Platelet integrin α2 I-domain specific antibodies produced via domain specific DNA vaccination combined with variable gene phage display

Thrombosis and Haemostasis

Volumn 94, Issue 6, 2005, Pages 1318-1326

  Hughes, Darren L ^a   Stafford, Prachi ^a   Hamaia, Samir W ^a   Harmer, Ian J ^a   Schoolmeester, Anne ^c   Deckmyn, Hans ^c   Farndale, Richard W ^a   Ouwehand, Willem H ^a,b   Watkins, Nicholas A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NHS BLOOD AND TRANSPLANT   (United Kingdom)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

2 1 integrin; Collagen; DNA immunisation; Domain specific; Variable gene phage display

Indexed keywords

ALPHA2 INTEGRIN; COLLAGEN RECEPTOR; DNA VACCINE; EPITOPE; HYBRID PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TETANUS TOXOID; VERY LATE ACTIVATION ANTIGEN 2; MONOCLONAL ANTIBODY; PEPTIDE LIBRARY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY ISOLATION; ARTICLE; CELL TYPE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEAVY CHAIN; HUMAN; IMMUNIZATION; LIGHT CHAIN; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; RABBIT; SPLEEN CELL; THROMBOCYTE; VACCINATION; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; BAGG ALBINO MOUSE; BIOSYNTHESIS; CHEMISTRY; EPITOPE MAPPING; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METHODOLOGY; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BINDING SITES, ANTIBODY; BLOOD PLATELETS; CLONING, MOLECULAR; EPITOPE MAPPING; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN VARIABLE REGION; INTEGRIN ALPHA2BETA1; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; RABBITS; RECOMBINANT FUSION PROTEINS; VACCINES, DNA;

EID: 29244472795     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH05-06-0410     Document Type: Article

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