Elimination of innate immune responses and liver inflammation by PEGylation of adenoviral vectors and methylprednisolone

Human Gene Therapy

Volumn 16, Issue 12, 2005, Pages 1439-1451

  De Geest, Bart ^a   Snoeys, Jan ^a   Van Linthout, Sophie ^a   Libyens, Joke ^a   Collen, Désiré ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALANINE AMINOTRANSFERASE; ALPHA CHEMOKINE; APOLIPOPROTEIN A1; CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; LIPOPOLYSACCHARIDE; MACROGOL DERIVATIVE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; METHYLPREDNISOLONE; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOMETHOXYPOLYETHYLENEGLYCOL; SUCCINIMIDYL SUCCINATE POLYETHYLENEGLYCOL; TRESYL MONOMETHOXYPOLYETHYLENEGLYCOL; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG CONJUGATION; FEMALE; GENE DELETION; GENE EXPRESSION; GENE TRANSFER; HEPATITIS; IMMUNE RESPONSE; LIVER CELL; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; SPLEEN CELL; THROMBOCYTE COUNT; THROMBOCYTOPENIA; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID; VIRUS PARTICLE;

ADENOVIRIDAE; ADENOVIRUS E1A PROTEINS; ANIMALS; CONJUGATION, GENETIC; CYTOKINES; FEMALE; IMMUNITY, NATURAL; INFLAMMATION; INTERLEUKIN-6; LIVER; METHYLPREDNISOLONE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEUTROPHILS; POLYETHYLENE GLYCOLS; RNA, MESSENGER;

ADENOVIRIDAE; ANIMALIA; MIRIDAE;

EID: 29244484292     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2005.16.1439     Document Type: Article

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