SC, Mangold KA, et al: Alterations of adenomatous polyposis coli (APC) gene in oral squamous cell carcinoma. Int J Oral Maxillofac Surg 29:223, 2000
21. Rowinsky EK, Windle JJ, Von Hoff DD: Ras protein farnesyl-transferase: A strategic target for anticancer therapeutic development. J Clin Oncol 17:3631, 1999
22. Weber A, Bellmann U, Bootz F, et al: INK4a-ARF alterations and p53 mutations in primary and consecutive squamous cell carcinoma of the head and neck. Virchows Arch 441:133, 2002